Clinical trials: Hyperglycemia, active
Obesity, Diabetes
Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults
Background: Diabetes and obesity are chronic diseases. They can affect blood flow and how the body processes nutrients, and complications over time can lead to early death.
- Conditions
- Obesity, Diabetes, Metabolic Disorders
- Trial name
- NCT07388537
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Critical Illness, Hyperglycemia
Stress Hyperglycemia Ratio and Glucose Variability in Critically Ill Patients
This prospective cohort study aims to evaluate the stress hyperglycemia ratio and glucose variability among critically ill patients admitted to the intensive care unit.
- Trial name
- NCT07892222
- Volunteers
- 75 people
- Sponsor
- Assiut University
End Stage Kidney Disease (ESKD), Hyperglycaemia
Unmasking Diabetes in Dialysis With Continuous Glucose Monitoring
This study will evaluate whether Continuous Glucose Monitoring (CGM) can identify previously unrecognized diabetes and clinically significant hyperglycemia in adults with end-stage kidney disease (ESKD) receiving hemodialysis who…
- Conditions
- End Stage Kidney Disease (ESKD), Hyperglycaemia, Diabetes
- Trial name
- NCT07880795
- Testing
- Continuous Glucose Monitoring (CGM)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Emory University
Gestational Diabetes, Hyperglycemia
Early Investigation of Glucose Monitoring After Gestational Diabetes Pilot
One third of women with gestational diabetes (GDM), diabetes diagnosed during pregnancy, have abnormal glucose levels within 3 years after pregnancy, but follow up is low.
- Trial name
- ENGAGED (NCT06184373)
- Testing
- Continuous glucose monitor, Oral Glucose Tolerance Test, Hemoglobin A1c
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Obesity, Gestational Diabetes
Strategies for Implementing a Postpartum Lifestyle Intervention in WIC Clinics
The primary objective of the STRIVE study is to compare two implementation strategies for Diabetes Prevention Program delivery: an in-person health coach strategy (standard 24 in-person sessions at WIC clinics) vs.
- Conditions
- Obesity, Gestational Diabetes, Lifestyle, Healthy, Glucose Intolerance During Pregnancy
- Trial name
- STRIVE (NCT06116149)
- Testing
- In-person health coach delivery of the GLB, Technology-assisted health coach delivery of the GLB
- Where
- United States
- Volunteers
- 722 people, healthy volunteers welcome
- Sponsor
- Tulane University
Respiratory Aspiration, Hyperglycemia
Maltodextrin Versus Sugar Water Carbohydrate Loading and Gastric Volume in Geriatric Lower Limb Orthopedic Surgery
Before surgery, patients are asked to fast so the stomach is empty and stomach contents cannot enter the lungs during anesthesia. Long fasting is uncomfortable and can raise blood sugar and stress responses in older adults.
- Conditions
- Respiratory Aspiration, Hyperglycemia, Inflammation
- Trial name
- CHO-GERIGAS (NCT07872683)
- Testing
- Maltodextrin carbohydrate drink, Sugar water
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Udayana University
Elevated Blood Glucose
Whole-Food Magnesium for Mental and Cardiometabolic Health
This randomized, double-blind, placebo-controlled clinical trial will evaluate the effects of daily supplementation with E-Z Mg™, a commercially available whole-food-based magnesium supplement, on sleep, mood, fatigue, and…
- Trial name
- NCT07865351
- Testing
- Low-Dose Whole-Food-Based Magnesium Supplement, Moderate-Dose Whole-Food-Based Magnesium Supplement
- Volunteers
- 45 people
- Sponsor
- George Mason University
Acromegaly Due to Pituitary Adenoma, Hyperglycemia
Managing Pasireotide-associated Hyperglycaemia in Acromegaly With Ketogenic Diet
Rationale: Pasireotide is a second line medical treatment for acromegaly that can add value for patients with insufficient control of disease on 1st generation SRL, or 1st generation SRL + pegvisomant.
- Conditions
- Acromegaly Due to Pituitary Adenoma, Hyperglycemia, Ketogenic Diet, Standard Care Control
- Trial name
- PasiAcroKeto (NCT07866846)
- Testing
- Ketogenic diet, Diabetes Medication
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Leiden University Medical Center
PreDiabetes, Impaired Glucose Tolerance
Effect of Probiotics Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes.
Pre diabetes (PD) is a term that refers to alterations in blood glucose levels, including impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or both, and increase in glycated hemoglobin (HbA1c), all this factors…
- Conditions
- PreDiabetes, Impaired Glucose Tolerance, Hyperglycemia, Resistance, Insulin
- Trial name
- NCT04341571
- Testing
- Probiotics, Metformin
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- University of Guadalajara
Diabetes Mellitus, Type 2, Lifestyle
Real-time Engagement for Learning to Effectively Control Type 2 Diabetes
The goal of this clinical trial is to learn if a new smartphone app that pairs glucose and exercise data will help adolescents and young adults with type 2 diabetes improve glycemic control.
- Conditions
- Diabetes Mellitus, Type 2, Lifestyle, Hyperglycemia, Physical Inactivity
- Trial name
- REFLECT2D (NCT06375460)
- Testing
- Focused App Prompt, No App Prompt
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pittsburgh
Critical Illness, Hyperglycemia
Prognostic Value of Stress Hyperglycemia Ratio in Critically Ill Patients
Critically ill patients admitted to intensive care units (ICUs) frequently develop elevated blood sugar levels (hyperglycemia) as a result of acute illness-related stress, even if they do not have diabetes.
- Conditions
- Critical Illness, Hyperglycemia, Acute Kidney Injury, Multiple Organ Failure
- Trial name
- NCT07853911
- Volunteers
- 230 people
- Sponsor
- Assiut University
Diabetes, Gestational, Pregnancy in Diabetics
Westlake Precision Birth Cohort
The Westlake Precision Birth Cohort (WeBirth) is a prospective cohort study among women with hyperglycemia during pregnancy and their offspring living in Hangzhou, China.
- Conditions
- Diabetes, Gestational, Pregnancy in Diabetics, Intrauterine Hyperglycemia
- Trial name
- WeBirth (NCT04060056)
- Testing
- Standardized breakfast, Standardized snack, Standardized lunch
- Where
- China
- Volunteers
- 2,001 people
- Sponsor
- Westlake University
Gestational Diabetes Mellitus, Intrauterine Hyperglycemia
Wenzhou Gestational Diabetes Cohort
The Wenzhou Gestational Diabetes Cohort (WGDC) is a prospective cohort study among women with gestational diabetes mellitus (GDM) during pregnancy and their offspring living in Wenzhou, China.
- Conditions
- Gestational Diabetes Mellitus, Intrauterine Hyperglycemia, Birth Outcome, Adverse, Nutrition, Healthy
- Trial name
- WGDC (NCT05794152)
- Testing
- Standardized breakfast, Standardized snack, Standardized lunch
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Westlake University
Pancreatic Neoplasms, Pancreatic Cysts
Studies of Blood Glucose and the Microbiome in Tumors and Cysts of the Pancreas
This prospective, single-center observational study investigates whether continuous glucose monitoring (CGM, 14 days) and gut microbiota composition (from a fecal sample) reveal patterns specific to pancreatic cancer, aiming to…
- Conditions
- Pancreatic Neoplasms, Pancreatic Cysts, Hyperglycemia, Prediabetes
- Trial name
- NCT07843147
- Volunteers
- 100 people
- Sponsor
- Umeå University
Type 2 Diabetes Mellitus (T2DM), Hyperglycemia Due to Type 2 Diabetes Mellitus
Multilingual Voice Calls to Adjust Long-Acting Insulin for Adults With Type 2 Diabetes and Low Health Literacy in Pakistan
This study will evaluate whether a multilingual, feature-phone interactive voice response (IVR) system with human-verified basal insulin titration improves glycemic control compared with standard clinic-based insulin titration…
- Trial name
- VOICE-TITR-PK (NCT07729501)
- Testing
- Multilingual IVR-Supported Basal Insulin Titration, Standard Clinic-Based Basal Insulin Titration
- Where
- Pakistan
- Volunteers
- 220 people
- Sponsor
- Shifa International Hospital
Diabetes Mellitus, Type 2, Hyperglycemia Due to Type 2 Diabetes Mellitus
Pre-emptive Insulin to Prevent High Glucose After a Knee Steroid Injection in Adults With Type 2 Diabetes
Steroid injections used to treat painful joints can temporarily increase glucose levels in people with type 2 diabetes. This study will test whether a short course of pre-emptive neutral protamine Hagedorn, NPH, insulin can…
- Conditions
- Diabetes Mellitus, Type 2, Hyperglycemia Due to Type 2 Diabetes Mellitus, Osteoarthritis, Knee
- Trial name
- PREVENT-SIH (NCT07757464)
- Testing
- Insulin Isophane Human, NPH, Pre-emptive Algorithm, Triamcinolone Acetonide Knee Injection
- Where
- Pakistan
- Volunteers
- 125 people
- Sponsor
- Shifa International Hospital
Pancreatic Cancer, PDAC - Pancreatic Ductal Adenocarcinoma
Monitoring and Managing Glucose Levels in People With Pancreatic Cancer
This study will investigate the prevalence of hyperglycemia (high blood sugar) in approximately 50 participants with pancreatic cancer.
- Conditions
- Pancreatic Cancer, PDAC - Pancreatic Ductal Adenocarcinoma, Hyperglycemia
- Trial name
- PEGASUS (NCT05132244)
- Testing
- Glucose Measurements via Blood Draw
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- British Columbia Cancer Agency
Breast Cancer, Hyperglycemia
Risk-Stratified Management of Inavolisib-Induced Hyperglycemia and Patient Adherence
Inavolisib is an effective targeted therapy for certain patients with breast cancer, but it may cause high blood sugar (hyperglycemia) as a side effect.
- Trial name
- NCT07817056
- Testing
- Risk-stratified hyperglycemia management strategy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Hyperglycemia, Diabetes Mellitus
Early Detection Initiative for Pancreatic Cancer
The Early Detection Initiative for Pancreatic Cancer is a multi-center prospective study to determine if algorithm-based screening in patients with glycemically defined new onset hyperglycemia and diabetes has the potential for…
- Conditions
- Hyperglycemia, Diabetes Mellitus, Pancreas Ductal Adenocarcinoma
- Trial name
- EDI (NCT04662879)
- Testing
- Enriching New-onset Diabetes for Pancreatic Cancer (ENDPAC) score, Abdominal imaging
- Where
- 2 sites in United States
- Volunteers
- 8,869 people
- Sponsor
- Pancreatic Cancer Action Network
Diabetes Type 2 on Insulin, Hypoglycemia (Diabetic)
Comparing Glycemic Outcomes of Carbohydrate Counting vs. Fixed Mealtime Insulin Dosing in Hospitalized Patients With Hyperglycemia
The study compares two current practices for calculating insulin dose for admitted patients: flexible fixed mealtime dosing based on percent of meal eaten and carbohydrate counting based on amount of carbohydrates eaten.
- Conditions
- Diabetes Type 2 on Insulin, Hypoglycemia (Diabetic), Hyperglycemia Due to Type 2 Diabetes Mellitus
- Trial name
- MEND (NCT07808398)
- Testing
- Carbohydrate-counting-based prandial rapid-acting insulin dosing, Flexible fixed mealtime rapid-acting insulin dosing based on percentage of meal consumed
- Volunteers
- 500 people
- Sponsor
- Mayo Clinic