Clinical trials: Spasticity as Sequela of Stroke
Stroke, Spasticity as Sequela of Stroke
Dynamic Lycra Orthosis as an Adjunct to Botulinum Toxin-A Injection for Post-stroke Spasticity
Upper extremity splints are one of the nonpharmacologic treatments used to treat hypertonicity after stroke. The purpose of splinting is to support, to position, to immobilize, to prevent contracture and deformities, to reduce…
- Conditions
- Stroke, Spasticity as Sequela of Stroke, Upper Limb Hypertonia
- Trial name
- NCT03546959
- Testing
- Lycra sleeve, Rehabilitation, Botulinum Toxin
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University
Spasticity as Sequela of Stroke
Phenol and Botulinum Toxin vs Botulinum Toxin Alone for Post-Stroke Upper-Limb Spasticity
This study aims to evaluate the efficacy of a combined treatment approach for post-stroke upper limb spasticity using phenol neurolysis and botulinum toxin (BoNT).
- Trial name
- NCT07440173
- Testing
- phenol neurolysis, Botulinum Toxin - A injections
- Volunteers
- 60 people
- Sponsor
- Assiut University
Stroke, Spasticity as Sequela of Stroke
Radial Extracorporeal Shock Wave Therapy as an Adjunct to Botulinum Toxin Type A for Post-Stroke Lower Limb Spasticity (SOLUTION)
The goal of this pilot clinical trial is to determine whether radial extracorporeal shock wave therapy (rESWT), when used as an adjunct to ultrasound-guided botulinum toxin type A (BoNT-A) injections, can enhance the therapeutic…
- Conditions
- Stroke, Spasticity as Sequela of Stroke, Lower Limb Spasticity, Upper Motor Neuron Syndrome
- Trial name
- SOLUTION (NCT07875868)
- Testing
- Radial shock Wave therapy (3000 pulses, 5 Hz, 2.5 bar)., Ultrasound-guided abobotulinumtoxin A
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Parc de Salut Mar
Stroke, Spasticity as Sequela of Stroke
Effect of ESWT Applied After Botulinum Toxin Injection on Ankle Spasticity in Stroke Patients.
Stroke is the second most common cause of death and the third most important cause of disability worldwide, with an annual death rate of 5.5 million.
- Trial name
- NCT06126523
- Testing
- Radial Extracorporeal Shock Wave Therapy ONCE, Radial Extracorporeal Shock Wave Therapy TWİCE
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Saglik Bilimleri Universitesi
Brain Injuries, Disorder of Consciousness
Long Term Effects of Soft Splints on Stroke Patients and Patients With Disorders of Consciousness
The purpose of this study is to assess the effects on upper limb spasticity of soft splints worn during three weeks three hours a day by patients with stroke or disorders of consciousness.
- Conditions
- Brain Injuries, Disorder of Consciousness, Stroke, Spasticity as Sequela of Stroke
- Trial name
- NCT03008486
- Testing
- Real soft splint (6 cm)
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Géraldine Martens
Stroke, Spasticity as Sequela of Stroke
Robotic Hand Rehabilitation
The performance of activities of daily living (ADL) depends to a large extent on the functionality of the upper limb and hand. Stroke is the leading cause of disability worldwide, with a significant individual, family and…
- Conditions
- Stroke, Spasticity as Sequela of Stroke, Upper Limb
- Trial name
- RoHa-S (NCT05983822)
- Testing
- Technological Group, Conventional Treatment
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Spasticity as Sequela of Stroke
Cryoneurolysis for Spasticity Treatment: Long-term Clinical Outcomes and Mechanisms in the Central Nervous System
Spasticity can make regular daily activities difficult or impossible. Cryoneurolysis is a new technique to treat spasticity that is currently being tested.
- Trial name
- NCT06958289
- Testing
- Cryoneurolysis
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Sue Peters
Spasticity as Sequela of Stroke, Spastic Hemiplegia
Modulation of Upper Limb Spasticity Post-Stroke
Stroke is one of the commonest causes of severe disability in adults. Stroke often results in spasticity and motor impairments in the upper limb.
- Conditions
- Spasticity as Sequela of Stroke, Spastic Hemiplegia, Upper Extremity Dysfunction
- Trial name
- NCT05069480
- Testing
- Virtual reality-based training equipment., Traditional physical therapy program
- Where
- Saudi Arabia
- Volunteers
- 38 people
- Sponsor
- Umm Al-Qura University
Spasticity as Sequela of Stroke, Gait, Hemiplegic
Motor Imagery Technique on Lower Limb Function Among Stroke Patients.
To determine the effects of motor imagery technique on lower limb function among stroke patient. To determine the effects of motor imagery technique on lower limb spasticity among stroke patients.
- Conditions
- Spasticity as Sequela of Stroke, Gait, Hemiplegic, Quality of Life
- Trial name
- NCT04707755
- Testing
- Motor imagery technique, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Spasticity as Sequela of Stroke, Nerve Transfers
Nerve Transfers in Post-stroke Spasticity
Stroke is nowadays a leading cause of disability with devastating sequelae. Upper limb spasticity is one of them. Nevertheless, not all the muscles are equally affected, as some may turn spastic or paretic and other remain…
- Trial name
- NCT04437056
- Testing
- Cognitive nerve transfers to spastic upper extremity muscles in stroke patients
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Spasticity as Sequela of Stroke
Dose-response Relationship of Botullinum Toxin (DWP 450) for Finger Flexor Spasticity
Study Design: Randomized Single Blind Study Objective: To determine the dose relationship of DWP 450 for finger flexor spasticity Subjects: 78 patients with upper extremity spasticity after CVA Inclusion criteria: Patient who…
- Trial name
- NCT03517319
- Testing
- Normal Saline 0.9% 1.2 ml, Clostridium Botulinum Toxin Type A (Nabota, DWP 450) 15 U, Clostridium Botulinum Toxin Type A (Nabota, DWP 450) 30 U
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Seoul National University Hospital
Stroke, Stroke, Ischemic
Passive Tactile Stimulation for Stroke Rehabilitation
Stroke can lead to weakness and spasticity in the arm or hand. The purpose of this study is to optimize the design of gentle vibratory stimulation delivered to the hands of individuals with chronic stroke, and explore the effect…
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Spasticity as Sequela of Stroke
- Trial name
- PTS (NCT03814889)
- Testing
- Vibration pattern, No vibration
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Stanford University
Aromatherapy, Spasticity as Sequela of Stroke
Aromatherapy on Upper Limb Spasticity on Stroke Survivors
This study employed a double-arm, pre- and post-test design. Stroke survivors aged 65 or above with post-stroke upper limbs spasticity were recruited from two RCHEs in Hong Kong between February and June 2025, and were divided…
- Trial name
- NCT07286825
- Testing
- massage oil with a mixture of sweet marjoram essential oil and fractionated coconut organic carrier oil, plain fractionated coconut organic carrier oil
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Hong Kong Metropolitan University
Stroke, Spasticity as Sequela of Stroke
Different Treatment Methods Effect on Upper Extremity Spasticity and Decreased Functionality After Stroke
The aim of our study is to objectively and clearly determine the differences between the Spasticity and Decreased Functionality in the Upper Extremity Flexor Group Muscles After Stroke, the Vibration, mBZHT and Physiotherapy and…
- Conditions
- Stroke, Spasticity as Sequela of Stroke, Limitation, Mobility
- Trial name
- NCT05747950
- Testing
- Vibration, Modified Constraint-İnduced Movement Therapy, Conventional Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Zuhal Şevval Gökdere
Stroke, Hemiparesis
Recovery of Motor Skills With the Use of Artificial Intelligence and Computer Vision
To investigate the impact of algorithms utilizing artificial intelligence technology and computer vision on the recovery of motor functions within the context of rehabilitation practice for patients who have experienced a…
- Conditions
- Stroke, Hemiparesis, Spasticity as Sequela of Stroke, Dysmetria
- Trial name
- NCT06183970
- Testing
- AssistI patients, Habilect patients
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Spasticity as Sequela of Stroke
A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development
This study will monitor patients during the first year following their stroke. Stroke is a very serious condition where there is a sudden interruption of blood flow in the brain.
- Trial name
- EPITOME (NCT06055725)
- Where
- 55 sites in United States, France and 5 more
- Volunteers
- 1,057 people
- Sponsor
- Ipsen
Spasticity as Sequela of Stroke, Stroke
Prevalence of Postural Patterns of Upper Extremity.
A high number of patient with stroke develops spasticity of the upper extremity, this clinical sign of damage of 1 motoneuro (MN), causes postures and patterns of abnormal movement, due to the hyperexcitability of the MN and the…
- Conditions
- Spasticity as Sequela of Stroke, Stroke, Upper Extremity Paresis
- Trial name
- Patterns (NCT03588832)
- Testing
- Evaluation Upper Extremity patterns.
- Where
- Chile
- Volunteers
- 600 people
- Sponsor
- Universidad de La Frontera
Spasticity as Sequela of Stroke
Repetitive Transcranial Magnetic Stimulation in Post Stroke Upper Limb Spasticity
The reticulospinal pathway (RSP) is at the center of spasticity mechanism. The RSP indirectly synapses with motor neurons via interneurons in the ventromedial intermediate zone in both halves of the spinal cord, and directly…
- Trial name
- NCT04063995
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Izmir Katip Celebi University
Spasticity as Sequela of Stroke
Immediate Effect of Johnstone's Pressure Splint Added to Stretching on the Spasticity in Cerebrovascular Disease.
TITLE: Immediate effect of Johnstone's Pressure Splint added to Stretching on the spasticity of elbow flexors and wrist in Cerebrovascular Disease (CVD).
- Trial name
- NCT03675958
- Testing
- Johnstone's Pressure Splint, Stretching
- Volunteers
- 20 people
- Sponsor
- Universidad Industrial de Santander
Spasticity as Sequela of Stroke
EXOPULSE Mollii Suit, Motor Function & Stroke (EXOSTROKE)
Spasticity is a common and debilitating complication in neurological conditions such as multiple sclerosis, cerebral palsy, and stroke.
- Trial name
- EXOSTROKE (NCT06702163)
- Testing
- EXOPULSE MOLLII SUIT (active)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Institut De La Colonne Vertebrale Et Des Neurosciences