Clinical trials: Implant Infection
Upper Extremity Deep Vein Thrombosis
Major Complications Related to PICC and Midline Insertion
Most important peripherally inserted central catheter (PICC) and Midline complications are thrombosis and catheter related blood stream infections.
- Trial name
- PICC/MIDLINE (NCT02489721)
- Testing
- PICC and Midline
- Where
- Italy
- Volunteers
- 547 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
Orthopedic Surgery, Fracture Related Infection
Comparison of Debridement, Antibiotic, Implant Retention and Implant Exchange in Early-stage Fracture-related Infections
This study aims to compare the clinical outcomes of debridement, antibiotics, and implant retention (DAIR) and implant removal/replacement methods used in the treatment of fracture-related infections, and to determine the…
- Conditions
- Orthopedic Surgery, Fracture Related Infection, Debridement, Implant Retention
- Trial name
- DAIR (NCT07669714)
- Testing
- DAIR, Implant removal/replacement
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Antalya Health Sciences University
Staphylococcus Epidermidis Positive Blood Culture
Invasive Markers of Staphylococcus Epidermidis
The purpose of the study is to identify biomarkers allowing the distinction between invasive and non-invasive strains of Staphylococcus epidermidis.
- Trial name
- SepiNGS (NCT03374371)
- Testing
- high-throughput sequencing
- Where
- France
- Volunteers
- 320 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Incisional Hernia, Peritonitis
Prophylactic Implantation of Biologic Mesh in Peritonitis
Patients undergoing emergency surgery for peritonitis are at increased risk of abdominal wall-related complications. In patients with peritonitis the risk of incisional hernia (IH) is extremely elevated.
- Trial name
- NCT04681326
- Testing
- biological prosthesis
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Peri-implant Mucositis
Treatment of Inflammation Around Implants With a Laser or an Ultrasonic Device
The goal of the clinical trial is to compare laser therapy with ultrasonic therapy in patients with inflammation in the tissue surrounding single implants (peri-implant mucositis).
- Trial name
- NCT05772299
- Testing
- Er:Yag laser, EMS ultrasound
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Kristianstad University
Dental Implant Failed, Implant Complication
Characterizing the Inflammation Around Dental Implants: Bacterial Infection, Hypersensitivity or Both?
The use of titanium dental implants has become a common modern treatment to restore teeth. Although the success rate of dental implants is high, inflammation around the dental implant still occurs.
- Conditions
- Dental Implant Failed, Implant Complication, Implant Site Infection, Implant Site Reaction
- Trial name
- NCT06515886
- Testing
- Clinical Examination, Peri-implant crevicular fluid
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Edentulous Alveolar Ridge, Peri-Implantitis
Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry
The goal of this clinical trial is to learn how different materials used in dental implants affect the surrounding gum tissue in adults who need dental implants.
- Conditions
- Edentulous Alveolar Ridge, Peri-Implantitis, Peri-implant Mucositis, Prosthetic Infection
- Trial name
- NCT06554041
- Testing
- Dental Crown with Titanium-Abutment, Dental Crown with PEEK (Polyetheretherketone)-Abutment, Dental Crown with Zirconia-Abutment
- Where
- Lithuania
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Cardiovascular Infections, Peripheral Vascular Disease
Placement of Peripherally Inserted Central Venous Catheters (PICC) in Children Guided by Ultrasound
Aimed to compare the success in the peripheral intravenous puncture (PIP), progression and placement of PICC in children, according to the use of Doppler vascular ultrasound (DVUS) or traditional method; to identify the influence…
- Trial name
- NCT01279642
- Testing
- ultrasound, traditional puncture
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Taurolidine Lock Solution
Survey of Practices Regarding the Use of Taurolidine Lock Solutions in Patients With Insertion of a Peripherally Inserted Central Catheter (PICC) in a Vascular Access Unit
The primary objective of this study is to describe current practices regarding the administration of taurolidine lock solutions in relation to medical prescriptions for patients who have undergone peripherally inserted central…
- Trial name
- TAURO-USE2 (NCT07259421)
- Volunteers
- 45 people
- Sponsor
- University Hospital, Grenoble
Infections
Efficacy and Safety of Antimicrobial Durations Treatment of Infections Associated With Osteosynthesis Material
Infections associated with osteosynthesis material are among the most feared and challenging complications of trauma surgery and can lead to total function loss or limb amputation when complete recovery is to be expected without…
- Trial name
- DURATIOM (NCT05294796)
- Testing
- Short course of antibiotherapy, Long course of antibiotherapy
- Where
- 29 sites in Spain
- Volunteers
- 364 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Peri-Implantitis, Peri-implant Mucositis
Peri-implant Conditions Mimic Periodontal Conditions
Except for patients with referred clinical bruxism and uncontrolled medical conditions, the study included 123 implants with implanted fixed prostheses that had lasted at least six months after functional prosthetic loading.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Peri-implant Health, Periodontitis
- Trial name
- NCT06128850
- Testing
- disease
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Peri-Implantitis, Peri-implant Mucositis
Characterizing the Inflammation Around Dental Implants
The use of titanium dental implants has become a common modern treatment to restore teeth. Although the success rate of dental implants is high, inflammation around the dental implant still occurs.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Implant Site Reaction, Implant Site Infection
- Trial name
- NCT05675241
- Testing
- Clinical examination of a dental implant, Radiological Examination, Peri-implant crevicular fluid sample collection
- Where
- Canada
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- McGill University
Pneumothorax, Hydrothorax
KatGuide Method Versus Conventional Method at Insertion of Chest Tube
The purpose of this study is to investigate whether if KatGuide (a new developed medical device) improves the placing of a large bore chest tube in the pleural cavity compared to the conventional method.
- Conditions
- Pneumothorax, Hydrothorax, Hemothorax, Empyema
- Trial name
- KatGuide (NCT01522885)
- Testing
- KatGuide versus conventional method (forceps), Chest tube insertion
- Where
- 4 sites in Denmark
- Volunteers
- 109 people
- Sponsor
- Niels Katballe
Intubated Patient Requiring a Gastric Tube
Impact of the Choice of Gastric Tube Placement Sites on the Incidence of Ventilator Associated Pneumonia
In intensive care, many gastric tubes are inserted on a regular basis. There are different practices in terms of the location of the gastric tube.
- Trial name
- SONG (NCT05915663)
- Testing
- nasogastric tube and orogastric tube, orogastric tube and nasogastric tube
- Where
- 16 sites in France
- Volunteers
- 2,400 people
- Sponsor
- Centre Hospitalier le Mans
Cytomegalovirus Retinitis, HIV Infections
Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis
To compare cidofovir with a commonly used treatment regimen, ganciclovir given by mouth (oral) and through an eye device (intraocular) , in order to determine the safety and effectiveness of cidofovir in preventing vision loss in…
- Trial name
- NCT00000894
- Testing
- Cidofovir, Probenecid, Ganciclovir
- Where
- 12 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Catheter Infection
Identifying Local Signs at the Catheter Insertion Site With Artificial Intelligence
Deepcath is the first step to the introduction of artificial intelligence in catheter care. A better use of visualisation of catheter exit site should be used not only by the HCWs but also by the patients and their family.
- Trial name
- DeepCath (NCT05440396)
- Testing
- Photographs collection phase
- Where
- 4 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Outcome Rea
Uveitis, Posterior
Fluocinolone Acetonide Intravitreal Implant 0.18 mg in the Treatment of Chronic Non-Infectious Posterior Segment Uveitis
A study to evaluate the safety and efficacy of YUTIQ® 0.18 mg intravitreal implant for the management of chronic non-infectious posterior segment uveitis (intraocular inflammation) that has responded to previous steroid therapy.
- Trial name
- NCT05322070
- Testing
- Fluocinolone Acetonide Intravitreal Implant 0.18 mg
- Where
- 23 sites in United States
- Volunteers
- 125 people
- Sponsor
- Alimera Sciences
Prosthesis-Related Infections, Equipment Failure
Medico-economic Evaluation of Strategies for the Lead Extraction of Implantable Defibrillator and Pacemakers
The growing use and the expanding indications for cardiovascular implantable electronic devices (CIEDs) have been associated to an increase of device removal.
- Conditions
- Prosthesis-Related Infections, Equipment Failure, Heart Failure, Arrhythmias
- Trial name
- GAINE LASER (NCT03121183)
- Testing
- Laser sheath, Implantable Cardiac Device lead extraction
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Clermont-Ferrand
Infections
Antibiotic Therapy is Not Necessary to Implant Totally Implantable Venous Access Devices: Randomized Prospective Study
BACKGROUND: The growing use of totally implantable venous access devices (TIVAD) has caused the simultaneous increase of various complications.
- Trial name
- TIVAD (NCT00665873)
- Testing
- PORT-A-CATH (Smiths Medical Inc., MN), Amoxicillin and clavulanic acid
- Volunteers
- 100 people
- Sponsor
- University of Catania
Surgical Site Infection (SSI), Spine Surgery
Investigation of the PREVENTIA® Irrigation Solution for Reducing Bacteria in Spinal Surgery With Implants - A Comparative Study
Spinal surgery carries a risk of surgical wound infections (i.e., the entry of bacteria). Despite various preventive measures, such infections continue to occur, particularly in operations involving implants.
- Conditions
- Surgical Site Infection (SSI), Spine Surgery, Surgical Site Infection Prevention
- Trial name
- PROTECT-SPINE (NCT07667036)
- Testing
- Preventia Surgical Solution, 0.9 % NaCl
- Where
- Switzerland
- Volunteers
- 114 people
- Sponsor
- Universität Luzern