Clinical trials: Functional; Anesthesia
Intercostal Nerve Block, Pulmonary Ventilation
EIT Evaluation of Pulmonary Ventilation With Different Ropivacaine Concentrations in Intercostal Nerve Blockade
This study aims to find out how different strengths of the anesthetic drug ropivacaine affect lung breathing function when used in intercostal nerve block (a type of local anesthesia) for breast quadrantectomy surgery.
- Conditions
- Intercostal Nerve Block, Pulmonary Ventilation, Anesthesia, Local, Breast Neoplasms
- Trial name
- EIT (NCT07079436)
- Testing
- 0.25% ropivacaine, 0.375% Ropivacaine, 0.5% Ropivacaine
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Fudan University
Pneumoperitoneum
Influence of Posture and Gas Insufflation on Perioperative Lung Function
Perioperative airway resistance and lung function are evaluated perioperatively in patients, who undergo surgical procedures in different postures and with or without gas insufflation into the peritoneal cavity.
- Trial name
- NCT00948571
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Kliniken Essen-Mitte
Pediatric Retinoblastoma, Retinoblastoma
Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients
The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain…
- Trial name
- NCT03546387
- Testing
- Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V), California Verbal Learning Test, Children's Version, Beery Developmental Test of Visual Motor Integration, 6th edition
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Postoperative Complications
Effect of Daytime Variation on PPCs in Lung Resection Surgery.
The aim of this retrospective study was to evaluate the association between daytime variation in surgery start time and the occurrence of postoperative pulmonary complications (PPCs) and postoperative adverse events (AEs) in…
- Trial name
- NCT05582291
- Where
- China
- Volunteers
- 1,138 people
- Sponsor
- Qianfoshan Hospital
Depressive Disorder
Effects of Ciprofol Anesthesia on Learning and Memory Function and Antidepressant Effects of ECT in Depressive Patients
In this clinical study, propofol was used as the positive control, and a randomized controlled trial design was used to observe the effects of ciprofol anesthesia on learning and memory function and antidepressant efficacy in…
- Trial name
- NCT05266560
- Testing
- ciprofol, Propofol
- Volunteers
- 390 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Disorder of Pacing Function
3D Echocardiographic Assessment of Epicardial Pacing After Cardiopulmonary Bypass.
This study evaluates the usefulness of 3D echocardiography to guide pacemaker therapy in the operating room in cardiac surgical patients. Each patient will serve as his own control, following a paired design.
- Trial name
- NCT02842762
- Testing
- Right ventricular epicardial pacing, cardiac surgery, 3D TEE
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Suzanne Flier, MD
Preoperative, Phentolamine
Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus Surgery
The aim of this study is to evaluate the efficacy of intra-operative phentolamine vs intraoperative esmolol for hypotensive anesthesia in functional endoscopic sinus surgery.
- Conditions
- Preoperative, Phentolamine, Intraoperative, Esmolol
- Trial name
- NCT06620991
- Testing
- Phentolamine, Esmolol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Neurodevelopmental Disorders, Child Behavior Disorders
Impact of General Anesthesia in Childhood on Cognitive Processes
This study aims to evaluate the potential long-term cognitive effects of general anesthesia administered before the age of 4. Specifically, it investigates executive functions-including inhibition, working memory, and cognitive…
- Trial name
- NCT07141797
- Testing
- Executive functions assessment
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Residual Neuromuscular Blockade
Comparison of the ToFscan and TetraGraph During Recovery of Neuromuscular Function in the Post Anesthesia Care Unit
The aim of this investigation is to compare the performance of two quantitative monitors utilized on post-anesthesia recovering patients.
- Trial name
- NCT03920670
- Testing
- TetraGraph (TG), ToFscan (TS)
- Where
- 3 sites in United States, Hungary
- Volunteers
- 120 people
- Sponsor
- Mayo Clinic
Prone Position, Cardiac Output
Effect of Prone Position on Liver Blood Flow and Function
Recent occurrence of significant post-operative liver impairment at Nottingham University Hospitals NHS Trust has prompted investigation into whether interaction between general anaesthesia and prone positioning (lying face down)…
- Conditions
- Prone Position, Cardiac Output, Liver Circulation
- Trial name
- PLiF (NCT01781260)
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Postoperative Pain Management, Open-heart Surgery
Erector Spinae Plane Block and Postoperative Recovery After Open-Heart Surgery
This prospective randomized controlled clinical trial evaluated the effects of bilateral erector spinae plane block (ESPB) on postoperative systemic functions in adult patients undergoing elective open-heart surgery via median…
- Conditions
- Postoperative Pain Management, Open-heart Surgery, Median Sternotomy, Erector Spinae Plane Block
- Trial name
- ESPB-SYSHEART (NCT07259057)
- Testing
- Erector spinae plane block (ESPB), Intravenous Opioid Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Hypotensive Anesthesia
Comparison Between Two Drugs (Propofol and Nitroglycerin as a Hypotensive Agents During Endoscopic Sinus Surgery
Background and Objectives: FESS is a common minimally invasive surgery that requires a clear field to be performed well. Hypotensive anesthesia is one of the most common maneuvers performed to help in keeping the field clear.
- Trial name
- prop (NCT04220281)
- Testing
- Propofol, Nitroglycerin
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia; Reaction, Autonomic Imbalance
Analysis of Autonomic Function During Anesthesia Using Response Surface Model
Anesthesia in the modern age is at least a two-drug process consisting of an opioid and a sedative hypnotic (e.g., fentanyl and propofol in combination, among others).
- Trial name
- NCT03072069
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Central University
Difficult Airway, Anesthesia; Functional
Air-Q Intubating Laryngeal Airway Versus the Laryngeal Mask Airway (LMA)-Proseal
Introduction: The air-QⓇ Intubating Laryngeal Airway (ILA) is a newer supraglottic airway. It is approved for use as a primary airway and as an aid for intubation in situations of anticipated or unanticipated difficult airways.
- Trial name
- NCT01328405
- Testing
- Laryngeal Mask Airway (LMA)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Wisconsin, Madison
Major Abdominal Surgeries
Low-Flow Desflurane Anesthesia and Its Effects on BIS and Postoperative Cognitive Functions
This study investigates the effects of low-flow desflurane anesthesia in adult patients undergoing major abdominal surgery. The researchers will examine whether different low-flow strategies: Cause differences in the Bispectral…
- Trial name
- NCT07212543
- Testing
- Routine anesthesia care (desflurane at different low-flow rates: 0.5, 1.0, 1.5 L/min); no intervention assigned as part of the study.
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Dolunay ARIK
Anesthesia
A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia
The purpose of this study is to understand changes in heart function (how the heart pumps blood) and blood flow in people who receive general anesthesia during surgery.
- Trial name
- NCT05954832
- Testing
- Echocardiography
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Effect of Drugs
Comparative Effect of Hypotensive Anaesthesia on Event Related Potentials, Quantitative Electroencephalograghy
AIM OF THE WORK The aim of this work was to compare the effect of hypotensive anaesthesia using Nitroglycerine versus phentolamine on Event related potentials, quantitative Electroencephalograghy and cognitive function, in…
- Trial name
- NCT04110808
- Testing
- hypotensive anaesthesia using Nitroglycerine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Functional Endoscopic Sinus Surgery
Comparison Between Pregabalin and Magnesium Sulfate in Hypotensive Anaesthesia
Comparison between pregabalin and magnesium sulfate in hypotensive anaethesia
- Trial name
- NCT05442931
- Testing
- Pregabalin 150mg, Magnesium Sulfate, Nitroglycerin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Comparison of Hemodynamics and Respiratory Function Between Ciprofol and Propofol in Elderly Patients Undergoing Non-intubated General Anesthesia
Comparison of Hemodynamics and Respiratory Function Between Ciprofol and Propofol in Elderly Patients Undergoing Non-intubated General Anesthesia
At the initiation of induction for non-intubated general anesthesia, ciprofol or propofol will be administered intravenously at a rate of 10 mL/min.
- Trial name
- NCT07670923
- Testing
- Propofol Injection, Ciprofol Injection
- Where
- China
- Volunteers
- 108 people
- Sponsor
- General Hospital of Ningxia Medical University