Clinical trials: Burn Pain
Chronic Pain Following Thermal Burn Injury
Vitamin D and n-3 Polyunsaturated Fatty Acids (PUFAs) to Prevent Chronic Pain Following Major Thermal Burn Injury
The goal of this study is to develop a safe, effective, and readily available treatment that will prevent chronic pain following Major Thermal Burn Injury (MThBI).
- Trial name
- NCT03313076
- Testing
- Omega-3 fatty acids (fish oil), Vitamin D3 (cholecalciferol)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of North Carolina, Chapel Hill
Burns, Acute Pain
VR-PAT During Home Burn Dressings - Multisite
This study will evaluate the effectiveness of smartphone Virtual Reality Pain Alleviation Therapy (VR-PAT) as a pain distraction tool during repeated at-home burn dressing changes among 100 children (age 6-17 years) with a burn…
- Conditions
- Burns, Acute Pain, Procedural Pain, Injuries
- Trial name
- NCT05673551
- Testing
- VR-PAT
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Nationwide Children's Hospital
Pain, Postoperative, Trauma
Reducing Pain and Anxiety During Dressing Changes After Burn Surgery Using Virtual Reality
Burn injury and its treatment is an intensely painful experience. Most severely injured patients require numerous dressing changes and skin grafting procedures (removing skin from healthy part of the body and moving it to damaged…
- Conditions
- Pain, Postoperative, Trauma, Burns
- Trial name
- BURN-360 (NCT04820400)
- Testing
- Immersive VR Video
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- Sunnybrook Health Sciences Centre
Burn Patients, Pain Management
Comfort Communication Model Intervention for Burn Pain and Pain Anxiety
This single-center, randomized controlled trial will evaluate the effect of a nursing intervention based on the COMFORT Communication Model on procedural pain and burn-specific pain anxiety in adult outpatient burn patients…
- Conditions
- Burn Patients, Pain Management, Nursing Interventions
- Trial name
- NCT07385339
- Testing
- Comfort Communication Model
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Baskent University
Burns
Efficacy and Safety Study of Caldolor (Intravenous Ibuprofen) in Hospitalized Adult and Pediatric Burn Patients
The primary objective of this study of Caldolor administered to hospitalized adult and pediatric burn patients is to determine the efficacy of Caldolor on reducing fever when compared to placebo when administered every 6 hours…
- Trial name
- NCT00606489
- Testing
- Caldolor
- Where
- 5 sites in United States, India
- Volunteers
- 61 people
- Sponsor
- Cumberland Pharmaceuticals
Burn, Hydrotherapy
Virtual Reality, Pain, Clinical Outcomes, Hydrotherapy, Children, Burn
This study aims to evaluate the effect of virtual reality on pain and clinical outcomes during hydrotherapy for children with burn.
- Trial name
- NCT06160518
- Testing
- Virtual reality
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Matrouh University
Burn Injury, Chronic Pain
Immune Mechanisms of Vitamin D to Reduce Chronic Pain After Burn
The goal of this pilot clinical trial is to learn whether vitamin D is able to prevent chronic pain following burn injury and to determine what biological mechanisms are engaged by Vitamin D following burn injury.
- Trial name
- NCT05619289
- Testing
- Ergocalciferol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Burns
ST266 Versus Standard Care In Treating Partial Thickness Burns
The objective of this protocol is to perform a safety and dose-determination efficacy clinical trial in patients having a degree of partial-thickness burn wounds.
- Trial name
- NCT00886470
- Testing
- ST266
- Where
- 14 sites in United States
- Volunteers
- 16 people
- Sponsor
- Noveome Biotherapeutics, formerly Stemnion
Pain, Acute
Virtual Reality Analgesia for Pediatric Burn Survivors
Many children with large severe burns report severe pain during burn wound cleaning. The current study explores whether adjunctive immersive Virtual Reality distraction may help reduce the intensity of pain experienced by…
- Trial name
- NCT03491657
- Testing
- virtual reality distraction (Yes VR), music distraction (No VR)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Burn
Instilled Lidocaine vs Placebo for Pain Management During Vacuum Assisted Closure (VAC) Dressing Changes
Patients will be randomized prospectively to one of two groups. One group will receive 5 mg/kg of 1% lidocaine, and the other will receive .9 normal saline, instilled into their VAC sponge ½ hour prior to VAC dressing change.
- Trial name
- NCT00585325
- Testing
- Instilled 1% Lidocaine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Neuropathic Pain, Pain
Effects of Venlafaxine on Chronic Neuropathic Pain Following Spinal Cord Injury
The purpose of this study is to evaluate the pain-relieving effects of venlafaxine hydrochloride (Effexor) in chronic neuropathic (burning, shock-like, electric) pain after spinal cord injury (SCI).
- Conditions
- Neuropathic Pain, Pain, Spinal Cord Injuries
- Trial name
- NCT00167856
- Testing
- Venalafaxine hydrochloride
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- US Department of Veterans Affairs
Burn; Arm
The Effect of Proprioceptive Neuromuscular Facilitation and Mirror Therapy on Range of Motion, Pain, Functionality, Kinesophobia and Quality of Life in Patients With Upper Extremity Burns
Purpose of the study; The aim of this study was to investigate the effect of two different exercise programs on joint patency, pain, functionality, kinesophobia and quality of life in upper extremity burn patients.
- Trial name
- NCT03997942
- Testing
- Effect of exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Thermal Burns
Continuous Lidocaine Infusion for Management of Perioperative Burn Pain
Thermal injury results in one of the most intense and prolonged forms of pain the body can experience. Opioid narcotics are the most powerful drugs for acute and chronic pain, and their use in the perioperative period has been…
- Trial name
- NCT02059902
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- HealthPartners Institute
Pain, Chronic Pain
Human Factors Analysis in VR for Burn Treatment
A number of studies have shown that virtual reality (VR) can be used to distract patients from pain and anxiety during painful medical procedures for which medication provides inadequate relief.
- Trial name
- NCT00409552
- Testing
- Virtual Reality based distraction, VR with flat projection display, non-interactive video with head display
- Volunteers
- 10 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Second Degree Burns
Heparin for the Treatment of Burn Wound Pain
Pain Associated with partial thickness burns (PTB) is very severe and distressing for the patients.Topical conventional treatment of superficial PTB wounds includes application of polyfax skin ointment plus lignocain gel twice a…
- Trial name
- NCT02497326
- Testing
- Polyfax & Lignocain gel or silvazine cream, Topical Heparin, Tramadol
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- King Edward Medical University
Burns
Intraoperative Small-dose Esketamine Infusion for Pain Control in Burn Patients
This study aim to determine whether a small-dose esketamine infusion can be used for pain control in severe burn patients, and thereby reduce the total intra-operative opioid requirement.
- Trial name
- NCT04682782
- Testing
- Esketamine, Saline
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Burn
Low Dose Ketamine VR Analgesia During Burn Care Procedure
The purpose of the research is to see whether a low dose of ketamine, a medication used to reduce pain, enhances the effectiveness of a virtual reality video game, which is used as a form of distraction from pain during a painful…
- Trial name
- VRK (NCT01889537)
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Pain
Virtual Reality Water Friendly Wound Care
Using virtual reality as a form of distraction during a painful burn wound care procedure in addition to pain medication.
- Trial name
- H2OWC (NCT02646787)
- Testing
- Active Virtual Reality, Passive Virtual Reality
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Washington
Pain, Anxiety
Virtual Reality for Burn Wound Care Pain Control
The investigators propose to study the effects of virtual reality (VR) on patients' pain perception during burn wound care. Such variables include psychiatric diagnosis and standard pain coping (i.e. pain catastophizer vs.
- Trial name
- NCT00663013
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Weill Medical College of Cornell University
Pain, Burns
Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: Trial
Children with burn injuries experience severe pain intensity during medical procedures despite the increasing doses of analgesics.
- Conditions
- Pain, Burns, Child, Anxiety
- Trial name
- DREAM-T (NCT02947243)
- Testing
- VR distraction via Oculus Rift, Morphine
- Where
- Canada
- Sponsor
- St. Justine's Hospital