Clinical trials: sponsored by National Taiwan University Hospital
Chronic Insomnia, Older Adults
Brief Behavioral Therapy for Insomnia (BBTi) in Middle-aged and Older Adults With Chronic Insomnia
This study aims to investigate whether a nurse-led brief behavioral therapy can effectively improve chronic insomnia and sleep health in older adults.
- Conditions
- Chronic Insomnia, Older Adults, Sleep Hygiene, Sleep Health
- Trial name
- NCT06073990
- Testing
- Brief Behavioral Treatment for Insomnia (BBTi)
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- National Cheng-Kung University Hospital
Subarachnoid Aneurysm Hemorrhage
Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Despite its lower incidence rate within the stroke population and tendency to affect younger individuals, SAH carries the highest risk of PSCI.
- Trial name
- NCT07588997
- Testing
- early motor-cognitive integrated training (e-MCIT), Early mobilization
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Taiwan University Hospital
ADHD - Attention Deficit Disorder With Hyperactivity, ADHD - Combined Type
AI-assisted Home-based Intervention for ADHD Children
The goal of this clinical trial is to evaluate the effectiveness of online diary platforms for socio-emotional learning training in children with attention deficit hyperactivity disorder (ADHD).
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, ADHD - Combined Type, ADHD - Inattentive Type
- Trial name
- NCT07922018
- Testing
- Generative artificial intelligence assisted diary platform home-based intervention, Consultations and psychoeducation on child emotional management
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Breast Cancer
Effects of a Mindful Self-Compassion Intervention on Psychological Adjustment in Breast Cancer Survivors
This clinical trial will test a Mindful Self-Compassion (MSC) group program after breast cancer treatment. MSC teaches people to notice difficult feelings and respond to themselves with kindness.
- Trial name
- NCT07911631
- Testing
- Mindful Self-Compassion, Usual care
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- Chung Yuan Christian University
Non-Small Cell Lung Cancer
Effects of a Visual Interactive LINE Chatbot on Self-Management of EGFR-TKI Related Side Effects in Patients With Lung Cancer
This study aims to evaluate a visual interactive LINE chatbot designed to support self-management of treatment-related side effects among patients with advanced lung cancer receiving epidermal growth factor receptor-tyrosine…
- Trial name
- NCT07310589
- Testing
- Visual-Interactive LINE Chatbot
- Volunteers
- 178 people
- Sponsor
- National Taiwan University Hospital
Emergency Department, Revisit
Development, Validation, and Clinical Trial of a Prediction Tool for High-Risk Emergency Department Revisits
Emergency department (ED) visits have grown tremendously in Taiwan over the past few years, reaching approximately 7 million visits in 2019.
- Trial name
- NCT07909096
- Testing
- ED-HIKRS, Usual Care
- Volunteers
- 4,010 people
- Sponsor
- National Taiwan University Hospital
Androgen Levels
Effects of Probiotic Supplementation on Androgen Levels
The goal of this clinical trial is to evaluate the feasibility, safety, and preliminary effects of a probiotic supplement, Bacillus coagulans strain BRCAS-C3, on androgen levels in adult men and women.
- Trial name
- NCT07911813
- Testing
- Bacillus coagulans BRCAS-C3
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Biliary Tract Cancer (BTC)
Daraxonrasib in Asian RAS-mutant Biliary Tract Cancer
The trial will assess the efficacy, safety, and tolerability of daraxonrasib monotherapy in Asian patients with RAS-mutated advanced biliary tract cancer in second-line treatment.
- Trial name
- NCT07908550
- Testing
- Daraxonrasib
- Where
- Taiwan
- Volunteers
- 55 people
- Sponsor
- National Health Research Institutes, Taiwan
Airway Response, Lung Transplant Recipients
Bronchial Response to Exercise After Double Lung Transplantation
This study aims to investigate the airway response to exercise and its association with breathlessness in double lung transplant recipients by comparing responses during 5-minute and 15-minute exercise durations.
- Conditions
- Airway Response, Lung Transplant Recipients, Lung Transplant, Challenge Test
- Trial name
- NCT07035743
- Testing
- Exercise
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Advanced Solid Malignancies
Liposomal Irinotecan Plus Cisplatin in Patients With Advanced or Metastatic Solid Malignancies
Phase I trial, Multiple centers, open-label, non-randomized single-arm study
- Trial name
- ICONIC (NCT07782346)
- Testing
- Liposomal Irinotecan Plus Cisplatin
- Where
- 6 sites in Taiwan
- Volunteers
- 44 people
- Sponsor
- National Health Research Institutes, Taiwan
Hip Fracture Surgeries, High Risk Population of Hip Fractures
A Decision Support Tool for Common Surgical Fixations of Hip Fractures
This study aims to improve how patients, families, and healthcare professionals work together to make important medical decisions, especially in cases involving hip fractures.
- Conditions
- Hip Fracture Surgeries, High Risk Population of Hip Fractures, Decision Surrogate of Hip Fixations
- Trial name
- NCT07909876
- Testing
- IDeA for Hip Fracture, Non-IDeA for hip fracture
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Graves Ophthalmopathy
Hydroxychloroquine in Mild Graves' Orbitopathy
This study is aimed to investigate the effect of hydroxychloroquine in patients with mild Graves' orbitopathy (GO).
- Trial name
- NCT05126147
- Testing
- Hydroxychloroquine
- Where
- 2 sites in Taiwan
- Volunteers
- 108 people
- Sponsor
- National Taiwan University Hospital
Advanced Care Planning (ACP), ELDERLY PEOPLE
Advance Care Planning Impact on the Consistency of Older Adults With Lung Cancer and Their Potential Surrogates Regarding Life-Sustaining Treatment Preferences
This randomized controlled trial examined whether an advance care planning (ACP) tabletop game ("Walking with Wishes") could improve the consistency of life-sustaining treatment preferences between older adults with lung cancer…
- Conditions
- Advanced Care Planning (ACP), ELDERLY PEOPLE, Lung Cancer (NSCLC)
- Trial name
- NCT06616909
- Testing
- ACP GAME, acp manual
- Where
- Taiwan
- Volunteers
- 124 people
- Sponsor
- National Taiwan University Hospital
Medical Visualization, Medical Illustration
Consensus And Norms for Medical Visualization Academic Standards Study - A Modified Delphi Study
The goal of this observational study (modified Delphi consensus study) is to establish an international expert consensus on professional standards for medical visualization in medical visualization experts from from around the…
- Conditions
- Medical Visualization, Medical Illustration, Consensus
- Trial name
- CANVAS (NCT07684703)
- Testing
- Delphi procedure
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cervical Cancer Screening, Cervical Cancer Screening Methods
Ameliorated Pap Tests and Cervical Cancer Screening Participation
The Pap test plays a crucial role in the early detection of cervical cancer. A pilot single-center randomized controlled trial applied the peak-end concept and added a non-painful step at the end of Pap smear screening, aimed to…
- Trial name
- NCT06968871
- Testing
- Modified Pap test
- Where
- 5 sites in Taiwan
- Volunteers
- 850 people
- Sponsor
- National Taiwan University Hospital
the Severity and Duration of Intraoperative Hypotension
Applying HPI in Oral Cancer Surgery
Investigating HPI effect in oral cancer surgery
- Trial name
- NCT07405892
- Testing
- HPI, HPI silence
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
ADHD
Multimodal Biomarkers Predicting Medication-Induced Adverse Effects in Children With ADHD
To build a multimodal model combining neuropsychological, neurophysiological, and metabolomic measures to identify biomarkers predicting MPH-induced adverse effects and their underlying mechanisms, supporting individualized risk…
- Trial name
- NCT07900451
- Testing
- methylphenidate
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Heart Failure With Reduced Ejection Fraction, End Stage Renal Disease on Dialysis
Empagliflozin in Heart Failure With Reduced Ejection Fraction and End Stage Renal Disease
In patients with ESRD, up to 20% of patients suffer from HFrEF, leading to significant CV morbidity and mortality. Several drug classes that provide survival benefits for patients with HFrEF, including SGLT2i, lack data regarding…
- Trial name
- EMPA-RRED (NCT06249932)
- Testing
- Empagliflozin 25 MG
- Where
- 2 sites in Taiwan
- Volunteers
- 95 people
- Sponsor
- National Taiwan University Hospital
Hepato Cellular Carcinoma (HCC), Immune Checkpoint Inhibitor
An Exploratory Study of Single-Dose Neoadjuvant Nivolumab Without Surgical Delay in Patients With Resectable HCC
The goal of this clinical trial is to evaluate whether giving a single dose of Nivolumab (Opdivo®) before curative surgery for patients with resectable liver cancer can activate the body's immune response against the cancer and…
- Conditions
- Hepato Cellular Carcinoma (HCC), Immune Checkpoint Inhibitor, Neoadjuvant Therapy
- Trial name
- NCT07902258
- Testing
- Nivolumab
- Where
- 3 sites in Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
ESRD (End Stage Renal Disease), Dialysis
Laser Acupuncture for Fatigue in Hemodialysis Patients
The goal of this clinical trial is to learn if laser acupuncture (low-level laser therapy) works to treat fatigue and improve quality of life in adults with end-stage renal disease (ESRD) undergoing hemodialysis.
- Conditions
- ESRD (End Stage Renal Disease), Dialysis, Fatigue
- Trial name
- LA-HD-Fatigue (NCT07538310)
- Testing
- Low-Level Laser Acupuncture (LA)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taipei City Hospital
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