Clinical trials: sponsored by University of Michigan
Parkinson Disease
Function-based Accelerated Stimulation Therapy (FAST-therapy) for Freezing of Gait (FOG) After Parkinson's Disease (PD)
Parkinson disease (PD) is a common disorder in which reduced speed of movement results from inadequate brain production of the chemical dopamine.
- Trial name
- NCT05509842
- Testing
- rTMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Violence, Physical, Maltreatment, Child
Evaluating a School-based Social and Material Needs Identification System to Prevent Youth Violence Involvement
The goal of this observational study is to evaluate the effects of Pathways to Potential (P2P) on youth violence involvement in Michigan public K-12 students.
- Trial name
- NCT05986188
- Testing
- Pathways to Potential
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healthy
Multifocal HD-tDCS and Motor Function
The purpose of this study is to understand how the brain controls movement and how Non-invasive Brain Stimulation (NIBS) with a technique called High-density transcranial direct current stimulation (HD-tDCS) can alter brain…
- Trial name
- NCT06561165
- Testing
- Standard HD-tDCS intervention, Multifocal network targeted HD-tDCS intervention, Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Surgery, Pain, Post Operative
Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial
This trial is being completed to compare two commonly used options to treat pain after discharge from surgery. Participants that undergo tonsil removal, gallbladder removal, and knee scope will be eligible to enroll.
- Trial name
- CARES for Kids (NCT06671002)
- Testing
- NSAID, Opioid, Acetaminophen
- Where
- 9 sites in United States
- Volunteers
- 900 people
- Sponsor
- University of Michigan
Heavy Menstrual Bleeding
Delivering tAN to Reduce HMB: The LUNA Study
The LUNA study is a prospective, randomized, double-blind, sham-controlled, decentralized clinical trial in participants with heavy menstrual bleeding of no known structural cause.
- Trial name
- LUNA (NCT07326722)
- Testing
- Sparrow Link
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Spark Biomedical, Inc.
Hormone Care, Mild Depression
Feasibility and Acceptability of Peer Intervention for Improving Mental Health Among People Accessing Hormone Care
The purpose of this study is to test whether the peer support program is acceptable, possible, and can improve mental health among individuals accessing hormone care.
- Conditions
- Hormone Care, Mild Depression, Anxiety
- Trial name
- NCT07354113
- Testing
- Peer support group, Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Head Injury Trauma, Traumatic Brain Injury, Mild
The PIONEER Comparative Effectiveness Study - Project 2
This is a pragmatic, open-label, multicenter, stepped-wedge, Type II hybrid effectiveness-implementation study. It is designed to evaluate both the comparative effectiveness and implementation feasibility of a…
- Trial name
- NCT07829107
- Testing
- Clinical pathway 1: Guidelines plus biomarkers, Clinical guidelines only
- Where
- 6 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- University of Michigan
Type 2 Diabetes
The Breakfast Study
The investigators conducted an acceptability, feasibility, preliminary effectiveness trial of a 4-month, online, very low-carbohydrate breakfast-focused program in 120 adults with type 2 diabetes.
- Trial name
- NCT05986097
- Testing
- Breakfast
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- University of Michigan
Charcot-Marie-Tooth Disease, Type Ia (Disorder), HMSN
Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2
This project includes two projects. One is looking for new genes that cause Charcot Marie Tooth disease (CMT). The other is looking for genes that do not cause CMT, but may modify the symptoms a person has.
- Trial name
- INC-6602 (NCT01193088)
- Where
- 24 sites in United States, Australia and 4 more
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Gingival Recession
Treatment of Gingival Recession Defects Using Platelet-Rich Fibrin With an Allogenic Dermal Matrix
The study aims to test the non-inferiority of an Allogenic Dermal Matrix with Platelet-Rich Fibrin for treatment of gingival recessions in comparison to the Connective Tissue Graft.
- Trial name
- NCT05819515
- Testing
- Tunneled coronally advanced flap
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hypertrophic Cardiomyopathy (HCM)
HCMR Re-Imaging Study
This study aims to learn what might predict heart problems (like sudden death from a fast heart rhythm or heart failure) in people with a genetic condition called hypertrophic cardiomyopathy (HCM).
- Trial name
- NCT07054073
- Testing
- None - observational study
- Where
- 8 sites in United States, United Kingdom
- Volunteers
- 314 people
- Sponsor
- Christopher Kramer
Diabetes
Leveraging Interventions for Needs and Knowledge in Diabetes
Unmet social needs and economic burden persist as key reasons why one-third of people with diabetes have poor disease control. The purpose of this study is to learn whether different tools and types of support may help people…
- Trial name
- LINKD (NCT07676188)
- Testing
- FindHelp, Peer Support, Social Work
- Where
- United States
- Volunteers
- 694 people
- Sponsor
- University of Michigan
Stuttering, Childhood, Stuttering
Network Connectivity and Temporal Processing in Adolescents Who Stutter
The specific purpose of this clinical trial is to compare performance on rhythm perception and production tasks between children who stutter and children who do not stutter.
- Trial name
- NCT05286151
- Testing
- Rhythm discrimination
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hepatocellular Carcinoma
A Pilot Study of Liver Protection Using Prednisone for Patients Receiving Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma
Patients on this study will self administer Prednisone for three days before starting Radiation Therapy (RT) and continue to take 60 mg/day during the first three fractions of RT.
- Trial name
- NCT05901519
- Testing
- Prednisone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan Rogel Cancer Center
Drug Resistant Epilepsy
Goals for Epilepsy Clinic Visits Trial
The purpose of this project is to conduct a trial to assess whether patients that receive a tablet-based waiting room priority communication tool (the "Epilepsy Visit Planner") have improved outcomes compared to patients that do…
- Trial name
- NCT05928598
- Testing
- Survey questionnaires, Epilepsy Visit Planner, Questionnaires for Providers
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of Michigan
Breast Cancer
Study of Ribociclib Administered Concurrently With Postoperative Radiation Therapy in Patients With High-Risk, HR+/HER2- Breast Cancer
The purpose of this research study is to determine the safety, tolerability and dose of Ribociclib when combined with adjuvant radiation in women with high-risk ER+ breast cancer.
- Trial name
- NCT05996107
- Testing
- Ribociclib, Postoperative Radiation Therapy
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- University of Michigan Rogel Cancer Center
Type 2 Diabetes, Insulin Resistance
Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents
This research study collects health-related information and blood samples to better understand how body composition, lifestyle habits, and diet influence meta-inflammatory monocytes (MiMos) in adolescents.
- Conditions
- Type 2 Diabetes, Insulin Resistance, Obesity, Metabolic Disease
- Trial name
- NCT06007404
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Eosinophilic Esophagitis
Patient-Centered Decision Support for Eosinophilic Esophagitis
The study team is conducting this project to learn more about how patients with eosinophilic esophagitis (EoE) like to use and receive educational materials about treatment options and treatment decision making.
- Trial name
- NCT06817213
- Testing
- General education control, Decision support tool
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Michigan
Depression Disorder, Distress, Emotional
Targeted ACT Compared to Supportive Therapy for Depression RCT
Acceptance and Commitment Therapy (ACT) has demonstrated efficacy in reducing depressive symptoms, primarily compared to no treatment or minimal treatment controls.
- Trial name
- NCT06900608
- Testing
- Acceptance and Commitment Therapy, Treatment as usual
- Volunteers
- 52 people
- Sponsor
- Western Michigan University
Breast Carcinoma
CIPN Decision Aid for the Improvement of Chemotherapy Decision Making in Patients With Breast Cancer
This clinical trial studies how well a chemotherapy-induced peripheral neuropathy (CIPN) decision aid works in improving chemotherapy decision making among patients with breast cancer.
- Trial name
- NCT06915168
- Testing
- Informational Intervention, Survey Administration
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan Rogel Cancer Center