Clinical trials: sponsored by Icahn School of Medicine at Mount Sinai
Healthy
Genetic Response to Warfarin in Healthy Subjects
The purpose of this study is to determine the importance of genetic differences on individuals' response to warfarin in a group of healthy subjects.
- Trial name
- NCT01520402
- Testing
- Warfarin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Dry Eye Disease
Systane Ultra Versus Maxidex Versus Saline
This study was to evaluate the healing action on the eye surface of the artificial tear Systane® ULTRA as compared to two other eyedrops: Maxidex and Saline solution.
- Trial name
- NCT01775540
- Testing
- Systane Ultra, Saline solution, Maxidex
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism, Autism Spectrum Disorder
Neural and Behavioral Outcomes of Social Skills Groups in Children With Autism Spectrum Disorder (ASD)
The purpose of this study is to compare two different treatment approaches to social skills groups for high-functioning children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT01190917
- Testing
- Cognitive Behavioral Therapy (CBT), Play Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism, Asperger's Syndrome
Functional Magnetic Resonance Imaging (fMRI) for the Study of Response Inhibition, and Face and Linguistic Processing in Autism
This study investigates face processing, response inhibition and phoneme processing in autistic adults by fMRI.
- Trial name
- NCT00211783
- Testing
- fMRI
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Squamous Cell Carcinoma of the Oral Cavity, Oropharynx
Ex Vivo Multimodal Imaging of Upper Aerodigestive Epithelium
The purpose of this research study is to collect information on whether images made using investigational microscopes can improve researchers' ability to evaluate and distinguish between normal and abnormal areas in tissue…
- Conditions
- Squamous Cell Carcinoma of the Oral Cavity, Oropharynx, Larynx, Hypopharynx
- Trial name
- NCT01321892
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
HIV, HIV Infections
Training Community Members to Deliver HIV Prevention Programs to Urban Youth
This study will examine methods for involving local community members in programs to teach urban youth about how to prevent transmission of HIV.
- Trial name
- NCT00859144
- Testing
- Be Proud! Be Responsible!, Becoming A Responsible Teen (BART), Reducing the Risk
- Where
- United States
- Volunteers
- 901 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Congestive Heart Failure
The Epidemiology of Bleeding and Clotting in Patients Undergoing Heart Transplantation, Coronary Artery Bypass Graft Surgery,or Implantation of Left Ventricular Assist Devices
The purpose of this study is to obtain data or information on how blood clotting factors are activated during open heart surgery.
- Trial name
- NCT01481012
- Where
- 13 sites in United States
- Volunteers
- 94 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Depression, Postpartum, Depression
Using a Preparation and Education Intervention to Reduce Postpartum Depression Among New Mothers (The MADE IT 2 Study)
This study will test an intervention that aims to prevent postpartum depression by providing new mothers with information on and resources for dealing with the disorder.
- Trial name
- NCT00951717
- Testing
- Behavioral education intervention
- Where
- United States
- Volunteers
- 590 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Diabetic Nephropathy
Effect of Sevelamer Carbonate on Oxidative Stress in Patients With Diabetic Nephropathy
The purpose of this study is to determine whether oral sevelamer carbonate binds advanced glycation end products (AGEs) in the gastrointestinal (GI) tract of patients with diabetic nephropathy leading to decrease body AGE load…
- Trial name
- NCT00967629
- Testing
- Sevelamer Carbonate, Calcium Carbonate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Congestive Heart Failure
The Epidemiology of Ventricular Assist Device-Related Infections
Infections often occur after ventricular assist devices (VADs) are placed. These infections can be very serious. The goal of this study is to understand why these infections occur.
- Trial name
- NCT01471795
- Where
- 13 sites in United States
- Volunteers
- 150 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Congenital Heart Disease
Use of AEEG as Predictor of Long-term Motor Outcome in Neonates With Congenital Heart Disease
This study aims to examine performance on a neurological screening test, the Dubowitz, and sleep wake cycles on amplitude integrated electroencephalogram (AEEG) in neonates with congenital heart disease (CHD) as a way to…
- Trial name
- NCT01291797
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hepatitis C, Depressive Disorder, Major
Prevention of Depression in HIV/HCV Co-infected Substance Abuse Patients
The purpose of this study is to determine whether cognitive behavioral therapy (CBT) is effective in the prevention of depression during interferon and ribavirin treatment for hepatitis C infection.
- Conditions
- Hepatitis C, Depressive Disorder, Major, Depressive Disorder, Depression
- Trial name
- NCT00655226
- Testing
- Hepatitis C educational support groups, Cognitive Behavioral Therapy skills based group sessions
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiovascular Disease
Same Day Versus Next Day Discharge: Ambulatory Closure Device Percutaneous Intervention
This is a multi-center trial that will evaluate the safety, feasibility, and cost effectiveness of discharging patients, who have had successful percutaneous coronary intervention (PCI) and deployment of the AngiomaxTM closure…
- Trial name
- ABCD-PCI (NCT01230606)
- Testing
- discharge vs. overnight stay
- Where
- 2 sites in United States
- Volunteers
- 303 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pathological Gambling, Obsessive Compulsive Disorder
Functional Magnetic Resonance Imaging (fMRI) Studies in Pathological Gambling (PG) and Obsessive-Compulsive Disorder (OCD)
This study will explore the brain processes associated with inhibition and reward processing in pathological gamblers and people with obsessive compulsive disorder compared to healthy controls.
- Trial name
- NCT00211822
- Testing
- fMRI
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Uveitic Macular Edema, Intraocular Inflammation
Pilot Study for the Evaluation of Intravitreal Infliximab in the Treatment of Uveitic Macular Edema
The purpose of this study is to determine if intravitreal infliximab is a safe and effective treatment for macular edema secondary to uveitis.
- Trial name
- NCT00958906
- Testing
- Infliximab (intravitreal, 2.0mg/0.05ml)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Type 1 Diabetes Mellitus
Improving Metabolic Control in Diabetic Young Children
: Although intervention or prevention with young children with T1DM may help ameliorate problems or forestall later problems in metabolic control, a number of potential barriers to research have constrained the development of…
- Trial name
- NCT00439985
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Postpartum Depression
Mothers Avoiding Depression Through Empowerment Intervention Trial
Postpartum depressive symptoms are a major health problem that affects hundreds of women annually. The investgators propose to test an intervention to reduce postpartum depressive symptoms and prevent elevated levels of…
- Trial name
- MADE IT (NCT01312883)
- Testing
- Behavioral education intervention
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Relapsed Non-Hodgkin's Lymphoma, Hodgkin's Disease
Host Dendritic Cells in Allograft Patients
The purpose of this study is to assess preliminary efficacy and to determine the safety and feasibility of ex vivo generated dendritic cell (HDC) infusion with and without donor lymphocyte infusion (DLI) after allogeneic stem…
- Conditions
- Relapsed Non-Hodgkin's Lymphoma, Hodgkin's Disease, Multiple Myeloma, Chronic Lymphocytic Lymphoma
- Trial name
- NCT00935597
- Testing
- MSSM/BIIR HDC Vax-001 (Host Dendritic Cells)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Low Back Pain
A Pilot Trial of Intravenous (IV) Pamidronate for Low Back Pain
The purpose of this study is to determine the test dose of pamidronate for treatment of low back pain in terms of safety, tolerability, and pain relief.
- Trial name
- NCT00101790
- Testing
- pamidronate
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Diabetic Macular Edema
Pilot Study for the Evaluation of Intravitreal Infliximab in the Treatment of Diabetic Macular Edema
The purpose of this study is to determine if intravitreal infliximab is a safe and effective treatment for macular edema secondary to diabetes.
- Trial name
- NCT00959725
- Testing
- Infliximab (intravitreal, 2.0mg/0.05ml)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Icahn School of Medicine at Mount Sinai