Clinical trials: Probiotic
Mild Traumatic Brain Injury, Post Traumatic Stress Disorder
Biological Signatures, Probiotic Among Those With mTBI and PTSD
Exaggerated inflammation in the body and brain is thought to play a role in the vulnerability to and aggravation and perpetuation of adverse consequences among those with co-occurring mild TBI (mTBI) and post-traumatic stress…
- Trial name
- NCT02723344
- Testing
- of Lactobacillus reuteri (L. reuteri; DSM 17938), Sunflower and medium chain triglyceride oils
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- VA Office of Research and Development
Lower Urinary Tract Symptoms
Impact of Probiotics on Urinary Symptoms in Spinal Cord Injury SCI and SB
As a collaborative effort between MedStar National Rehabilitation Hospital (NRH)/MedStar Health Research Institute (MHRI), Children's National Medical Center (CNMC) Department of Urology, Children's Research Institute (CRI)…
- Trial name
- NCT02748317
- Testing
- Lactobacillus rhamnosus GG
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Medstar Health Research Institute
Human Microbiome
Effects of Triphala and VSL#3 Probiotic Supplementation on Stool Microbiome Profiles and Inflammation
Normal aging can lead to loss of gut microbial biodiversity which is linked to inflammaging and immunosenescence or the loss of immunocompetence.
- Trial name
- TRIPH2017 (NCT03907501)
- Testing
- Synbiotic, Probiotic
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Antibiotic-associated Diarrhea
Mechanisms of Preventing Antibiotic-Associated Diarrhea and the Role for Probiotics
The focus of the study is to better understand the mechanisms causing antibiotic-associated diarrhea (AAD) and how probiotics may prevent some of the iatrogenic effects of antibiotic medications.
- Trial name
- YOBIOTIC (NCT03755765)
- Testing
- Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet, BB-12, Control
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Probiotics
Gastric Acid Suppression and Probiotic Colonization
Probiotics are over-the-counter dietary products with microorganisms that are generally consumed for health benefit. However, the durability of these microorganisms is unclear, particularly when they pass through the highly…
- Trial name
- PR (NCT03327051)
- Testing
- Omeprazole, VSL #3
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Stanford University
Respiratory Tract Infections, Gastrointestinal Diseases
Probiotics and Infections in Conscripts in Military Service
The aim was to study whether probiotic intervention has an impact on seasonal occurrence of upper respiratory and gastrointestinal infections in two different conscript groups.
- Conditions
- Respiratory Tract Infections, Gastrointestinal Diseases, Asthma Exacerbations
- Trial name
- NCT01651195
- Testing
- Probiotic
- Where
- 2 sites in Finland
- Volunteers
- 983 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Children
Safety of BB-12 Supplemented Strawberry Yogurt For Healthy Children
The investigators believe a readily available drink containing a high dose of probiotics has the potential to improve compliance through many of these mechanisms.
- Trial name
- NCT01652287
- Testing
- BB-12 supplemented strawberry yogurt, Strawberry flavored yogurt
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Alcoholic Liver Disease
Effect of Probiotics on Gut-Liver Axis of Alcoholic Liver Disease
Background/Aims: The investigators explored the therapeutic effects of probiotics in patients with AH. Methods: Between September 2010 and April 2012, the investigators conducted a 7-day, double-controlled, randomized…
- Trial name
- EPALD (NCT01501162)
- Testing
- hepatitis, alcohol, probiotics
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Anorexia Nervosa, Constipation
The Role of Lactobacillus Reuteri in Children and Adolescents With Anorexia Nervosa
The aim of this study is to investigate whether Lactobacillus reuteri could have a beneficial role in treatment of children and adolescents with Anorexia nervosa who develop motility disorder due to the malnutrition regarding the…
- Trial name
- NCT02004288
- Testing
- Lactobacillus reuteri Protectis DSM17938
- Where
- Croatia
- Volunteers
- 31 people
- Sponsor
- BioGaia AB
Colic, Inflammation
Effect of Lactobacillus Rhamnosus GG (LGG) on Infant Colic
This study will compare 2 currently marketed formulas in healthy full term babies: Nutramigen A+ (a hypoallergenic formula) and Nutramigen-Enflora (hypoallergenic formula with Lactobacillus GG (LGG)) during 3 months of formula…
- Trial name
- LGG (NCT01279265)
- Testing
- Nutramigen with Enflora, Nutramigen A+
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Common Cold
Effect of Probiotic on Rhinovirus Induced Colds
This is a randomized, double-blind placebo controlled trial to evaluate the effect of a probiotic (Bl-04) on the occurrence of rhinovirus-associated common cold illness in the experimental rhinovirus challenge model.
- Trial name
- MK EPRIC (NCT02679807)
- Testing
- Bifidobacterium animalis subsp. lactis Bl-04, sucrose
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Recurrent Urinary Tract Infection in Adult Women
Evaluating the Effect of the Probiotic on Recurrent Urinary Tract Infection in Adult Women
Urinary tract infections (UTIs) are the most common bacterial infections in women, with about 50% of women experiencing at least one UTI in their lifetime.
- Trial name
- NCT03366077
- Testing
- Probiotic
- Where
- Sweden
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Healthy
Safety of Lactobacillus Reuteri in Healthy Children Aged 2-24 Months
Phase I double blinded randomized trial of the safety and tolerability of Lactobacillus reuteri DSM 17938 given for five successive days in healthy children.
- Trial name
- PRIDEC Peru (NCT02460575)
- Testing
- Lactobacillus reuteri 17938
- Where
- Peru
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tulane University School of Medicine
Signs and Symptoms, Digestive
Fermented Milk Drink on Human Intestinal Microflora
Fermented milk is a popular drink. Recent studies revealed that some fermented milk containing some strains of lactic acid bacteria have health-promoting effects through improvement of the intestinal microflora and modulation of…
- Trial name
- NCT00822328
- Testing
- Yakult®300, Lactobacillus casei strain Shirota
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cheng Hsin Rehabilitation Medical Center
Celiac Disease
Desensitising Celiac Disease Patients With the Human Hookworm
We have established that the hookworm Necator americanus (Na) dramatically alters the local and systemic immune landscape of the infected human host.
- Trial name
- NaCeD (NCT01661933)
- Testing
- Necator americanus
- Where
- Australia
- Volunteers
- 12 people
- Sponsor
- The Prince Charles Hospital
Clostridium Difficile
Early FMT for C.Difficile
Clostridium difficile infection (CDI) has increased worldwide in both frequency and severity. It is the leading cause of hospital acquired infection in developed countries and has been associated with at least 14,000 deaths per…
- Trial name
- NCT02465463
- Testing
- Fecal microbiota transplant (FMT), flexible sigmoidoscopy
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Emory University
Diverticulitis
Asacol Acute Diverticulitis(DIVA)Study
The purpose of this study is to determine whether Asacol® 2.4 g/day (400 mg Mesalamine) is safe and effective in the treatment of diverticulitis.
- Trial name
- NCT00554099
- Testing
- Mesalamine, Probiotic, Dietary Advice
- Where
- 36 sites in United States
- Volunteers
- 117 people
- Sponsor
- Warner Chilcott
Insulin Sensitivity
Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim 1)
The purpose of this study is to determine insulin sensitivity in individuals that are lean normal glucose tolerant subjects after consumption of a normal low fat diet and after a high fat diet and to explore the effects of high…
- Trial name
- MicroB1 (NCT02124759)
- Testing
- Sevelamer, Synbiotic, Maltodextrin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
HIV Infections, Immunological Abnormality
The Role of Probiotics in HIV Patients With Immunological Non-Responder
This study will address HIV patients who are on antiretroviral treatment (ART) and experiencing immunological failure. The cause of immunological failure in HIV patients could be due to several factors such as age, gender…
- Trial name
- PIONIR (NCT03568812)
- Testing
- Rillus®
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Indonesia
Healthy Adults
Dietary Supplement With and Without a Probiotic and/or Antibiotic
Complex oligosaccharides can alter the gut microbiome by aiding in the growth of certain organisms, and possibly, inhibiting others. The synergy with a probiotic may enhance gastrointestinal colonization.
- Trial name
- NCT05141903
- Testing
- Antibiotic, HMO Concentrate, Probiotic
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Prolacta Bioscience