Clinical trials: Probiotic
Group B Streptococcus Carrier in Childbirth, Gastrointestinal Symptoms
The Efficacy of Probiotics to Reduce Antepartum Group B Streptococcus Colonization.
This study is a randomized double blind, placebo controlled trial to determine the efficacy of an oral probiotic in reducing antenatal Group B Streptococcus colonization.
- Trial name
- NCT03696953
- Testing
- Florajen3
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Marquette University
Osteopenia, Osteoporosis
Food Trial Evaluating Fecal Abundance of SBD111 With Once-Daily Versus Twice-Daily Administration in Healthy Adults
The purpose of this study is to determine whether a modified formulation and daily intake schedule of SBD111 results in similar levels of probiotic microbes in the gut compared with the currently used formulation.
- Conditions
- Osteopenia, Osteoporosis, Menopause Related Conditions, Probiotic Intervention
- Trial name
- NCT07538167
- Testing
- SBD111(current formulation), SBD111 (new formulation)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Solarea Bio, Inc
Group B Strep Infection
Group B Streptococcus Response After Probiotic Exposure
This is an open-label randomized control trial and feasibility study designed to determine the feasibility of a larger RCT in our setting that would examine prenatal probiotic use in Group B Strep (GBS) positive pregnant women at…
- Trial name
- GRAPE (NCT04721912)
- Testing
- Probiotic dietary supplement
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of New Mexico
Healthy
Evaluation of Dose-effect of a New Fermented Food in Healthy Adults
The aim of the study is to assess the safety and tolerance of a new fermented food versus a control product in healthy adults during the 4-week consumption period.
- Trial name
- NCT01108419
- Testing
- Fermented dairy product, milk-based non-fermented dairy product
- Where
- Germany
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Overweight
Probiotics for Weight Loss
This study will investigate a compound of probiotics and prebiotics in females and males with overweight with the aim to evaluate the effect on weight and metabolic markers.
- Trial name
- NCT04897698
- Testing
- LB001
- Where
- Sweden
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Healthy, Stress, Psychological
Stress & Anxiety Dampening Effects of a Probiotic Supplement Compared to Placebo in Healthy Subjects
The aim of this study is to assess whether a 5 week intake of a probiotic (Lpc-37) can modulate stress and anxiety experienced by healthy subjects during and after an acute stressor compared to placebo.
- Trial name
- NCT03494725
- Testing
- Lpc-37
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Daacro
CARRIER STATE
Efficacy of a Probiotic or Fecal Microbiota Transplantation (FMT) on the Eradication of Rectal Multidrug-resistant Gram-negative Bacilli (MDR-GNB) Carriage (PROFTMDECOL)
The working hypothesis is that in patients who are rectal carriers of MDR-GNB (Multi drug-resistant gram negative bacilli), the rate and speed of eradication of the carrier status obtained with NAA regimens are insufficient and…
- Trial name
- PROFTMDECOL (NCT04431934)
- Testing
- PROBIOTIC, FMT REGIMEN
- Where
- Spain
- Volunteers
- 437 people
- Sponsor
- Hospital Clinic of Barcelona
Healthy Individuals
Effects of BLa80 and LRa05 on the Gut Microbiota Metabolite Profile of Healthy Individuals
Gut microbiota play a key role in polyphenol metabolism, participating in the breakdown of dietary components and producing various small molecule metabolites that affect human health.
- Trial name
- NCT07287306
- Testing
- BLa80, LRa05
- Where
- China
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Atopic Dermatitis
Efficacy of Fermented Rice Flour for the Treatment of Atopic Dermatitis
This Study Evaluate the efficacy of the subministration of fermented rice flour (7 g/day) on the clinical course of patients with moderate or severe Atopic Dermatitis, in terms of a reduction in the SCORAD score, during the study…
- Trial name
- NCT03157284
- Testing
- Rice Flour
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- Heinz Italia SpA
Periodontitis, Probiotics
Effects of Probiotic Therapy in the Treatment of Periodontitis.
The aim of this study is to evaluate the effect of the probiotic therapy as an adjunct to non-surgical periodontal treatment in patients diagnosed with Generalized Chronic Periodontitis.
- Trial name
- NCT03408548
- Testing
- Scaling root planning, Probiotic
- Where
- Brazil
- Volunteers
- 41 people
- Sponsor
- University of Sao Paulo
Microbial Colonization
Effect of Probiotics on Infant's Fecal Microbiota Composition
Randomized clinical trial to evaluate the effect of two probiotic strains which belong to Bifidobacterium Longum and Pediococcus pentosaceus species on fecal microbiota composition in healthy infants.
- Trial name
- BABYCARE (NCT05524649)
- Testing
- Food Supplement 1, Food Supplement 2
- Where
- 2 sites in Mexico, Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Blood Pressure, Body Composition, Immune Function
Evaluating the Effects of a Synbiotic Versus Probiotic or Placebo on Gut Microbiota and Cardiometabolic Health: A Randomized Double-Blind Placebo Controlled Trial
Accordingly, the purpose of this study is to evaluate the efficacy of 1) supplementation with Synbiotic (Plexus® Triplex), 2) commercially-available Probiotic, or 3) placebo control over 30 days on the gut microbiome…
- Trial name
- GUTRCT (NCT06544915)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Osteoarthritis of Multiple Joints
Probiotic for Osteoarthritis
The gut microbiome appears to be a significant contributor to musculoskeletal health and disease. Microbiome composition and its functional implications have been associated with prevention of bone loss and/or reducing fracture…
- Trial name
- NCT03985709
- Testing
- Probiotic product
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Osteoarthritis, Knee
Probiotic Supplements in Osteoarthritis
The current study aims to evaluate the effectiveness of adding probiotics to the standard of care in improving OA patient-related outcomes such as pain, stiffness, and physical activity.
- Trial name
- NCT07364578
- Testing
- Probiotic Formula, Control
- Where
- Egypt
- Volunteers
- 146 people
- Sponsor
- Beni-Suef University
Overweight and Obesity, Prediabetes
Effects of Biofunctional Orange Juice on Cardiometabolic Risk Markers
The effects of orange juice enriched with vitamin D3 and encapsulated probiotics (Lacticaseibacillus casei Shirota and Lacticaseibacillus rhamnosus GG) compared to conventional orange juice on several cardiometabolic and…
- Conditions
- Overweight and Obesity, Prediabetes, Hypertension, Dyslipidemias
- Trial name
- NCT06114576
- Testing
- Orange juice enriched with vitamin D3 and encapsulated probiotics, Conventional orange juice
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Agricultural University of Athens
Oral Microbiome Health
Efficacy of VRx MyBiotics Oral Lozenges
This study will test the efficacy of Viome's VRx MyBiotics Oral Lozenges at improving the oral microbiome.
- Trial name
- NCT05972330
- Testing
- VRx MyBiotics Oral Lozenges
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Viome
Gastroenteritis
Impact of Emergency Department Probiotic (LGG) Treatment of Pediatric Gastroenteritis
The investigators will study the efficacy and side effect profile of LGG, a probiotic, in pediatric patients with acute gastroenteritis.
- Trial name
- NCT01773967
- Testing
- LGG, micro-crystalline cellulose
- Where
- 10 sites in United States
- Volunteers
- 971 people
- Sponsor
- Washington University School of Medicine
Vitamin D Deficiency
Evaluation Of The Effect Of L. Casei DG® On Vitamin D Absorption In Patients Under Vitamin D Supplementation.
Vitamin D deficiency is one of the most underdiagnosed and undertreated medical condition worldwide . The microbiome and vitamin D deeply influence each other and the immune system in many different ways.
- Trial name
- NCT05394207
- Testing
- L. casei DG® (Lactobacillus paracasei CNCM I-1572)
- Where
- United Arab Emirates
- Volunteers
- 46 people
- Sponsor
- SOFAR S.p.A.
Irritable Bowel Syndrome
Probiotics in the Treatment of Irritable Bowel Syndrome
Evidence have shown benefits of gut flora modulation in treatment of irritable bowel syndrome (IBS), but few reports are available on the effects of multistrain probiotics and there are few reports available in this regard from…
- Trial name
- NCT01837472
- Testing
- Probiotic
- Where
- Iran
- Volunteers
- 132 people
- Sponsor
- Isfahan University of Medical Sciences
Healthy Adults
Effect of Probiotic on the Gut Microbiota of Healthy Volunteers
The goal of this placebo-controlled randomized trial is to test the effect of intervention with Bifidobacterium animalis subsp. lactis BLa80 on the composition of the gut microbiota of healthy volunteers.
- Trial name
- NCT06103253
- Testing
- a Bla80 group
- Where
- China
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
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