Clinical trials: in Pakistan
Inherited Eye Disease
Clinical and Molecular Studies in Families With Inherited Eye Disease
Background: Genes are the basic units of heredity. When genes are changed, certain cells don t work like they should. Researchers want to try to better understand the genetic conditions that are linked with inherited eye…
- Trial name
- NCT02771236
- Where
- 10 sites in United States, China and 6 more
- Volunteers
- 5,000 people
- Sponsor
- National Eye Institute (NEI)
Hypertension, Primary Hypertension
Text Message Support to Help Adults With Newly Diagnosed High Blood Pressure Control Their Blood Pressure in Primary Care Clinics in Germany and Pakistan
The goal of this clinical trial is to learn if text messages can help adults with newly diagnosed high blood pressure (hypertension) bring their blood pressure under control.
- Trial name
- NCT07878728
- Testing
- mHealth Text Message Program, Usual Care
- Where
- Pakistan
- Volunteers
- 1,295 people
- Sponsor
- GIFT University
Hearing Disorder
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan
Objective: One objective of this study is to genetically map and identify mutated genes for human hereditary hearing loss. A second objective is to study the function of these genes in the auditory system using mouse models.
- Trial name
- NCT00341874
- Where
- Pakistan
- Volunteers
- 18,009 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Identification of Residual Cholesteatoma After Microscopic Mastoidectomy With and Without Check Endocscopy
Comparison of Outcomes of Microscopic Mastoidectomy With and Without Check Endoscopy
PROJECT SUMMARY Cholesteatoma is a serious otological condition that remains a serious problem and poses a great challenge to otolaryngologists around the globe.
- Trial name
- NCT07896200
- Testing
- Mastoidectomy with and without check endoscopy for cholesteatoma surgery
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Sheikh Zayed Federal Postgraduate Medical Institute
Perforated Duodenal Ulcer
Comparison of Open vs Laparoscopic Repair of Perforated Duodenal Ulcer
This randomized controlled trial aims to compare open and laparoscopic repair of perforated duodenal ulcer in terms of postoperative outcomes.
- Trial name
- NCT07893951
- Testing
- Laparoscopic Repair of Perforated Duodenal Ulcer, Open Repair of Perforated Duodenal Ulcer
- Where
- Pakistan
- Volunteers
- 134 people
- Sponsor
- Allied Hospital Faisalabad
Recurrent Bacterial Vaginosis
Probiotics as an Adjunct to Antibiotics for Recurrent Bacterial Vaginosis
This randomized clinical trial aims to compare the recurrence of bacterial vaginosis (BV) in women receiving probiotics alongside antibiotic treatment versus women receiving antibiotic treatment alone.
- Trial name
- NCT07893782
- Testing
- Probiotic Combination Cap/Tab
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Nishtar Medical University
Focus of the Study is Smoking Cessation and Prevention, Smoking Prevention
Effectiveness Of Project EX: A Classroom-Based Smoking Prevention And Cessation Intervention Program
The goal of this intervention is to learn if Project EX helps in prevention and cessation of smoking in adolescents. The main question it aims to answer is: 1.
- Trial name
- NCT07895784
- Testing
- Project EX
- Where
- Pakistan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Karachi
Healthy Participants
Comparative Study of Effects of Neuromuscular Warmup vs Conventional Warmup in Recreational Gym Population
Impaired balance or insufficient strength may increase the risk of musculoskeletal injuries among recreational enthusiasts. Warm-up protocols are an essential component of exercise preparation, aiming to enhance performance and…
- Trial name
- NMWU YBT CMJ (NCT07340021)
- Testing
- NM Warm-up, Conventional Warm-up
- Where
- 2 sites in Pakistan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Lahore University of Biological and Applied Sciences
Ventral Hernia Repair, Hernia Abdominal Wall
Onlay vs. Sublay Mesh Hernioplasty for Primary Ventral Hernia
This randomized controlled trial will compare the surgical outcomes of onlay mesh hernioplasty versus sublay mesh hernioplasty in patients with primary ventral wall hernias.
- Trial name
- NCT07896278
- Testing
- Onlay Mesh Hernioplasty, Sublay Mesh Hernioplasty
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Provincial Headquarter Teaching Hospital Gilgit
Rotator Cuff Tendinopathy
Comparative Effects of Cyriax Approach With and Without Mobilization With Movement in Shoulder Restriction With Rotator Cuff Tendinopathy
This randomized clinical trial compares the effects of the Cyriax approach (deep transverse friction massage) with and without Mulligan Mobilization with Movement (MWM) on pain, range of motion and disability in patients with…
- Trial name
- NCT07895810
- Testing
- Cyriax Approach with Mobilization with movement, Cyriax Approach without Mobilization with Movement
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- University of Management and Technology Lahore
Tuberculosis (TB)
Optimal Treatment Duration for Radiographically Apparent, Bacteriologically Unconfirmed TB, Identified Through Active Case Finding (RADIO-TB Trial)
People living in high TB burden communities who undergo active case finding for TB may have chest X-ray changes suggestive of TB but their sputum test can be negative for the TB bacteria or they are unable to provide a sputum…
- Trial name
- RADIO-TB (NCT07163143)
- Testing
- Isoniazid (H), Rifampicin (R), Pyrazinamide (Z)
- Where
- 4 sites in Pakistan, South Africa and 1 more
- Volunteers
- 784 people
- Sponsor
- University College, London
Knee Osteoarthritis
Effects of Low-Load Blood Flow Restriction Resistance Training With and Without Hip Abductor Strengthening in Patients With Knee Osteoarthritis.(BFR)
This study aims to compare the effects of low-load Blood Flow Restriction (BFR) resistance training with and without hip abductor strengthening in patients with knee osteoarthritis.
- Trial name
- yes (NCT07892144)
- Testing
- Hip Abductor Strength Training followed by Low-Load BFR Resistance Training, Low-Load Blood Flow Restriction (BFR) Resistance Training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- University of Management and Technology Lahore
Neonatal Respiratory Distress Syndrome
Heated, Humidified High-flow Nasal (HHHFN) Cannula vs Nasal Continuous Positive Airway Pressure in Respiratory Distress in Premature Neonates
Newborn babies who have difficulty breathing may need breathing support to help them receive enough oxygen. Two commonly used methods are heated, humidified high-flow nasal cannula (HHFNC), which delivers warmed, moist air and…
- Trial name
- NCT07891494
- Testing
- Heated Humidified High-Flow Nasal Cannula therapy, nCPAP
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Gingivitis
Effectiveness of Oil Pulling Using Oils in Comparison With Mouthwash for Gingivitis
The goal of this clinical trial is to learn if daily oil pulling with coconut oil or sesame oil works as effectively as a standard mouthwash to treat gum swelling and redness (gingivitis) in adults aged 18 to 55 years.
- Trial name
- NCT07892235
- Testing
- virgin coconut oil (VCO), Sesame Oil, 0.2% Chlorhexidine Digluconate Mouthwash
- Where
- Pakistan
- Volunteers
- 45 people
- Sponsor
- Bahria University
Knee Arthritis Osteoarthritis, Neuromuscular Adaptations
Effects Of Sensor Assisted Neuro-muscular Exercise Vs Electrical Stimulation On Bio-mechnical And Functional Parameters In Grade II And III Knee Osteoarthritis.
This two-arm randomized controlled trial compared Sensory-Assisted Neuromuscular Exercise (Group A) with Electrical Stimulation (Group B) in 40 adults aged 40-65 with Kellgren-Lawrence Grade II-III knee osteoarthritis, recruited…
- Trial name
- NCT07891351
- Testing
- Sensory-Assisted Neuromuscular Exercise, Electrical stimulation
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Ziauddin University
Computer Vision Syndrome
Comparative Effects of Exercises on Pain, Cervical Proprioception, Neck Disability and Visual Performance in Patients With Computer Vision Syndrome.
This study aims to compare the effectiveness of cervical sensorimotor training and oculomotor training in patients with Computer Vision Syndrome (CVS).
- Trial name
- NCT07892040
- Testing
- Cervical Sensorimotor Training, Occulomotor Training
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- University of Management and Technology Lahore
Generalised Anxiety Disorder, Anxiety
Effectiveness of Single-Session Acceptance and Commitment Therapy for Generalized Anxiety Symptoms.
This study examined whether a single 120-minute, therapist-led Acceptance and Commitment Therapy (SS-ACT) session, delivered individually and face-to-face in Urdu, was associated with reduced generalized anxiety symptoms among…
- Trial name
- SS-ACT (NCT07892768)
- Testing
- Single-Session Acceptance and Commitment Therapy (SS-ACT)
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- GIFT University
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
PRISM Trial: Partial Breast Versus Whole Breast Radiation in Early Breast Cancer
Breast-conserving surgery followed by radiotherapy is a standard treatment for women with early-stage breast cancer. Whole breast irradiation (WBI) is the current standard approach, but partial breast irradiation (PBI), which…
- Trial name
- PRISM (NCT07811635)
- Testing
- Ultra-Hypofractionated Partial Breast Irradiation, Ultra-Hypofractionated Whole Breast Irradiation
- Where
- 3 sites in Pakistan, Saudi Arabia and 1 more
- Volunteers
- 100 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Back Pain
Comparative Effects of Soft Tissue Mobilization and Pressure Therapy With and Without Dynamic Cupping on on Pain and Disability in Patients With Thoracic Back Pain.
This study aims to compare the sequential effects of Instrument-Assisted Soft Tissue Mobilization (IASTM) and Transverse Oscillatory Pressure (TOP), with and without Directional Dynamic Cupping, in patients with thoracic back…
- Trial name
- NCT07892066
- Testing
- Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP), Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP) and Directional dynamic cupping
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- University of Management and Technology Lahore
Text Neck Syndrome
Effects of Progressive Neck Motor Control Exercises With and Without Conventional Therapy in Text Neck Syndrome.(PNMCE-TNS)
This study aims to compare the effects of Progressive Neck Motor Control Exercises (PNMCE) with and without conventional physiotherapy in patients with Text Neck Syndrome.
- Trial name
- Yes (NCT07892131)
- Testing
- Progressive Neck Motor Control Exercises, Progressive Neck Motor Control Exercises and Conventional Therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- University of Management and Technology Lahore
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