Back PainNCT07892066

Comparative Effects of Soft Tissue Mobilization and Pressure Therapy With and Without Dynamic Cupping on on Pain and Disability in Patients With Thoracic Back Pain.

A study testing Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP) and Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP) and Directional dynamic cupping in people with Back Pain, run by University of Management and Technology Lahore at 1 site in Pakistan.

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Sites and contacts

Official record

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Trial summary

Who is it for?: Ages 25 to 45 years
Conditions the study is for: Back Pain
What is being tested?: Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP) and Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP) and Directional dynamic cupping
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 64 participants
Where: 1 sitePakistan
Study dates: 20 Oct 2026to 31 Dec 2026
Phase: Interventional

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 25 to 45 years
All sexes
No healthy volunteers
Adult

Who may be able to join

Non-specific chronic thoracic back pain patients aged between 25 to 45 Both genders. Mild to moderate thoracic back pain with NPRS pain score value of between 3/10 6/10. Pain from at least past three months (12 weeks). Pain localized to thoracic region T1-T12, no radiating pain Willing to provide informed consent and attend all sessions

Who cannot join

Pathological conditions or diagnosed with disk herniation, spinal stenosis, spondylolisthesis, and spondylitis and other medical illnesses such as tumor, lungs disease, and visceral disease or any other red flag condition Referred pain: cervical/lumbar radiculopathy History of cardio-respiratory disease, thoracic surgery, or ribs fracture fixation surgery <6 months Bleeding disorder/anticoagulant use, skin infection, hypersensitivity at treatment area Pregnancy, BMI >35.

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Pakistan1 site

University of Management & Technology
Lahore, Punjab Province, 54000

Other trials in Pakistan

About this study

Official title: Comparison of Sequential Effects of Instrument Assisted Soft Tissue Mobilization and Transverse Oscillatory Pressure With and Without Directional Dynamic Cupping on Pain and Disability in Patients With Thoracic Back Pain.

This study aims to compare the sequential effects of Instrument-Assisted Soft Tissue Mobilization (IASTM) and Transverse Oscillatory Pressure (TOP), with and without Directional Dynamic Cupping, in patients with thoracic back pain. The study will evaluate the effectiveness of these treatment approaches in reducing pain, improving functional ability, and minimizing disability during daily activities.

Conditions: Back Pain
Being tested: Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP), Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP) and Directional dynamic cupping
Keywords: Instrument-assisted soft tissue mobilization, Manual therapy, Functional disability, Directional dynamic cupping, Transverse oscillatory pressure
Medical subject headings: Back Pain

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP)Other
Participants will receive Instrument-Assisted Soft Tissue Mobilization (IASTM) and Transverse Oscillatory Pressure (TOP) in sitting or prone positions, combined with alternating 10-second resisted isometric trunk flexion-extension contractions. Conventional therapy includes a hot pack for 10 minutes and muscle stretching (10 repetitions, 30-second hold each).
Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP) and Directional dynamic cuppingOther
Participants will receive a moist hot pack over the thoracic region for 10-15 minutes, followed by IASTM using the Graston tool for 5-8 minutes.
Transverse Oscillatory Pressure (TOP) will be applied for 3-5 minutes per affected segment, according to patient tolerance.
Directional Dynamic Cupping will then be performed over the thoracic paraspinal muscles for 5-10 minutes with controlled suction and gliding movements.

Study groups in NCT07892066
Study group	Role	What they receive
Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP)	Active comparator	Not described Receives: Other: Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP)
Instrument assisted soft tissue, Transvers oscillatory pressure and Directional dynamic cupping	Experimental	Not described Receives: Other: Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP) and Directional dynamic cupping

What is being measured

The primary outcome is the main question the study is designed to answer.

Numerical Pain Rating Scale
The 11-point numeric with 0 representing No pain, 1-3 representing Mild Pain (nagging, annoying, interfering little with ADLs), 4-6 representing Moderate Pains (interferes significantly with ADLs), 7-10 representing Sever Pain (disabling, unable to perform ADLs).
Measured: Baseline , after 2 weeks and 4 weeks post treatment
FUNCTION RATING INDEX
The Functional Rating Index (FRI) consists of 10 items: pain intensity, pain frequency, sleep, personal care, travel, work, leisure activities, lifting, walking, and standing. Two items assess pain characteristics, while eight assess spinal functional limitations in daily activities. Each item is scored from 0 (no pain/full function) to 4 (maximum pain/total disability), with higher scores indicating greater disability.
Measured: Baseline , after 2 weeks and 4 weeks post treatment
BUBBLE INCLINOMETER
Lumbar range of motion (ROM) will be measured in standing using bubble inclinometers, with S1 and T12 as reference points for flexion and extension, and T12 for lateral flexion.
Two inclinometers will assess forward flexion, while one will assess extension and lateral flexion; actual flexion and extension ROM will be calculated by subtracting the lower inclinometer reading from the upper reading.
Measured: Baseline , after 2 weeks and 4 weeks post treatment

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

20 Oct 202631 Dec 2026

First posted23 Oct 2026
Study start20 Oct 2026 (estimated)
Primary completion31 Dec 2026 (estimated)
Study completion31 Dec 2026 (estimated)

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for Back PainStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Single blind
Who is masked: Outcomes assessor
Enrolment: 64 participants (estimated)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07892066
Sponsor's protocol ID: RE-166-2026
Status last verified: Oct 2026
First submitted: 17 Oct 2026
Last updated: 23 Oct 2026
Results posted: No
Data monitoring committee: Yes
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: Yes: The result data collected de-identified individual participant data will be shared.

Interested in taking part?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See sites and contacts

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