Clinical trials: Veteran
Major Depressive Disorder
VA Augmentation and Switching Treatments for Improving Depression Outcomes
The overall purpose is to determine research based 'next-steps' for outpatients with major depressive disorder who have not had satisfactory outcomes to standard 'first-step' treatments.
- Trial name
- VAST-D (NCT01421342)
- Testing
- Switching: Bupropion-SR, Augmenting: Antidepressant + Bupropion-SR, Augmenting: Antidepressant + Aripiprazole
- Where
- 35 sites in United States
- Volunteers
- 1,522 people
- Sponsor
- VA Office of Research and Development
Heart Failure
Veterans Intensive Personalized Treatment in Heart Failure
In the VIP (Veterans Intensive Personalized) Treatment in Heart Failure Study we will assess 2 novel interventions to enhance adherence and improve quality of life in veterans with heart failure.
- Trial name
- VIP (NCT01404988)
- Testing
- Telephone-Delivered BI, Telephone-Delivered BEI, Telephone-Delivered API
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- US Department of Veterans Affairs
Drinking, Alcohol
Improving Outcomes for Emergency Department Patients With Alcohol Problems
The investigators will conduct a study to examine the impact of an alcohol peer-mentor intervention starting in the emergency department (ED) combined with 6 peer booster sessions to reduce hazardous drinking and facilitate…
- Trial name
- Project GOAL (NCT03536546)
- Testing
- Alcohol Peer Mentor Intervention, Brief Advice
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- VA Office of Research and Development
Prediabetes
INcreasing Veteran EngagemeNT to Prevent Diabetes (INVENT)
This study will evaluate a VA MyHealtheVet Secure Messaging intervention that uses different intervention messaging strategies designed to increase engagement in behaviors to prevent type 2 diabetes.
- Trial name
- INVENT (NCT03403231)
- Testing
- INVENT Secure Messaging Intervention
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Upper Limb Amputation
Brasthesis Prosthetic Harness for Women Veterans With Upper Limb Amputations
This project tests Brasthesis, a new product for women Veterans with upper limb loss. Brasthesis incorporates the harnessing straps that hold the prosthesis to the body into a heavy-duty sports bra.
- Trial name
- Brasthesis (NCT05179395)
- Testing
- Brasthesis
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development
PTSD, Depression
National Guard Outreach and Linkage to Treatment
This project will add an evaluation/research component to an existing peer outreach program, now implemented for over 1100 soldiers in the Michigan Army National Guard. Preliminary work will be completed in three areas.
- Conditions
- PTSD, Depression, Reintegration, Veterans Health
- Trial name
- NCT01020981
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Stress Disorders, Post-Traumatic
Wildlife and Wellbeing: An Animal-Assisted Intervention for Veterans With PTSD
This study investigates a novel approach to animal-assisted interventions through a series of wildlife immersion activities (wildlife observation, wildlife rehabilitation and bird feeding/watching) for veterans who have suffered…
- Trial name
- NCT04116489
- Testing
- Forest walk, Wildlife rehabilitation, Wildlife sanctuary observation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Massachusetts, Worcester
Post Traumatic Stress Disorder
Quantifying the Efficacy and Role of Service Dogs for Military Veterans With PTSD
The purpose of this study is to quantify the therapeutic efficacy and role of trained service dogs on socio-emotional functioning among military veterans with posttraumatic stress disorder (PTSD).
- Trial name
- NCT03245814
- Testing
- Service Dog
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Pain, Function
Preventing Persistent Post-Surgical Pain and Dysfunction
Primary Aim: To examine the superior efficacy of ACT versus Attention Control (AC) on postoperative pain intensity and functioning in at-risk Veterans undergoing TKA.
- Conditions
- Pain, Function, Anxiety, Depression
- Trial name
- PrePARE (NCT03965897)
- Testing
- Acceptance and Commitment Therapy (ACT), Attention Control (AC)
- Where
- United States
- Volunteers
- 402 people
- Sponsor
- University of Iowa
Anti-biotic Resistance
Impact of Probiotics for Reducing Infections in Veterans: The IMPROVE Study
The investigators have two hypotheses: (1) The probiotic L. rhamnosus HN001, when compared to placebo, will reduce S. aureus nasal colonization when taken for four weeks. (2) The probiotic L.
- Trial name
- NCT01321606
- Testing
- Lactobacillus rhamnosus HN001
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- VA Office of Research and Development
Chronic Musculoskeletal Pain
Impact of Exercise Training on Pain and Brain Function in Gulf War Veterans
This study is intended to test the influence of weight training on physical symptoms, physical activity and brain structure and function in Gulf War Veterans with chronic widespread muscle pain.
- Trial name
- NCT01350492
- Testing
- Resistance Exercise Training
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- VA Office of Research and Development
Phantom Limb
Cognitive Behavior Therapy (CBT) and Mirror Training for Phantom Limb Pain
The goal of this study is to test whether a combination of cognitive-behavior therapy and mirror training reduces phantom limb pain for veterans with amputations.
- Trial name
- NCT00731614
- Testing
- Cognitive Behavioral Therapy and Mirror Retraining, Supportive therapy, Mirror retraining
- Where
- 3 sites in United States
- Volunteers
- 59 people
- Sponsor
- VA Office of Research and Development
Fibromyalgia
Randomized Controlled Trial of CES for Fibromyalgia
Given recent increasing opioid-related deaths and evidence showing against the use of opioids for non-malignant chronic pain, there is growing need for non-narcotic pain management.
- Trial name
- NCT04115033
- Testing
- Alpha-stim
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Suicide Prevention
Suicide Prevention Study of VA-BIC in the Veteran Population
The VA is committed to reducing suicide in the U.S. Veteran population. Over 6,000 Veterans die from suicide each year, and this risk is particularly high following a psychiatric hospitalization.
- Trial name
- VA-BIC RCT (NCT04446468)
- Testing
- PEACE, Standard Psychiatric Hospital Discharge Care
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- VA Office of Research and Development
Diabetes Mellitus, Depression
Behavioral Activation Therapy for Rural Veterans With Diabetes and Depression
This clinical trial will compare the effectiveness of the Healthy Outcomes through Patient Empowerment (HOPE) intervention to enhanced usual care (EUC) for diabetes and depression at 6 and 12 month follow-up.
- Trial name
- NCT01572389
- Testing
- Healthy Outcomes through Patient Empowerment (HOPE), Enhanced Usual Care
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- VA Office of Research and Development
Myocardial Ischemia, Rheumatic Diseases
Secondary Event Prevention Using Population Risk Management After PCI and for Anti-Rheumatic Medications
Ischemic heart disease (IHD) and its treatment carry profound public health and economic implications. Among Veterans, IHD represents one of the most common causes of death and disability, with over 500,000 affected individuals'…
- Trial name
- SEPPRMACI-ARM (NCT02694185)
- Testing
- Caplan IVR
- Where
- 5 sites in United States, Puerto Rico
- Volunteers
- 5,269 people
- Sponsor
- VA Office of Research and Development
Multiple Chronic Conditions, Decision Making, Shared
Effect of Patient Priorities Care Implementation in Older Veterans With Multiple Chronic Conditions
The investigators will conduct a randomized control trial enrolling 420 older Veterans with multiple chronic conditions receiving primary care at the Michael E.
- Trial name
- PPC (NCT04922320)
- Testing
- Patient Priorities Care, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 437 people
- Sponsor
- VA Office of Research and Development