Clinical trials: Veteran
Substance Use, Substance Use Disorders
Developing a Telehealth Model to Improve Treatment Access for Rural Veterans With Substance Use Disorders
This project will pilot-test and obtain stakeholder input on a telehealth-delivered substance use disorder (SUD) care model (with initial engagement and ongoing MI-CBT treatment) with the goal of increasing treatment utilization…
- Conditions
- Substance Use, Substance Use Disorders, Substance Dependence, Veterans
- Trial name
- VetReach (NCT05348317)
- Testing
- VetReach
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- VA Office of Research and Development
Anxiety and Fear, PTSD
K08 VR Fear Conditioning
The goal of this clinical trial is to learn how people respond to fear-related experiences in a virtual reality (VR) environment.
- Conditions
- Anxiety and Fear, PTSD, Veteran
- Trial name
- NCT07216222
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Post-traumatic Stress Disorder (PTSD), Cardiovascular Diseases
NightWare and Cardiovascular Health in Veterans With PTSD
The purpose of this study is to learn more about the effectiveness of a prescription wrist-wearable device called NightWare (NW) on improving sleep in Veterans with nightmares related to posttraumatic stress disorder (PTSD).
- Conditions
- Post-traumatic Stress Disorder (PTSD), Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness
- Trial name
- NCT06419959
- Testing
- NightWare
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Suicide, Attempted, Suicide, Completed
Virtual Reality Lethal Means Safety Training
The goal of this randomized clinical trial is to determine whether a virtual reality (VR) training program can help healthcare providers improve their skills in discussing suicide prevention and safe storage of firearms and…
- Conditions
- Suicide, Attempted, Suicide, Completed, Suicide Prevention, Mental Health Training
- Trial name
- NCT07219355
- Testing
- Virtual Reality Lethal Means Safety Training, 2D Video Training
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Chronic Pain, Veterans
Co-Adaptation of an Digital Pain Management Program for Canadian Veterans
The goal of this study is to gather feedback from Canadian Veterans living with chronic pain, and clinicians serving Canadian Veterans, on an existing digital psychology program for self-management of chronic pain delivered…
- Trial name
- ADOPTCanVets (NCT07818980)
- Testing
- Self-Guided Digital Acceptance and Commitment Therapy Program
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University Health Network, Toronto
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Aging, Veterans
Geri Pride: Feasibility Pilot of a Group Intervention for Older Veterans
There are over one million Veterans who identify as lesbian, gay, bisexual, (LGB) or a related identity. Older LGB Veterans face unique hurdles as they age, including stress, anxiety, heart disease, cancer, decreased ability to…
- Conditions
- Aging, Veterans, Social Determinants of Health, Health Disparate Minority and Vulnerable Populations
- Trial name
- NCT07831759
- Testing
- Geri Pride Health Promotion Group
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Post-traumatic Brain Injury Depression, Veteran Health
Development of Low-Intensity Focused Ultrasound for Post Traumatic Brain Injury Depression
The goal of this clinical trial is to learn about evaluate the safety, tolerability, and feasibility of MRI-guided LIFU targeting the sgACC in Veterans with post-traumatic brain injury depression.
- Trial name
- NCT07828483
- Testing
- Active Low-Intensity Focused Ultrasound (LIFU)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stanford University
Spinal Cord Injuries (SCI), Spinal Cord Injury
mSCI: Mobile Health App for Veterans With SCI and Caregivers
Caregivers of persons with Spinal Cord Injury (SCI) face increased risk of psychological distress, health problems, reduced quality of life, relationship strain, and restrictions in social and work participation.
- Conditions
- Spinal Cord Injuries (SCI), Spinal Cord Injury, Spinal Cord Injuries (Complete and Incomplete), Family Caregivers
- Trial name
- NCT07269977
- Testing
- iMHERE 2.0. A mobile health App designed to support veterans with SCI manage their self care, and their caregivers
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cigarette Smoking, Veterans
Evaluating an Innovative Tobacco Treatment Approach for Veterans in Substance Use Treatment
Veterans with substance use disorders smoke at extraordinarily high rates and have high rates of smoking-related death and disease.
- Trial name
- Co-STOP (NCT07809854)
- Testing
- Healthy Changes Nicotine Replacement Therapy (NRT), Cessation Treatment Nicotine Replacement Therapy (NRT), Cessation Treatment Counseling
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- VA Office of Research and Development
Binge-Eating Disorder, Bulimia Nervosa
Building an Equitable and Accessible System of Eating Disorder Care for VA, DoD, and Underrepresented Americans
When untreated, eating disorders present with tremendous burdens to affected active duty Service members and Veterans and their families, and are very costly to the DoD and VA healthcare system.
- Conditions
- Binge-Eating Disorder, Bulimia Nervosa, Veterans Health, Cognitive Behavioral Therapy
- Trial name
- EASED (NCT05304104)
- Testing
- Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- VA Connecticut Healthcare System
Insomnia, PTSD
Treatments in Women Veterans With Insomnia and PTSD
This pilot trial will compare trauma-informed Cognitive Behavioral Therapy for Insomnia (CBT-I) to a psychoeducational intervention in women Veterans with comorbid insomnia and posttraumatic stress disorder (PTSD).
- Conditions
- Insomnia, PTSD, Women Veterans
- Trial name
- NCT05683132
- Testing
- Trauma-Informed CBT-I, PTSD Psychoeducation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Tobacco Dependence, Veterans
Identifying Effective Treatment for Veterans Unwilling to Quit Smoking
This project will generate knowledge about the effectiveness of Enhanced Chronic Care, an intervention designed to enhance treatment use and smoking abstinence in Veterans who are initially unwilling to quit.
- Trial name
- NCT04061720
- Testing
- Enhanced Chronic Care, Standard Care
- Where
- United States
- Volunteers
- 502 people
- Sponsor
- VA Office of Research and Development
Veterans, Tobacco Use Disorder
Varenicline for Smoking Reduction in Veterans Not Ready To Quit
In order to reduce the prevalence of cigarette smoking among Veterans, it is vital that healthcare providers offer effective tobacco treatment to all Veterans who smoke, including those not ready to make a quit attempt.
- Conditions
- Veterans, Tobacco Use Disorder, Cigarette Smoking, Tobacco Dependence
- Trial name
- NCT06966362
- Testing
- Motivation-Phase Varenicline, Motivation-Phase Nicotine Mini-Lozenge, Cessation-Phase Combination Nicotine Replacement Therapy (NRT)
- Where
- 4 sites in United States
- Volunteers
- 400 people
- Sponsor
- VA Office of Research and Development
Veteran
OpRESTORE AI-Patient Navigator Study
OpRESTORE is a national NHS service that supports UK veterans with complex physical health problems linked to their military service.
- Trial name
- NCT07474584
- Testing
- AI-OpRESTORE healthcare navigator, OpRESTORE healthcare navigation
- Where
- United Kingdom
- Volunteers
- 1,389 people
- Sponsor
- Imperial College Healthcare NHS Trust
Low Back Pain, Patient Acceptance of Health Care
Veterans Response to Dosage in Chiropractic Therapy
This study evaluates how Veterans with chronic low back pain (cLBP) respond to varying doses of chiropractic therapy and how health services utilization are impacted as a result. There are 2 phases in this study.
- Conditions
- Low Back Pain, Patient Acceptance of Health Care, Veterans Health
- Trial name
- VERDICT (NCT04087291)
- Testing
- Chiropractic Care
- Where
- 4 sites in United States
- Volunteers
- 766 people
- Sponsor
- Palmer College of Chiropractic
Spinal Cord Injury, Depression - Major Depressive Disorder
Psilocybin to Treat Depression in Spinal Cord Injury
The main goal of this study is to determine if psilocybin is safe for use in people with SCI. The study will measure how people with SCI respond to three psilocybin doses: low (5mg), medium (10mg), and high (25mg).
- Conditions
- Spinal Cord Injury, Depression - Major Depressive Disorder, Veteran
- Trial name
- STOP (NCT07251491)
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Post Traumatic Stress Disorder, Cannabis Use
Warrior CARE: Cannabis Behavioral Health
This study is a randomized, controlled clinical trial to examine the therapeutic potential of cannabinoids for treating veterans with PTSD and suicidal ideation.
- Conditions
- Post Traumatic Stress Disorder, Cannabis Use, Suicide, Veterans
- Trial name
- CBH (NCT06381180)
- Testing
- Tetrahydrocannabinol, Cannabidiol
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Wayne State University
Stigma, Co-Occurring Disorders
Honest, Open, Proud (HOP): A Peer Delivered, Co-occurring Disorders Intervention for Justice-involved Veterans
As many as two-thirds of Justice-involved Veterans (JIVs) have a substance-use disorder (SUD), and up to 51% have a mental health (MH) condition; however, fewer than one-third of JIVs receive MH or SUD treatment, and addressing…
- Conditions
- Stigma, Co-Occurring Disorders, Substance Use Disorder, Mental Health Disorder
- Trial name
- HOP (NCT07742722)
- Testing
- Veterans Affairs-Honest, Open, Proud
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Veteran Aged 65 and Older
Promoting Cognitive Resilience and Reducing Frailty in Older Veterans With Bright Light Therapy
Frailty is a multifactorial syndrome characterized by vulnerability to stressors that is intricately linked to cognitive impairment and mortality risk.
- Trial name
- Brite-VET (NCT05631236)
- Testing
- Bright Light Therapy (AYO Glasses)
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development