Clinical trials: Uterus; Scar
Cesarean Section Complications, Uterine Scar Diverticulum
Preventing Isthmocele After Cesarean Section
Cesarean section accounts for nearly 30% of births in Canada, and is the most commonly performed surgery by Obstetrician Gynecologists.
- Conditions
- Cesarean Section Complications, Uterine Scar Diverticulum, Uterine Scar From Previous Cesarean Delivery
- Trial name
- (PICS) (NCT03826459)
- Testing
- Non-Locking Uterine Closure, Locked Uterine Closure
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Cesarean Section; Dehiscence
Mri in Evaluation of Cesarean Section Scar Niche
To evaluate cesarean section scar and the lower uterine segment in non pregnant woman by MRI to : 1. Assess the clinical symptoms like postmenstrual spotting or prolonged menstrual bleeding, dysmenorrhea, chronic pelvic pain and…
- Trial name
- NCT03911622
- Testing
- MRI
- Volunteers
- 30 people
- Sponsor
- Assiut University
Placenta Accreta, Third Trimester, Uterine Scar Dehiscence
Ultrasound Model to Help Differentiate Between Placenta Accreta Spectrum and Uterine Dehiscence in 3rd Trimester Pregnancies
By using 2d Ultrasound on 3rd trimester pregnant women, a model is made to help differentiate between placenta accreta spectrum and uterine scar dehiscence before operative action to help prepare multi-disciplinary steps if needed
- Trial name
- NCT07236060
- Testing
- 2D ultrasound doppler
- Volunteers
- 50 people
- Sponsor
- Assiut University
Adhesions Pelvic, Adhesion; Uterus
Prediction of Vesicouterine Adhesions by Transvaginal Sonographic Sliding Sign Technique: a Validation Study
The aim of this study is to evaluate the predictive value of the real-time dynamic TVS sliding sign for vesicouterine pouch adhesions in women and to test the inter- and intraobserver agreement of this new technique.
- Conditions
- Adhesions Pelvic, Adhesion; Uterus, Adhesion; Bladder
- Trial name
- NCT05862155
- Where
- Netherlands
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Cesarean Scar Defects, Cesarean Section Complications
Diagnostic Accuracy of Saline Sonohystrography vs. 3D Transvaginal Ultrasound for Cesarean Scar Defect Assessment
To compare accuracy of three dimensional transvaginal ultrasound versus the "gold standard" saline infused sonography for assessing the characteristics, frequency and appearance of caesarean scar defects in symptomatic patients…
- Conditions
- Cesarean Scar Defects, Cesarean Section Complications, Uterine Scar Dehiscence, Vaginal Birth After Cesarean
- Trial name
- NCT05996926
- Testing
- Three-Dimensional Transvaginal Ultrasound (3D TVS), Saline-Infused Sonography (Sonohystrography)
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Herpes Genitalis, Genital Wart
Safety and Efficacy of Laser Therapy in Gynaecology
The aim of this study is to retrospectively evaluate the effectiveness and safety of Er:YAG laser for treatment of different gynecological indication, e.g.
- Conditions
- Herpes Genitalis, Genital Wart, Lichen Sclerosus, Cervical Intraepithelial Neoplasia
- Trial name
- NCT04073082
- Where
- Slovenia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Juna d.o.o.
Uterine Scar, Cesarean Section Complications
Single or Double-layer Uterine Closure Techniques
There are different surgical techniques of uterine closure during cesarean. A growing data has suggested that the closure technique has an effect on uterine scar healing.
- Conditions
- Uterine Scar, Cesarean Section Complications, Cesarean Section; Dehiscence
- Trial name
- NCT03629028
- Testing
- Residual myometrium thickness, Niche Presence, Adjacent myometrium thickness
- Where
- Turkey (Türkiye)
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Safak Baran Yilmaz
Uterine Scar
Difference Between Monofilament Versus Multifilament Suture Material in Isthmocele Formation
This thesis conducts the effect of using different suture materials on the development of uterine scar niche after cesarean section.
- Trial name
- NCT06741371
- Testing
- Monocryl
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Thinned-out Lower Uterine Segment Scar Previous Cesarean Section
Comparison of Purse String Suture vs Transverse Mattress Suture to Maintain Hemostasis in Thinned-out Caesarean Sections Scars
Brief Summary The goal of this clinical trial is to compare the effectiveness of purse-string suture versus transverse mattress suture for achieving hemostasis in women with thinned-out lower uterine segment scars undergoing…
- Trial name
- NCT07758959
- Testing
- Purse-String Suture, Transverse Mattress Suture
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Natasha Bushra
Uterine Scar
Safety of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars
The purpose of this study is to evaluate the safety of umbilical cord mesenchymal stem cell local intramuscular injection for treatment of uterine scars by a prospective, single-center, open, and single-arm clinical trial.
- Trial name
- NCT03181087
- Testing
- Umbilical cord MSCs
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Uterine Scar Defect
Suture of UTerus and Ultrasound Repair Evaluation
This study compares three techniques of uterine closure on myometrium thickness evaluated by ultrasound six months after the primary cesarean.
- Trial name
- SUTURE (NCT01860859)
- Testing
- Closure of the hysterotomy at the time of primary cesarean
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Scar; Previous Cesarean Section
Preoperative and Intraoperative Sonographic Assessment of Lower Uterine Segment Thickness at Term in Women With Previous Cesarean Delivery - a Ultrasound Method Comparison Study
This prospective, clinical, observational study compares preoperative and intraoperative sonographic assessment of lower uterine segment of women who underwent ≥ second cesarean section.
- Trial name
- SALUTARY (NCT02827604)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Cesarean Section Complications, Uterine Bleeding
Platelet Rich Plasma for Uterine Scar
When vessel wall injury occurs, platelets become activated, releasing more than 30 bioactive proteins, many of which have a fundamental role in hemostasis, inflammation and ultimate wound healing.
- Conditions
- Cesarean Section Complications, Uterine Bleeding, Pelvic Pain, Menstrual Irregularity
- Trial name
- AA-PRP (NCT05224726)
- Testing
- Platelet Rich Plasma
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Cesarean Scar Defect (Isthmococele)
Incision-Parallel Double-Layer Non-Locking Versus Single-Layer Locked Uterine Closure After Primary Caesarean Delivery: A Randomized Controlled Trial
This randomized controlled trial was conducted to compare two uterine closure techniques in women undergoing primary cesarean delivery.
- Trial name
- NCT07841028
- Testing
- Single-Layer Locked Uterine Closure, Double-Layer Incision-Parallel Nonlocking Uterine Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Onur Karaaslan
Adhesion; Uterus, Internal
Use of an Intra Uterine Balloon to Prevent Recurrent Adhesions (REpAIR)
Patients suffering of subfertility as a consequence of intrauterine adhesions could be treated with hysteroscopic adhesiolysis. Adhesion recurrence may occur postoperative.
- Trial name
- NCT03446755
- Testing
- intra uterine Cook balloon
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- University Hospital, Ghent
Placenta Accreta
Comparison Between the Role of Transabdominal Ultrasound Versus Transvaginal Ultrasound in Evaluation of Placental Invasion in Cases of Placenta Previa Anterior Wall With Previous Uterine Scar
Objective: To compare between the role of Transabdominal ultrasound versus Transvaginal ultrasound in evaluation of placental invasion in cases of placenta previa anterior wall with previous uterine scar applying the unified…
- Trial name
- NCT03437291
- Testing
- Cesarean section, Transabdominal ultrasound, Transvaginal ultrasound
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Pregnancy Related, Labor Complication
Mechanical Dilation of the Cervix in a Scarred Uterus
To determine if mechanical labour induction can offer a safer and effective alternative to prostaglandins to women with previous caesarean section attempting trial of labour after caesarean (TOLAC).
- Conditions
- Pregnancy Related, Labor Complication, Cesarean Section; Dehiscence
- Trial name
- MEDICS (NCT03471858)
- Testing
- Cervical balloon, Prostaglandins
- Where
- Singapore
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Singapore
Cesarean Scar Diverticulum
A Randomized Controlled Study of Uterine Incision Diverticulum Repair vs. no Repair During Second/Third Cesarean Section
The goal of this study is to assess the efficacy and safety of uterine incision diverticulum repair during repeat cesarean section.The main questions it aims to answer are: Can this surgical method improve the symptom of…
- Trial name
- NCT06612957
- Testing
- Repair of uterine cicatricial diverticulum
- Volunteers
- 60 people
- Sponsor
- Shanghai First Maternal and Infant Health Hospital affiliated to Tongji University Medical School
Cesarean Wound Disruption
The Influence of Endometrial Suturing on the Risk of Uterine Scar Defect
Caesarean section (CS) is the commonest major operation performed on women worldwide with progressively rising incidence. Consequently, long-term adverse sequelae due to uterine scar defect have been increasing.
- Trial name
- NCT03851003
- Testing
- Endometrial suturing, Non- endometrial suturing, Vaginal ultrasonography
- Where
- Israel
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Isthmocele, Cesarean Scar Defect
Clinical Impact of Uterine Repair During Cesarean Section With Barbed Suture on the Incidence of Isthmocele
Pregnant women, irrespective of their pregnancy risk, who undergo a cesarean section for any reason will be randomized to one of two suturing techniques: conventional suture or barbed suture for uterine repair after the cesarean…
- Conditions
- Isthmocele, Cesarean Scar Defect, Pelvic Pain, Spotting
- Trial name
- CESARIS (NCT06691750)
- Testing
- Barbed suture, Conventional smooth suture
- Where
- Spain
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona