Clinical trials: Tooth Extraction
Dehiscence, Tooth Extraction
Effect of Collagen Membrane on Ridge Preservation
This study will evaluate whether adding a resorbable collagen membrane to an anorganic bone-collagen composite (ABCC) graft improves ridge preservation after tooth extraction.
- Conditions
- Dehiscence, Tooth Extraction, Alveolar Bone Loss
- Trial name
- NCT07580495
- Testing
- Minimally Invasive tooth extraction, Alveolar ridge preservation with ABCC, Resorbable collagen membrane (InterCollagen® Guide)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Debora Dias
Tooth Extraction
The Indications of First Molar Extraction at Tufts University, School of Dental Medicine
The aim of the present study is to investigate whether there has been a change of criteria for tooth extraction at Tufts University School of Dental Medicine (TUSDM) from 2005 to 2018.
- Trial name
- NCT04705181
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Tufts University
Malocclusion, Corticotomy
Evaluation of Corticotomy-Assisted Canine Retraction Rate
The goal of this split-mouth randomized clinical trial is to evaluate the effectiveness of corticotomy on maxillary canine retraction rate compared to conventional orthodontic techniques.
- Conditions
- Malocclusion, Corticotomy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- BMU/2026/8506 (NCT07879066)
- Testing
- Experimental: Corticotomy¬-Assisted Canine Retraction, Active Comparator / Control: Conventional Canine Retraction
- Where
- Bangladesh
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Autoimmune Rheumatic Diseases, Tooth Extraction
Antibiotic Prophylaxis After Simple Tooth Extraction in Immunosuppressed Patients With Autoimmune Rheumatic Diseases
This randomized, double-blind, placebo-controlled clinical trial aims to evaluate whether single-dose amoxicillin prophylaxis administered prior to simple tooth extraction reduces postoperative infection rates inpatients with…
- Conditions
- Autoimmune Rheumatic Diseases, Tooth Extraction, Infection Prevention, Antibiotic Prophylaxis
- Trial name
- PRO-EXOD (NCT07275580)
- Testing
- Amoxicillin
- Where
- Brazil
- Volunteers
- 352 people
- Sponsor
- University of Sao Paulo General Hospital
Alveolar Ridge Preservation, Bone Regeneration
Using Different Biomaterials to Preserve Bone After Tooth Extraction
This four-arm randomized controlled clinical trial evaluated the clinical, radiographic, and histological outcomes of different approaches to alveolar ridge preservation following tooth extraction.
- Conditions
- Alveolar Ridge Preservation, Bone Regeneration, Tooth Extraction, Dental Implants
- Trial name
- NCT07394738
- Testing
- Allograft, Autogenous Dentin Graft, Hyaluronic Acid Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Inonu University
Wound Healing, Alveolitis of Jaw
Effect of Curcumin Topical Spray on Wound Healing After Tooth Extraction
This randomized, single-blind, controlled clinical trial aims to evaluate the effects of a topical curcumin spray on post-extraction wound healing and postoperative symptoms in adults undergoing first molar extraction.
- Conditions
- Wound Healing, Alveolitis of Jaw, Tooth Extraction, Curcumin
- Trial name
- NCT07874789
- Testing
- Curcumin Topical Spray, Chlorhexidine Topical Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Tooth Extraction Site Healing, Alveolar Ridge Preservation
Biomaterials Exposed to Oral Environment: Which One is the Appropriate Option?
After tooth extraction, bone loss can compromise future dental implant treatment. Dentists often use biomaterials to preserve bone, but in many cases these materials are left exposed to the oral environment, where saliva and…
- Trial name
- NCT07589751
- Testing
- Alveolar Ridge Reconstruction
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Postoperative Pain, Mandibular Molar Extraction
Effect of Intraoperative Tetracycline on Postoperative Pain After Mandibular Molar Extraction
Postoperative pain is a common complication following mandibular molar extraction and can negatively affect patient comfort and recovery.
- Conditions
- Postoperative Pain, Mandibular Molar Extraction, Tooth Extraction
- Trial name
- TETRAMOL (NCT07738861)
- Testing
- Tetracycline, No Intrasocket Medicament
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Analgesics, Opioid, Acute Pain
Alternatives to Dental Opioid Prescribing After Tooth Extraction
The goal of this clinical trial is to test a three-item intervention in oral surgeons who remove teeth. The main questions it aims to answer are: Can the intervention reduce opioid prescriptions to adolescents and young adults…
- Conditions
- Analgesics, Opioid, Acute Pain, Tooth Extraction, Adolescent
- Trial name
- ADOPT (NCT06275191)
- Testing
- Multicomponent intervention, Usual care
- Where
- United States
- Volunteers
- 38,159 people
- Sponsor
- Douglas Oyler
Alveolar Ridge Preservation, Tooth Loss
Volumetric Efficacy of Alveolar Ridge Preservation
The goal of this clinical trial is to compare the effectiveness of four post-extraction socket management approaches in preserving alveolar ridge dimensions following tooth extraction in adults requiring implant-supported…
- Conditions
- Alveolar Ridge Preservation, Tooth Loss, Tooth Extraction, Tooth Extraction Site Healing
- Trial name
- ARP (NCT07812883)
- Testing
- Spontaneous Healing, d-PTFE Membrane, Leukocyte- and Platelet-Rich Fibrin (L-PRF)
- Where
- Chile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Tooth Loss and Rehabillitation, Immediate Implant Placement in Mandibular Molar Extraction Sockets
Comparison Between Xenograft and Extended PRF as Jumping Gap Grafting Material Versus Natural Healing of the Socket Without Any Material.
This study aims to clinically and digitally evaluate immediate implants placed in mandibular molar extraction sockets and compare the outcomes of xenograft, e-PRF, and no grafting material within the jumping gap.
- Conditions
- Tooth Loss and Rehabillitation, Immediate Implant Placement in Mandibular Molar Extraction Sockets, Jumping Gap
- Trial name
- NCT07797452
- Testing
- Xenograft jumping gap filling material, e-PRF jumping gap filling material
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Implant Site Reaction, Tooth Extraction Status Nos
Elamrousy Modified Approach for Socket Shield Technique
The current trial aim was to evaluate clinically and radiographically the changes around dental implants inserted immediately in maxillary anterior esthetic zone using a novel combination of autogenous demineralized dentin graft…
- Conditions
- Implant Site Reaction, Tooth Extraction Status Nos, Dental Implant Failed
- Trial name
- NCT06043037
- Testing
- Elamrousy Novel Approach for Immediate Implant Placement Using Socket Shield Technique, Immediate Implant Placement Using Socket Shield Technique alone
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Tooth Extraction Status Nos
The Effect of Chamomile on Healing After Tooth Extraction
After impacted wisdom tooth extraction, patients frequently complain of pain, edema, and limited mouth opening. After the procedure, patients are routinely recommended to use chlorhexidine and physiological serum-based…
- Trial name
- NCT06770166
- Testing
- Physiological serum mouthwash, Chlorhexidine mouthwash, Chamomile mouthwash
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- reyhan saglam-dogu
Tooth Extraction, Alveolar Bone Loss
Autogenous Dentin Graft for Alveolar Ridge Preservatio
When a tooth is extracted, the bone around the empty socket naturally shrinks over time, which can make it difficult to place a dental implant later without additional bone-building procedures.
- Trial name
- ARF-PRF (NCT07789262)
- Testing
- Autogenous Dentin Graft, Platelet-Rich Fibrin (PRF), Freeze-Dried Bone Allograft (FDBA)
- Where
- Turkey (Türkiye)
- Volunteers
- 9 people
- Sponsor
- Ankara Yildirim Beyazıt University
Dental Crowding, Dental Occlusion, Traumatic
Exploration of the Utility of Dental-dedicated MRI for Dentistry
This description observational research is comparative in design, that is comparing existing standard clinical dental images, not obtained in this study, to test (i.e., ddMRI) images.
- Conditions
- Dental Crowding, Dental Occlusion, Traumatic, Endodontic Disease, Orthodontic Treatment
- Trial name
- NCT06948162
- Testing
- dental-dedicated MRI (ddMRI)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction
THBC/CGF for Alveolar Bone Regeneration: A Real-World Study
This study aims to combine real-world research with relevant bone repair materials and techniques to improve alveolar bone resorption in extraction sockets following impacted wisdom tooth removal, while achieving effective bone…
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction, Tooth, Impacted
- Trial name
- NCT07779421
- Testing
- Temperature-sensitive hydroxybutyl chitosan-loaded concentrated growth factor, Temperature-sensitive hydroxybutyl chitosan, Autologous Concentrated Growth Factor
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Stomatological Hospital Affiliated with Fujian Medical University
Facial Swelling, Tooth Position Anomalies
Platelet-Rich Fibrin as an Antibiotic Delivery Vehicle in Mandibular Third Molar Surgery
The present study aims to evaluate the effect of platelet-rich fibrin (PRF) used as a local antibiotic delivery vehicle on postoperative outcomes, including facial swelling, trismus, and pain, following mandibular third molar…
- Conditions
- Facial Swelling, Tooth Position Anomalies, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT07764757
- Testing
- Antibiotic-enriched Platelet-Rich Fibrin (PRF), Platelet-Rich Fibrin (PRF)
- Where
- Italy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Radiographic Evaluation, Bone Density
Effect of Thymoquinone 0.2% Gel on Bone Density, Bone Width, and Socket Preservation After Tooth Extraction
This study aims to evaluate the clinical and radiographic effects of 0.2% Thymoquinone gel on bone density, bone width, and socket preservation after tooth extraction.
- Conditions
- Radiographic Evaluation, Bone Density, Bone Width, Socket Preservation
- Trial name
- NCT07765745
- Testing
- Gel foam, Thymoquinone gel + gel foam, Nano-formulated 0.2% thymoquinone gel + gel foam
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University
Alveolar Ridge Preservation Post-Extraction Bone Healing Dental Implant Site Development Tooth Loss
Early Dental Implant Installation in Regeneration Sites: a Prof of Concept Prospective Case Study
This study will evaluate bone healing after tooth extraction and alveolar ridge preservation, a common procedure used to maintain the bone volume needed for future dental implant placement.
- Trial name
- NCT07766057
- Testing
- Alveolar Ridge preservation and early implant placement
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Franco Cavalla
Tooth Extraction, Immediate Dental Implant Placement
IMMEDIATE IMPLANTS: GRAFT VS NO GRAFT
This prospective, randomized, controlled, split-mouth clinical trial aims to evaluate the effect of bone grafting on mandibular bone microstructure following immediate implant placement using fractal analysis of panoramic…
- Conditions
- Tooth Extraction, Immediate Dental Implant Placement, Alveolar Bone Healing After Dental Extraction
- Trial name
- NCT07761195
- Testing
- BONE GRAFTING, NO BONE GRAFT
- Volunteers
- 40 people
- Sponsor
- sema kaya