Clinical trials: Tobacco-Related Carcinoma
Tobacco-Related Carcinoma
Manipulating E-Cigarette Nicotine to Promote Public Health
This clinical trial explores the manipulation of e-cigarette (EC) nicotine to promote public health. Researchers are trying to understand and gather information about how the strength, form, and structure of nicotine in products…
- Trial name
- NCT06448351
- Testing
- Biospecimen Collection, Carbon Monoxide Measurement, Vaping session
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Tobacco-Related Carcinoma
THRIVE Study: Understanding How Oral Nicotine Pouches Affect Public Health
Although nicotine pouches have been gaining popularity over the last few years, little known about how nicotine pouch users actually use these products. This study will be comprised of adults who use nicotine pouches.
- Trial name
- THRIVE (NCT07503925)
- Testing
- Biospecimen Collection, Nicotine Oral Pouch, Survey Administration
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Smoking, Tobacco, Tobacco-Related Carcinoma
The Lung Screening, Tobacco and Health Project
The purpose of this study is to compare intensive telephone counseling (ITC) plus the nicotine patch vs. standard telephone counseling plus the nicotine patch (Usual Care; UC) among current smokers undergoing lung cancer…
- Conditions
- Smoking, Tobacco, Tobacco-Related Carcinoma, Tobacco Use, Lung Cancer Screening
- Trial name
- NCT03200236
- Testing
- Intensive Telephone Counseling (8 sessions) with nicotine replacement, Usual Care: Telephone counseling (3 sessions) with nicotine replacement
- Where
- 7 sites in United States
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Cigarette Smoking-Related Carcinoma
Electronic Cigarette Use During Pregnancy
Aim 1: To compare the overall toxicant exposure in pregnant women who use electronic cigarettes (e-cigs, vapor, e-liquid, e-juice, vape, vaping devices) compared to women who smoke conventional cigarettes. Aim 2.
- Trial name
- NCT03480373
- Where
- 6 sites in United States
- Volunteers
- 182 people
- Sponsor
- UConn Health
Tobacco-Related Carcinoma, Smoking &Amp; Tobacco Cessation
Electronic Quitline Referral With Enhanced Academic Detailing for the Promotion of Smoking Cessation
This phase IV clinical trial determines the impact of implementing a Quitline electronic (e)Referral system with an enhanced academic detailing implementation strategy on Quitline reach, tobacco cessation assistance and…
- Trial name
- CONNECT (NCT04969978)
- Testing
- Enhanced Academic Detailing, Informational Intervention
- Where
- United States
- Volunteers
- 9,133 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Lung Cancer, Tobacco Use Disorder
Feasibility of Delivering a Quitline Based Smoking Cessation Intervention in Cancer Patients
RATIONALE: Continued smoking after a cancer diagnosis has important health consequences beyond the risks associated with smoking in the general population.
- Conditions
- Lung Cancer, Tobacco Use Disorder, Breast Cancer, Colorectal Cancer
- Trial name
- NCT01434342
- Testing
- Nicotine Replacement Patch
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Wake Forest University Health Sciences
Tobacco-Related Carcinoma
Nicotine and Tobacco Message Framing Among LGBT Young Adults
This trial refines and evaluates how cultural targeting influences the effectiveness of anti-tobacco messages among lesbian, gay, bisexual, and transgender (LGBT) young adults at risk for the use of more than one tobacco product…
- Trial name
- NCT05972941
- Testing
- Health communications
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Tobacco-Related Carcinoma
Episodic Future Thinking and Future Thinking Priming for Smoking Cessation
This trial studies the main and interactive effects of episodic future thinking and future thinking priming tasks on helping participants to quit smoking.
- Trial name
- NCT04297332
- Testing
- Behavioral Intervention, Informational Intervention, Nicotine Replacement
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Lung Carcinoma, Tobacco-Related Carcinoma
Support and Outreach to Increase Screening for Lung Cancer in Patients With a History of Smoking
This clinical trial tests how well providing education improves screening for lung cancer in patients with a history of smoking. Screenings may help doctors find lung cancer sooner when it may be easier to treat.
- Trial name
- NCT05679349
- Testing
- Survey Administration, Educational Activity, Electronic Health Record Review
- Where
- United States
- Volunteers
- 822 people, healthy volunteers welcome
- Sponsor
- Ronald Myers
Bronchial Epithelial Dysplasia, Chronic Obstructive Pulmonary Disease
Oral Iloprost for the Prevention of Lung Cancer In Former Smokers
This phase II trial tests whether oral iloprost works in preventing lung cancer (chemoprevention) in former smokers. Oral iloprost has previously been shown to reduce abnormal lung cells in former smokers, suggesting a clinically…
- Conditions
- Bronchial Epithelial Dysplasia, Chronic Obstructive Pulmonary Disease, Lung Carcinoma, Stage I Lung Cancer AJCC v8
- Trial name
- NCT05411107
- Testing
- Biospecimen Collection, Bronchial Brush Biopsy, Bronchoscopy
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Lung Cancer, Tobacco Use Disorder
Standard Medical Care or Urgent Chest X-ray in Diagnosing Lung Cancer in Smokers With Chest Symptoms Who Are Older Than 60 Years
RATIONALE: Diagnostic procedures, such as an urgent chest x-ray, may help in planning cancer treatment. It is not yet known whether standard medical care is more effective than an urgent x-ray in diagnosing lung cancer in smokers…
- Trial name
- NCT01344005
- Testing
- caregiver-related intervention or procedure, questionnaire administration, quality-of-life assessment
- Volunteers
- 386 people
- Sponsor
- Wales Cancer Trials Unit
Cigarette Smoking-Related Carcinoma
Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers
This phase II trial tests whether broccoli seed and sprout extract works to break down cancer causing substances of tobacco in heavy smokers. Smokers are at increased risk for developing lung, head and neck, and other cancers.
- Trial name
- NCT05121051
- Testing
- Biospecimen Collection, Broccoli Sprout/Broccoli Seed Extract Supplement, Questionnaire Administration
- Where
- 3 sites in United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
HNSCC, Head and Neck Cancer
Broccoli Sprout Extract in Preventing Recurrence in Patients With Tobacco-Related Head and Neck Squamous Cell Cancer
This study is being done to see whether Avmacol®, a dietary supplement made from broccoli sprout and seed extract powder, induces changes in inner cheek cells that may be protective against environmental toxins such as tobacco.
- Conditions
- HNSCC, Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Tobacco-Related Carcinoma
- Trial name
- NCT03182959
- Testing
- Avmacol®
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Arizona
Tobacco-Related Carcinoma, Smoking Cessation
Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities
This study evaluates whether the Smokefree Family Living (SFL) intervention improves quit rates (smoking cessation) and exposure to tobacco contamination that stays in items such as, carpets, walls, and furniture, even after the…
- Trial name
- NCT07049757
- Testing
- Smoking cessation education, Survey Administration, Telephone-Based Intervention
- Where
- United States
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tobacco-Related Carcinoma
Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers
This clinical trial evaluates the effect of message framing on smoking behaviors among lesbian, gay, bisexual, transgender, queer (LGBTQ+) young adults who use nicotine and/or tobacco.
- Trial name
- NCT06644664
- Testing
- Health Education, Interview, Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Lung Cancer, Tobacco Use Disorder
Green Tea Extract in Preventing Cancer in Former and Current Heavy Smokers With Abnormal Sputum
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. Green tea extract may keep cancer from forming.
- Trial name
- NCT00573885
- Testing
- defined green tea catechin extract
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- British Columbia Cancer Agency
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma (HNSCC)
Effects of Avmacol® in the Oral Mucosa of Patients Following Curative Treatment for Tobacco-related Head and Neck Cancer
Avmacol is an over-the-counter dietary supplement containing broccoli seed and sprout extracts in tablet form, hypothesized to activate protective cellular pathways including detoxication.
- Conditions
- Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma (HNSCC), Head and Neck Carcinoma, Head and Neck
- Trial name
- NCT03268993
- Testing
- Avmacol
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Pittsburgh
Cigarette Smoking-Related Carcinoma
Text Message and Mail Delivery of Tailored Educational Materials to Improve Access to Resources for Smoking Cessation of Menthol Tobacco Cigarettes
This clinical trial compares the impact of receiving educational materials containing relevant content about risks from smoking menthol cigarettes which include links to the New York (NY) Smoke-Free website by text message or…
- Trial name
- NCT07857681
- Testing
- Educational Intervention, Internet-Based Intervention, Smartphone Application-based Intervention
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Carcinoma, Squamous Cell of Head and Neck, Tobacco Use Disorder
Smoking Tobacco Cessation Integrated Program of Patients Treated for the Head and the Neck Cancer
Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosa of the upper aero-digestive tract. They are the 6th most prevalent type of cancer worldwide.
- Trial name
- INTENT (NCT03788785)
- Testing
- Experimental arm, Control arm
- Where
- 3 sites in France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Tobacco-Related Carcinoma
Oral Nicotine Product Messaging to Communicate Risk of Use for Young Adults
This clinical trial tests the effect of different types of oral nicotine pouch (ONP) messaging to communicate risk of using these products for young adults.
- Trial name
- NCT07702435
- Testing
- Behavioral Intervention, Survey Administration
- Where
- United States
- Volunteers
- 607 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center