Clinical trials: Third Degree Burns
Burn; Multiple Body Regions, Max. Second Degree, Third-Degree Burn
Safety, Tolerability and Efficacy of Nefopam Cream in Burn Patients
Burn patients very commonly develop abnormal scars after injury which can be red, raised or elevated, painful and very itchy. They can prevent normal movement of hands and other joints and lead to ugly deformities which makes…
- Conditions
- Burn; Multiple Body Regions, Max. Second Degree, Third-Degree Burn, Burn Degree Second
- Trial name
- NCT04685577
- Testing
- Nefopam
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Burn Degree Second, Burn Degree Third
The Use of Cultured (Dermal) Epithelial Autografts in Severely Burned Patients
The Swisskera project is a multicenter follow-up study at the three Swiss burn centers evaluating long-term outcomes after burn wound coverage with lab-grown epithelial grafts, specifically cultured epithelial autograft (CEA)…
- Conditions
- Burn Degree Second, Burn Degree Third, Skin Transplantation, Full Thickness Skin Defects
- Trial name
- Swisskera (NCT07415577)
- Testing
- Standard of Care (SOC)
- Where
- 3 sites in Switzerland
- Volunteers
- 236 people
- Sponsor
- University Children's Hospital, Zurich
Burn Wounds, Third-Degree Burn Wounds
HUMSCs Combined With Col I to Third-Degree Burn Wound
To evaluate the safety and tolerability of human umbilical cord mesenchymal stem cells combined with bovine type I collagen in the treatment of third-degree burn wounds.
- Trial name
- NCT07530003
- Testing
- HUMSCs combined with bovine type I collagen, bovine type I collagen, Sterile blank dressing / Vaseline gauze
- Where
- China
- Volunteers
- 108 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Burn Any Degree Involving 20-29 Percent of Body Surface, Burn Any Degree Involving 30-39 Percent of Body Surface
Predictive Mortality Scales in the Burn Patient Admitted to the Intensive Care Unit
The data for this retrospective study were collected from the records of patients admitted to the intensive care unit (ICU) for burns at Hospital La Paz from January 1, 2019 to May 31, 2023.
- Conditions
- Burn Any Degree Involving 20-29 Percent of Body Surface, Burn Any Degree Involving 30-39 Percent of Body Surface, Burn Any Degree Involving 40-49 Percent of Body Surface, Burn Any Degree Involving 50-59 Percent of Body Surface
- Trial name
- NCT07526610
- Where
- Spain
- Volunteers
- 465 people
- Sponsor
- Universidad Rey Juan Carlos
Burns Degree Third, Burn (Disorder)
Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Burn Wounds as an Alternative to Autografting
To evaluate the safety and efficacy of realSKIN® to provide complete wound closure of mixed-depth, full-thickness burn wounds as an alternative treatment to autografting.
- Conditions
- Burns Degree Third, Burn (Disorder), Burn Degree Second, Thermal Burn
- Trial name
- NCT06223269
- Testing
- Skin Xenotransplant, Autograft(ing)
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- XenoTherapeutics, Inc.
Burns, Self Efficacy
Smartphone Assisted Self-management Education for Adult Burn Patient At Aftercare
Burn rehabilitation management is dependent on the patients themselves, non-treatment adherence may delay the optimal timing of burn rehabilitation and it may not be regained easily.
- Conditions
- Burns, Self Efficacy, Burn Second Degree, Burns Third Degree
- Trial name
- NCT06263296
- Testing
- Self Management Education
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Burn Wound, Second- or Third-degree Burn
MSCs for the Treatment of Burn Wounds
The goal of this study is to evaluate the capacity of allogenic mesenchymal stromal cells form bone marrow (BM-MSC) or adipose tissue(Ad-MSC) to induce wound healing in patients with burn wounds.
- Trial name
- NCT06103409
- Testing
- Implantation of allogeneic MSCs on burn wounds
- Where
- Venezuela
- Volunteers
- 50 people
- Sponsor
- Instituto Venezolano de Investigaciones Cientificas
Second-degree Burn, Third-Degree Burn
Manuka Honey in Second- and Grafted Third-degree Burns
Treatment strategies of II. degree burn wounds and split-skin grafted III. degree burn wounds aim at reducing infection and improving reepithelialization.
- Trial name
- NCT03048188
- Testing
- wound dressing
- Where
- 2 sites in Germany
- Volunteers
- 10 people
- Sponsor
- University Hospital Schleswig-Holstein
Split-skin Grafted Third-degree Burn Wound
Trial of Different Wound Dressings in Split-skin Grafted Third Degree Burns
In plastic and reconstructive surgery, treatment strategies of second-degree burn wounds and split-skin grafted third-degree burn wounds aim at reducing infection and improving reepithelialization.
- Trial name
- NCT03674151
- Testing
- Silver Nylon dressing, Manuka-Honey, Povidone-Iod (PVP-Iod)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Schleswig-Holstein
Burn Degree Second, Burn Degree Third
Biological Skin Graft With Keratinocyte-stem Cell Co-cultre for Burn Patients
The goal of this clinical trial is to test whether artificial skin graft can substitute autologous skin graft in current burn treatment.
- Trial name
- NCT05652816
- Testing
- Split-thickness skin graft, Artificial skin graft, Artificial skin graft co-culture
- Where
- Indonesia
- Volunteers
- 20 people
- Sponsor
- Universitas Indonesia
Second or Third Degree Burns
Hypoalbuminemia in Burn Patients
The purpose of this study is to determine whether 5% human albumin solution, given to correct hypoalbuminemia, could improve organ dysfunction in burn patients as assessed by a change in the SOFA score from baseline to day 7 (or…
- Trial name
- Halburns (NCT01436292)
- Testing
- 5% human albumin solution (HAS)
- Where
- Canada
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Burns, Ascorbic Acid Deficiency
Low Dose Vitamin C in Burns >20% Compared to Previous Studies With High Dose Vitamin C
Burn injury is marked by a large release of inflammatory mediators which disrupt the normal capillary barrier and cause a rapid shift of intravascular fluid into interstitial spaces, ultimately leading to shock and death.
- Conditions
- Burns, Ascorbic Acid Deficiency, Burn Shock, Burn Degree Second
- Trial name
- NCT05612867
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Arrowhead Regional Medical Center
Burn Degree Second, Burn Degree Third
The Effect of Reflexology Massage and Passive Music Therapy Intervention Before Burn Dressing
Reflexology massage applied before burn dressing reduces pain, anxiety and sleep problems
- Trial name
- NCT04200053
- Testing
- Reflexology massage, Reflexology massage and passive music
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Second or Third Degree Burns
Acute and Long-Term Outcome Investigations of Fenofibrate on Severely Burned Patients
The purpose of this study is to learn the following: whether long-term treatment (6 months) with fenofibrate will decrease burn related sugar and fat increased in the blood and help prevent muscle loss and improve wound healing.
- Trial name
- NCT01574131
- Testing
- Fenofibrate, Sugar Pill
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Third Degree Burn, Burns
StrataGraft™ Skin Tissue (Human Donor Skin) In The Surgical Management Of Complex Skin Defects
This pilot Phase I/II clinical study will be conducted at up to three clinical sites. This is an open-label, randomized, comparative study with a maximum of fifteen (15) patients, each with skin defects.
- Conditions
- Third Degree Burn, Burns, Wound Infection, Degloving Injury
- Trial name
- NCT00618839
- Testing
- StrataGraft Skin Tissue, Cadaver allograft
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Third Degree Burns, Diabetes
Study of ST266 in Diabetic Subjects With Deep Burns Managed With Skin Grafts
This study is a randomized, double blind, placebo controlled trial at a single site. The primary objective is to evaluate the safety of ST266 in diabetic subjects with deep burns.
- Trial name
- NCT01715012
- Testing
- ST266, Saline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Noveome Biotherapeutics, formerly Stemnion
Second- or Third-degree Burns
Allogeneic ADSCs and Platelet-Poor Plasma Fibrin Hydrogel to Treat the Patients With Burn Wounds (ADSCs-BWs)
The purpose of this study is to evaluate safety and efficacy of tissue engineered construct based on allogeneic cultured adipose-derived multipotent mesenchymal stromal cells (ALLO-ADSCs) and platelet-poor plasma fibrin hydrogel…
- Trial name
- ADSCs-BWs (NCT03113747)
- Testing
- ALLO-ASCs
- Where
- Ukraine
- Volunteers
- 20 people
- Sponsor
- A.A. Partners, LLC
Third Degree Burn, Second Degree Burn
Diagnostic of Infections Following Major Abdominal Surgery and Burn Injury
This study was designed to investigate, if new biomarkers may improve the early diagnostic of infections following major abdominal surgery and severe burn injuries.
- Trial name
- Earlygnost (NCT01055587)
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Klinikum St. Georg gGmbH
Third Degree Burns
Comparing Modified Meek and Mesh Techniques
This is a clinical trial study that compare two plastic surgery techniques in patients with third degree of burning and both techniques are used in all patients but in different areas of burning sites of the patients.
- Trial name
- NCT02285517
- Testing
- modified Meek skin grafting technique, mesh skin grafting technique
- Volunteers
- 20 people
- Sponsor
- Shahraki, Babak N., M.D.
Third Degree Burns
Askina Calgitrol Paste Burns
The purpose of the study is to demonstrate that Askina® Calgitrol® Paste is safe to use on III degree burns by quantifying the concentration of silver in the blood during treatment and thus to show that the amount of silver…
- Trial name
- NCT01911858
- Testing
- Askina Calgitrol Paste
- Sponsor
- BBraun Medical SAS