Clinical trials: Stoke
Anoxic Brain Injury
Safety and Efficacy Assessment of Autologous Bone-marrow Derived Adult Mesenchymal Stem Cell Therapy in Patients With Anoxic(or Hypoxic) Brain Injury Pilot Trial
The purpose of study is to evaluate the safety and efficacy of autologous bone marrow-derived stem cells therapy in patients with anaerobic (hypoxic) brain injury.
- Trial name
- NCT02210624
- Testing
- HYNR-CS inj.
- Where
- South Korea
- Volunteers
- 4 people
- Sponsor
- Hyun Young Kim
Acquired Brain Injury (Including Stroke)
Carer Involvement in Exercises for People With Acquired Brain Injury.
Increasing the amount of exercises completed has been shown to help recovery for people after a brain injury. This study will explore if providing extra training of exercises prescribed to a patient and carer team, will allow…
- Trial name
- NCT06952595
- Testing
- five exercises prescribed and taught to carers and participants
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Stroke, Gait Disorders, Neurologic
Most Effective Stimulation Site in Transcranial Direct Current Stimulation for Gait Recovery After Stoke
The aim of this study is to investigate the most effective stimulation site in transcranial direct current stimulation for gait recovery after stroke.
- Trial name
- NCT03460886
- Testing
- Ipsilesional stimulation, Contralesional stimulation, Walking on treadmill
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Samsung Medical Center
Stoke
Treating New Learning and Memory Deficits Following Stroke
The purpose of this research study is to investigate the effectiveness of a memory enhancement technique in persons following stroke
- Trial name
- NCT07127367
- Testing
- Memory Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kessler Foundation
Vascular, Stoke
Analysis of the Impact of the Fragility of the Over 70 Years of TIAprognosis
Fragility, geriatric concept recent identification is defined by simple physical indicators. The literature suggests that it is related to the risk of hospitalization, falls, institutionalization and death.
- Conditions
- Vascular, Stoke, Ischemic, Transient Ischemic Attack
- Trial name
- AIT70 (NCT02828488)
- Testing
- No intervention
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Atrial Fibrillation (AF), Stoke
Abbott Medical - VERITAS Study
The primary objective of this study is to evaluate the safety and effectiveness of Abbott's Amulet™ 2 Left Atrial Appendage (LAA) occluder device (Amulet 2 device) in patients who have non-valvular atrial fibrillation and who are…
- Trial name
- NCT06707688
- Testing
- Amulet™ 2 Left Atrial Appendage (LAA) Occluder
- Where
- 35 sites in United States, Belgium and 7 more
- Volunteers
- 458 people
- Sponsor
- Abbott Medical Devices
Cognitive Impairment, Dementia
Smartphone Multimodal Health Intervention for Neurological Enhancement (SHINE)
This randomized controlled trial will enroll individuals aged ≥ 40 years without dementia who are at high risk for stroke, collecting multi-modal MRI imaging, serum, and fecal samples to investigate the effects of a…
- Conditions
- Cognitive Impairment, Dementia, Artificial Intelligence (AI), Stroke
- Trial name
- NCT07092371
- Testing
- Digital Multimodal Intervention
- Where
- China
- Volunteers
- 1,036 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ischemic Stroke, Stroke
A Functional MRI Study: Assessing Brain Function in Post Stoke Patients
This is a prospective, single center, observational clinical study containing two cohorts the healthy cohort and post stroke cohort. A total of 13 subjects will be enrolled.
- Conditions
- Ischemic Stroke, Stroke, Acute Ischemic Stroke
- Trial name
- NCT06573840
- Testing
- NeuroGlove
- Volunteers
- healthy volunteers welcome
- Sponsor
- NeuroGlove LLC
Ischemic Stroke
Superselective Administration of VErapamil During Recanalization in Acute Ischemic Stroke
The purpose of this study is to determine whether super-selective intra-arterial administration of verapamil immediately following successful intra-arterial thrombolysis is safe as a potential neuroprotective agent.
- Trial name
- SAVER-I (NCT02235558)
- Testing
- Verapamil
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Justin Fraser
Stroke
Tele BCI-FES for Upper -Limb Stoke Rehabilitation
The study aims to identify whether stroke survivors can intentionally modulate their brain signals for controlling an FES device to produce arm movements for home based rehabilitation.
- Trial name
- NCT05215522
- Testing
- The BCI-FES Intervention
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Sheffield
Stroke
Clinical Efficacy of Exoskeleton Assistance for Individuals Post-Stroke
An exoskeleton device is a robotic system designed to improve an individual's ability to move and perform tasks encountered in everyday situations.
- Trial name
- NCT06064604
- Testing
- Control, Hip Exoskeleton, Ankle Exoskeleton
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Georgia Institute of Technology
Patent Foramen Ovale, PFO
The Effect of Device Closure of Patent Foramen Ovale in Elderly Patients With Crytogenic Stoke/TCI
The primary objective is to evaluate if patent foramen ovale (PFO) closure and antiplatelet medical management can reduce the risk of recurrent stroke or transient ischemic attack (TIA) when compared to antiplatelet medical…
- Conditions
- Patent Foramen Ovale, PFO, Stroke, TIA
- Trial name
- CryptoCard (NCT01018355)
- Testing
- Percutaneous device closure of patent foramen ovale
- Where
- Denmark
- Volunteers
- 3,000 people
- Sponsor
- Hillerod Hospital, Denmark
Hemiplegia
HEMITOX : Effect of Botulinum Toxin Injections on Motor and Functional Ability of Upper Limb in Adults at Earlier Phases of Spastic Hemiplegia After Stroke
Botulinum toxin produced beneficial effects in spasticity in the hemiplegic upper limb. This study will test if botulinum toxin injections at earlier phases (<or = 3 months) in spasticity improve functional and motor tests…
- Trial name
- NCT00276185
- Testing
- Time delay treatment of botulinum toxin
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cerebral Stroke, Thrombosis, Deep Vein
A Study of Adverse Events and Suspected Adverse Drug Reactions in Patients Under Apixaban for Prevention of Stroke and Systemic Embolism With Non-Valvular Atrial Fibrillation and Venous Thromboembolic Events in Patients Who Have Undergone Elective Hip or Knee Replacement Surgery
To characterize and analyze the number, type and incidence of adverse events/suspected adverse drug reactions in patients treated with Apixaban, according to therapeutic indications approved in Mexico.
- Conditions
- Cerebral Stroke, Thrombosis, Deep Vein, Pulmonary Embolism
- Trial name
- NCT03804125
- Sponsor
- Pfizer
Hemodynamic, Monitoring, Anesthesia
Pulse CONtour and BIoimpedance for Measurements of Stroke Volume During Changes in CARdiac Preload
Fluid therapy guided by stroke volume response to repeated fluid challenges is used for hemodynamic optimization during general anesthesia.
- Conditions
- Hemodynamic, Monitoring, Anesthesia, Blood Pressure
- Trial name
- ConBi-Car (NCT04231656)
- Testing
- CLEARSIGHT and NICCOMO measurements in sequence A, CLEARSIGHT and NICCOMO measurements in sequence B
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
Stroke
Virtual Reality Rehabilitation Protocol for Sensory-motor Rehabilitation After a Stoke
Introduction: Stroke is the second leading cause of death in Europe. In the case of stroke survival (almost 70%), only 25% of patients recover completely, while the remaining 75% will undergo a rehabilitation phase that varying…
- Trial name
- NCT06164054
- Testing
- Virtual Reality Rehabilitation System, Traditional therapy
- Volunteers
- 50 people
- Sponsor
- Sara Ventura
Acute Ischemic Stroke
"The Effect of Trimetazidine on the Clinical Outcome of Acute Ischemic Stroke Patients"
The investigators need to test the effect of Trimetazidine on the pro-inflammatory marker Interleukin - 18 , NIHSS score, and mRs score of acute ischemic stroke patients.
- Trial name
- NCT06656442
- Testing
- Trimetazidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Brain Ischemia,Stoke
Dyslipidemia Management in Chinese Post Stroke Patients
The purpose of this study is to provide current and reliable data of dyslipidimia management together with control situation of blood pressure and glucose for post-stroke patients within 6-12 months from attack, and also the…
- Trial name
- NCT01897883
- Where
- 26 sites in China
- Volunteers
- 5,000 people
- Sponsor
- AstraZeneca
Infarction, Middle Cerebral Artery
Thrombectomy Under Reopro Versus Alteplase to Treat Stoke
Intravenous (IV) Alteplase (rt-PA) is the gold standard for brain infarction within 4 h 30 of symptoms onset. Efficacy of this therapy is limited in the setting of large artery occlusions.
- Trial name
- TURANDOT (NCT02016547)
- Testing
- abciximab IV and thrombectomy, alteplase 0.9mg/kg (10% by IV bolus following by 90% by 1 hour IV drip)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- SOS Attaque Cérébrale
Stroke, Acute
Endovascular Acute Stroke Intervention Trial - the EASI Trial
Stroke constitutes the primary cause of acquired disability in adults and the second cause of dementia following Alzheimer disease.
- Trial name
- EASI (NCT02157532)
- Testing
- mechanical thrombectomy, Best standard treatment
- Where
- 2 sites in Canada
- Volunteers
- 480 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)