Clinical trials: Social Behaviour
Autism
Learning Enhancement Through Neurostimulation in Autism
This study will examine whether brain stimulation paired with social skills learning can help teenage boys with autism learn how to make and keep friends. Brain stimulation can enhance learning in some people.
- Trial name
- LENS (NCT02998684)
- Testing
- Active Transcranial Direct Current Stimulation, PEERS Social Skills Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Autism Spectrum Disorder
CPI Training for Parents of Children With ASD
The purpose of this 24-week study is to determine whether the "Parent-based Crisis Prevention Institute (CPI) physical management training program" (i.e., P-CPI) is effective in increasing self-efficacy in parents of children…
- Trial name
- NCT03537261
- Testing
- Parent-based Crisis Prevention Institute (CPI) physical management training program (P-CPI)
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Renal Transplant Rejection, Kidney Transplant Failure and Rejection
Envarsus on the Effect of Total Tacrolimus Dose/Trough Level Ratio on Renal Function (eGFR) in Kidney Transplantation
This is a one year, prospective, randomized, open-label trial examining once versus twice daily tacrolimus dosing regimen using two preparations, extended-release Tacrolimus (Envarsus XR) versus twice daily Tacrolimus (Prograf).
- Trial name
- NCT03511560
- Testing
- Tacrolimus Extended Release Oral Tablet, Tacrolimus
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Chronic Low Back Pain
Physical Activity Interventions To Heal Chronic Low Back Pain
This study will advance understanding on the mechanisms that mediate improved outcomes for chronic low back pain and provide specific directions for optimizing physical activity interventions for this population.
- Trial name
- PATH (NCT04678297)
- Testing
- Physical activity + emotion regulation intervention, Physical activity control intervention
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- University of Connecticut
Medication Adherence, High Blood Pressure
Social Forces to Improve Statin Adherence (Study B)
To assess the effectiveness of social comparison in improving the outcome of statin adherence versus usual care as measured by an electronic pill bottle.
- Conditions
- Medication Adherence, High Blood Pressure, Diabetes
- Trial name
- NCT02148523
- Testing
- Comparison to peers, Adherence feedback, Electronic pill bottle
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of Pennsylvania
Controlled Ovarian Stimulation
A Study to Assess the Efficacy and Safety of Ganirelix (Orgalutran®) Treatment in Chinese Women Undergoing Controlled Ovarian Stimulation for in Vitro Fertilization (IVF) or Intra Cytoplasmatic Sperm Injection (ICSI) (Study 38651)(P05703)
The primary purpose of this study is to assess that ganirelix is safe and well-tolerated in Chinese women and that a controlled ovarian stimulation (COS) protocol combining recombinant follicle stimulating hormone (recFSH) with…
- Trial name
- NCT00725491
- Testing
- ganirelix, triptorelin
- Volunteers
- 259 people
- Sponsor
- Organon and Co
Alcohol Drinking
Neural and Behavioral Effects of Cognitive Bias Modification (CBM)
This study seeks to better understand mechanisms of behavior change for heavy drinkers who are interested in changing their drinking.
- Trial name
- NCT04430543
- Testing
- Cognitive Bias Modification
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston University Charles River Campus
Hiv, HIV Infections
Standardized Patients to Measure and Address Intersectional Stigma
This study aims to develop and evaluate an intervention to reduce enacted stigma in healthcare settings aimed at people living with HIV (PLWH) and men who have sex with men (MSM) in China.
- Conditions
- Hiv, HIV Infections, AIDS
- Trial name
- NCT04896216
- Testing
- Stigma Reduction Intervention
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Minnesota
Hiv, Stigma, Social
Buddhist Understanding and Reduction of Myanmar Experiences of HIV Stigma and Exclusion
This project aims to explore a multi-leveled conceptualization of the effects of HIV stigma on HIV care engagement in Myanmar by conducting a mixed-method study.
- Conditions
- Hiv, Stigma, Social, Mindfulness
- Trial name
- BURMESE (NCT05126225)
- Testing
- Stigma reduction
- Where
- 2 sites in Burma, Thailand
- Volunteers
- 19 people
- Sponsor
- University of California, Los Angeles
Autism, Asperger's Syndrome
Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism spectrum disorders affect as many as 1 out of 88 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01919970
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism
Oxcarbazepine Versus Placebo in Childhood Autism
The proposed study is designed to assess the effectiveness of treatment with Oxcarbazepine vs. placebo in childhood/adolescent autism.
- Trial name
- NCT00467753
- Testing
- Oxcarbazepine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Caregivers, Decision Making
"Safety in Dementia": An Online Caregiver Intervention
In an online randomized trial of Safety in Dementia with national recruitment and longitudinal follow-up, we will recruit informal caregivers of community-dwelling adults with dementia who have firearm access.
- Conditions
- Caregivers, Decision Making, Alzheimer Disease, Social Media
- Trial name
- NCT05173922
- Testing
- Safety in Dementia
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Rheumatoid Arthritis, Cardiovascular Diseases
Cardiovascular Risk Assessment for Patients With Rheumatoid Arthritis Arthritis:
One of the greatest success stories in rheumatology - the achievement of rheumatoid arthritis (RA) remission - is tempered by the fact that individuals with RA are dramatically under evaluated and under treated to reduce the risk…
- Conditions
- Rheumatoid Arthritis, Cardiovascular Diseases, Hyperlipidemias
- Trial name
- CARE RA (NCT04488497)
- Testing
- Cardiovascular Risk Assessment for Patients with Rheumatoid Arthritis, Standard of care
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Interdisciplinary Communication, Management, Medication Therapy
Minimizing Harm From ADEs by Improving Nurse-Physician Communication
The purpose of this research study is to examine the clinical processes of care involved with the sharing and communicating of medication management information in the inpatient setting between nurses, pharmacists and physicians.
- Trial name
- MED-COMM (NCT00574990)
- Where
- 3 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Infertility, Ovarian Stimulation
A Prospective Study to Evaluate the Addition of Subcutaneous Recombinant Human-Luteinizing Hormone With Recombinant Human-Follicle Stimulating Hormone on Follicular Development in Women Undergoing Ovarian Stimulation for Assisted Reproductive Technologies
In-vitro fertilization (IVF) of human oocytes followed by the replacement of embryo in the uterine cavity has become a well established treatment for female infertility attributable to damaged fallopian tubes, endometriosis or…
- Trial name
- NCT01121991
- Testing
- Recombinant Human-Luteinizing Hormone (Luveris)
- Volunteers
- 55 people
- Sponsor
- EMD Serono
Breastfeeding, SUID
Social Media and Risk Reduction Teaching-Enhanced Reach
This study aims to improve adherence to American Academy of Pediatrics safe sleep (SS) recommendations and improve rates of initiation and duration of partial and exclusive breastfeeding (BF) through direct education of mothers…
- Conditions
- Breastfeeding, SUID, SIDS
- Trial name
- SMARTER (NCT04387552)
- Testing
- Prenatal Safe Sleep Mobile Health (mHealth) Messaging, Prenatal Breastfeeding Mobile Health (mHealth) Messaging, Postnatal Safe Sleep Mobile Health (mHealth) Messaging
- Where
- United States
- Volunteers
- 2,093 people
- Sponsor
- Boston University
Cognitive Impairment, Mild, Cognitive Decline
Efficacy of a Multimodal Brain Health Intervention for Older African Americans
This study tests the feasibility, acceptability, and efficacy of a multimodal intervention (walking, social engagement, and reminiscence), including the use of wearable digital biomarkers, for cognitively healthy and mildly…
- Trial name
- SHARP (NCT04863378)
- Testing
- Walking conversational reminiscence
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Alcohol Consumption, Violence, Domestic
Proximal Effects of Alcohol on Same-Sex Intimate Partner Violence
We will recruit sexual and gender minority couples to complete 56 days of daily surveys in order to evaluate (1) the impact of COVID-19 stress and sexual and gender minority stress on heavy episodic drinking and intimate partner…
- Conditions
- Alcohol Consumption, Violence, Domestic, Stress, Psychological, Aggression
- Trial name
- PASSION (NCT04625465)
- Testing
- CBT Text Messaging, Attention Control Text Messaging
- Where
- United States
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Sleep Apnea, Obstructive, Patient Compliance
Tailored Intervention to Promote Positive Airway Pressure Adherence
The purpose of this study is to examine the feasibility of a tailored (i.e., individualized) intervention to promote adherence to continuous positive airway pressure therapy (CPAP) in adults with newly-diagnosed, CPAP treated…
- Trial name
- SCIP-PA (NCT01454830)
- Testing
- Tailored, Usual care
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Milton S. Hershey Medical Center
Loneliness, Social Isolation
Engage Psychotherapy to Promote Connectedness in Caregivers
The Engage Coaching Project is a Stage 1 intervention development study. This study asks: "what behavioral strategies are needed to help socially disconnected caregivers with significant barriers to increasing connectedness?"…
- Conditions
- Loneliness, Social Isolation, Caregiver Burnout
- Trial name
- NCT04176601
- Testing
- Engage coaching
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Rochester