Clinical trials: Refractive Errors
Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser on an Implanted Intraocular Lens
This is a prospective non-randomized patient controlled single center study which is designed to evaluate the clinical outcomes of the treatment of an implanted intraocular lens using a low-energy femtosecond laser for refractive…
- Trial name
- NCT07473557
- Testing
- Device
- Where
- Panama
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Refractive Errors
Morphological Characteristics of the Maxillomandibular Region in a 3D Representation and the Refractive Status of the Eye
The goal of this observational study is to learn more about the relationship between the size and shape of the eye and the shape of the face in healthy young adults.
- Trial name
- NCT07460557
- Testing
- No intervention; Observational study
- Where
- Croatia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Near Vision, Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser Treatment in a Patient With Implanted Monofocal IOLs
This study aims to assess the safety and efficacy of evaluating near vision or refractive error in eyes implanted with a mono focal intraocular lens (IOL) using a low-energy femtosecond laser.
- Trial name
- NCT07447622
- Testing
- Device
- Where
- Czechia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Myopia, Myopia; Refractive Error
Peripheral Relative Refractive Power of Orthokeratology Lenses
Orthokeratology (OK) has been demonstrated to be an effective intervention for slowing axial elongation in children with myopia.
- Trial name
- NCT07294404
- Testing
- orthokeratology
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Presbyopia, Pseudophakia
Visual Outcomes After Extended Depth of Focus Intraocular Lens Implantation With and Without Digital Assistance
The primary objective of this study is to compare the postoperative visual acuity curves of patients that underwent one of the following surgical procedures: Insertion of an extended depth of focus intraocular lens with digital…
- Conditions
- Presbyopia, Pseudophakia, Cataract, Refractive Errors
- Trial name
- NCT06460389
- Testing
- Visual Acuity Assessment
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Myopia, Progressive
Stellest Lens Wear in Adult Progressing Myopes
It is expected that myopia progression stabilises in the late teenage years, however, some studies report that myopia progression continues through early adulthood in as many as one third of myopes.
- Trial name
- SWAP (NCT06520124)
- Testing
- Essilor® Stellest® spectacle lens, Single-vision spectacle lens
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Myopia, Ametropia
LED Low-Intensity Red Light for Myopia Control in Youth: Efficacy and Safety Study
The purpose of this clinical trial was to investigate the efficacy and safety of repetitive low-intensity single-wavelength red light from an LED light source in controlling myopia progression in children and adolescents.
- Trial name
- NCT07375589
- Testing
- Red light treatment with 1.6mW LED light source, Red light treatment with 0.001mW LED light source
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Refractive Error
A Non-Treatment Clinical Evaluation of the ELITA Single Piece Patient Interface for Docking Procedure With the ELITA
Open label, prospective, randomized, multicenter, measurement only feasibility study to evaluate the docking procedure using the ELITA Single Piece Patient interface in conjunction with the ELITA system
- Trial name
- NCT06727799
- Testing
- Docking Assessment / Observation
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Visual Acuity, Refractive Errors
Assessing the Turkish DDIVAT for Visual Acuity Measurement
The goal of this observational methodological study is to validate the Turkish version of the DDIVAT visual acuity measuring device in a Turkish-speaking adult population.
- Conditions
- Visual Acuity, Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT07240480
- Testing
- DDIVAT Visual Acuity Test (Turkish Version)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Trakya University
Refractive Errors, Cataract
Xinxing Eye Cohort Study
To establish the baseline levels and monitor the progress of two newly introduced global eye health indicators in Xinxing County, including effective refractive error coverage (eREC) and effective cataract surgery coverage…
- Trial name
- NCT07257536
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Refractive Errors
Measurment of Optic Disc Parameters, RNFL Thickness and Ganglion Cell Complex in Myopic, Hypermetropic and Emmetropic Patients Using OCT and Axial Length Measurments
To evaluate the optic disc parameters, thickness of ganglion cell complex (GCC), and thickness of peripapillary retinal nerve fiber layer (RNFL) in myopic and hyperopic and emmetrop patients using optical coherence tomography…
- Trial name
- NCT07241806
- Testing
- OCT
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Assiut University
Visual Impairment, Refractive Error
Frequency of Visual Impairment Among School Children and Effectiveness of mHealth Referral Reminder on Uptake of Referral Services
This study tested whether mobile health (mHealth) tools can affect referral uptake among schoolchildren with vision problems.Visual impairment in children often goes untreated in low- and middle-income countries, even when…
- Trial name
- NCT06616051
- Testing
- Multicomponent SMS reminder
- Where
- Pakistan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Syed Fawad Mashhadi
Refractive Error - Myopia Bilateral
Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens
This clinical study is to provide clinical performance data comparing the test lens (Deseyne [vifilcon C] daily disposable soft contact lens) to a control lens (1-Day Acuvue Moist [etafilcon A] daily disposable soft contact lens)…
- Trial name
- NCT05927753
- Testing
- Deseyne Daily Disposable Contact Lens (Test Device)
- Where
- 3 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Bruno Vision Care
Myopia, Light; Therapy, Complications
Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN)
The goal of this clinical trial is to evaluate whether the optimization of daily exposure to light in primary school children can lead to better myopia prevention and control.
- Conditions
- Myopia, Light; Therapy, Complications, Myopia Progression, Short-Sighted
- Trial name
- LightSPAN (NCT06631339)
- Testing
- Light Intervention, Digital Intervention, Control Group
- Where
- 5 sites in Singapore
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Myopia
Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial
This is a multi-center, randomized, double-masked clinical trial. All study devices are market approved/cleared in the localities where the study is conducted.
- Trial name
- PROTECT (NCT05159765)
- Testing
- Single vision contact lenses, Multifocal contact lenses
- Where
- 8 sites in United States, Canada and 2 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Refractive Error Correction
SUBJECTIVE REFRACTION WITH LIGHTFIELD TECHNOLOGY
The aim of this study is to test whether it is possible in principle to determine defective vision using light field technology.
- Trial name
- NCT06583954
- Where
- 2 sites in Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Daniela Nosch
Presbyopia
Evaluation of Safety and Efficacy of Intrastromal Implantation of CorVision® Bioengineered Corneal Inlay for Correction of Presbyopia.
This clinical investigation is a prospective, multicentre, non-comparative case series to assess safety and efficacy of CorVision® bioengineered corneal inlay for improving uncorrected near vision in presbyopic subjects.
- Trial name
- CorVision (NCT04465409)
- Testing
- Intrastromal implantation of CorVision bioengineered corneal inlay for correction of presbyopia.
- Where
- Czechia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- LinkoCare Life Sciences AB
Glaucoma, Diabetic Retinopathy (DR)
"My Eyes, My Light": Amar Chokh, Amar Alo
Eye disease affects 2.2 billion people globally, which in turn adversely affects schooling, economic productivity, and participation in social life.
- Conditions
- Glaucoma, Diabetic Retinopathy (DR), Hypertensive Retinopathy, Cataract
- Trial name
- ACA2 (NCT07135570)
- Testing
- Multimodal Screening for Eye Disease, cataract surgery
- Where
- Bangladesh
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Data Yakka, Inc.
Amblyopia, Refractive Errors
The Effect of Early Glasses on the Development of Amblyopia
In a randomized controlled trial, we will establish whether early glasses for high refractive error at age one reduce the development of amblyopia between age one and four.
- Trial name
- EGS (NCT04740593)
- Testing
- Orthoptic care with the prescription of glasses from age 12-18 months onwards, Orthoptic care without the prescription of glasses from age 12-18 months onwards, First measurement only
- Where
- Netherlands
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Glaucoma, Diabetic Retinopathy
Providing Financial Incentives to Improve Adherence to Referral Eye Care Visits
Glaucoma is a blinding eye disease increasingly common in older adults, particularly in African Americans, and often diagnosed late in the disease course.
- Conditions
- Glaucoma, Diabetic Retinopathy, Refractive Errors, Cataract
- Trial name
- AL-SIGHT (NCT04328207)
- Testing
- No Financial Incentive, Financial Incentive
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham