Refractive Error CorrectionNCT06583954
SUBJECTIVE REFRACTION WITH LIGHTFIELD TECHNOLOGY
An observational study of Refractive Error Correction, run by Daniela Nosch at 2 sites in Switzerland.
Trial summary
The aim of this study is to test whether it is possible in principle to determine defective vision using light field technology. The measurements with this first prototype will be compared with the results of the conventional method for subjective refraction determination and those using a phoropter (Vision R-800… Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Refractive Error Correction
- How many people
- 120 participants
- Where
- 2 sitesSwitzerland
- Study dates
- 15 Feb 2025to 30 Aug 2025
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: healthy adults with refractive error
Who may be able to join
- Minimum age of 18 years
- Best corrected visual acuity ≥ 0.8 (logMAR ≤ 0.1).
- Dioptric range for hypermetropia: ≤ +4.50 D.
- Dioptric range for myopia: ≥ -6.50 D.
- Dioptric range for cylinder: ≤ -2.00 D.
- Good general health, i.e.no systemic disease such as diabetes or rheumatism which could influence ocular health
- No ocular pathology or history of (intra)ocular surgery except for cataract surgery
Who cannot join
- • Contact lens wear during the days of visit
- Binocular vision problems (e.g. amblyopia, strabismus).
- Inability to follow the procedures of the investigation, such as language problems, psychological disorders and dementia
Trial locations and contacts
2 sites in 1 country.
Switzerland2 sites
Institute of Optometry, FHNW
Olten, Canton of Solothurn, 4600
Insititute of Optometry, FHNW University of Applied Sciences and Arts Northwestern Switzerland
Olten, 4600
About this study
Official title: PROOF OF CONCEPT OF A NEW DEVICE FOR SUBJECTIVE REFRACTION WITH LIGHTFIELD TECHNOLOGY
The aim of this study is to test whether it is possible in principle to determine defective vision using light field technology. The measurements with this first prototype will be compared with the results of the conventional method for subjective refraction determination and those using a phoropter (Vision R-800 phoropter).
- Conditions
- Refractive Error Correction
- Keywords
- subjective refraction, phoropter, lightfield technology
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| healthy adults with refractive error | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
precision of determination of refractive error
To explore if this prototype CREAL device based on LightField Technology can determine the refractive error reliably, in comparison to well-established methods such as subjective refraction with a trial frame and with the phoropter Vision-R 800 (Essilor SA).
Measured: within one week
Secondary outcomes (1)
repeatability of all three methods for subjective refraction
Measured: within one week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Sep 2024
- Study start15 Feb 2025
- Primary completion30 May 2025
- Study completion30 Aug 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Refractive Error CorrectionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 120 participants (actual)
Sponsor and investigators
- Lead sponsor
- Daniela Nosch
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Daniela Nosch, University of Applied Sciences and Arts Northwestern Switzerland
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06583954
- Sponsor's protocol ID
- 2024-D0081
- Other IDs
- 2024-D0081
- Status last verified
- Sep 2025
- First submitted
- 2 Sep 2024
- Last updated
- 5 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Venkataraman AP, Sirak D, Brautaset R, Dominguez-Vicent A. Evaluation of the Performance of Algorithm-Based Methods for Subjective Refraction. J Clin Med. 2020 Sep 29;9(10):3144. doi: 10.3390/jcm9103144.
PubMed 33003297