Clinical trials: Presbyopia
Presbyopia
Performance of Two Daily Disposable Multifocal Contact Lenses
This study will compare the performance of two daily disposable multifocal soft contact lenses.
- Trial name
- NCT07444658
- Testing
- Lens A (kalfilcon A), Lens B (stenfilcon A)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- CooperVision International Limited (CVIL)
Presbyopia
Contact Lens Trial Fitting Experience
This study will assess a trial fitting experience with contact lenses.
- Trial name
- NCT07600645
- Testing
- Lens A ( stenfilcon A )
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- CooperVision International Limited (CVIL)
Aphakia, Presbyopia
Post Market Clinical Evaluation of Clareon PanOptix Pro and Clareon PanOptix Pro Toric IOLs
The purpose of this study is to collect safety and performance data on two approved intraocular lenses (IOLs). This study will be conducted in participants who require cataract surgery in both eyes.
- Trial name
- NCT07161635
- Testing
- Clareon PanOptix Pro/Pro Toric Trifocal IOL, Phacoemulsification
- Where
- 5 sites in United States
- Volunteers
- 110 people
- Sponsor
- Alcon Research
Presbyopia
Evaluation of Functional Superiority of the Morrow eProgressive
Presbyopia is a common age-related condition where the eye loses its ability to focus on nearby objects, typically from around age 45.
- Trial name
- EPACT (NCT07878416)
- Testing
- 3 weeks wearing of study device instead of their current wearing solution
- Where
- 3 sites in Belgium, Italy
- Volunteers
- 50 people
- Sponsor
- Morrow Eyewear
Presbyopia, Ametropia
Clinical Trial With Artiflex Presbyopic (Artiplus)
The purpose of this clinical trial is to evaluate the effectiveness and safety of the multifocal Artiflex Presbyopic (Artiplus) intraocular lens.
- Conditions
- Presbyopia, Ametropia, Refractive Errors, Myopia
- Trial name
- NCT04632784
- Testing
- Artiflex Presbyopic (Artiplus) implantation
- Where
- 7 sites in South Korea, Spain
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Ophtec BV
Visual Acuity, Presbyopia
Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses
This is a 6-visit, single-masked, multi-site, 2×3 crossover, randomized-controlled, dispensing clinical trial to evaluate visual acuity.
- Trial name
- NCT07076160
- Testing
- INFUSE® One Day Multifocal, ACUVUE® OASYS MAX 1-Day Multifocal Contact Lens
- Where
- 7 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Volumetric Visual Fields at Intermediate and Near Distances in Presbyopic Patients Using Occupational and General-Purpose Progressive Addition Lenses
This single-center, randomized, double-blind, crossover clinical trial aims to compare the volumetric visual fields provided by two occupational progressive addition lenses (OPLs) optimized for intermediate and near vision in…
- Trial name
- CIVIUS2025PAL (NCT07617090)
- Testing
- OPAL PC assesment, OPAL Office assessment, PAL assesment
- Where
- 2 sites in Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Seville
Presbyopia
VisDura VisAbility™ Micro Insert System Pre-market Clinical Trial
The primary study objective is to evaluate the safety and effectiveness of the VisAbility™ Micro Insert System for improvement in binocular distance corrected near visual acuity in presbyopic patients.
- Trial name
- NCT07637500
- Testing
- VisAbility™ Micro Insert System
- Where
- 2 sites in Germany
- Volunteers
- 33 people
- Sponsor
- VisDura, Inc.
Presbyopia
Volumetric Visual Fields at Different Distances in Presbyopic Patients Using Occupational (PC-133 and PC-200) and General-Purpose Progressive Addition Lenses
This single-center, randomized, double-blind, crossover clinical trial aims to compare the volumetric visual fields provided by two occupational progressive addition lenses (OPLs) optimized for intermediate and near vision in…
- Trial name
- CIVIUS2026PAL (NCT07870785)
- Testing
- OPAL PC 133 assessment, OPAL PC 200 assessment, PAL assessment
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- University of Seville
Aphakia, Presbyopia
Contralateral Claims Study of Clareon Vivity Pro
The purpose of this study is to test new versions of Clareon Vivity Pro intraocular lenses (IOLs) by comparing them to currently marketed IOLs.
- Trial name
- NCT07484191
- Testing
- Clareon Vivity Pro IOL, Clareon Vivity IOL, TECNIS PureSee IOL
- Where
- 7 sites in Australia
- Volunteers
- 165 people
- Sponsor
- Alcon Research
Keratoconus, Presbyopia
Proof-of-Concept for a Novel Optical Aperture Contact Lens in Presbyopia and Keratoconus
The purpose of this clinical study is to evaluate the effectiveness of the NOA lens, a custom-made scleral contact lens developed by Azalea Vision BV, in improving visual quality for individuals with keratoconus and presbyopia.
- Conditions
- Keratoconus, Presbyopia, Scleral Contact Lenses, Pinhole
- Trial name
- NOA (NCT07559188)
- Testing
- NOA lens type 1, NOA lens type 2
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 16 people
- Sponsor
- Azalea Vision
Presbyopia, Near Vision
Phase 3 Efficacy Study of LNZ100 & LNZ101 for the Treatment of Presbyopia
Phase 3 Efficacy Study to evaluate the Safety and Efficacy of LNZ100 \& LNZ101 for the Treatment of Presbyopia
- Conditions
- Presbyopia, Near Vision, Refractive Error, Eye Diseases
- Trial name
- CLARITY 2 (NCT05728944)
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle
- Where
- 17 sites in United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Presbyopia Correction, Presbyopia
Clinical Evaluation of Visual Performance, Spectacle Independence, and Patient Satisfaction With TECNIS PureSee Mini-Monovision and TECNIS PureSee-TECNIS Odyssey Mix-Match
The purpose of the study is to evaluate the binocular clinical endpoints of distance, intermediate, and near vision and patient reported outcomes utilizing mini-monovision versus mix-match approaches for the correction of…
- Conditions
- Presbyopia Correction, Presbyopia, Dysphotopsia, Visual Acuity
- Trial name
- NCT07860567
- Testing
- TECNIS PureSee IOL (Model DEN00V/DET150), TECNIS Odyssey IOL (Model DRN00V/DRT150)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Dr. Daniel H. Chang, MD
Presbyopia Correction, Presbyopia
Presbyopic Wear Experience With Multifocal Lenses Compared to Single Vision Lenses and Reading Glasses
The purpose of the study is to assess participant experience when wearing multifocal contact lenses compared to spherical contact lenses with reading glasses.
- Trial name
- NCT07218731
- Testing
- Multifocal contact lenses, Spherical contact lenses
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Intraocular Lens, Cataract
Evaluation of Safety and Effectiveness of an IOL With a Virtual Aperture Optic
Cataracts are cloudy areas in the lens of the eye that can cause changes in vision. Symptoms of cataracts include cloudy or fuzzy vision and sensitivity to glare.
- Conditions
- Intraocular Lens, Cataract, Presbyopia
- Trial name
- NCT05955846
- Testing
- cataract surgery, implantation of device IOL FG-80030.1
- Where
- 8 sites in Portugal, Spain and 1 more
- Volunteers
- 60 people
- Sponsor
- Z Optics, Inc.
Multiple Sclerosis, Dry Eye Syndromes
Clinical Applications of Advanced Ophthalmic Imaging
The purpose of this study is to determine the clinical application of advanced ophthalmic imaging devices such as optical coherence tomography (OCT), retinal function imager (RFI), slit-lamp biomicroscopy (SLB), PERG in diseased…
- Conditions
- Multiple Sclerosis, Dry Eye Syndromes, Diabetic Retinopathy, Presbyopia
- Trial name
- NCT03135327
- Testing
- Ocufolin
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Miami
Myopia, Presbyopia
Comfort and Vision With TOTAL30 Multifocal Lenses
This study is a single-arm, prospective, observational study conducted at one site to evaluate the comfort and vision of the TOTAL30 Multifocal (T30MF) contact lenses over the course of long wear days.
- Conditions
- Myopia, Presbyopia, Astigmatism
- Trial name
- NCT07284966
- Testing
- TOTAL30 Multifocal
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Scripps Poway Eyecare and Optometry
Aphakia, Astigmatism
Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix
The purpose of this Post-Market Clinical Follow-up study is to describe the long-term safety and performance of the Clareon Vivity and Vivity Toric and Clareon PanOptix and PanOptix Toric IOLs.
- Conditions
- Aphakia, Astigmatism, Presbyopia
- Trial name
- NCT05796453
- Testing
- Clareon Vivity IOL - Non Toric, Clareon Vivity IOL - Toric, Clareon PanOptix Trifocal IOL - Non Toric
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 470 people
- Sponsor
- Alcon Research
Presbyopia
Evaluate the Efficacy and Safety of CTO0307 in Adults With Presbyopia
This study was to compare the presbyopia correction effect between the treatment group and the control group, evaluated by the proportion of patients who achieved an improvement of 3 lines or more in mesopic binocular DCNVA at…
- Trial name
- NCT07723716
- Testing
- CTO0307 Eye drop
- Where
- South Korea
- Volunteers
- 167 people
- Sponsor
- Taejoon Pharmaceutical Co., Ltd.
Presbyopia
PROductivity Study of Presbyopia Elimination in Rural-dwellers II
The investigators will conduct a randomized-controlled trial. The participants will be textile workers aged 35 years and above with uncorrected presbyopia who are employed by a single Indian garment manufacturer - employed by…
- Trial name
- PROSPERII (NCT04629820)
- Testing
- Spectacles
- Where
- India
- Volunteers
- 682 people
- Sponsor
- Queen's University, Belfast