Clinical trials: Post-burn Scars
Hypertrophic Scar
Effect of Silicone Gel Versus Contractubex Phonophoresis for Post-burn Hypertrophic Scars
Hypertrophic scars and keloids are physically and mentally disturbed, and in addition, can cause pain and itching. Various treatment is utilized to diminish or counteract scarring.
- Trial name
- NCT03777891
- Testing
- phonophoresis with different material
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Burn Injury, Acute Wound
Cutaneous Microcirculation After Plasma Therapy
In plastic and reconstructive surgery, treatment strategies of second-degree burns, superficial wounds, burn scars, flaps and chronic wounds aim at reducing infection and improving microcirculation.
- Conditions
- Burn Injury, Acute Wound, Chronic Wound, Burn Scar
- Trial name
- NCT02417818
- Testing
- Plasma Therapy (PlasmaDerm), Repetitive Plasma Therapy (repetitive PlasmaDerm)
- Where
- Germany
- Volunteers
- 240 people
- Sponsor
- University Hospital Schleswig-Holstein
Post-burn Innervation
Study of the Cutaneous Reinnervation After Burn
The aim of this study is to understand why the regeneration of the cutaneous sensory nerve fibers is poor in post-burn scar. The presence or the lack of several molecular factors known to regulate neuronal cell development will…
- Trial name
- NERVAL (NCT02356354)
- Testing
- Skin biopsy
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Brest
Joint Contracture, Contracture
Recurrence of Extremity Joint Contracture After Z-Plasty Versus Full-Thickness Skin Graft
The purpose of this study is to compare how often joint contractures in the arms and legs come back after two common types of reconstructive surgery: Z-plasty and full-thickness skin graft (FTSG).
- Conditions
- Joint Contracture, Contracture, Cicatrix, Burn Scar Contractures
- Trial name
- NCT07885046
- Testing
- Z-Plasty, Full-Thickness Skin Graft
- Volunteers
- 300 people
- Sponsor
- Universitas Sebelas Maret
Burns, Scar Pruritus
Exploring the Correlation Between Post Traumatic Stress Disorder, Perceived Stress and Scar Pruritus in Burn Patients
Pruritus, post traumatic stress disorder and perceived stress are common issues in burn patients. The correlation between the three is unclear so far.
- Conditions
- Burns, Scar Pruritus, Post Traumatic Stress Disorder, Perceived Stress
- Trial name
- NCT05885321
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- National Taiwan University Hospital
Burn Scar
Tolerance Assessment of Tailored 3d-printed TFO With Silicone Interface for the Treatment of Post-burn Face Scar
The purpose of this study is to assess the tolerance of tailored 3d-printed transparent face orthosis used in the medical care of post-burn face scar.
- Trial name
- ECORCE (NCT04884789)
- Testing
- COFIS 3D
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Romberg Disease, Craniofacial Microsomia
Efficacy of Preconditioned Adipose-Derived Stem Cells in Fat Grafting
The aim of this study is to evaluate the comparison of therapeutic potential of curcumin preconditioned adipose derived stem cells (ASCs) enrichment fat grafting, naïve ASCs enrichment fat grafting and conventional fat grafting…
- Conditions
- Romberg Disease, Craniofacial Microsomia, Burn Scar, Post-Traumatic Scar (Disorder)
- Trial name
- NCT05610878
- Testing
- Cultured ASCs enrichment fat grafting, Curcumin-preconditioned ASCs enrichment fat grafting, Conventional fat grafting
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- University of the Punjab
Post Surgical Scars, Epidermic Burn
Cicatrix Cream in Post Surgical Scars and Epidermic Burn
The purpose of the study is to assess the effect of CICATRIX (Asian Gotu Kola or Pennywort) usage in the treatment of epidermic burns or post surgical scars. The duration of this phase 2 clinical trial will be two months.
- Trial name
- NCT01018589
- Testing
- Cicatrix cream
- Where
- Cuba
- Volunteers
- 100 people
- Sponsor
- Catalysis SL
Burn Scar
Comparison of Length Gain Between Square Flap and Z-plasty in Post Burn Contracture Release
the purpose of this study is to compare the gain in length after postburn contracture release using two different techniques, the more commonly practised z - plasty and relatively newer technique, square flap
- Trial name
- NCT04690543
- Testing
- z-plasty, square flap
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Cicatrix, Hypertrophic
The Effect of Extracorporeal Shock Wave Therapy in the Treatment of Post Burn Scars
A prospective, randomized, controlled study. The patients were divided into two groups with twenty patients per group. The control group received the standard treatment for postburn scars.
- Trial name
- NCT04558944
- Testing
- Extracorporal Shock Wave Therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Burn Scar Pain, Neuropathic Pain
Ultrasound Predictors of Persistent Burn Scar Pain After Blast and Drone-Related Injuries: A Prospective Cohort Study
Persistent burn scar pain is common after blast and drone-related injuries and may be driven by scar fibrosis, vascular activity, and peripheral nerve involvement within scar tissue.
- Conditions
- Burn Scar Pain, Neuropathic Pain, Combat-Related Burn Injury, Scar-Related Pain
- Trial name
- US-SCAR-PAIN (NCT07438769)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Burn Scar
Nanofat in Post Burn Scars on the Face
Quasi-Experimental Study: Unfiltered Nanofat Injected into Postburn Facial Scars Number of Patients: 48 Outcome Assessed on POSAS And with Imaje J Scanning Preop And Postop Statistical Comparison of Scar Done
- Trial name
- NCT03352297
- Testing
- Unfiltered Nanofat Graft
- Volunteers
- 48 people
- Sponsor
- King Edward Medical University
Burns, Hypertrophic Scar
Differential Pressure Distribution Orthosis by 3D Printing Process in the Treatment of Post-burn Hypertrophic Scarring
This is a pilot, single-center, feasibility study to evaluate a new 3D printing method for ORDP design. To our knowledge, there is no technical or clinical evaluation of ORDPs, particularly in the treatment of hypertrophic scars.
- Trial name
- EPIDERM (NCT06487910)
- Testing
- 3D scan measurment
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Scar Conditions and Fibrosis of Skin, Scar Quality Assessment and Safety
Scar Remodeling After Burn Injury Using Allogeneic Adipose-derived Stromal Cells
The present project serves to test whether stem cell therapy offers a new treatment option for the scars of burn survivors. In Denmark, 12.000 people seek medical assistance every year for burn injuries leaving thousands of…
- Conditions
- Scar Conditions and Fibrosis of Skin, Scar Quality Assessment and Safety, Scar Tissue
- Trial name
- ScarASC (NCT07635875)
- Testing
- Allogeneic adipose-Derived Mesenchymal Stromal Cells, Cryostor CS10 + Ringers Lactate
- Where
- Denmark
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hypertrophic Scar, Burn Scar (Post-burn)
COMPARISON STUY OF KINESIOTAPE AND LOW-LEVEL LASER THERAPY ON HYPERTROPHIC SCAR
Hypertrophic scars after burn injury often cause pain, stiffness, and cosmetic concerns. Kinesio taping (KT) and low-level laser therapy (LLLT; photobiomodulation) are widely used, yet direct comparisons and combined-therapy data…
- Conditions
- Hypertrophic Scar, Burn Scar (Post-burn), Burns
- Trial name
- NCT07209891
- Testing
- Kinesio Tape, Low-Level Laser Therapy (LLLT), 905-nm pulsed Ga-As, Standardized Scar Care (concomitant for all arms)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Burn
Hypertrophic Scarring After Facial Burn
Subjects with a burn to the face and/or neck will be enrolled into the study and a Three-Dimensional scanner used to see if it can objectively measure scar color and volume and measure the effect of scar on motion of the face and…
- Trial name
- NCT00242970
- Testing
- 3-Dimensional Color Scanning
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Legacy Health System
Cicatrix
Fractional Microplasma Radiofrequency Technology for Non-hypertrophic Post-burn Scars in Asians: A Prospective Study of 95 Patients
A prospective study to evaluate the efficacy and safety of FMRT for treating non-hypertrophic post-burn scars in an Asian population.
- Trial name
- NCT02861248
- Testing
- Fractional micro-plasma radiofrequency treatment
- Where
- China
- Volunteers
- 95 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Stem Cell Media, Hypertrophic Scar
Regenerative Effects of Human Stem Cell Media After Laser Therapy in Hypertrophic Scar
The purpose of this study was to determine the effect of combined treatment using nonablative laser and human stem cell media (HSCM) on the regeneration of hypertrophic scars that occurred after burns.
- Conditions
- Stem Cell Media, Hypertrophic Scar, Regeneration
- Trial name
- NCT05004779
- Testing
- human stem cell conditioned media was applied after non-ablative laser therapy, normal saline was applied after non ablative laser therapy
- Volunteers
- 30 people
- Sponsor
- Hangang Sacred Heart Hospital
Hypertrophic Scarring After Burn Injury
Effectiveness of Pressure Garment Therapy After Burns
Purpose - To determine the effectiveness of custom-fit pressure garment therapy in the prevention of hypertrophic scarring in healed burns. Background - Approximately one million people are burned each year in the United States.
- Trial name
- NCT01005732
- Testing
- Custom fabricated pressure garments
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Washington
Hypertrophic Scar
Cost-Effectiveness of ESWT Plus Rehabilitation vs Rehabilitation Alone in Post-Burn Scars
This randomized controlled trial (RCT) will evaluate the cost-effectiveness of combining extracorporeal shock wave therapy (ESWT) with standard rehabilitation versus standard rehabilitation alone for the management of…
- Trial name
- NCT06913257
- Testing
- ESWT Combined with Standard Rehabilitation, Standard Rehabilitation Therapy Alone
- Where
- Egypt
- Volunteers
- 104 people
- Sponsor
- Al Hayah University In Cairo