Clinical trials: Population
Cardiac Surgical Procedures, Cardiac Surgical Procedures (Postoperative Population)
Vasoactive Inotropic Score in Adult Cardiac Surgery Outcomes
This study looked at whether a bedside score called the Vasoactive Inotropic Score (VIS) could help doctors predict which adult patients are at higher risk of complications after heart surgery that uses a heart-lung machine…
- Trial name
- NCT07745283
- Where
- India
- Volunteers
- 635 people
- Sponsor
- Sir Ganga Ram Hospital
Perinatal Population Health
Enhancing Perinatal Population Health Through Community Care Hubs
Enhancing Perinatal Population Health through Community Care Hubs (CARE) is designed to test system level, organizational level, and workforce level strategies that may activate individual, community health worker (CHW), CHW…
- Trial name
- CARE (NCT07869212)
- Testing
- Integrated Data Systems, Learning Collaborative, Resiliency Skill Building
- Volunteers
- 8 people
- Sponsor
- Ohio State University
Cardiac Surgical Procedures (Postoperative Population), Critical Illness
BIS in ICU Interventional Study
This study will test whether using a Bispectral Index (BIS) monitor to guide sedation can reduce the amount of sedative medication given to adults in the intensive care unit (ICU) after cardiac surgery.
- Conditions
- Cardiac Surgical Procedures (Postoperative Population), Critical Illness, Postoperative Complications (Cardiopulmonary), Delirium - Postoperative
- Trial name
- NCT07350122
- Testing
- Device-guided sedation, standard sedation practice
- Volunteers
- 144 people
- Sponsor
- Medical University of Graz
Healthy Population
A Study to Determine Safety, Pharmakokinetics and Efficacy of the Different Doses of VL-SE-01 in Healthy Participants.
The present study is a randomized, placebo-controlled, parallel study. 250 participants will be screened, and considering a screening failure rate of 20%, approximately 200 participants will be randomized in a ratio of 1:1:1:1:1…
- Trial name
- NCT06473246
- Testing
- CBD Isolate (25 mg/0.5 ml), CBD Isolate (40 mg/0.5 ml), CBD Isolate (50 mg/0.5 ml)
- Where
- 6 sites in India
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Age-Related (Dry) Macular Degeneration, Age-Related Macular Degeneration (AMD)
MIND-AMD Study: a Multidisciplinary Investigation of Neuroretinal Damage in Age-related Macular Degeneration.
Age-related macular degeneration (AMD) is the major cause of legal blindness in developed countries. Intermediate AMD represents the most frequent stage.
- Conditions
- Age-Related (Dry) Macular Degeneration, Age-Related Macular Degeneration (AMD), AMD Population - Intermediate or Advanced AMD, AMD and Macular Edema
- Trial name
- MIND-AMD (NCT07847151)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Aging, Veterans
Geri Pride: Feasibility Pilot of a Group Intervention for Older Veterans
There are over one million Veterans who identify as lesbian, gay, bisexual, (LGB) or a related identity. Older LGB Veterans face unique hurdles as they age, including stress, anxiety, heart disease, cancer, decreased ability to…
- Conditions
- Aging, Veterans, Social Determinants of Health, Health Disparate Minority and Vulnerable Populations
- Trial name
- NCT07831759
- Testing
- Geri Pride Health Promotion Group
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Mental Health Disorder, Family Navigation
Engaging Mental Health Services for Preschoolers at Risk
Most mental health (MH) disorders develop in early childhood but are not clinically identified or treated until later-delaying treatment services that could prevent the enduring effects of long-term MH problems.
- Conditions
- Mental Health Disorder, Family Navigation, Minoritized Population, Preschool Age Children
- Trial name
- NTRI-MH (NCT07054554)
- Testing
- NTRI-MH
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Healthy Adolescents in School-based Population, Emotional Neglect
Recognizing Emotional Neglect and Help-Seeking Intention Among Adolescents in Brussels
The goal of this study is to find out how well adolescents in Dutch-speaking secondary schools in Brussels can recognize emotional neglect, and how this relates to their intention to seek help. The main research questions are: 1.
- Conditions
- Healthy Adolescents in School-based Population, Emotional Neglect, Help-Seeking Behavior
- Trial name
- NCT07365891
- Testing
- Emotional neglect vignettes
- Where
- Belgium
- Volunteers
- 749 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Longitudinal Studies, Prospective Studies
Clinical Time and Temporal Dynamics Study (CLIN-TIME)
TH-CLINICAL-TIME is a prospective, longitudinal observational study evaluating how changes in clinical measurements over time may help researchers better understand patient health trajectories and clinically meaningful outcomes.
- Conditions
- Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests
- Trial name
- CLIN-TIME (NCT07812831)
- Testing
- No Study-Assigned Intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Urinary Incontinence (UI), Urinary Incontinence
URINARY INCONTINENCE AND GERIATRIC SYNDROMES
The aim of this cross-sectional observational study is to examine the independent associations of urinary incontinence severity and post-void residual urine volume with frailty and other geriatric outcomes in older adults…
- Conditions
- Urinary Incontinence (UI), Urinary Incontinence, Urinary Incontinence in Old Age, Urinary Incontinence in Geriatric Population
- Trial name
- NCT07813702
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- MERT UYSAL
Population Genomic Screening Implementation Best Practices
Facilitating the Implementation of Population-wide Genomic Screening
This is a multi-site hybrid implementation-effectiveness trial that uses a stepped-wedge cluster randomized design to evaluate the impact of the FOCUS toolkit, a multicomponent implementation guide, on improving the…
- Trial name
- FOCUS (NCT07806643)
- Testing
- FOCUS Toolkit Training
- Where
- 7 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Population Health Management, Patient Navigation
AI-Supported Care Engagement for Next-step Delivery - Medicare Advantage
ASCEND-MA is an embedded, health-services study of at-risk Medicare Advantage members attributed to Intermountain Health in Utah.
- Trial name
- ASCEND-MA (NCT07804095)
- Testing
- AI-Supported Rising-Risk Care Navigation
- Where
- United States
- Volunteers
- 9,906 people
- Sponsor
- Intermountain Health Care, Inc.
General Population, no Specific Condition
Heat Waves, Urban Heat Islands, and Wellbeing and Health: a Mobile Sensing Approach
The first objective of H3Sensing is to investigate outdoor environmental, building, dwelling, situational, and behavioral determinants of objectively assessed personal heat stress over daily movements during warm periods.
- Trial name
- H3Sensing (NCT06850025)
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Cancer Screening, Transgender
Cervical and Endometrial Cancer Screening in Patients Seeking Gender-Affirming Hysterectomy
This study aims to quantify the rates of cervical cancer screening and endometrial sampling prior to gender-affirming hysterectomy, assess the need for these tests in TGD individuals, and explore patient-centered options for…
- Conditions
- Cancer Screening, Transgender, Gender Diverse Populations
- Trial name
- NCT07075731
- Testing
- No intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Minnesota
Chronic Conditions, Multiple, Chronic Conditions
Evaluating Covered California's Grocery Support Program
This is a pragmatic randomized controlled trial (RCT) of Covered California's Grocery Support Program. This pragmatic RCT will test the efficacy of providing a monthly food card benefit for adults with food insecurity, a chronic…
- Conditions
- Chronic Conditions, Multiple, Chronic Conditions, Food Insecurity, Low-Income Population
- Trial name
- NCT07215897
- Testing
- Grocery Support Monthly Program, Grocery Support One-Time Payment
- Where
- United States
- Volunteers
- 6,975 people
- Sponsor
- University of California, San Francisco
Infectious Disease, Cardiovascular Diseases
Metabolic and Infectious Diseases in La Réunion (the REUNION Population-based Study)
The aim of the present study is to determine the prevalence of cardiometabolic and infectious disease in La Reunion (french oversea department and region of France).
- Conditions
- Infectious Disease, Cardiovascular Diseases, General Population, Metabolic Disease
- Trial name
- NCT05400824
- Testing
- Blood, DNA, feces, urine, hair and skin microbiota collection
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Impoverished Population, Older Adults (60 - 85 Years Old)
An mHealth-based Healthcare Professional-Lay Health Worker Partnership Program (mHLPP)
The project aimed at training female food delivery workers from Food Angel to perform basic health checks for older adults living alone in the community.
- Trial name
- NCT07691398
- Testing
- mHealth-Based Healthcare Professional-Lay Health Worker Partnership Program (mHLPP)
- Where
- Hong Kong
- Volunteers
- 230 people
- Sponsor
- The Hong Kong Polytechnic University
Brain Fog, Cognitive Impairment
Cognitive Task-Based Walking Effects on Cognition, Mood, Sleep, and Quality of Life in Older Adults With Brain Fog
This randomized controlled trial aims to investigate the effects of cognitive task-based walking exercise on cognitive function, depressive symptoms, sleep quality, and quality of life in older adults experiencing brain fog.
- Conditions
- Brain Fog, Cognitive Impairment, Geriatric Population
- Trial name
- NCT07396779
- Testing
- Cognitive Task-Based Walking Exercise, Walking-Only Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medipol University
COVID-19, Vulnerable Populations
The SINCERE Intervention to Address COVID-19 Health Disparities
The goal of this real world efficacy study is to understand the benefit of universal social needs screening, community-based service referrals, and telephonic follow-up as a scalable strategy for preventing COVID-19 transmission…
- Conditions
- COVID-19, Vulnerable Populations, Social Determinants of Health
- Trial name
- SINCERE (NCT05228886)
- Testing
- SINCERE, Scheduled Follow-Up, Standard of Care
- Where
- United States
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Andrea Wallace
Alzheimer Dementia (AD), Dementia
Clinical Risk Score Prediction for Risk of Dementia Among Late-life Population With Depression
The goal of this observational study is to learn about the ability of a point risk score prediction model, developed using electronic medical record data, to predict the risk of progression from geriatric depression to dementia…
- Conditions
- Alzheimer Dementia (AD), Dementia, Late Life Depression (LLD), Risk Scores
- Trial name
- NCT07676851
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University