Clinical trials: Physiological Responses
Healthy Participants
Physiological and Neurocognitive Responses to Multisensory Food Cues in VR
This study aims to investigate how food cravings change when visual food cues are enriched with sound, smell, and interactive experiences in a virtual reality (VR) environment.
- Trial name
- NCT07320209
- Testing
- Real food, Virtual Reality Food
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Marmara University
Autism Disorder
Triadic Interactions of Families With Autism and Oxytocin
The study will investigate the effects of an intranasal administration of oxytocin (OT) to parents of children with autism spectrum disorders (ASD) on the quality of mother-father-child interactions.
- Trial name
- TAO (NCT01912378)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Autonomous Nervous System, Fatigue
Exploring Physiological Responses of Virtual Reality Walking Exercise Versus Treadmill Walking in Healthy Individuals
This study aimed to systematically compare the physiological responses generated by walking exercises conducted in a VR environment versus those performed on a treadmill, with a specific focus on their impacts on the autonomic…
- Trial name
- NCT06679348
- Testing
- walking exercise on treadmill, Treadmill walking exercise using VR
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Atlas University
Erectile Dysfunction, Arterial Hypertension
Correlation Study of Vascular Parameters in Hypertensive Men With Erectile Dysfunction
The purpose of the study is to assess the correlation of FMD of brachial artery and carotid intima media thickness with ED severity and clinical response to vardenafil in hypertensive men.
- Conditions
- Erectile Dysfunction, Arterial Hypertension, Endothelial Dysfunction
- Trial name
- NCT01084187
- Testing
- Vardenafil
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario Pedro Ernesto
Physiological Response to Exercise, Perception of Exercise Difficulty
Perception of Physical Exertion in Healthy Weight and Obese Adolescents
Little is known regarding the relationship between perceived and physiological exertion in adolescents. The purpose of this study is to investigate the association between physiological and perceptual markers of effort during…
- Trial name
- NCT01695785
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Thermoregulation
Physiological Responses to Heat Stress During High-risk Events
Exertional heat stroke (EHS) affects ~500 Military Personnel and over 100 Soldiers every year, and it is believed that these numbers are underreported.
- Trial name
- NCT06907225
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Obesity
GLP-1 Response and Effect in Individuals With Obesity Causing Genetic Mutations
The obesity epidemic is attributable to dietary and behavioral trends acting on a person's genetic makeup to determine body mass and susceptibility to obesity-related diseases.
- Trial name
- NCT02082496
- Testing
- Liraglutide
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Septic Shock
The Effect of Rapid Fluid Challenge Under Pulmonary Artery Catheter Monitoring on Physiological Indexes of Patients With Septic Shock
Fluid challenge is often carried out in septic shock patients. Its responsiveness usually requires invasive monitoring. The pulmonary artery catheter(PAC) is the most effective means of monitoring.To use non-invasive methods is…
- Trial name
- NCT03661268
- Testing
- fluid chanllenge
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chengdu Fifth People's Hospital
Cardiovascular Fitness
Physiological and Perceptual Responses During 4-Second Exercise
The purpose of this study is to investigate the acute effects of different intensities (i.e., 50, 75, and 100% of maximal anaerobic power) of 4-s sprint interval exercise on physiological responses.
- Trial name
- NCT06912932
- Testing
- Preventive
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Healthy
Physiological Response to 5 Days Fasting
To investigate energy metabolism, anthropometry, blood pressure, gut microbiome, serum metabolome, glucose variability and neural mechanisms of food choice and mood before and after 5 days of fasting as well as their persistence…
- Trial name
- NCT04452916
- Testing
- Buchinger fasting
- Where
- Germany
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Heart Failure
Selective Coronary Vein Sampling in Left Bundle Branch Block and CRT
Cardiac resynchronisation therapy (CRT) prolongs the life and improves the symptoms in patients with heart failure and electrical dyssynchrony.
- Trial name
- MicroCRT (NCT02396875)
- Testing
- Blood sampling and exercise protocol pre and post CRT implant, Peripheral blood sampling, Central blood sampling pre and post CRT implant
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Mechanically Ventilated Patients
Effect Of Clustered Nursing Interventions On Physiological Response In Critically Ill Patients
To determine physiological responses related to clustered nursing interventions among critically ill patients.
- Trial name
- NCT04134481
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Systemic Inflammatory Response Syndrome
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery
The aim of the study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of inflammatory response related complications in patients undergoing heart surgery with use of cardiopulmonary…
- Trial name
- INFLACOR (NCT01020409)
- Testing
- cardiac surgery with CPB use
- Where
- Poland
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Healthy, Pre Hypertension
Race, Natriuretic Peptides and Physiological Perturbations
The purpose of the study is to understand the origins of differential response to beta-blockers in African-Americans and may provide insight regarding racial differences in cardiovascular risk.
- Trial name
- NCT03070184
- Testing
- Exercise capacity VO2 max determination, Standardized meals, Exercise challenge
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Exercise Performance
U-LABA/ICS Effects on Exercise Performance, Vilanterol
The purpose of the project is to investigate exercise performance in humans following bronchodilation induced by acute inhalation of beta2-agonist vilanterol + fluticasone furoate
- Trial name
- NCT06066606
- Testing
- Vilanterol and Fluticasone Furoate (low dose), Vilanterol and Fluticasone Furoate (high dose)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Gene Expression
Neural and Physiological Responses to Real-World Experiences
UCLA researchers looking for healthy individuals (aged 35-50) who have a home computer with internet access, are not pregnant, planning to become pregnant, or currently breastfeeding (if female), to participate in a study…
- Trial name
- NCT01723410
- Testing
- Writing about people, Writing about places, objects
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Erectile Dysfunction, Benign Prostatic Hyperplasia
Efficacy, Safety and Dose-response of Udenafil in Patients With Benign Prostatic Hyperplasia and Erectile Dysfunction
The purpose of this study is to evaluate the efficacy, dose-response and safety of udenafil 25 mg, 50 mg and 75 mg every day (q.d.) for 12 weeks in the treatment of lower urinary tract symptoms (LUTS) associated with benign…
- Trial name
- NCT01967251
- Testing
- Udenafil
- Where
- 8 sites in Mexico
- Sponsor
- Takeda
Heart Diseases
APPROPRIATE - Rate Adaptive Pacing Sensor
The APPROPRIATE study will compare differences in functional capacity (peak VO2) between chronotropically incompetent patients randomized to receive rate responsive pacing driven by either the minute ventilation…
- Trial name
- APPROPRIATE (NCT00757666)
- Testing
- Rate adaptive pacemaker
- Where
- 2 sites in United States
- Volunteers
- 566 people
- Sponsor
- Boston Scientific Corporation
Caffeine
The Repeatability of the Effect of Caffeine Supplementation on Submaximal Physiological Responses and Cycling Time Trial Performance
Recently, Grgic (2018) discussed the concept of responders and non-responders to caffeine supplementation highlighting the importance of the repeatability of results.
- Trial name
- NCT06935214
- Testing
- Caffeine
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Acute Physiological Effects of Organic Guayusa Extract
Acute Effects of Organic Guayusa Extract
Guayusa extract is a caffeinated tea leaf unique blend of antioxidants and caffeine. It is marketed as an ingredient that can help support energy and performance with potential health-related benefits.
- Trial name
- NCT05928195
- Testing
- Acute Moderate-Dose Guayusa Extract Supplementation, Acute High-Dose Guayusa Extract Supplementation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Nathaniel Jenkins