Cardiovascular FitnessNCT06912932
Physiological and Perceptual Responses During 4-Second Exercise
A study testing Preventive in people with Cardiovascular Fitness, run by University of Texas at Austin at 1 site in United States.
Trial summary
The purpose of this study is to investigate the acute effects of different intensities (i.e., 50, 75, and 100% of maximal anaerobic power) of 4-s sprint interval exercise on physiological responses. Read more about this study
- Who is it for?
- Ages 18 to 30 yearsHealthy volunteers can take part
- Conditions the study is for
- Cardiovascular Fitness
- What is being tested?
- Preventive
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 11 participants
- Where
- 1 siteUnited States
- Study dates
- 4 Apr 2023to 2 Oct 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Young (18-30),
- Healthy,
- Recreationally active, but untrained (not meeting ACSM's recommendations of 150 min/week of moderate-vigorous aerobic exercise)
Who cannot join
- Cardiovascular disease
- Smoking
- Subjects who were exercising regularly (>75 min/week) were excluded.
Trial locations and contacts
1 site in 1 country.
United States1 site
Human Performance Laboratory, Department of Kinesiology and Health Education, the University of Texas at Austin
Austin, Texas, 78712
About this study
Official title: The Effects of The Exercise Intensity and Rest Duration on Physiological and Perceptual Responses During 4-Second Sprint Interval Exercise
The purpose of this study is to investigate the acute effects of different intensities (i.e., 50, 75, and 100% of maximal anaerobic power) of 4-s sprint interval exercise on physiological responses. Secondly, it will determine the relationship between intensity and recovery duration (i.e., 15, 30, or 45-s) that will stimulate the cardiovascular and metabolic systems.
Read the detailed description
Background Short sprint interval training (sSIT) is typically performed at maximal intensity, generating power far above what is needed to reach peak oxygen consumption (VO₂peak). However, the physiological effects of submaximal sprint intensities and different recovery periods are not well understood.
Study Aim This study examined how power output and oxygen consumption (VO₂) respond to repeated 4-second sprints at 50%, 75%, and 100% of maximal power (Pmax) with rest periods of 15, 30, or 45 seconds.
Methods Eleven recreationally active participants completed nine trials, each consisting of thirty 4-second cycling sprints under different intensity and recovery conditions.
- Conditions
- Cardiovascular Fitness
- Being tested
- Preventive
- Keywords
- exercise, cardiovascular fitness, sprint, vo2max, interval training
- Medical subject headings
- Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
PreventiveBehavioural
systematically investigate the acute physiological responses induced by three levels of %Pmax intensities (50% and 75% of Pmax and all-out efforts) with three varying rest periods (15, 30, and 45-s) between thirty 4-s sprints.
| Study group | Role | What they receive |
|---|---|---|
| 50% Pmax and 15-s rest duration | Active comparator | Participants used 50% Pmax and 15-s rest duration during 30 bouts of 4-s sprint interval training. Receives: Behavioral: Preventive |
| 50% Pmax and 30-s rest duration | Active comparator | Participants used 50% Pmax and 30-s rest duration during 30 bouts of 4-s sprint interval training. Receives: Behavioral: Preventive |
| 50% Pmax and 45-s rest duration4 | Active comparator | Participants used 50% Pmax and 45-s rest duration during 30 bouts of 4-s sprint interval training. Receives: Behavioral: Preventive |
| 75% Pmax and 15-s rest duration | Active comparator | Participants used 75% Pmax and 15-s rest duration during 30 bouts of 4-s sprint interval training. Receives: Behavioral: Preventive |
| 75% Pmax and 30-s rest duration | Active comparator | Participants used 75% Pmax and 30-s rest duration during 30 bouts of 4-s sprint interval training. Receives: Behavioral: Preventive |
| 75% Pmax and 45-s rest duration | Active comparator | Participants used 75% Pmax and 45-s rest duration during 30 bouts of 4-s sprint interval training. Receives: Behavioral: Preventive |
| All-out Pmax and 15-s rest duration | Experimental | Participants used all-out Pmax and 15-s rest duration during 30 bouts of 4-s sprint interval training. Receives: Behavioral: Preventive |
| all-out Pmax and 30-s rest duration | Experimental | Participants used all-out Pmax and 30-s rest duration during 30 bouts of 4-s sprint interval training. Receives: Behavioral: Preventive |
| all-out Pmax and 45-s rest duration | Experimental | Participants used all-out Pmax and 45-s rest duration during 30 bouts of 4-s sprint interval training. Receives: Behavioral: Preventive |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cardiovascular changes
The %VO2peak associated with repeated submaximal power sprints (%Pmax), particularly when paired with varying rest periods, remains unknown. The aim of this study was to systematically investigate the cardiovascular changes for better exercise programming, measured in mL/min/kg.
Measured: From enrollment (Day 1) to the end of treatment (9 trials) (Day 11), through study completion, an average of 5 weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Apr 2025
- Study start4 Apr 2023
- Primary completion2 Oct 2024
- Study completion2 Oct 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cardiovascular FitnessStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 11 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Texas at Austin
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06912932
- Sponsor's protocol ID
- STUDY00004240-CR01
- Status last verified
- Mar 2025
- First submitted
- 24 Mar 2025
- Last updated
- 6 Apr 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of The Exercise Intensity and Rest Duration on Physiological and Perceptual Responses During 4-Second Sprint Interval Exercise
- ClinicalTrials.gov ID
- NCT06912932
- Acronym / sponsor ID
- STUDY00004240-CR01
- Conditions
- Cardiovascular Fitness
- Keywords
- exercise, cardiovascular fitness, sprint, vo2max, interval training
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 11 participants (actual)
- Lead sponsor
- University of Texas at AustinUniversity, hospital or other
- Study start
- 4 Apr 2023 (actual)
- Primary completion
- 2 Oct 2024 (actual)
- Study completion
- 2 Oct 2024 (actual)
- First posted
- 6 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to investigate the acute effects of different intensities (i.e., 50, 75, and 100% of maximal anaerobic power) of 4-s sprint interval exercise on physiological responses. Secondly, it will determine the relationship between intensity and recovery duration (i.e., 15, 30, or 45-s) that will stimulate the cardiovascular and metabolic systems.
Detailed description
Background Short sprint interval training (sSIT) is typically performed at maximal intensity, generating power far above what is needed to reach peak oxygen consumption (VO₂peak). However, the physiological effects of submaximal sprint intensities and different recovery periods are not well understood.
Study Aim This study examined how power output and oxygen consumption (VO₂) respond to repeated 4-second sprints at 50%, 75%, and 100% of maximal power (Pmax) with rest periods of 15, 30, or 45 seconds.
Methods Eleven recreationally active participants completed nine trials, each consisting of thirty 4-second cycling sprints under different intensity and recovery conditions.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 9
| Arm | Type | Receives |
|---|---|---|
| 50% Pmax and 15-s rest duration | Active comparator | Behavioral: PreventiveParticipants used 50% Pmax and 15-s rest duration during 30 bouts of 4-s sprint interval training. |
| 50% Pmax and 30-s rest duration | Active comparator | Behavioral: PreventiveParticipants used 50% Pmax and 30-s rest duration during 30 bouts of 4-s sprint interval training. |
| 50% Pmax and 45-s rest duration4 | Active comparator | Behavioral: PreventiveParticipants used 50% Pmax and 45-s rest duration during 30 bouts of 4-s sprint interval training. |
| 75% Pmax and 15-s rest duration | Active comparator | Behavioral: PreventiveParticipants used 75% Pmax and 15-s rest duration during 30 bouts of 4-s sprint interval training. |
| 75% Pmax and 30-s rest duration | Active comparator | Behavioral: PreventiveParticipants used 75% Pmax and 30-s rest duration during 30 bouts of 4-s sprint interval training. |
| 75% Pmax and 45-s rest duration | Active comparator | Behavioral: PreventiveParticipants used 75% Pmax and 45-s rest duration during 30 bouts of 4-s sprint interval training. |
| All-out Pmax and 15-s rest duration | Experimental | Behavioral: PreventiveParticipants used all-out Pmax and 15-s rest duration during 30 bouts of 4-s sprint interval training. |
| all-out Pmax and 30-s rest duration | Experimental | Behavioral: PreventiveParticipants used all-out Pmax and 30-s rest duration during 30 bouts of 4-s sprint interval training. |
| all-out Pmax and 45-s rest duration | Experimental | Behavioral: PreventiveParticipants used all-out Pmax and 45-s rest duration during 30 bouts of 4-s sprint interval training. |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Young (18-30),
- Healthy,
- Recreationally active, but untrained (not meeting ACSM's recommendations of 150 min/week of moderate-vigorous aerobic exercise)
Key exclusion criteria (3 listed)
- Cardiovascular disease
- Smoking
- Subjects who were exercising regularly (>75 min/week) were excluded.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Preventivesystematically investigate the acute physiological responses induced by three levels of %Pmax intensities (50% and 75% of Pmax and all-out efforts) with three varying rest periods (15, 30, and 45-s) between thirty 4-s sprints. | Behavioural | 50% Pmax and 15-s rest duration, 50% Pmax and 30-s rest duration, 50% Pmax and 45-s rest duration4, 75% Pmax and 15-s rest duration, 75% Pmax and 30-s rest duration, 75% Pmax and 45-s rest duration, All-out Pmax and 15-s rest duration, all-out Pmax and 30-s rest duration, all-out Pmax and 45-s rest duration |
Primary outcome
Cardiovascular changes
Time frame: From enrollment (Day 1) to the end of treatment (9 trials) (Day 11), through study completion, an average of 5 weeks.
The %VO2peak associated with repeated submaximal power sprints (%Pmax), particularly when paired with varying rest periods, remains unknown. The aim of this study was to systematically investigate the cardiovascular changes for better exercise programming, measured in mL/min/kg.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Apr 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Preventive in people with Cardiovascular Fitness, run by University of Texas at Austin at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cardiovascular changes (time frame: From enrollment (Day 1) to the end of treatment (9 trials) (Day 11), through study completion, an average of 5 weeks.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Apr 2025.