Clinical trials: Osseointegration
Amputation; Traumatic, Leg, Lower
Transtibial Osseointegration
Purpose: Aim 1: Quantify soft tissue complications and infections of service members with transtibial amputations treated with OPRA OI and compare them to transfemoral OI service members.
- Trial name
- TOSS (NCT06636136)
- Testing
- OPRA
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Walter Reed National Military Medical Center
Tooth Loss, Tooth Diseases
The Cortical Shield for Facial Bone Reconstruction
To evaluate a novel technique of bone regeneration and simultaneous implant placement in severely damaged sockets.
- Conditions
- Tooth Loss, Tooth Diseases, Tooth Fracture, Tooth Injuries
- Trial name
- NCT04827693
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Implant Stability and Osseointegration
Topical Dexamethasone, Ascorbic Acid, and BGP for Enhancing Implant Osseointegration
The goal of this clinical trial was to evaluate whether the topical application of a combination of dexamethasone, ascorbic acid, and β-sodium glycerophosphate could enhance implant osseointegration in adult dental implant…
- Trial name
- DAG (NCT07060859)
- Testing
- Topical Application of Dexamethasone, Ascorbic Acid, and β-Sodium Glycerophosphate
- Where
- Palestinian Territories
- Volunteers
- 18 people
- Sponsor
- Manar Ziad Foura-Matar
Dental Implants, Hyaluronic Acid
Assessment of Rapid Osseointegration of Dental Implants with Different Coatings
The study will assess early osseointegration of dental implant with three different coating materials through secondary implant stability
- Trial name
- NCT06650280
- Testing
- Hyaluronic Acid (HA), nano-hydroxyapatite, sandblasted acid etched
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Alveolar Bone Loss, Dental Implant
Magnetic Mallet Vs Conventional Drilling in D4 Posterior Maxilla
The goal of this clinical trial is to evaluate whether the magnetic mallet technique improves primary implant stability and clinical outcomes compared with conventional drilling during dental implant placement in the posterior…
- Conditions
- Alveolar Bone Loss, Dental Implant, Osseodensification Drilling Technique
- Trial name
- NCT07424820
- Testing
- Conventional drilling osteotomy, Magnetic mallet osteotomy
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Mosul
Implant Site Reaction
Assessment of Osseointegration Properties of Nano-Hydroxy Apatite Coated Titanium Implant
the purpose of this trial is to evaluate the osseointegration properties of nano-hydroxy apatite coated titanium implants in posterior maxilla.
- Trial name
- NCT05936775
- Testing
- nano-hydroxy apatite coated titanium implants, sandblasted large acid itched coated titanium implant
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Alveolar Bone Loss
Effect of Topical Melatonin Application on Dental Implant Osseointegration and Marginal Bone Level
Background: Melatonin (N-acetyl-5-methoxy-tryptamine) is an indoleamine synthesized and secreted by the pineal gland and other organs, such as the retina, bone marrow, and intestines in a circadian pattern.
- Trial name
- NCT04229719
- Testing
- N-acetyl-5-methoxytryptamine
- Where
- Iraq
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Implantation, Dental Implants
The Application of Root Analogy Implant in Immediate Implantation
The current clinical implant techniques used include immediate implantation, early implantation, and delayed implantation. With the acceleration of the current pace of life, immediate implantation is increasingly favored by…
- Conditions
- Dental Implantation, Dental Implants, Osseointegration
- Trial name
- RAI (NCT06449391)
- Testing
- RAI
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Tooth Loss, Partial Edentulism in the Maxilla or in the Mandible
Evaluation of Autogenous Bone Graft on Immediate Dental Implant Osseointegration Using Piezosurgery
This clinical study aims to evaluate the clinical and radiographic outcomes of immediate dental implant placement in mandibular premolar sites.
- Trial name
- ABG-IDIP (NCT07705399)
- Testing
- Immediate implant with autogenous bone graft, Immediate implant without bone graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Hearing Loss - Conductive
Stability of the Cochlear Baha BI300/BA400 Implant System Loaded From 1 Week Post-surgery
Objectives To evaluate the safety of processor loading of the Cochlear BI300/BA400 implant system 1 week after implantation To evaluate the short term soft tissue healing and the long term skin reaction, with the new Cochlear…
- Trial name
- NCT02096809
- Testing
- One week loading of Bone Anchored Hearing Aid (BAHA), Cochlear Baha BI300/BA400 Implant System
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Aarhus University Hospital
Bone Density, Low
Comparing the Hydrodynamic Piezoelectric Technique With Osseodensification for the Assessment of Internal Sinus Iift-ing
Successful osseointegration considered the cornerstone in implant stability which predict the highest implants success outcomes.
- Trial name
- RCT (NCT06285903)
- Testing
- internal sinus lift surgery
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Tooth Extraction, Dental Implants
Platelet Rich Fibrin and Concentrated Growth Factors on Osseointegration of Immediate Implants
This study will involve 14 patients with mandibular premolars indicated for extraction and immediate replacement. The patients will be randomly allocated into two groups and each patient will receive one implant.
- Trial name
- NCT05101954
- Testing
- Concentrated Growth Factors (CGF), Platelet-Rich Fibrin (PRF)
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Hams Hamed Abdelrahman
Dental Implant
Investigating Implant Surface Effect on Osseointegration: NGA vs. ModSLA
This study aims to characterise the stability of crestal bone levels one year after loading, the associated aesthetic outcomes, immunological response, prosthodontic outcomes as well as overall patient reported outcome measures…
- Trial name
- NCT06086873
- Testing
- Implant Type
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization
Graftless TSFE Via Self-tapping Implants
This prospective clinical trial aims to evaluate the efficiency, safety, and reliability of a minimally invasive graftless transcrestal sinus lifting approach with simultaneous dental implant placement in patients with edentulous…
- Conditions
- Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization, Alveolar Bone Atrophy
- Trial name
- G-TSFE (NCT07424742)
- Testing
- Graftless Transcrestal Sinus Membrane Elevation with Simultaneous Implant Placement
- Where
- Yemen
- Volunteers
- 20 people
- Sponsor
- Sana'a University
Lower Extremity Amputation
Instrumental Analysis of Walking in People With Osseointegrated Prostheses for Lower Extremity Amputation: Comparative Evaluation With Traditional Socket Prostheses
The currently accepted standard for rehabilitation and mobility following amputation is a socket-mounted prosthesis. Osseointegration is an alternative method that has gradually gained greater acceptance in the last 30 years.
- Trial name
- AStrO-OI (NCT04934839)
- Testing
- Test of standing balance (Equitest System). Test of walking in tied and split conditions on a force-sensorized split-belt treadmill.
- Where
- 2 sites in Italy
- Volunteers
- 8 people
- Sponsor
- Istituto Auxologico Italiano
Dental Implants, Humans
Atraumatic Zirconia Abutment Versus Customized Composite Healing Abutment in Maxilla or Mandible.
40 patients are included in the study, 20 patients in group 1 (=closure with composite material shaper; test group) and 20 patients in group 2 (=closure with custom-made zirconia oxide abutment; control group).
- Conditions
- Dental Implants, Humans, Dental Implants, Single-Tooth, Male
- Trial name
- NCT05748379
- Testing
- Kompozite closure, Individual abutment
- Where
- Latvia
- Volunteers
- 44 people
- Sponsor
- SIA Adenta
Dental Implant Placement, Ozone Therapy
Ozone Versus Conventional Socket Disinfection for Primary Dental Implant Stability
This randomized split-mouth controlled clinical trial aims to compare the effects of ozone and conventional implant site disinfection on primary and early secondary implant stability.
- Trial name
- NCT07687680
- Testing
- Ozone Implant Site Disinfection, Conventional Socket Disinfection
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Zeliha Başak Çakır Erdil
Dental Implant Failed, Jaw, Edentulous, Partially
Osseodensification Versus Conventional Drilling for Implant Site Preparation
A total of 34 participants, who require replacement of an anterior or posterior single tooth with dental implant, will be randomly allocated to two equal sized groups.
- Conditions
- Dental Implant Failed, Jaw, Edentulous, Partially, Edentulous Alveolar Ridge, Osseointegration Failure of Dental Implant
- Trial name
- NCT06034067
- Testing
- Osseodensification osteotomy preparation, Standardized osteotomy preparation
- Where
- United Arab Emirates
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Implant Stability Quotient, Healing Abutment
Cover Screw vs Healing Abutment on Osseointegration
This randomized split-mouth clinical trial aims to compare the effects of using a cover screw versus a healing abutment on early implant stability and osseointegration.
- Conditions
- Implant Stability Quotient, Healing Abutment, Cover Screw
- Trial name
- NCT07687615
- Testing
- Healing Abutment, Cover Screw
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Zeliha Başak Çakır Erdil
Dental Implants, Osseointegration
Movement of Dental Implants During Osseointegration
Prospective multicenter observational study assessing whether dental implants undergo three-dimensional positional change between placement (T0) and pre-loading after osseointegration (T1).
- Trial name
- MOVs-OI (NCT07297147)
- Where
- 3 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Aula Dental Avanzada