Clinical trials: One-Lung Ventilation
One-lung Ventilation (OLV), Video-assisted Thoracis Surgery (VATS)
Comparison of Different Ventilation Modes in Video-Assisted Thoracoscopic Lung Resection
One-lung ventilation (OLV) is required for video-assisted thoracoscopic surgery (VATS) lung resection, but it exposes the dependent lung to atelectasis, high driving pressures, and oxidative stress, and is associated with…
- Trial name
- OLV-VENT (NCT07866170)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Lung Collapse, One-lung Ventilation
Brief Bronchial Suction for Lung Collapse During Uniportal VATS
The goal of this clinical trial is to learn whether a brief suction of the airway going to the surgical lung (bronchus) can help the lung collapse faster and more completely during uniportal video-assisted thoracoscopic surgery…
- Conditions
- Lung Collapse, One-lung Ventilation, Thoracic Anesthesia, Thoracic Surgery, Video-assisted
- Trial name
- NCT07660588
- Testing
- bronchial suction
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery
Video-guided Versus Conventional Right-sided Double-lumen Tube Placement for Thoracoscopic Surgery
Right-sided double-lumen tubes are used for lung isolation during thoracoscopic surgery but can be difficult to position because of right bronchial anatomy.
- Conditions
- Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery, One-lung Ventilation, Lung Cancer
- Trial name
- NCT07849400
- Testing
- Continuous video-guided right-sided double-lumen tube, Conventional right-sided double-lumen tube
- Where
- 3 sites in China
- Volunteers
- 566 people
- Sponsor
- Diansan Su
Thoracoscopic Surgery, Double Lumen Tube Intubation
Video-guided Versus Conventional Right-sided Double-Lumen Tubes for One-Lung Ventilation in Thoracoscopic Surgery
This multicentre randomised controlled trial compares a video-guided right-sided double-lumen tube with a conventional right-sided double-lumen tube in adults undergoing elective thoracoscopic surgery requiring one-lung…
- Conditions
- Thoracoscopic Surgery, Double Lumen Tube Intubation, One-Lung Ventilation
- Trial name
- RIGHT-VDLT (NCT07362797)
- Testing
- Video-guided right-sided double-lumen tube, Conventional right-sided double-lumen tube
- Where
- 3 sites in China
- Volunteers
- 566 people
- Sponsor
- Diansan Su
Thoracic Surgery, One-lung Ventilation
CT-Guided vs Conventional DLT Sizing in Thoracic Surgery
This is a prospective, randomized, single-blinded controlled trial designed to compare CT-guided versus conventional methods for selecting double-lumen tube (DLT) size in patients undergoing thoracic surgery requiring one-lung…
- Trial name
- CTDLT-SIZE (NCT07575763)
- Testing
- CT-Guided Group (Intervention), Conventional Group (Control)
- Where
- Jordan
- Volunteers
- 100 people
- Sponsor
- King Hussein Cancer Center
Women, Asian
Effect of Small Double-lumen Tube on the Intubation Time of Thoracoscopic Pulmonectomy in Asian Women
The purpose of this experiment is to verify whether selecting a double-lumen tube one size smaller based on the traditional personalized method can shorten the intubation time without increasing ventilation complications when…
- Conditions
- Women, Asian, Thoracic Surgery With One-lung Ventilation
- Trial name
- NCT07097584
- Testing
- Selecting the size of a Left Double-lumen endobronchialtube one size smaller than the traditional method, Selecting the size of a Left Double-lumen endobronchialtube according to traditional methods
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Zhejiang Cancer Hospital
Thoracic Surgery With One-lung Ventilation
ORI-Guided Oxygen Therapy During One-Lung Ventilation
High inspired oxygen concentrations (FiO₂) are commonly administered during general anesthesia to prevent hypoxemia. However, excessive oxygen administration may result in hyperoxemia, which has been associated with impaired…
- Trial name
- ORI-OLV (NCT07720778)
- Testing
- ORI-Guided FiO2 Titration, Conventional SpO₂-Guided FiO₂ Titration
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Konkuk University Medical Center
Lung Neoplasm, Lung Cancer
Lung Ultrasound to Assess Aeration Loss After Lung Resection Surgery
The purpose of this prospective observational study is to assess perioperative changes in lung aeration after lung resection surgery using lung ultrasound, and to explore their relationship with oxygenation, inflammatory…
- Conditions
- Lung Neoplasm, Lung Cancer, Lung Resection Surgery, Thoracic Surgery
- Trial name
- THORUS (NCT04677309)
- Testing
- Perioperative lung ultrasound assessment
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Ana Broseta Lleó
Thoracic Surgery With One-lung Ventilation, Lung Isolation
Efficacy and Safety of the Visual Bronchial Blocker for Lung Isolation Surgery
This multicenter, prospective, randomized, controlled clinical trial is initiated by the First Affiliated Hospital of Zhejiang University School of Medicine, with participation from Peking Union Medical College Hospital, the…
- Conditions
- Thoracic Surgery With One-lung Ventilation, Lung Isolation, Bronchial Blockage, Anesthesia
- Trial name
- NCT07644104
- Testing
- Visual Bronchial Blocker, Conventional Bronchial Blocker
- Where
- China
- Volunteers
- 652 people
- Sponsor
- Zhejiang University
Thoracic Surgery, Videoassisted Thoracoscopic Surgery,One-lung Ventilation
The Impact of Video-assisted Thoracic Surgery and Regional Anaesthesia on Postoperative Opioid Consumption and Pain Scores
This present study aims is to compare the effects of ultrasound-guided paravertebral block, intertransverse process block, and erector spinae plane block on postoperative opioid consumption, and pain scores in patients undergoing…
- Conditions
- Thoracic Surgery, Videoassisted Thoracoscopic Surgery,One-lung Ventilation, Regional Anaesthesia, Postoperative Analgesia
- Trial name
- NCT07578545
- Testing
- Paravertebral block group, İntertransverse process block group, Erector spinae plane block group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Antalya Training and Research Hospital
Thoracic Surgery With One-lung Ventilation
Ultrasound vs. Auscultation and Fiberoptic Bronchoscopy for Double-Lumen Tube Placement
One-lung ventilation is frequently required in thoracic surgery and is most commonly achieved using double-lumen endobronchial tubes (DLTs).
- Trial name
- NCT07465510
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir City Hospital
Heart Valvular Disease, Coronary Arteriosclerosis
Comparison of Airway Management With Bronchial Blocker and Double-Lumen Tube in Single-Lung Ventilation
In this study, the primary aim is to compare the impact of using a double-lumen tube and bronchial blocker for single-lung ventilation in patients undergoing minimal invasive cardiac surgeries on postoperative pulmonary…
- Conditions
- Heart Valvular Disease, Coronary Arteriosclerosis, One-lung Ventilation
- Trial name
- NCT06299735
- Testing
- Minimally Invasive Cardiac Surgery (airway management with double-lumen tube), Minimally Invasive Cardiac Surgery (airway management with endobronchial blocker)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Surgery, One-lung Ventilation
Esophageal Pressure Measurements During One-lung Ventilation
The investigators will assess the feasibility and validity of esophageal pressure measurements during one-lung ventilation in the lateral position for surgery by comparing to lung collapse estimated from electrical impedance…
- Trial name
- NCT04725318
- Testing
- One-lung ventilation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Beth Israel Deaconess Medical Center
One-Lung Ventilation, Thoracic Surgery
Left Double Lumen Tube Selection
The aim of this study was to determine the accuracy and practicality of ultrasound in the selection of double lumen tube and whether the complications that may occur intraoperatively and postoperatively can be reduced.
- Trial name
- NCT06457763
- Testing
- Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Marmara University
One-lung Ventilation (OLV), Thoracic Surgery
Comparison of FCV and VCV in One-Lung Ventilation
One-lung ventilation (OLV) is commonly used during thoracic surgery but may negatively affect lung mechanics and gas exchange. Different ventilation strategies are used during OLV, and their effects on respiratory parameters…
- Conditions
- One-lung Ventilation (OLV), Thoracic Surgery, Respiratory Mechanics
- Trial name
- FCVOLVent (NCT07392086)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Postoperative Pulmonary Complications (PPCs), One-lung Ventilation (OLV)
Individualized Open Lung Ventilation and Postoperative Pulmonary Complications in Thoracic Surgery
This prospective, single-center, randomized controlled trial aims to evaluate the efficacy of an intraoperative "Individualized Open Lung Ventilation" strategy compared to a standard lung-protective ventilation strategy in…
- Conditions
- Postoperative Pulmonary Complications (PPCs), One-lung Ventilation (OLV), Thoracic Surgery, Video Assisted
- Trial name
- NCT07387822
- Testing
- Standard Lung-Protective Ventilation, Individualized Open Lung Ventilation
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Aerospace Center Hospital
One-lung Ventilation (OLV)
Correlation of Oxygenation and Saturation Indices in One-Lung Ventilation
One-lung ventilation is commonly used during thoracic surgery but is frequently associated with impaired oxygenation and altered respiratory mechanics.
- Trial name
- OLV-INDICES (NCT07381517)
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
One Lung Ventilation in Thoracic Surgery
Oxygen Reserve Index Guided FiO₂ Titration in One-Lung Ventilation
One-lung ventilation (OLV) is routinely used during thoracic surgery to facilitate surgical exposure but is associated with an increased risk of intraoperative hypoxemia.
- Trial name
- NCT07359833
- Testing
- Oxygen Reserve Index (ORi)-guided oxygen titration
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gazi University
One-lung Ventilation
Nomogram for Prediction of Alveolo-arterial Gradient During One-lung Ventilation
The cause of hypoxia during one-lung ventilation is a common anaesthetic problem seen during thoracic surgery and is associated with increased fraction of shunted blood.
- Trial name
- NCT06376123
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
One Lung Ventilation in Thoracic Surgery
Comparison of Double-lumen Tube Intubation Between Fiberoptic Bronchoscopy and Video Laryngoscope
The goal of this clinical trial is to compare the first-attempt success rate in double-lumen tube intubation. The main question it aims to answer: Is there any difference in the first-attempt success rate of intubation between…
- Trial name
- NCT07241208
- Testing
- Fibertoptic Bronchoscopy
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Kyung Hee University Hospital at Gangdong