Thoracic SurgeryCTDLT-SIZENCT07575763
CT-Guided vs Conventional DLT Sizing in Thoracic Surgery
A study testing CT-Guided Group (Intervention) in people with Thoracic Surgery and One-lung Ventilation, run by King Hussein Cancer Center at 1 site in Jordan.
Trial summary
This is a prospective, randomized, single-blinded controlled trial designed to compare CT-guided versus conventional methods for selecting double-lumen tube (DLT) size in patients undergoing thoracic surgery requiring one-lung ventilation Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Thoracic Surgery, One-lung Ventilation
- What is being tested?
- CT-Guided Group (Intervention)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 siteJordan
- Study dates
- 15 May 2026to 1 Aug 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adult patients (≥18 years) scheduled for elective thoracic surgery requiring one-lung ventilation.
- Availability of preoperative thoracic CT imaging.
- Procedures requiring placement of a left-sided DLT.
- Patient who has a normal pulmonary function test.
Who cannot join
- Previous tracheal surgery
- Patient with difficult airway whom need bronchial blocker.
- Emergency thoracic procedures.
- Incomplete intraoperative or imaging data.
- Patient with severe obstruction or restriction.
- Pediatric patient
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Jordan1 site, 1 recruiting
- Recruiting
King Hussein Cancer Center
Amman, 11941
Moh'D Yousef, MD, +962796420055, MY.16674@KHCC.JO
Ahmad Al Kharabsheh, Fellow physician, 00962-796420055, AA.15386@KHCC.JO
About this study
Official title: CT-Guided Versus Traditional Selection of Double-Lumen Tube Size for One-Lung Ventilation in Thoracic Surgery: A Prospective Study
This is a prospective, randomized, single-blinded controlled trial designed to compare CT-guided versus conventional methods for selecting double-lumen tube (DLT) size in patients undergoing thoracic surgery requiring one-lung ventilation
Read the detailed description
This is a prospective, randomized, single-blinded controlled trial designed to compare CT-guided versus conventional methods for selecting double-lumen tube (DLT) size in patients undergoing thoracic surgery requiring one-lung ventilation. The study aims to evaluate whether preoperative computed tomography (CT)-based bronchial diameter measurement improves the accuracy of initial DLT size selection compared with conventional selection based on demographic parameters.
Eligible patients will be randomly assigned in a 1:1 ratio to either the CT-guided group or the conventional group.
- Conditions
- Thoracic Surgery, One-lung Ventilation
- Being tested
- CT-Guided Group (Intervention), Conventional Group (Control)
- Keywords
- Double-lumen tube, Thoracic anesthesia, CT-guided intubation, One-lung ventilation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
CT-Guided Group (Intervention)Other
Participants will undergo preoperative CT measurement of the bronchial diameter 10 mm distal to the carina. DLT size will be selected using manufacturer-recommended correlation charts based on CT measurements.
Conventional Group (Control)Other
DLT size will be selected using standard clinical criteria based on patient demographics, including sex, height, and weight, according to institutional standard tables.
| Study group | Role | What they receive |
|---|---|---|
| CT-Guided Group | Experimental | Participants will undergo preoperative CT measurement of the bronchial diameter 10 mm distal to the carina. DLT size will be selected using manufacturer-recommended correlation charts based on CT measurements. Receives: Other: CT-Guided Group (Intervention) |
| Conventional Group | Active comparator | DLT size will be selected using standard clinical criteria based on patient demographics, according to institutional standard tables. Receives: Other: Conventional Group (Control) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Successful selection of the correct DLT size on the first attempt (defined as optimal position and lung isolation without the need for tube exchange) using fiberoptic scope
the correct placement of a double-lumen tube (DLT) on the first attempt, achieving optimal tracheobronchial position and effective lung isolation as confirmed by fiberoptic bronchoscopy, without the need for tube exchange or repositioning.
Measured: During the intraoperative period (at first attempt of double-lumen tube placement)
Secondary outcomes (5)
Incidence of DLT replacement
Number of participants requiring replacement of the double-lumen tube (DLT) after initial placement due to incorrect size, malposition, or inadequate lung isolation
Measured: Intraoperative period (from initial DLT placement until end of surgery)
Time required for successful intubation
Time (in seconds) from insertion of the double-lumen tube into the mouth until successful tracheal placement and confirmation of correct positioning and lung isolation
Measured: Intraoperative period (from DLT insertion to confirmed successful placement)
Frequency of intraoperative hypoxia and peak airway pressure fluctuations
Incidence of episodes of intraoperative hypoxia and measurement of peak airway pressure fluctuations during one-lung ventilation.
Measured: Intraoperative period (from DLT insertion to confirmed successful placement)
Blinded assessment of surgeon satisfaction (lung isolation quality)
Surgeon satisfaction with lung isolation quality assessed using a standardized scoring scale, evaluated in a blinded manner at the end of the surgical procedure.
Measured: At the end of surgery (intraoperative assessment)
Post-operative sore throat or airway trauma
Incidence and severity of post-operative sore throat and/or signs of airway trauma (e.g., hoarseness, blood on suctioning, or mucosal injury if assessed) within 24 hours after extubation.
Measured: 24 hours post-extubation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 May 2026
- Study start15 May 2026
- Primary completion2 May 2028 (estimated)
- Study completion1 Aug 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Thoracic SurgeryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- King Hussein Cancer Center
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Moh'D Yousef, Consultant, Anesthesiology, Principal investigator, King Hussein Cancer Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07575763
- Sponsor's protocol ID
- 26 KHCC 59
- Acronym
- CTDLT-SIZE
- Status last verified
- Aug 2026
- First submitted
- 4 May 2026
- Last updated
- 7 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 7 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- CT-Guided Versus Traditional Selection of Double-Lumen Tube Size for One-Lung Ventilation in Thoracic Surgery: A Prospective Study
- ClinicalTrials.gov ID
- NCT07575763
- Acronym / sponsor ID
- CTDLT-SIZE / 26 KHCC 59
- Conditions
- Thoracic Surgery, One-lung Ventilation
- Keywords
- Double-lumen tube, Thoracic anesthesia, CT-guided intubation, One-lung ventilation
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- King Hussein Cancer CenterUniversity, hospital or other
- Study start
- 15 May 2026 (actual)
- Primary completion
- 2 May 2028 (estimated)
- Study completion
- 1 Aug 2028 (estimated)
- First posted
- 8 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a prospective, randomized, single-blinded controlled trial designed to compare CT-guided versus conventional methods for selecting double-lumen tube (DLT) size in patients undergoing thoracic surgery requiring one-lung ventilation
Detailed description
This is a prospective, randomized, single-blinded controlled trial designed to compare CT-guided versus conventional methods for selecting double-lumen tube (DLT) size in patients undergoing thoracic surgery requiring one-lung ventilation. The study aims to evaluate whether preoperative computed tomography (CT)-based bronchial diameter measurement improves the accuracy of initial DLT size selection compared with conventional selection based on demographic parameters.
Eligible patients will be randomly assigned in a 1:1 ratio to either the CT-guided group or the conventional group.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| CT-Guided Group | Experimental | Other: CT-Guided Group (Intervention)Participants will undergo preoperative CT measurement of the bronchial diameter 10 mm distal to the carina. DLT size will be selected using manufacturer-recommended correlation charts based on CT measurements. |
| Conventional Group | Active comparator | Other: Conventional Group (Control)DLT size will be selected using standard clinical criteria based on patient demographics, according to institutional standard tables. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Adult patients (≥18 years) scheduled for elective thoracic surgery requiring one-lung ventilation.
- Availability of preoperative thoracic CT imaging.
- Procedures requiring placement of a left-sided DLT.
- Patient who has a normal pulmonary function test.
Key exclusion criteria (6 listed)
- Previous tracheal surgery
- Patient with difficult airway whom need bronchial blocker.
- Emergency thoracic procedures.
- Incomplete intraoperative or imaging data.
- Patient with severe obstruction or restriction.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| CT-Guided Group (Intervention)Participants will undergo preoperative CT measurement of the bronchial diameter 10 mm distal to the carina. DLT size will be selected using manufacturer-recommended correlation charts based on CT measurements. | Other | CT-Guided Group |
| Conventional Group (Control)DLT size will be selected using standard clinical criteria based on patient demographics, including sex, height, and weight, according to institutional standard tables. | Other | Conventional Group |
Primary outcome
Successful selection of the correct DLT size on the first attempt (defined as optimal position and lung isolation without the need for tube exchange) using fiberoptic scope
Time frame: During the intraoperative period (at first attempt of double-lumen tube placement)
the correct placement of a double-lumen tube (DLT) on the first attempt, achieving optimal tracheobronchial position and effective lung isolation as confirmed by fiberoptic bronchoscopy, without the need for tube exchange or repositioning.
5 secondary outcomes
Incidence of DLT replacement
Time frame: Intraoperative period (from initial DLT placement until end of surgery)
Time required for successful intubation
Time frame: Intraoperative period (from DLT insertion to confirmed successful placement)
Frequency of intraoperative hypoxia and peak airway pressure fluctuations
Time frame: Intraoperative period (from DLT insertion to confirmed successful placement)
Blinded assessment of surgeon satisfaction (lung isolation quality)
Time frame: At the end of surgery (intraoperative assessment)
Post-operative sore throat or airway trauma
Time frame: 24 hours post-extubation
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Aug 2026.
- Individual participant dataSharing planned: Undecided
Related trials for Thoracic Surgery
RecruitingObservational study
Label-free Femtosecond Laser Imaging Combined With the Fast Lung Artificial Intelligence Model for Rapid Intraoperative Diagnosis of Lung Surgical Specimens: A Multicentre, Prospective, Parallel-workflow, Non-inferiority Study.
Lung Cancer
Not yet recruiting
The Effect of Compound Chamomile and Lidocaine Hydronchloride Gel as an Endotracheal Tube Lubricant on Postoperative Pharyngeal and Laryngeal Complications in Thoracic Surgery Patients
Postoperative Sore Throat
RecruitingPhase 3
Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial
Lung Non-Small Cell Carcinoma
Active, not recruiting
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)
Stage IB Lung Non-Small Cell Carcinoma AJCC v7, Stage II Lung Non-Small Cell Cancer AJCC v7
RecruitingPhase 2/3
Gabapentin to Reduce Opioid Use Postoperatively (GROUP) in Children
Pain, Postoperative
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Moh'D Yousef, Consultant, Anesthesiology principal investigator
King Hussein Cancer Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing CT-Guided Group (Intervention) in people with Thoracic Surgery and One-lung Ventilation, run by King Hussein Cancer Center at 1 site in Jordan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 7 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Jordan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Moh'D Yousef, Consultant (+962796420055, MY.16674@KHCC.JO), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Successful selection of the correct DLT size on the first attempt (defined as optimal position and lung isolation without the need for tube exchange) using fiberoptic scope (time frame: During the intraoperative period (at first attempt of double-lumen tube placement)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Aug 2026.