Thoracic SurgeryNCT07578545
The Impact of Video-assisted Thoracic Surgery and Regional Anaesthesia on Postoperative Opioid Consumption and Pain Scores
An observational study of Thoracic Surgery and Videoassisted Thoracoscopic Surgery,One-lung Ventilation, run by Antalya Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
This present study aims is to compare the effects of ultrasound-guided paravertebral block, intertransverse process block, and erector spinae plane block on postoperative opioid consumption, and pain scores in patients undergoing VATS. Read more about this study
- Who is it for?
- Ages 18 to 75 years
- Conditions the study is for
- Thoracic Surgery, Videoassisted Thoracoscopic Surgery,One-lung Ventilation, Regional Anaesthesia
- What is being tested?
- Paravertebral block group, İntertransverse process block group and Erector spinae plane block group
- How many people
- 96 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 4 May 2026to 4 Nov 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: It is planned to include ASA score I-III adult patients who are planned to undergo elective VATS
Who may be able to join
- aged 18-75 years
- American Society of Anaesthesiology (ASA) score I-III
- body mass index (BMI) <35kg/m2
- scheduled for elective VATS
Who cannot join
- ASA score ≥4
- BMI ≥35 kg/m2
- declining to give written informed consent
- controendications for block application
- inability to undergo block application
- history neurological disease or peripheral nerve disease
Show all 9Show fewer
- history of chronic opioid use
- history of severe liver or kidney failure
- patients admitted to the intensive care unit postoperatively intubated
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Batuhan Kilic contact
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
University of Health Sciences, Antalya Training and Research Hospital
Antalya, Muratpaşa
About this study
Official title: The Effect of Paravertebral Block, Intertransverse Block, and Erector Spinae Plane Block on Postoperative Opioid Consumption and Pain Scores in Video-assisted Thoracic Surgery: a Prospective Observational Study
This present study aims is to compare the effects of ultrasound-guided paravertebral block, intertransverse process block, and erector spinae plane block on postoperative opioid consumption, and pain scores in patients undergoing VATS.
Read the detailed description
Video-assisted thoracic surgery (VATS) has become increasingly popular in Thoracic Surgery due to faster recovery and less postoperative pain compared to thoracotomy. However, although VATS has been reported to cause less postoperative pain than thoracotomy, it has also been shown to significantly increase the risk of acute and chronic postoperative pain, which negatively impacts postoperative pain recovery. Inadequate postoperative pain management can reduce the quality of a patient's recovery and increase the risk of postoperative pulmonary complication. Therefore, controlling pain in patients undergoing VATS is key to ensuring early mobilisation, and minimising the risk of pulmonary complications. Regional anaesthesia techniques are an important part of multimodal analgesia approach in patients undergoing VATS. The aim of the present study is to compare the effects of ultrasound-guided regional anaesthesia techniques on postoperative opioid consumption, and pain scores in patients undergoing VATS.
- Conditions
- Thoracic Surgery, Videoassisted Thoracoscopic Surgery,One-lung Ventilation, Regional Anaesthesia, Postoperative Analgesia, Pain Score
- Being tested
- Paravertebral block group, İntertransverse process block group, Erector spinae plane block group
- Keywords
- videoassisted thoracoscopic surgery, regional anaesthesia, postoperative analgesia, chronic pain, quality of recovery
- Medical subject headings
- Chronic Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Paravertebral block groupOther
Before the surgery, ultrasoud-guided paravertebral block will be performed before the surgery under standart anaesthesia monitoring
İntertransverse process block groupOther
Before the surgery, ultrasoud-guided intertransverse process block will be performed before the surgery under standart anaesthesia monitoring
Erector spinae plane block groupOther
Before the surgery, ultrasoud-guided erector spinae plane block will be performed before the surgery under standart anaesthesia monitoring
| Study group | Role | What they receive |
|---|---|---|
| Paravertebral block group | Before the surgery, ultrasoud-guided paravertebral block will be performed Receives: Other: Paravertebral block group | |
| İntertransverse process block group | Before the surgery, ultrasoud-guided intertransverse process block will be performed Receives: Other: İntertransverse process block group | |
| Erector spinae plane block group | Before the surgery, ultrasoud-guided erector spinae plane block will be performed Receives: Other: Erector spinae plane block group |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative opioid consumption
All patients will receive a standard patient analgesia (PCA) protocol after operation. The postoperative opioid consumption will only be recorded.
Measured: 24 hours
Secondary outcomes (2)
Postoperative Numerical Rating Scale (NRS) pain scores
The postoperative pain intensity will be assessed with the Numerical Rating Scale (NRS) score (0=no pain; 10=most severe pain).
Measured: postoperative 24 hours
Chronic pain
Patients will be telephoned 3 months after the surgery and the presence, localization, intensity of the pain , its character, and its relation with rest and/or activity will be recorded by asking only verbally.
Measured: 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 May 2026
- Study start4 May 2026
- Primary completion4 Oct 2026 (estimated)
- Study completion4 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Thoracic SurgeryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 96 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Antalya Training and Research Hospital
- Sponsor type
- Other government
- Responsible party
- Sponsor
- Investigators
- Sadik Ozmen, Principal investigator, University of Health Sciences, Antalya Training and Research HospitalBatuhan Kılıc, Principal investigator, University of Health Sciences, Antalya Training and Research HospitalHacer Boztepe Yesilcay, Principal investigator, University of Health Sciences, Antalya Training and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07578545
- Sponsor's protocol ID
- 7/24
- Status last verified
- Apr 2026
- First submitted
- 21 Apr 2026
- Last updated
- 11 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Supphapipat K, Samerchua A, Leurcharusmee P, Lapisatepun P, Pipanmekaporn T, Konkarn N, Prapussarakul K, Jinadech T, Wanvoharn M. Single- versus Multiple-Injection Intertransverse Process Block for VATS: A Randomized Trial on Dermatomal Sensory Blockade. J Pain Res. 2025 Sep 15;18:4791-4800. doi: 10.2147/JPR.S545731. eCollection 2025.
PubMed 40978546Sandeep B, Huang X, Li Y, Xiong D, Zhu B, Xiao Z. A comparison of regional anesthesia techniques in patients undergoing video-assisted thoracic surgery: A network meta-analysis. Int J Surg. 2022 Sep;105:106840. doi: 10.1016/j.ijsu.2022.106840. Epub 2022 Aug 24.
PubMed 36030040
Study at a glance
From the registry record, last updated by the sponsor on 11 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Paravertebral Block, Intertransverse Block, and Erector Spinae Plane Block on Postoperative Opioid Consumption and Pain Scores in Video-assisted Thoracic Surgery: a Prospective Observational Study
- ClinicalTrials.gov ID
- NCT07578545
- Acronym / sponsor ID
- 7/24
- Conditions
- Thoracic Surgery, Videoassisted Thoracoscopic Surgery,One-lung Ventilation, Regional Anaesthesia, Postoperative Analgesia, Pain Score
- Keywords
- videoassisted thoracoscopic surgery, regional anaesthesia, postoperative analgesia, chronic pain, quality of recovery
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 96 participants (estimated)
- Lead sponsor
- Antalya Training and Research HospitalOther government
- Study start
- 4 May 2026 (actual)
- Primary completion
- 4 Oct 2026 (estimated)
- Study completion
- 4 Nov 2026 (estimated)
- First posted
- 11 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This present study aims is to compare the effects of ultrasound-guided paravertebral block, intertransverse process block, and erector spinae plane block on postoperative opioid consumption, and pain scores in patients undergoing VATS.
Detailed description
Video-assisted thoracic surgery (VATS) has become increasingly popular in Thoracic Surgery due to faster recovery and less postoperative pain compared to thoracotomy. However, although VATS has been reported to cause less postoperative pain than thoracotomy, it has also been shown to significantly increase the risk of acute and chronic postoperative pain, which negatively impacts postoperative pain recovery. Inadequate postoperative pain management can reduce the quality of a patient's recovery and increase the risk of postoperative pulmonary complication. Therefore, controlling pain in patients undergoing VATS is key to ensuring early mobilisation, and minimising the risk of pulmonary complications. Regional anaesthesia techniques are an important part of multimodal analgesia approach in patients undergoing VATS. The aim of the present study is to compare the effects of ultrasound-guided regional anaesthesia techniques on postoperative opioid consumption, and pain scores in patients undergoing VATS.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Paravertebral block group | – | Other: Paravertebral block groupBefore the surgery, ultrasoud-guided paravertebral block will be performed |
| İntertransverse process block group | – | Other: İntertransverse process block groupBefore the surgery, ultrasoud-guided intertransverse process block will be performed |
| Erector spinae plane block group | – | Other: Erector spinae plane block groupBefore the surgery, ultrasoud-guided erector spinae plane block will be performed |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- It is planned to include ASA score I-III adult patients who are planned to undergo elective VATS
Key inclusion criteria (4 listed)
- aged 18-75 years
- American Society of Anaesthesiology (ASA) score I-III
- body mass index (BMI) <35kg/m2
- scheduled for elective VATS
Key exclusion criteria (9 listed)
- ASA score ≥4
- BMI ≥35 kg/m2
- declining to give written informed consent
- controendications for block application
- inability to undergo block application
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Paravertebral block groupBefore the surgery, ultrasoud-guided paravertebral block will be performed before the surgery under standart anaesthesia monitoring | Other | Paravertebral block group |
| İntertransverse process block groupBefore the surgery, ultrasoud-guided intertransverse process block will be performed before the surgery under standart anaesthesia monitoring | Other | İntertransverse process block group |
| Erector spinae plane block groupBefore the surgery, ultrasoud-guided erector spinae plane block will be performed before the surgery under standart anaesthesia monitoring | Other | Erector spinae plane block group |
Primary outcome
Postoperative opioid consumption
Time frame: 24 hours
All patients will receive a standard patient analgesia (PCA) protocol after operation. The postoperative opioid consumption will only be recorded.
2 secondary outcomes
Postoperative Numerical Rating Scale (NRS) pain scores
Time frame: postoperative 24 hours
Chronic pain
Time frame: 3 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 May 2026.
- Background: PubMed 40978546Supphapipat K, Samerchua A, Leurcharusmee P, Lapisatepun P, Pipanmekaporn T, Konkarn N, Prapussarakul K, Jinadech T, Wanvoharn M. Single- versus Multiple-Injection Intertransverse Process Block for VATS: A Randomized Trial on Dermatomal Sensory Blockade. J Pain Res. 2025 Sep 15;18:4791-4800. doi: 10.2147/JPR.S545731. eCollection 2025.
- Background: PubMed 36030040Sandeep B, Huang X, Li Y, Xiong D, Zhu B, Xiao Z. A comparison of regional anesthesia techniques in patients undergoing video-assisted thoracic surgery: A network meta-analysis. Int J Surg. 2022 Sep;105:106840. doi: 10.1016/j.ijsu.2022.106840. Epub 2022 Aug 24.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Batuhan Kilic contact
Sadik Ozmen principal investigator
University of Health Sciences, Antalya Training and Research Hospital
Batuhan Kılıc principal investigator
University of Health Sciences, Antalya Training and Research Hospital
Hacer Boztepe Yesilcay principal investigator
University of Health Sciences, Antalya Training and Research Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Thoracic Surgery and Videoassisted Thoracoscopic Surgery,One-lung Ventilation, run by Antalya Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 11 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Sadik Ozmen (+905324205282, sadikozmen@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative opioid consumption (time frame: 24 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07578545, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 May 2026.