Clinical trials: Muscle Activation, open to volunteers
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
ICU Acquired Weakness, Muscle Atrophy
Improved Muscle Metabolism by Combination of Muscle Activation and Protein Substitution ( IMEMPRO )
Intensive Care Unit Acquired Weakness (ICUAW) describes muscle weakness that occurs in around 40% of patients during an intensive care stay.
- Conditions
- ICU Acquired Weakness, Muscle Atrophy, Energy Malnutrition Protein, Quality of Life
- Trial name
- NCT05919940
- Testing
- Dietary Supplement: additional substitution of protein, Neuromuscular electrical stimulation, Early Mobilization
- Where
- 4 sites in Austria, Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Knee Osteoarthristis, Knee Pain Arthritis
Stimulation of Peripheral Afferents to Reduce Muscle Inhibition at the Knee
Knee osteoarthritis is a leading cause of disability, and the muscle weakness that limits walking in this population arises not only from the joint itself but from afferent signals that inhibit motor drive to the thigh muscle…
- Conditions
- Knee Osteoarthristis, Knee Pain Arthritis, Knee Pain Chronic
- Trial name
- SPARK (NCT07832669)
- Testing
- Peripheral Electrical Stimulation (PES), Paired Pulse Electrical Stimulation (ppES)
- Volunteers
- 50 people
- Sponsor
- Northeastern University
Stroke
EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke
The purpose of this study is to develop and test if upper limb task practice and muscle activity training improve upper limb function in stroke survivors.
- Trial name
- GAM (NCT05628324)
- Testing
- practice muscle activation patterns, task practice
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Trapeziometacarpal Osteoarthritis
Thumb Muscle Activation During Different Activities of Daily Living in Thumb Base Osteoarthritis and Healthy Controls
The aim of this study is to investigate whether there are differences in muscle activation of the first dorsal interosseous (FDI) and the abductor pollicis longus (APL) between individuals with and without thumb…
- Trial name
- NCT07866703
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Non-specific Neck Pain, Playing Related Musculoskeletal Disorders
Kinematics and Muscle Activation of Scapula in Upper String Players With Neck Pain
This study will analyze and compare scapular kinematics and muscle activation patterns between upper string musicians with and without neck pain during arm elevation and playing tasks (open strings, scales, musical pieces)…
- Trial name
- NCT07448857
- Testing
- motion capture system, surface electromyography
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Anterior Cruciate Ligament Injuries, Knee Injuries
Effects of Early Rehabilitation Using Blood Flow Restriction and/or Surface Electromyography Biofeedback on Quadriceps Activation and Strength After Anterior Cruciate Ligament Reconstruction: A Multicenter Randomized Controlled Trial
Many patients experience quadriceps inhibition after anterior cruciate ligament (ACL) reconstruction, delaying strength recovery, hindering return to sport, and potentially increasing the risk of re-injury.
- Conditions
- Anterior Cruciate Ligament Injuries, Knee Injuries, Muscle Weakness
- Trial name
- NCT07145606
- Testing
- Standard Rehabilitation, Blood Flow Restriction (BFR) Training, sEMG Biofeedback
- Where
- 4 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- Haute Ecole ARC Sante
Postural Malalignment, Forward Head Posture
Virtual Reality Versus Traditional Exercise on EMG Activity in Postural Malalignment
This study aims to investigate the immediate effects of virtual reality (VR)-based exercise compared with traditional Active free exercise on trapezius muscle activation in adults with and without postural malalignment.
- Conditions
- Postural Malalignment, Forward Head Posture, Rounded Shoulder Posture
- Trial name
- EMG (NCT07854678)
- Testing
- Virtual reality exercise, Active free Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hofstra University
Intensive Care Unit Acquired Weakness, Critical Illness
Locomotor Muscle Oxygenation and Activation During Acute Interval Compared to Constant-load Bed-cycling Exercise
Up to 60% of patients admitted to the Intensive Care Unit (ICU) with a prolonged stay in the ICU develop complications such as intensive care unit acquired weakness (ICUAW) characterized by limb and respiratory muscle weakness.
- Trial name
- NCT05279547
- Testing
- Constant-load bed-cycling exercise, Interval bed-cycling exercise
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
Sports Physical Therapy, Injury;Sports
Inspiratory Muscle Activation and Post-Exercise Recovery in Professional Football Players
Respiratory muscles play a fundamental role in sports performance. Fatigue of these muscles induces changes in maximal inspiratory pressure and autonomic nervous system activity, thereby compromising the athlete's recovery…
- Trial name
- NCT07373158
- Testing
- Inspiratory muscle activation via phrenic nerve modulation, Inspiratory muscle activation via threshold device
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Cerebral Palsy (CP), Cerebral Palsy
Dorsal Root Electrical Stimulation in Children With Cerebral Palsy
The goal of this clinical trial is to evaluate whether dorsal root electrical stimulation could reduce spasticity in children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy (CP), Cerebral Palsy, Spasticity, Spasticity Due to Cerebral Palsy
- Trial name
- NCT07715006
- Testing
- Constant Current Stimulator, Cadwell Guardian System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Martin Piazza
Intensive Care Units (ICUs)
Body Lateralization and Its Effects on Respiratory Drive, Ventilation, and Pulmonary Aeration in Critically Ill Patients
The goal of this quasi-experimental study is to investigate how different body positions, performed through Automatic Lateralization Therapy, affect respiratory drive, ventilation, and pulmonary aeration in critically ill adult…
- Trial name
- LATLUNG (NCT07323472)
- Testing
- Automatic Lateralization Therapy, Supine Positioning
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Pernambuco
Chronic Shoulder Pain
Structure and Function of the Upper Trapezius and Its Role in Chronic Shoulder Pain: an Investigation of Kinematics, Morphology, Muscle Quality and Activation Distribution
Prior research has explored factors influencing muscle activation, including muscle thickness, fear avoidance beliefs (kinesiophobia), and somatosensory integration.
- Trial name
- NCT06472349
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Cerebral Palsy (CP)
Targeted Muscle Activation During Strength Training for Children With CP
Cerebral palsy (CP) is the most common cause of physical disability in children and is associated with muscle weakness, spasticity, and impaired motor control.
- Trial name
- TACT-CP (NCT07800221)
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Muscular Dystrophy, Duchenne Muscular Dystrophy
Follow-up Study on Female Carriers With DMD Gene Variants
Background Duchenne and Becker muscular dystrophies are X-linked recessive allelic disorders caused by mutations of the dystrophin gene on chromosome Xp21.
- Conditions
- Muscular Dystrophy, Duchenne Muscular Dystrophy, Becker Muscular Dystrophy
- Trial name
- NCT05715957
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 103 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis
Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery
The proposed study seeks to understand how the cervical spinal cord should be stimulated after injury through short-term physiology experiments that will inform a preclinical efficacy trial.
- Conditions
- Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
- Trial name
- NCT06701422
- Testing
- Intraoperative stimulation of the cervical spinal cord
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Columbia University
Fatigue
Alterations in Spiking Following Muscle Fatigue in Volleyball Players
This study aims (1)to investigate the effects of repetitive functional overhead movements targeting shoulder and scapular muscles on glenohumeral and scapular kinematics and muscle activation during the arm cocking and…
- Trial name
- NCT07687550
- Testing
- Upper Extremity Muscle Fatigue Protocol
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Neuromodulatory Effects of TSCS and FES in Lower Limbs
Ultrasound for Quantifying Muscle Activation Elicited by Spinal Cord Stimulation and Functional Electrical Stimulation
Transcutaneous (non-invasive) spinal cord stimulation (tSCS) has been shown to facilitate volitional motor activity in patients with spinal cord injury.
- Trial name
- NCT07206797
- Testing
- Functional Electrical Stimulation, Transcutaneous (Non-Invasive) Spinal Cord Stimulation, Ultrasound
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Patellofemoral Pain (PFPS)
INFLUENCE OF SELECTED POSITIONS ON HIP ABDUCTORS STRENGTH AND ACTIVATION IN PATELLOFEMORAL PAIN SYNDROME IN MALES
The study aims to explore the effect of body position (side-lying versus standing) on hip abductors muscle strength and activation in individuals with and without PFPS and then to compare these measures between the two groups in…
- Trial name
- PFPS (NCT07305610)
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
A 3-day Course for CFS/ME
Chronic fatigue syndrome/Myalgic encephalomyelitis (CFS/ME) can be a serious and disabling condition with a heavy symptom burden and low function. Work disability is common, and social life dramatically affected.
- Trial name
- NCT05236465
- Testing
- A 3-day course, Waiting list
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology