Clinical trials: Minor
Stroke, Acute, Cerebrovascular Disorders
Therapy Evaluation in Patients With Minor Stroke and Large Vessel Occlusion
This multicenter registry study, which record the therapy strategy and follows up these acute ischemic stroke (AIS) patients with low NIHSS and large vessel occlusion (LVO), is intended to provide the important data for therapy…
- Conditions
- Stroke, Acute, Cerebrovascular Disorders, Brain Diseases, Central Nervous System Diseases
- Trial name
- TEMPOS (NCT06633809)
- Testing
- Immediate endovascular therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sir Run Run Shaw Hospital
Surgery, Breast Cancer
Chronic Pain and Minor Breast Cancer Surgery
Breast cancer is the most frequent in women. Early diagnosis and recent treatments have improved overall mortality. However, chronic pain (pain lasting more than 3 months after surgery) remains a public health problem with impact…
- Conditions
- Surgery, Breast Cancer, Pain, Postoperative, Pain, Chronic
- Trial name
- DCPO Sein (NCT03912948)
- Where
- France
- Volunteers
- 205 people
- Sponsor
- Institut Claudius Regaud
Head Trauma
Immunemodulation in Patients With Minor Head Injury
The purpose of this study is to try to prove the worth of the two (2) Serum Proteins S-100 Beta and NSE in combination with a diagnostic algorithm to help to establish diagnosis in patients with minor head injury.
- Trial name
- MHI (NCT00622778)
- Where
- Austria
- Volunteers
- 130 people
- Sponsor
- Medical University of Vienna
Coagulation; Intravascular, Craniocerebral Trauma
PREVACT : Preventive REversal of Vitamine K Antagonist in Minor Craniocerebral Trauma
The occurence of a minor craniocerebral trauma in patients receiving vitamine K antagonist treatment leads to a high risk of bleeding.
- Conditions
- Coagulation; Intravascular, Craniocerebral Trauma, Haemorrhage
- Trial name
- PREVACT (NCT01961804)
- Testing
- Reversion
- Where
- 21 sites in France
- Volunteers
- 202 people
- Sponsor
- University Hospital, Angers
Athletic Injuries
Safety Study of Flector Patch in Children With Minor Soft Tissue Injuries
The primary purpose of this study is to determine whether Flector Patch is safe for use in children. The secondary purpose is to assess blood levels of diclofenac, the active ingredient in Flector Patch.
- Trial name
- NCT02132247
- Testing
- Diclofenac hydroxyethylpyrrolidine
- Where
- 10 sites in United States
- Volunteers
- 104 people
- Sponsor
- IBSA Institut Biochimique SA
Minor Ischemic Stroke
Efficacy and Safety of Reperfusion Therapy for Minor Ischemic Stroke in China
Acute ischemic stroke is the most common type of stroke in China, accounting for 69.6% -72.8% of new strokes. In recent years, the proportion of mild stroke (NIHSS ≤ 5 points) has gradually increased, exceeding 50%, and the…
- Trial name
- NCT07322835
- Where
- China
- Volunteers
- 5,400 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Preleukemia, Myeloproliferative Disorders
Minor Histocompatibility Vaccination After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignancies
This is a clinical research study designed to evaluate whether the administration of a vaccine to patients after transplant consisting of a minor histocompatibility antigen (mHag peptide) mixed with G-CSF (a drug intended to…
- Conditions
- Preleukemia, Myeloproliferative Disorders, Lymphoma, Myeloma
- Trial name
- NCT00943293
- Testing
- Fludarabine, Melphalan, Campath
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Chicago
Major Depressive Disorder, Minor Depressive Disorder
Evaluation of a Stepped Care Approach to Manage Depression in Diabetes
The study examines the efficacy of a stepped care approach for depressed diabetes patients (first study objective). 256 patients with diabetes and comorbid subthreshold or clinical depression will be randomly assigned to either a…
- Conditions
- Major Depressive Disorder, Minor Depressive Disorder, Sub-Threshold Depression, Diabetes Mellitus
- Trial name
- Ecce_homo (NCT01812291)
- Testing
- Step 1: Diabetes-Specific CBT (5 group sessions), Step 2: Depression-Specific CBT (6 single sessions), Step 3: Referral to Psychotherapist and/or Psychiatrist
- Where
- Germany
- Volunteers
- 260 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Minor Stroke, Non-disabling Stroke
Stroke School -Including Physical Exercise, Patient Education and Individual Follow-up Sessions
In a randomized controlled trial the effect of 12 weeks of cross-sectorial physical exercise combined with patient education and individual follow-up session is investigated in patients with minor stroke or non-disabling stroke.
- Conditions
- Minor Stroke, Non-disabling Stroke, Transient Ischemic Attack
- Trial name
- NCT04945174
- Testing
- Cardiorespiratory exercise combined with patient education and individual follow-up sessions
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev Hospital
Recurrent Aphthous Ulcer, Recurrent Aphthous Stomatitis
Effectiveness of Recurrent Aphthous Stomatitis Mouthwash System for the Treatment of Oral Ulcers
The purpose of the present research is to evaluate the efficacy of a gel formulation for a total treatment of 14 days for the treatment of traumatic or aphthous oral ulcers.
- Trial name
- RASMA (NCT07121361)
- Testing
- Mouthwash Product, Control
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Shoulder Pain, Pain, Postoperative
Interscalene vs Infraspinatus-teres Minor (ITM) Interfascial Block in Shoulder Surgery
Postoperative pain is important following arthroscopic shoulder surgery. Postoperative effective pain treatment provides early mobilization and shorter hospital stay.Ultrasound (US)-guided brachial plexus blocks such as…
- Conditions
- Shoulder Pain, Pain, Postoperative, Surgical Procedure, Unspecified
- Trial name
- NCT06844630
- Testing
- Preoperative block application (İntersclane Block), Preoperative block application (Infraspinatus-teres minor interfascial block)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kadem Koc
Osteoarthritis of the Shoulder
Reverse Shoulder Arthroplasty With or Without Concomitant Latissimus and Teres Major Transfer for Shoulder Pseudoparalysis With Teres Minor Dysfunction
The overall objective of this study is to compare the clinical benefit and safety of two different surgical techniques of primary reverse total shoulder arthroplasty for the treatment of shoulder pseudoparalysis from chronic…
- Trial name
- NCT01697865
- Testing
- Transfer group, Control group
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Critical Limb Ischemia (CLI)
Efficacy, Tolerability and Safety of Intramuscular Injections of PLX PAD for the Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization
This will be a randomized, placebo-controlled, parallel group, multicenter, Phase III study.The study aims to evaluate the Efficacy, Tolerability and Safety of Intramuscular Injections of PLX PAD for the Treatment of Subjects…
- Trial name
- NCT03006770
- Testing
- PLX-PAD
- Where
- 57 sites in United States, Bulgaria and 7 more
- Volunteers
- 213 people
- Sponsor
- Pluristem Ltd.
Diabetes Mellitus, Amputation Stumps
Phototherapy in DM Amputation Ulcers.
Diabetes mellitus is a major public health problem and it is estimated that 300 million individuals will be affected by the year 2030.
- Conditions
- Diabetes Mellitus, Amputation Stumps, Diabetic Foot
- Trial name
- NCT02883751
- Testing
- LED, Control group
- Where
- Brazil
- Sponsor
- University of Nove de Julho
Anesthesia, Amputation; Traumatic, Leg, Lower
Anaesthetic Technique for Minor Lower Limb Amputation Surgery (ATLLAS)
Major lower limb amputation is recognised as a significant cause of morbidity and mortality. In the United Kingdom, 30-day in-hospital mortality is up to 8.7%.
- Trial name
- ATLLAS (NCT07244627)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- University Hospitals of North Midlands NHS Trust
Stroke, Acute
Improving Follow up Care for People After Minor Stroke
The goal of this feasibility study is to ascertain if this follow-up programme of care can feasibly be implemented within a healthcare system with people after minor stroke.
- Trial name
- NCT05897905
- Testing
- Personalised, holistic follow-up appointments underpinned by self determination theory
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Imperial College Healthcare NHS Trust
Minor Traumatic Brain Injury, Treatment by Antiplatelet
Interest of S100B Protein for Patient Victim of Minor Traumatic Brain Injury and Treated by Antiplatelet
All the patients admitted in emergency department for minor traumatized cranial, with antiplatelet therapy, can be included, after checked inclusion and non inclusions criterias.
- Trial name
- PETEChIA (NCT03780062)
- Testing
- S100B protein dosing
- Where
- 4 sites in France
- Volunteers
- 720 people
- Sponsor
- Poitiers University Hospital
Transient Ischemic Attack, Minor Ischemic Stroke
Dabigatran Treatment Following Transient Ischemic Attack and Minor Stroke
Objective: Demonstrate the safety of early use of dabigatran following TIA/minor stroke. Background: Although aggressive antithrombotic therapy has been shown to reduce the number of new ischemic events following stroke/TIA, this…
- Trial name
- DATAS (NCT01769703)
- Testing
- Dabigatran 110/150 mg BID
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- University of Alberta
Ischemic Attack, Transient
Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial
A transient ischemic attack (TIA) is a transient episode of neurological dysfunction caused by focal brain, spinal cord, or retinal ischemia, without acute infarction. An ischemic stroke is a cerebral infarction.
- Trial name
- POINT (NCT00991029)
- Testing
- Clopidogrel
- Where
- 210 sites in United States, Australia and 8 more
- Volunteers
- 4,881 people
- Sponsor
- University of California, San Francisco
Malocclusion of Anterior Teeth
Evaluation of Self-ligating Brackets Plus Minor Surgery in Treating Crowded Cases of Malocclusion
Patients at the Orthodontic Department of University of Damascus Dental School will be examined and subjects who meet the inclusion criteria will be admitted then the initial diagnostic records (diagnostic gypsum samples …
- Trial name
- NCT03647241
- Testing
- Self-Ligating Brackets, Traditionally-Ligated Brackets, Corticotomy
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University