Clinical trials: Meniscus; Degeneration
Metabolic Syndrome
Calorie Restricted Diet and Exercise
Calorie-restricted(CR) diet and exercise were effective to reduce Metabolic syndrome(MetS), however, its effect on knee functions for MetS patients with degenerate meniscus lesions(DMLs) was still poorly investigated.
- Trial name
- NCT05092178
- Testing
- calorie restricted diet and exercise, exercise alone
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Jingzhou
Meniscal Degeneration, Osteoarthritis, Knee
Comparing Different Types of Physical Therapy for Treating People With a Meniscal Tear and Osteoarthritis
Knee osteoarthritis is a disabling problem affecting over 15 million adults in the United States. Many people who have knee arthritis also experience painful meniscal tears.
- Trial name
- TeMPO (NCT03059004)
- Testing
- TeMPO Home Exercise Program, Motivational SMS Messages, In-Clinic Topical Therapy
- Where
- 4 sites in United States
- Volunteers
- 879 people
- Sponsor
- Brigham and Women's Hospital
Chronic Meniscal Injury
Mesenchymal Stromal Cells for Degenerative Meniscus Injury
The present proposal has the objective to assess whether the addition of autologous ex vivo expanded mesenchymal stromal cells (XCEL-M-ALPHA) to the conventional meniscal injury rehabilitation program is contributing in creating…
- Trial name
- NCT02033525
- Testing
- XCEL-M-ALPHA and standard rehabilitation, Rehabilitation
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Banc de Sang i Teixits
Anterior Cruciate Ligament Injuries, Meniscus Tear
Magic Angle Direction Imaging (MADI) ACL Study
This study will be conducted to see if a new Magnetic Resonance Imaging (MRI) scanner could give additional information or help view the body in a different way.
- Trial name
- MADI (NCT07366619)
- Testing
- Magnetic Resonance Imaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Metabolic Syndrome, Meniscus; Degeneration
Metabolic Syndrome and Degenerate Meniscus Tears
The aim is to determine the outcomes of calorie-restricted diet and exercise intervention; libitum diet and waiting list control; early arthroscopic partial meniscectomy(APM) or delayed APM effect on MetS patients with Degenerate…
- Trial name
- NCT04837456
- Testing
- Calorie restricted diet and exercise intervention, libitum diet and waiting list control group, Early arthroscopic partial menisectomy group
- Where
- China
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Jingzhou
Meniscus Tear, Knee Injuries
Investigation of the Effectiveness of Neuromuscular Exercise Program Accompanied With Degenerative Meniscal Tear
The aim of the study was to investigate the effect of exercise program added to the treatment on physical function, postural balance, muscle strength, pain and gait in individuals with meniscal damage.
- Trial name
- NCT06657586
- Testing
- neuromuscular exercises, conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medipol University Hospital
Meniscus Lesion
Meniscal INfiltration of Corticosteroid Guided With Ultra Sonography
The value of corticosteroid infiltration of the meniscus wall in the therapeutic strategy is not clearly defined: the data in the literature on the effectiveness of corticosteroid infiltration are heterogeneous and of low level…
- Trial name
- MINUS (NCT06527235)
- Testing
- ultrasound-guided betamethasone infiltration of the meniscal wall
- Where
- France
- Volunteers
- 152 people
- Sponsor
- University Hospital, Toulouse
Meniscus; Degeneration, Knee Osteoarthritis
NUsurface Implant Registry
The purpose of this active post-market surveillance clinical registry study is to further characterize the therapeutic effect, the long-term safety and effectiveness of the NUsurface® meniscus implant in the real-world…
- Conditions
- Meniscus; Degeneration, Knee Osteoarthritis, Knee Pain Chronic
- Trial name
- NIR (NCT03953846)
- Where
- 6 sites in Belgium, Germany and 2 more
- Volunteers
- 36 people
- Sponsor
- Phoenix Kinetics
Osteoarthritis, Knee, Meniscus; Degeneration
Knowledge Translation and Exercise for Degenerative Meniscal Tears and Early Osteoarthritis: KNEE-DEeP Study
Knee pain due to a degenerative meniscal tear (DMT) or early osteoarthritis (OA) is a frequent presentation in middle-aged and older adults.
- Trial name
- KNEE-DEeP (NCT06576557)
- Testing
- KNEE-DEeP intervention- Knowledge translation and exercise for early degenerative knee pain
- Where
- Ireland
- Volunteers
- 36 people
- Sponsor
- University of Limerick
Degenerative Meniscal Tear
Surgical or Exercise Therapy on Patients With Degenerative Meniscus Tears
This study is conducted as a collaboration between NAR, Orthopedic Department, Oslo University Hospital,Ullevaal, Hjelp24Nimi Oslo, Martina Hansens Hospital Norway, and University of Southern Denmark, Odense, Denmark.
- Trial name
- OMEX (NCT01002794)
- Testing
- Arthroscopic partial menisectomy, Supervised neuromuscular and strength training
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Knee Medial Meniscus Tears
Physical Therapy vs Arthroscopic Partial Meniscectomy
The purpose was to assess knee function outcomes between physical therapy and arthroscopic partial menisectomy(APM) for Metabolic syndrome(MetS) patients with degenerative meniscus lesions(DMLs) during 12 month follow up.
- Trial name
- NCT05655429
- Testing
- physical therapy, arthroscopic partial meniscectomy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shenzhen People's Hospital
Degenerative Meniscus Tear
The Benefit of Arthroscopic Partial Meniscectomy in Middle-Aged Patients
BACKGROUND Osteoarthritis (OA) is the most common form of arthritis and the knee is one of the most affected joints. The meniscus plays an important role in the development of knee OA.
- Trial name
- SLAMSHAM (NCT01264991)
- Testing
- Arthroscopic partial meniscectomy
- Where
- 2 sites in Denmark
- Volunteers
- 41 people
- Sponsor
- Slagelse Hospital
Osteoarthritis, Knee, Meniscus; Degeneration
High Tibial Osteotomy With/Without Arthroscopy.
This study will compare Hight Tibial Osteotomy with or without arthroscopically repair intra-articular knee lesions in patients with early stages of Osteoarthritis.The purpose of this study is evaluate if addition of arthroscopy…
- Trial name
- NCT05128851
- Testing
- HTO, Arthroscopy treatment, Micro fractures
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
Degenerative Disease, Meniscus Tear
The Video-Based Exercise Programs in Degenerative Meniscus Tears
This randomized controlled trial aims to investigate the efficacy of the video-based exercise programs in patients with degenerative meniscus tears.
- Conditions
- Degenerative Disease, Meniscus Tear, Knee Pain Swelling
- Trial name
- NCT05266365
- Testing
- The video-based exercise (VBE), The standard exercise (SE), The hybrid exercise (HE)
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Istanbul University - Cerrahpasa
Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear
Clinical Efficacy of Exosome in Degenerative Meniscal Injury
Comparison of intra-articular administration of synovial fluid-derived mesenchymal stem cells-derived exosomes with synovial fluid-derived mesenchymal stem cells on the same patient.
- Conditions
- Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear, Meniscus Lesion, Meniscus; Degeneration
- Trial name
- KNEEXO (NCT05261360)
- Testing
- SF-MSC-EX, SF-MSC
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Eskisehir Osmangazi University
Knee Osteoarthritis, Meniscus Tear
Effects of Kinesiotaping and Physiotherapy in Grade 2 Osteoarthritis Following Degenerative Meniscal Tears
Degenerative meniscal tears are a common cause of osteoarthritis commonly diagnosed in football players and are considered a major risk factor for the development of knee osteoarthritis.
- Trial name
- NCT06227078
- Testing
- Kinesiotaping
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- Gopal Nambi
Metabolic Syndrome, Meniscus Lesion
Metabolic Syndrome and Degenerative Meniscus Lesions Related Knee Function
Studies have suggested that Obese patients with metabolic syndrome(MetS)were correlated with knee joint degeneration and osteoarthritis.
- Conditions
- Metabolic Syndrome, Meniscus Lesion, Obesity, Abdominal, Knee Arthritis
- Trial name
- NCT04921202
- Testing
- Metabolic syndrome and meniscus injuries
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Jingzhou
Meniscus Lesion, Pain
Pulsed Electromagnetic Field Therapy (PEMT) in Patients With Degenerative Meniscus Lesions
Pulse Electromagnetic Field Therapy (PEMT) is effective in the treatment of many diseases, especially musculoskeletal system diseases, due to its analgesic effect with the effect of induced currents, and also its…
- Trial name
- NCT06692816
- Testing
- Rehabilitation
- Volunteers
- 80 people
- Sponsor
- Afyonkarahisar Health Sciences University
Meniscus Lesion
Arthroscopic Partial Meniscectomy Time Window
The purpose was to assess knee function outcomes between early arthroscopic partial meniscectomy(APM) and delayed APM for patients with degenerative meniscus lesions(DMLs)
- Trial name
- NCT05655442
- Testing
- early APM, delayed APM
- Sponsor
- Shenzhen People's Hospital
Meniscus; Degeneration
Efficacy of Telerehabilitation in Patients With Degenerative Meniscal Injury
The aim of the study is to compare the home exercise program performed with video-based telerehabilitation in patients with degenerative meniscal injury, and the home exercise program performed with one-on-one training in the…
- Trial name
- NCT05233839
- Testing
- Telerehabilitation, Paper Based Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Muğla Sıtkı Koçman University