Degenerative DiseaseNCT05266365
The Video-Based Exercise Programs in Degenerative Meniscus Tears
A study testing The video-based exercise (VBE), The standard exercise (SE) and The hybrid exercise (HE) in people with Degenerative Disease and Meniscus Tear, run by Istanbul University - Cerrahpasa at 1 site in Turkey (Türkiye).
Trial summary
This randomized controlled trial aims to investigate the efficacy of the video-based exercise programs in patients with degenerative meniscus tears. Read more about this study
- Who is it for?
- Ages 40 to 65 years
- Conditions the study is for
- Degenerative Disease, Meniscus Tear, Knee Pain Swelling
- What is being tested?
- The video-based exercise (VBE), The standard exercise (SE) and The hybrid exercise (HE)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 81 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Apr 2022to 5 Jan 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Being aged between 40 and 65 years
- Having the degenerative meniscus tear in at least one knee
- Having body mass index in the range of 18-30 kg/m2
- Feeling the pain that lasts for at least 2 months
- Having grade 1 or grade 2 degenerative meniscal tear diagnosed by an orthopedic specialist according to the MRI results
- Having the activity level is between 1 and 5 according to the Tegner Activity Scale
- Having access to the internet via a computer or smartphone
- Having the ability to read and write Turkish
Who cannot join
- Having undergone arthroscopic partial meniscectomy surgery due to degenerative meniscal tear
- Participating in a physiotherapy program for degenerative meniscal tear in the last 12 weeks
- Have received steroid injections in the last 6 months
- Accompanying conditions such as injury to the surrounding ligaments, congenital anomaly in the affected knee, coxarthrosis and spinal stenosis
- Presence of any systemic disorder that may affect assessment parameters
- Failure to cooperate with assessments
- Any vision or hearing problem that would prevent them from adapting to the assessment
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Istanbul University-Cerrahpasa
Istanbul, Bakırkoy, 34147
About this study
Official title: Investigation of the Efficacy of Video-Based Exercise Programs in Degenerative Meniscus Tears
This randomized controlled trial aims to investigate the efficacy of the video-based exercise programs in patients with degenerative meniscus tears.
Read the detailed description
To investigate the efficacy of video-based exercise programs, voluntary patients with degenerative meniscus tears aged 40-65 years will be randomly assigned to three groups: the hybrid exercise group (HEG), the video-based exercise (VBE) group, and the standard exercise (SE) group. Interventions will be delivered over 16 sessions (twice a week for 8 weeks). The patients will be assessed at baseline and at the end of the 8-week intervention. Pain during activity, at rest, and at night will be assessed using the Visual Analog Scale (VAS). Active range of motion will be evaluated using a digital goniometer. Isometric muscle strength will be measured with a handheld dynamometer. The Knee Injury and Osteoarthritis Outcome Score (KOOS) will evaluate functional status and symptoms. The Western Ontario Meniscal Evaluation Tool (WOMET) will assess health-related quality of life. Adherence to the exercise program and the Global Rating of Change Scale will be evaluated.
- Conditions
- Degenerative Disease, Meniscus Tear, Knee Pain Swelling
- Being tested
- The video-based exercise (VBE), The standard exercise (SE), The hybrid exercise (HE)
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
The video-based exercise (VBE)Other
An 8-week exercise program will be implemented as part of the conservative treatment for degenerative meniscal tears. The physiotherapist will prepare an instructional video that provides a detailed explanation and demonstration of each exercise. Patients will watch this video at home and perform the exercises according to the video instructions.
The standard exercise (SE)Other
An 8-week exercise program used in conservative treatment of degenerative meniscus tears will be performed.
An exercise program will be performed at the clinic.
The hybrid exercise (HE)Other
An 8-week exercise program will be implemented as part of the conservative treatment for degenerative meniscal tears using a hybrid telerehabilitation model. For the home-based component, the physiotherapist will prepare an instructional video that includes a detailed description and demonstration of each exercise. Patients will watch this video at home and perform the prescribed exercises by following the instructions provided in the video. In addition to the home program, patients will also participate in supervised exercise sessions conducted in the clinical setting.
| Study group | Role | What they receive |
|---|---|---|
| The Video-based exercise (VBE) group | Experimental | Each subject in the video-based exercise group (only video-based intervention) will receive a treatment protocol consisting of stretching, strengthening, and functional exercises for the knee and hip. Receives: Other: The video-based exercise (VBE) |
| The standard exercise (SE) group | Active comparator | Each subject in the standard exercise group (only clinic-based intervention) will receive a treatment protocol consisting of stretching, strengthening, and functional exercises for the knee and hip. Receives: Other: The standard exercise (SE) |
| The hybrid exercise (HE) group | Experimental | Each subject in the hybrid exercise group (video-based and clinical-based interventions) will receive a treatment protocol consisting of stretching, strengthening, and functional exercises for the knee and hip. Receives: Other: The hybrid exercise (HE) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Knee Injury and Osteoarthritis Outcome Score (KOOS)
Short-term and long-term symptoms and function will be assessed with the Knee injury and Osteoarthritis Outcome Score (KOOS) that is developed as an extension of the WOMAC Osteoarthritis Index. The score is a percentage score from 0 to 100, 0 representing extreme problems and 100 representing no problems.
Measured: Baseline
Secondary outcomes (9)
Knee Injury and Osteoarthritis Outcome Score (KOOS)
Short-term and long-term symptoms and function will be assessed with the Knee injury and Osteoarthritis Outcome Score (KOOS) that is developed as an extension of the WOMAC Osteoarthritis Index. The score is a percentage score from 0 to 100, 0 representing extreme problems and 100 representing no problems.
Measured: At the end of 8-week intervention
Visual Analogue Scale (VAS)
Pain intensity will be measured using the visual analogue scale (VAS). The participants will be asked to indicate their perceived pain at rest, during activity and at night on the 10 cm line between no pain and terrible pain. The score will be determined by measuring the distance on 10 cm line using a ruler. The higher scores indicate an higher level of pain.
Measured: Baseline
Visual Analogue Scale (VAS)
Pain intensity will be measured using the visual analogue scale (VAS). The participants will be asked to indicate their perceived pain at rest, during activity and at night on the 10 cm line between no pain and terrible pain. The score will be determined by measuring the distance on 10 cm line using a ruler. The higher scores indicate an higher level of pain.
Measured: After 8-week intervention
Active Range of Motion
Active knee range of motion including flexion and extension will be measured described by the American Academy of Orthopaedic Surgeons (AAOS) using a digital goniometer.
Measured: Baseline
Active Range of Motion
Active knee range of motion including flexion and extension will be measured described by the American Academy of Orthopaedic Surgeons (AAOS) using a digital goniometer.
Measured: At the end of 8-week intervention
Muscle Strength
Isometric muscle strength will be measured with a handheld dynamometer for knee flexors and extensors. The process will be repeated three times in each direction, with the average value recorded.
Measured: Baseline
Muscle Strength
Isometric muscle strength will be measured with a handheld dynamometer for knee flexors and extensors. The process will be repeated three times in each direction, with the average value recorded.
Measured: At the end of the 8-week intervention
Western Ontario Meniscal Evaluation Tool (WOMET)
The health-related quality of life related to degenerative meniscal tear will be used with the WOMET, which is a disease-specific tool designed to evaluate health-related quality of life in patients with meniscal pathology. The WOMET contains sixteen items addressing three domains: nine items addressing physical symptoms; four items addressing disabilities due to sports, recreation, work, and lifestyle; and three items addressing emotions. The best and least symptomatic score is 0, and the highest and most symptomatic score possible is 1600.
Measured: Baseline
Western Ontario Meniscal Evaluation Tool (WOMET)
The health-related quality of life related to degenerative meniscal tear will be used with the WOMET, which is a disease-specific tool designed to evaluate health-related quality of life in patients with meniscal pathology. The WOMET contains sixteen items addressing three domains: nine items addressing physical symptoms; four items addressing disabilities due to sports, recreation, work, and lifestyle; and three items addressing emotions. The best and least symptomatic score is 0, and the highest and most symptomatic score possible is 1600.
Measured: At the end of the 8-week intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Mar 2022
- Study start1 Apr 2022
- Primary completion1 Apr 2025
- Study completion5 Jan 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Degenerative DiseaseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 81 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Istanbul University - Cerrahpasa
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Tansu Birinci, Istanbul University - Cerrahpasa
- Investigators
- Tansu Birinci, PhD, PT, Principal investigator, Istanbul University - Cerrahpasa
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05266365
- Sponsor's protocol ID
- 107
- Status last verified
- Nov 2025
- First submitted
- 28 Feb 2022
- Last updated
- 21 Nov 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Efficacy of Video-Based Exercise Programs in Degenerative Meniscus Tears
- ClinicalTrials.gov ID
- NCT05266365
- Acronym / sponsor ID
- 107
- Conditions
- Degenerative Disease, Meniscus Tear, Knee Pain Swelling
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 81 participants (estimated)
- Lead sponsor
- Istanbul University - CerrahpasaUniversity, hospital or other
- Study start
- 1 Apr 2022 (actual)
- Primary completion
- 1 Apr 2025 (actual)
- Study completion
- 5 Jan 2026 (estimated)
- First posted
- 4 Mar 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial aims to investigate the efficacy of the video-based exercise programs in patients with degenerative meniscus tears.
Detailed description
To investigate the efficacy of video-based exercise programs, voluntary patients with degenerative meniscus tears aged 40-65 years will be randomly assigned to three groups: the hybrid exercise group (HEG), the video-based exercise (VBE) group, and the standard exercise (SE) group. Interventions will be delivered over 16 sessions (twice a week for 8 weeks). The patients will be assessed at baseline and at the end of the 8-week intervention. Pain during activity, at rest, and at night will be assessed using the Visual Analog Scale (VAS). Active range of motion will be evaluated using a digital goniometer. Isometric muscle strength will be measured with a handheld dynamometer. The Knee Injury and Osteoarthritis Outcome Score (KOOS) will evaluate functional status and symptoms. The Western Ontario Meniscal Evaluation Tool (WOMET) will assess health-related quality of life. Adherence to the exercise program and the Global Rating of Change Scale will be evaluated.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| The Video-based exercise (VBE) group | Experimental | Other: The video-based exercise (VBE)Each subject in the video-based exercise group (only video-based intervention) will receive a treatment protocol consisting of stretching, strengthening, and functional exercises for the knee and hip. |
| The standard exercise (SE) group | Active comparator | Other: The standard exercise (SE)Each subject in the standard exercise group (only clinic-based intervention) will receive a treatment protocol consisting of stretching, strengthening, and functional exercises for the knee and hip. |
| The hybrid exercise (HE) group | Experimental | Other: The hybrid exercise (HE)Each subject in the hybrid exercise group (video-based and clinical-based interventions) will receive a treatment protocol consisting of stretching, strengthening, and functional exercises for the knee and hip. |
Who may qualify
- Ages
- 40 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- Being aged between 40 and 65 years
- Having the degenerative meniscus tear in at least one knee
- Having body mass index in the range of 18-30 kg/m2
- Feeling the pain that lasts for at least 2 months
- Having grade 1 or grade 2 degenerative meniscal tear diagnosed by an orthopedic specialist according to the MRI results
Key exclusion criteria (7 listed)
- Having undergone arthroscopic partial meniscectomy surgery due to degenerative meniscal tear
- Participating in a physiotherapy program for degenerative meniscal tear in the last 12 weeks
- Have received steroid injections in the last 6 months
- Accompanying conditions such as injury to the surrounding ligaments, congenital anomaly in the affected knee, coxarthrosis and spinal stenosis
- Presence of any systemic disorder that may affect assessment parameters
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| The video-based exercise (VBE)An 8-week exercise program will be implemented as part of the conservative treatment for degenerative meniscal tears. The physiotherapist will prepare an instructional video that provides a detailed explanation and demonstration of each exercise. Patients will watch this video at home and perform the exercises according to the video instructions. | Other | The Video-based exercise (VBE) group |
| The standard exercise (SE)An 8-week exercise program used in conservative treatment of degenerative meniscus tears will be performed. An exercise program will be performed at the clinic. | Other | The standard exercise (SE) group |
| The hybrid exercise (HE)An 8-week exercise program will be implemented as part of the conservative treatment for degenerative meniscal tears using a hybrid telerehabilitation model. For the home-based component, the physiotherapist will prepare an instructional video that includes a detailed description and demonstration of each exercise. Patients will watch this video at home and perform the prescribed exercises by following the instructions provided in the video. In addition to the home program, patients will also participate in supervised exercise sessions conducted in the clinical setting. | Other | The hybrid exercise (HE) group |
Primary outcome
Knee Injury and Osteoarthritis Outcome Score (KOOS)
Time frame: Baseline
Short-term and long-term symptoms and function will be assessed with the Knee injury and Osteoarthritis Outcome Score (KOOS) that is developed as an extension of the WOMAC Osteoarthritis Index. The score is a percentage score from 0 to 100, 0 representing extreme problems and 100 representing no problems.
9 secondary outcomes
Knee Injury and Osteoarthritis Outcome Score (KOOS)
Time frame: At the end of 8-week intervention
Visual Analogue Scale (VAS)
Time frame: Baseline
Visual Analogue Scale (VAS)
Time frame: After 8-week intervention
Active Range of Motion
Time frame: Baseline
Active Range of Motion
Time frame: At the end of 8-week intervention
Muscle Strength
Time frame: Baseline
Muscle Strength
Time frame: At the end of the 8-week intervention
Western Ontario Meniscal Evaluation Tool (WOMET)
Time frame: Baseline
Western Ontario Meniscal Evaluation Tool (WOMET)
Time frame: At the end of the 8-week intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Nov 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Tansu Birinci, PhD, PT principal investigator
Istanbul University - Cerrahpasa
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing The video-based exercise (VBE), The standard exercise (SE) and The hybrid exercise (HE) in people with Degenerative Disease and Meniscus Tear, run by Istanbul University - Cerrahpasa at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 21 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Knee Injury and Osteoarthritis Outcome Score (KOOS) (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Nov 2025.