Clinical trials: Language Disorders
Alzheimer's Disease, MCI Due to AD
Language, Speech and Motor Function in MCI Due to AD and Alzheimer's Disease
The goal of this observational cross-sectional study is to explore the characteristics of language, speech, and motor function in persons with Mild Cognitive Impairment due to Alzheimer's disease ("MCI due to AD") and persons…
- Conditions
- Alzheimer's Disease, MCI Due to AD, Dementia Alzheimers
- Trial name
- NCT06508268
- Testing
- GAITRite walkway system OR 4-meter walking speed test, Jamar hand dynamometer, Picture description task
- Where
- Netherlands
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hanze University of Applied Sciences Groningen
Healthy Ageing, Cognitive Decline
Fitness, Ageing, and Bilingualism (FAB): The Benefits of Regular Exercise and Bilingualism for Language Abilities in Healthy Ageing.
This project investigates the relative benefits of regular physical activity and bilingualism for ameliorating cognitive decline in healthy ageing, with a particular focus on language function.
- Conditions
- Healthy Ageing, Cognitive Decline, Cardiorespiratory Fitness
- Trial name
- FAB (NCT07443189)
- Testing
- Home-Based HIIT
- Where
- 2 sites in Norway, United Kingdom
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- University of Agder
Stroke, Ischemic, Aphasia
pBFS-guided cTBS Over the Superior Temporal Gyrus for Aphasia After Ischemic Stroke
The objective of this trial is to evaluate the effectiveness and safeness of continuous Theta Burst Stimulation (cTBS) over the right Superior Temporal Gyrus (STG), guided by personalized Brain Function Sector (pBFS) technology…
- Trial name
- NCT05999318
- Testing
- active continuous Theta Burst Stimulation
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Changping Laboratory
Anxiety, Parents
Limited-English Proficiency (LEP) Virtual Reality (VR) Study
The purpose of this study is to determine if non-invasive distracting devices (Virtual Reality headset) are more effective than the standard of care (i.e., no technology based distraction) for preventing anxiety in parental and…
- Conditions
- Anxiety, Parents, Language
- Trial name
- NCT03689868
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University
Stuttering, Adult, Stuttering, Childhood
Transcranial Alternating Current Stimulation (tACS) in Stuttering
The purpose of this study is to investigate how mild, noninvasive electrical brain stimulation affects speech relevant brain areas, which may in turn affect speech fluency and speaking-related brain activity in people that…
- Conditions
- Stuttering, Adult, Stuttering, Childhood, Stuttering, Developmental
- Trial name
- NCT06740968
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Stroke, Aphasia
Links Between Motor Abilities and Language Ability Deficits in Patients With Post-stroke Aphasia
Aphasia is a language disorder that affects oral and written expression and/or comprehension. It's one of the most disabling consequence of stroke.
- Trial name
- MOTOLANG-AVC (NCT05776368)
- Testing
- Syntactic comprehension battery (BCS), Montreal Cognitive Assessment (MOCA), Purdue Pegboard Test
- Where
- 3 sites in France
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Stuttering, Childhood, Stuttering
Network Connectivity and Temporal Processing in Adolescents Who Stutter
The specific purpose of this clinical trial is to compare performance on rhythm perception and production tasks between children who stutter and children who do not stutter.
- Trial name
- NCT05286151
- Testing
- Rhythm discrimination
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Autism Spectrum Disorders, Non-verbal Learning Disorder
Comparison of ABLLS-R and Portage Guide in the Development of Receptive Language Skills Autism Spectrum Disorder.
Language is the system someone uses to communicate with another person. This covers the origins and construction of words, their definitions, and the use of language in various contexts.
- Trial name
- NCT06292520
- Testing
- Portage Guide Protocol, ABLLS-R protocol
- Where
- Pakistan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Central Auditory Processing Disorder, Hearing Impaired (Partially)
A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound
The goal of this clinical trial is to determine the efficacy of Clemastine Fumarate in the presence of engineered sound to treat age-related central auditory processing disorder (CAPD).
- Conditions
- Central Auditory Processing Disorder, Hearing Impaired (Partially), Hearing, Hearing Abnormality
- Trial name
- CAPD-LOOT (NCT07304024)
- Testing
- Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Colorado, Denver
Child Development, Child Development Disorder
The Indonesian Version of Ages and Stages Questionnaire III Accuracy Compared to Bayley Scales of Infant Development III
This study aimed to evaluate the concurrent validity information of the 24-, 30-, and 36-month Indonesian ASQ-3 with the Bayley Scales of Infant and Toddler Development 3rd Edition (BSID-III) in Indonesian children.
- Conditions
- Child Development, Child Development Disorder, Development Delay, Developmental Delay
- Trial name
- NCT05408351
- Where
- Indonesia
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Aphasia, Stroke
Implementing Transcranial Direct Current Stimulation in a Rehabilitation Setting
This study looks at whether transcranial Direct Current Stimulation (tDCS) can be effectively implemented in inpatient and outpatient rehabilitation settings during routine speech therapy for people who recently had a stroke and…
- Trial name
- tDCS implement (NCT07535788)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Developmental Dyslexia, Reading Problem
Personalization of Visual Characters and Text-to-Speech (TTS) to Support Learning in Students With Reading Difficulties
Previous research has shown the importance of font type, size and spacing to facilitate text reading in dyslexia. A special automatized procedure was designed to select the most favorable parameters for both text visualization…
- Trial name
- NCT06947512
- Testing
- Seleggo Test
- Where
- 3 sites in Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Anaesthesia
Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE)
The purpose of this study is to compare three communications during peripheral intravenous catheterization and measure pain patient: one hypnotic, confusion (HYPNOSIS), an other with negative connotation (NOCEBO) and at least…
- Trial name
- KTHYPE (NCT02662322)
- Testing
- Hypnotic communication, negative connotation communication, neutral connotation communication
- Where
- 3 sites in Belgium, France
- Volunteers
- 294 people
- Sponsor
- Rennes University Hospital
TCM Constitution Theory
Research on an Intelligent Health Recommendation System for Chronic Disease Comorbidity Integrating TCM
1. Construct a Traditional Chinese Medicine (TCM) constitution database, clarify the distribution patterns of TCM constitution in populations with comorbid "three-high" conditions (hypertension, hyperlipidemia, and hyperglycemia)…
- Trial name
- NCT07308366
- Testing
- Multimodal AI Models
- Volunteers
- 195 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Aphasia
Based on the Spatio-temporal Coding Characteristics of Frontotemporal Network, This Paper Explores the Mechanism of Five-tone Speech Training in Reshaping Language Fluency Function.
To explore the mechanism of five-tone speech training in reshaping language fluency function and the clinical efficacy of aphasia language function, daily communication ability and communication efficiency based on the temporal…
- Trial name
- NCT07329751
- Testing
- Traditional Chinese Medicine Five-Tone Therapy, Melodic Intonation Training, Standard speech therapy; Routine medical treatment; Health education
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fujian University of Traditional Chinese Medicine
Aphasia, Traumatic Brain Injury
Narrative Comprehension by People With Acquired Brain Injury
The purpose of this two phase study is to evaluate comprehension by people with acquired brain injury. The phase 1 portion of the study will examine comprehension of narrative paragraphs under 3 conditions: (a) written text only…
- Trial name
- NCT03309930
- Testing
- Comprehension Acquired Brain Injury
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Miami University
Developmental Language Disorders, Language Development
Understanding the Predictive Factors and the Neurocognitive Basis of Developmental Language Disorder
For most children, language acquisition might appear like an effortless phenomenon, mostly arising from informal daily interaction with their surrounding people.
- Trial name
- NCT04253600
- Testing
- Risk profile screening questionnaire, Investigation of the neural correlates of DLD using Magnetic Resonance Imagery (MRI), Online investigation of predictive factors associated with DLD and LANCOM app development
- Where
- 2 sites in Belgium
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Thyroid Cancer, Large Language Models
Evaluation of an Artificial Intelligence-enabled Clinical Assistant to Support Thyroid Cancer Management
This study aims to evaluate the clinical feasibility of adopting artificial intelligence (AI)-based models to improve clinical management of thyroid cancer.
- Trial name
- NCT07234539
- Testing
- AI-enabled clinical assistant
- Where
- 2 sites in Hong Kong
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Breast Cancer
Research on the Development and Validation of Personalized Exercise Prescriptions for Breast Cancer Patients Based on Large Language Models
The goal of this observational study is to develop and evaluate a large language model (LLM)-based decision support system for exercise prescription in breast cancer patients, aiming to provide personalized decision-making…
- Trial name
- NCT07619781
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Autism Disorder, Language Development Disorders
Rural Autistic Individuals - Supporting Expression
This research study investigates how hand gestures can support language comprehension and communication skills of hearing speaking, non-speaking, and/or minimally verbal individuals with Autism Spectrum Disorders (ASD), who are…
- Conditions
- Autism Disorder, Language Development Disorders, ADHD, Typical Development
- Trial name
- RAISE (NCT07054866)
- Testing
- Speech-Gesture combinations
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montana State University
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