Clinical trials: Iron Deficiencies
Anemia, Iron Deficiency, Iron Overload
Ethnic Differences in Iron Absorption (FeGenes)
This study aims to; 1) investigate population differences in iron absorption between East Asians and Northern Europeans; 2) assess population differences in hormonal and biochemical determinants of Fe absorption between East…
- Trial name
- FeGenes (NCT04198545)
- Where
- 2 sites in United States
- Volunteers
- 515 people, healthy volunteers welcome
- Sponsor
- Cornell University
Anemia, Iron Deficiency, Iron Overload
Heme and Non-heme Iron Intakes, Gut Microbiota, and Influence on Host Iron Absorption
The FeMicrobiome study will evaluate gut microbiome features and their relationships with dietary iron absorption in healthy adults.
- Trial name
- FeMicrobiome (NCT06146608)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cornell University
Iron Deficiency Anemia
Effect of Vitamin D Supplementation Added to Iron Therapy in Children With Iron Deficiency Anemia
This randomized controlled trial will evaluate the effect of two vitamin D3 supplementation regimens, administered in addition to oral iron therapy, on hematological and iron status in children aged 6-60 months with confirmed…
- Trial name
- NCT07892170
- Testing
- Elemental iron, Vitamin D3 2000 IU/day, Vitamin D3 400 IU/day
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- AlFayhaa General Hospital
Fatigue, Low Mood
A Study to Evaluate the Effects of a Beef Liver Supplement on Energy, Mood, and Mental Clarity
This is a randomized, triple-blind, placebo-controlled clinical trial evaluating the effects of the Ancestral Supplements Grass Fed Beef Liver oral supplement on energy, mood, and mental clarity over 12 weeks.
- Conditions
- Fatigue, Low Mood, Mental Clarity, Iron Deficiency
- Trial name
- NCT07892911
- Testing
- Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ancestral Supplements, LLC
Iron Deficiency Anemia in Pregnancy, Iron Deficiency in Pregnancy
Safety and Efficacy of Iron Prophylaxis With on Iron Homeostasis in Healthy Pregnant Women
The clinical study aims to evaluate the effect of iron supplementation in preventing the onset of Iron Deficiency Anemia during pregnancy.
- Trial name
- NCT07884617
- Testing
- Iron plus folic acid, Folic acid
- Where
- Italy
- Volunteers
- 162 people
- Sponsor
- IBSA Farmaceutici Italia Srl
Postpartum Fatigue, Iron Deficiency Anemia
Maternal Fatigue After Postpartum Anemia Treatment With Intravenous Ferric Carboxymaltose and Oral Iron Therapy
Postpartum Anemia is common after childbirth and may contribute to tiredness and reduced wellbeing in mothers.This randomized controlled trial will compare two treatments for postpartum iron deficiency:intravenous ferric…
- Trial name
- MFI20 (NCT07880314)
- Testing
- INTRAVENOUS FERRIC CARBOXYMALTOSE, oral iron therapy
- Where
- Pakistan
- Volunteers
- 134 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Heart Failure With Preserved Ejection Fraction, Iron Deficiency
IV Iron Therapy for Older Adults With Heart Failure With Preserved Ejection Fraction and Iron Deficiency
This randomized, double-blind, placebo-controlled clinical trial evaluates intravenous ferric derisomaltose in older adults with HFpEF and iron deficiency.
- Trial name
- INFUSE-HFpEF (NCT07686692)
- Testing
- Ferric derisomaltose
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Iron Deficiency Anemia Treatment
Alternate-Day vs. Once-Daily Oral Iron Supplementation in Iron Deficiency Anemia (IDA)
The goal of this clinical trial is to compare the effectiveness and tolerability of two different oral iron regimens in adults with iron deficiency anemia (IDA).
- Trial name
- NCT07014371
- Testing
- Ferrous Fumarate Oral Tablet
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Iron Deficiency Anaemia in Childbirth, Iron Deficiency
Maternal Iron Deficiency and Childhood Health
The aim of this prospective observational cohort study is to study maternal iron deficiency and iron deficiency anemia and the use of iron supplements in pregnancy and their impact on the health of the offspring and pregnancy…
- Conditions
- Iron Deficiency Anaemia in Childbirth, Iron Deficiency, Iron Deficiency in Pregnancy, Iron Deficiency Anemia in Pregnancy
- Trial name
- MATILDA (NCT06879080)
- Where
- Finland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
POTS - Postural Orthostatic Tachycardia Syndrome
Restoring Iron Deficiency in POTS
People with postural orthostatic tachycardia syndrome (POTS) often have low red blood cell volumes and low ferritin in their blood (a marker of iron storage in the body).
- Trial name
- NCT07197905
- Testing
- Intravenous iron
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Vanderbilt University Medical Center
Iron Deficiency Anemia
A Study of Ferric Derisomaltose Injection in Chinese Participants With Iron Deficiency Anemia Under Fasting Conditions
The goal of this clinical trial is to compare the pharmacokinetic profile of the developed drug product and reference product in participants with iron deficiency anemia under fasting condition.
- Trial name
- NCT07790562
- Testing
- Ferric Derisomaltose Injection, Ferric Derisomaltose Injection [MonoFer®]
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Sichuan Huiyu Pharmaceutical Co., Ltd
Iron Deficiency Anemia, Obesity
Iron Supplementation and Anemia After Sleeve Gastrectomy
The goal of this observational study is to learn if taking extra iron pills after weight loss surgery helps prevent low iron and anemia compared to just taking a standard multivitamin.
- Conditions
- Iron Deficiency Anemia, Obesity, Sleeve Gastrectomy
- Trial name
- NCT07397572
- Testing
- Elemental Iron, Multivitamin with Minerals
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Bleeding Disorders, Iron
Impact of IV Iron on Bleeding Symptoms in Iron Deficient Patients With Inherited Bleeding Disorders
This is a prospective, single-arm, single-center observational study evaluating the impact of intravenous (IV) iron replacement in patients with inherited bleeding disorders and iron deficiency (ferritin <50ng/dL).
- Conditions
- Bleeding Disorders, Iron, Platelet, Bleeding
- Trial name
- IRON-BD (NCT07083583)
- Testing
- IV Iron (standard of care)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nicoletta C Machin
Anemia, Iron Deficiency Anemia
Sucrosomial Vs Intravenous Iron for Preoperative Anemia
50 patients with anemia scheduled for heart surgery or procedures will be randomized to receive either oral sucrosomial iron or standard-of-care intravenous iron before surgery to see if the oral iron is as effective as…
- Trial name
- RSIVI (NCT07287371)
- Testing
- Treatment with oral sucrosomial iron, Treatment with intravenous iron
- Where
- United States
- Sponsor
- University of Rochester
Iron Deficiency, Latent Iron Deficiency
Reticulocyte Hemoglobin Equivalent (RET-He) in Early Detection of Iron Deficiency Among Blood Donors and Its Potential Impact on Donor Eligibility and Transfusion Safety
Blood donation is essential for healthcare, but repeated whole-blood donation can deplete the body's iron stores. Standard pre-donation screening relies on hemoglobin levels to ensure donor safety; however, a drop in hemoglobin…
- Conditions
- Iron Deficiency, Latent Iron Deficiency, Blood Donors, Iron Deficiency Anemia
- Trial name
- NCT07861607
- Volunteers
- 300 people
- Sponsor
- Assiut University
Chronic Heart Failure, Iron Deficiencies
Multi-center Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure
The goal of this clinical trial is to learn if the IV Iron treatment ferric derisomaltose helps in the treatment of chronic heart failure in people with iron deficiency.
- Trial name
- ICONIC-HF (NCT06929806)
- Testing
- Ferric Derisomaltose
- Where
- United States
- Volunteers
- 1,900 people
- Sponsor
- Pharmacosmos A/S
Iron Deficiencies
Impact of Two Iron Formulations on Iron Biomarkers and Quality of Life
This double-blind parallel pilot study will evaluate the safety and efficacy of two Qualia Iron formulations versus placebo in approximately 40 healthy adults (aged 18+) over a 56-day period.
- Trial name
- NCT07156526
- Testing
- Qualia Iron Version A, Qualia Iron Version B
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Qualia Life Sciences
Anemia, Intrauterine Growth Retardation
Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes
The study evaluates the efficacy of providing weekly iron-folate (IFA) supplements or Multiple Micronutrient (MM) supplements before pregnancy in increasing birth weight and duration of gestation as well as maternal and infant…
- Conditions
- Anemia, Intrauterine Growth Retardation, Preterm Delivery, Iron Deficiency
- Trial name
- NCT01665378
- Testing
- Multiple Micronutrient, Iron and Folic Acid, Folic Acid
- Where
- Vietnam
- Volunteers
- 5,011 people, healthy volunteers welcome
- Sponsor
- Emory University
Iron Absorption
The Effects of Acute Erythropoietin on Hepcidin and Dietary Iron Absorption Following Military-relevant Exercise in Energy Deficit: Pilot Study
Military personnel frequently experience declines in iron status during training and when in the field, which may compromise performance.
- Trial name
- IRON BOOST (NCT07517562)
- Testing
- Exercise test
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Iron Deficiency (ID), Heart Failure
Infusing Needed Iron to Target Insufficiency in Adults Treated for Evidence of Heart Failure
The INITIATE-HF study is a cluster randomized controlled trial that aims to find out if reminding doctors about treatment guidelines for iron deficiency in adults with heart failure who are hospitalized and have evidence of iron…
- Conditions
- Iron Deficiency (ID), Heart Failure, Heart Failure and Reduced Ejection Fraction, Heart Failure and Mildly Reduced Ejection Fraction
- Trial name
- INITIATE-HF (NCT07467668)
- Testing
- Notification Group, No Notification Group
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Kaiser Permanente