Clinical trials: Intraoperative Monitoring
Thyroid Disease, Thyroid Surgery
Continuous Lidocaine Infusion in Thyroid Surgery Using Intraoperative Neurophysiological Monitoring
Thyroid surgery is a common procedure for the treatment of thyroid tumors, nodules and other related lesions. During this procedure, intraoperative neurophysiological monitoring is used to protect the recurrent laryngeal nerves.
- Conditions
- Thyroid Disease, Thyroid Surgery, Lidocaine Infusion
- Trial name
- NCT06785987
- Testing
- Continuous Lidocaine Infusion, intermittent fentanyl infusion, Continuous remifentanil Infusion
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Surgery
Intraoperative Non-invasive Eye Movement Monitoring
For procedures involving proximity to the nerves responsible for eye movement, the need to monitor eye movement exists. The current solution is to place needles in the muscles surrounding the eye.
- Trial name
- NCT03046615
- Testing
- EEG Electrode Patch, Standard Needles
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
Cesarean Section, Postoperative Pain After Cesarean Section
Nociception Level Index Monitoring During Cesarean Section
This prospective randomized controlled trial evaluated the effect of nociception level (NOL) index-guided intraoperative analgesia on postoperative pain management in patients undergoing elective cesarean section under general…
- Conditions
- Cesarean Section, Postoperative Pain After Cesarean Section, Pain Management
- Trial name
- NOL-CS (NCT07720440)
- Testing
- Nociception Level Index Monitoring, Standard Intraoperative Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Shoulder Surgery, Regional Anesthesia Morbidity
Intraoperative Pain and Quality of Surgical Block During Shoulder Surgery Assessed by NOL Index
Postoperative analgesia for shoulder surgery is typically achieved by providing an interscalene brachial plexus block. However, a very common side effect of this block is hemi-diaphragmatic paralysis, a state which may not be…
- Trial name
- NCT04015284
- Testing
- Suprascapular Nerve Block + Posterior Cord Block, Interscalene Brachial Plexus Block
- Where
- Canada
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
Spectroscopic Assessment of Tissue Oxygenation Changes During Vascular Surgery
This study is a single-center, observational study designed to collect tissue spectrometric data related to tissue oxygenation.
- Conditions
- Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Ischemia Vascular, Tissue Ischemia
- Trial name
- NCT07786623
- Volunteers
- 30 people
- Sponsor
- Spectrocor
Thyroid Surgeries, Intraoperative Analgesic Use
qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery
The aim of this study is to evaluate the effect of using the non-invasive Conox monitor on intraoperative opioid consumption. Additionally, the study aims to assess the impact of Conox monitoring on recovery time, postoperative…
- Conditions
- Thyroid Surgeries, Intraoperative Analgesic Use, Anesthesia Depth Monitoring
- Trial name
- NCT07445659
- Testing
- Connox EEG Monitoring, standard anesthesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Hemodynamic Instability, General Anesthesia
End-eXpiratory Occlusion Test to Predict fluId REsponsiveness in the Operating Room (EXPIRE)
The purpose of the study is to evaluate the influence of different durations of the end-expiratory occlusion test to predict fluid responsiveness in mechanically ventilated patients in the operating room.
- Conditions
- Hemodynamic Instability, General Anesthesia, Surgery, Protective Mechanical Ventilation
- Trial name
- EXPIRE (NCT04399278)
- Testing
- Diagnostic Test: end-expiratory occlusion (EEO) test
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Intraoperative Neurophysiological Monitoring
Effect of Perioperative Factors on the Analgesia Nociception Index
The Analgesia Nociception Index (ANI) is a new unitless marker derived from Heart Rate Variability spectral analysis, ranging between 0 and 100 and expressing the parasympathetic tone.
- Trial name
- ANIFACT (NCT02305576)
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Caen
Intraoperative Ureter Injury
Dose-escalation Study of a Contrast Agent for Delineation of Urological Anatomy in Minimally Invasive Surgery
The purpose of this clinical trial is to study the safety and efficacy of an investigational imaging agent for delineation/visualization of urologic anatomy in the setting of minimally invasive surgery.
- Trial name
- NCT03106038
- Testing
- Nerindocianine for Injection
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Li-Cor, Inc.
Vocal Cord Paralysis, Recurrent Laryngeal Nerve
Effect of IONM on Efficacy and Safety Using Sugammadex in Thyroid Surgery
Thyroidectomy is a frequently performed surgeon by the head and neck and endocrine surgeons. In recent years, surgical techniques and technological developments have resulted in a significant reduction in complication rates.
- Trial name
- NCT03634956
- Testing
- Group B. Sugammadex sodium-IONM
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Anesthesia, Monitoring, Intraoperative
Registry Construction of Intraoperative Vital Signs and Clinical Information in Surgical Patients
Monitoring data during anesthesia of surgical patient in the operation room will be collected and stored into the registry automatically. Patients' information and preoperative assessment from medical records will be included.
- Trial name
- NCT02914444
- Where
- South Korea
- Volunteers
- 200,000 people
- Sponsor
- Seoul National University Hospital
Cerebellopontine Angle Tumor
Compare the Operating Condition of Two Levels of Muscle Relaxation on Facial Nerve MEP Monitoring in CPA Surgery
compare the operating condition of two different levels of muscle relaxation on facial nerve monitoring using transcranial motor evocked potential in CPA surgery .
- Trial name
- NCT04148534
- Testing
- Rocroniom, Non Depolarizing Muscle Relaxant
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Muhammad Magdy Gaber
Atelectasis
Role of Lung Ultrasound Imaging for Intraoperative Monitoring of Atelectasis During Laparoscopic Surgery
General anesthesia results in the development of atelectasis in the dependent areas of the lungs exposing patients to an increased risk of hypoxemia.
- Trial name
- NCT01749436
- Testing
- Lung ultrasound imaging examinations
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Perioperative Care, Hemodynamics
ImPortance of Arterial Measurement Sites (IPAMS) on Intraoperative Hemodynamic Management
The goal of this clinical trial is to demonstrate the importance of arterial pressure measurement sites during major abdominal surgeries.
- Conditions
- Perioperative Care, Hemodynamics, Monitoring Blood Pressure, Arterial Lines
- Trial name
- IPAMS (NCT06982001)
- Testing
- Brachial line guided hemodynamic management, Radial line guided hemodynamic management, Radial line catheterization
- Where
- Canada
- Volunteers
- 204 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Intraoperative Hypotension
Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) for Perioperative Hemodynamic Optimization in Patients Under General Anesthesia
This study investigates if the Hypotension Prediction Index (HPI) combined with the Assisted Fluid Management (AFM) software can improve perioperative hemodynamic management in adult patients undergoing general anesthesia.
- Trial name
- NCT07301307
- Testing
- Acumen IQ sensor with Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) software, Conventional Intraoperative Hemodynamic management
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Focal Epilepsy, Intraoperative Monitoring
Evaluation of New Flexible High-density Intra-operative ECoG Electrodes for Epilepsy Surgery. ( EpiGrid )
The objective of this prospective interventional monocentric clinical investigation is to evaluate the feasibility and performance of the flexible high-density SOFT ECoG electrode grids, manufactured by Neurosoft Bioelectronics…
- Trial name
- EpiGrid (NCT06205160)
- Testing
- SOFT ECoG subdural grid electrode
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Neurosoft Bioelectronics SA
Pain, Postoperative, Analgesia
Analgesia Nociception Index (ANI) in Intracranial Surgical Anesthesia
In our study, 75 patients aged 18-80 years, classified as ASA I-II risk groups, who underwent intracranial surgery performed by the Department of Neurosurgery at Trakya University Faculty of Medicine Hospital, were included.
- Conditions
- Pain, Postoperative, Analgesia, Supratentorial Brain Tumor, Infratentorial Neoplasms
- Trial name
- ANI (NCT06752824)
- Testing
- ANALGESIA NOCICEPTION INDEX MONITORING
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Trakya University
Target Controlled Infusion, Intracranial Neoplasm
Comparison of Opioid Consumption During TCI Guided by NOL Index or Standard Care Undergoing Intracranial Tumor Surgery
In this prospective, randomized controlled study, we hypothesized that nociception level index monitoring reduced opioid administration during surgery.
- Conditions
- Target Controlled Infusion, Intracranial Neoplasm, Opioid, Nociceptive Pain
- Trial name
- NOLopioid (NCT05732896)
- Testing
- Nociception Leve Indeks
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Turkish Society of Anesthesiology and Reanimation
Hypercarbia
The Effect of Ketamine in the Prevention of Hypoventilation in Patients Undergoing Deep Sedation Using Propofol and Fentanyl
Procedures performed under sedation have the same severity in regards to morbidity and mortality as procedures performed under general anesthesia1.
- Trial name
- NCT01825083
- Testing
- Ketamine
- Where
- United States
- Sponsor
- Northwestern University
Brain Tumor Adult, Epilepsy
WISE Cortical Strip for Intraoperative Neurophysiological Monitoring
The WIN Study is a prospective, interventional, multi-center, open-label premarket study designed to confirm the safety, performance and intended use of the WISE Cortical Strip (WCS) for CE certification purposes.
- Trial name
- WIN (NCT03731455)
- Testing
- WISE Cortical Strip
- Where
- 5 sites in Germany, Italy and 1 more
- Volunteers
- 32 people
- Sponsor
- Wise S.r.l.