Clinical trials: Intradialytic Hypotension
End Stage Renal Disease, Hypertension
Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients
Kidney failure has been recognized as one of the most costly chronic conditions among United States Veterans. Approximately 13,000 Veterans develop kidney failure each year, and most require hemodialysis initiation.
- Conditions
- End Stage Renal Disease, Hypertension, Extracellular Volume Overload, Intradialytic Hypotension
- Trial name
- NCT04163614
- Testing
- IBPS-Guided Ultrafiltration
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- VA Office of Research and Development
Exposure to Magnetic Field, Hypotension During Dialysis
Dermal Profile Analysis Using the NMR-MOUSE
The determination of fluid status in dialysis patients is a major clinical problem. In this study the NMR-MOUSE is used to determine if it can be used to non-invasively determine hydration status of the skin.
- Conditions
- Exposure to Magnetic Field, Hypotension During Dialysis, Disturbance; Balance, Fluid
- Trial name
- SHN (NCT02934009)
- Testing
- Dermal nuclear magnetic resonance (NMR)-profile measurement
- Where
- Germany
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Hypotension
Effect of Intradialytic Electrical Muscle Stimulation and Passive Leg Mobilisation on Blood Pressure and Dialysis Efficacy
Hypothesis: Intradialytic blood pressure and dialysis efficacy (in terms of urea removal) improve under electrical muscle stimulation or passive leg movement on a treadmill.
- Trial name
- NCT00328289
- Testing
- transcutaneous muscle stimulation, treadmill
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Dialysis Hypotension
Steroids on Intra-dialytic Hypotension
Symptomatic hypotension during (or immediately following) hemodialysis complicates 5 to 30 percent of all dialysis treatments and is associated with increased morbidity and mortality.
- Trial name
- NCT03465007
- Testing
- Hydrocortisone, Normal saline
- Where
- Jordan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Hemodialysis Complication
Study of Abnormalities of the Nervous System in the Occurrence of Intradialytic Arterial Hypotension
Intradialytic hypotension is a common complication of hemodialysis sessions in patients with chronic renal failure, with an estimated prevalence of 10 to 30%.
- Trial name
- SUDHEMO (NCT03990142)
- Testing
- Cutaneous conductance to chlorine by SUDOSCAN
- Where
- France
- Volunteers
- 176 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Fluid Overload and Hypertension in Hemodialysis Patients
Effect of Sodium Concentration of Priming and Rinsing Fluids on Weight Gain
Sodium loading during hemodialysis treatment is common and may contribute to increased interdialytic weight gain and hypertension.
- Trial name
- NCT01168947
- Testing
- 5% dextrose solution
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Renal Research Institute
Intradialytic Hypotension, Hemodialysis-Induced Symptoms
Timing of Intradialytic Exercise and Its Impact on Intradialytic Hypotension
The objective of this study is to compare the rate of low blood pressure events (Intradialytic Hypotension: IDH) when intradialytic exercise is performed in the first half of the hemodialysis (HD) session as compared to that when…
- Trial name
- NCT03504943
- Testing
- Early Intradialytic Exercise, Late Intradialytic Exercise
- Where
- 3 sites in Canada
- Volunteers
- 112 people
- Sponsor
- University of Manitoba
Hypotension
Blood Pressure Guided Biofeedback on Hemodialysis and the Reduction of IntraDialytic Hypotension
It is very common for hemodialysis patients to have problems with low blood pressure while on hemodialysis. Low blood pressure on dialysis is not a good thing and it is associated with an increased risk of death and…
- Trial name
- BP-RIDH (NCT01749761)
- Testing
- BioLogic RR, Hemodialysis without biofeedback
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Calgary
Intradialytic Hypotension, End-Stage Renal Disease
The Efficacy and Safety of Guilu Erxian Jiao in the Treatment of Intradialytic Hypotension
The goal of this clinical trial is to learn if Guilu Erxian Jiao, a traditional Chinese herbal medicine, can help manage intradialytic hypotension (IDH), a drop in blood pressure that occurs during hemodialysis in adults.
- Conditions
- Intradialytic Hypotension, End-Stage Renal Disease, Hemodialysis
- Trial name
- NCT06980922
- Testing
- Guilu Erxian Jiao
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Chang Gung Memorial Hospital
Hypotension During Dialysis, Dialysis Hypotension
Integrated Strategies to Prevent Intradialytic Hypotension (The DialHypot Study)
The present study is aimed at comparing different strategies of UF profiling, dialysate sodium individualization and sodium profiling (even combining one with the other) and at evaluating the effectiveness of a new UF profile…
- Trial name
- DialHypot (NCT03949088)
- Testing
- UF and Na profiling
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Parma
Intradialytic Hypotension, Hypervolemia
Pilot Study Using a Pulse Oximeter Derived Photo-plethysmographic Waveform to Guide Hemodialysis Ultrafiltration
The purpose of this study is to use the photo-plethysmographic [PPG] waveform signal to guide the dialysis and ultrafiltration [UF] of chronic maintenance hemodialysis patients, and to further the investigators understanding of…
- Trial name
- NCT02264522
- Testing
- Place dialysis chair into position 3., Decrease dialysate temperature., Decrease ultrafiltration rate by 25%.
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Intelomed, Inc.
Acute Kidney Injury, Intra-dialytic Hypotension
Low Dialysate Temperature During SLED
Objectives: This study is evaluating the hemodynamic effects of lowering the dialysate temperature in acute kidney injury (AKI) patients submitted to sustained low efficiency dialysis (SLED) in a single large center.
- Trial name
- NCT03397992
- Testing
- Changing dialysate temperature
- Volunteers
- 38 people
- Sponsor
- Washington University School of Medicine
Cardiac Complications, Signs and Symptoms
Evaluation of the Effects of L-Carnitine Injection in Patients Undergoing Hemodialysis
This is a study designed to test the hypothesis that treatment with L-carnitine will improve the quality of life and some specific symptoms and signs in patients with renal failure submitted to hemodialysis.
- Conditions
- Cardiac Complications, Signs and Symptoms, Muscle Weakness, Anemia
- Trial name
- NCT00173706
- Testing
- L-Carnitine Injection
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Acute Kidney Injury
Midodrine is Effective in Management of Intradialytic Hypotension Among Critically-ill Patients With Acute Kidney Injury
The aim of this randomized trial was to assess the efficacy of oral midodrine tablets for the management of intradialytic hypotension among critically ill patients with acute kidney injury.
- Trial name
- NCT03431194
- Testing
- midodrine
- Volunteers
- 80 people
- Sponsor
- Benha University
Intradialytic Hypotension
Safety and Benefit Study of Droxidopa to Treat Patients With Intradialytic Hypotension
In clinical trials in Japan, droxidopa has been shown to be effective in affecting blood pressure changes upon orthostatic challenge in patients with autonomic dysfunction, as well as reducing the severity and frequency of…
- Trial name
- IDH201 (NCT00657046)
- Testing
- Droxidopa
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Chelsea Therapeutics
Intradialytic Hypotension
Abdominal Compression Elastic Support (ACES)
Hemodialysis (HD) patients with end stage renal disease (ESRD) experience higher rates of cardiovascular (CV) morbidity and mortality than do the general population and many populations with other chronic diseases.
- Trial name
- ACES (NCT02159625)
- Testing
- Abdominal Compression Elastic Support
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Global Monitors, Inc.
Acute Kidney Injury, Chronic Kidney Disease Stage 5 on Dialysis
Non-invasive Assessment to Predict Tolerance to Fluid Removal on Intermittent Kidney Replacement Therapy
This prospective cohort study aim to investigate the ability of multiple types of assessments including 1) the modified Venous Excess Ultrasound (VExUS) assessment, 2) non-invasive estimation of absolute blood volume (ABV), and…
- Conditions
- Acute Kidney Injury, Chronic Kidney Disease Stage 5 on Dialysis, Chronic Kidney Failure, Intradialytic Hypotension
- Trial name
- TECHNO-HDF (NCT05270759)
- Testing
- Estimated absolute blood volume, Modified VExUS evaluation
- Where
- Canada
- Volunteers
- 93 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Intradialytic Hypotension, Immersion
Head Out Water Immersion for Hemodynamic Stability During Dialysis
Immersion to the neck before and during hemodialysis session may increase intravascular volume, potentiate the ability to ultrafiltrate excess water, with less symptoms of shock, muscle crumps etc.
- Trial name
- NCT03057392
- Testing
- immersion
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Assaf-Harofeh Medical Center
Renal Dialysis
The Effect of Food Intake During Hemodialysis on Blood Pressure
Intradialytic hypotension is one of the most common complications associated with food intake during hemodialysis. Whether patients should be allowed to eat during hemodialysis is still a moot point.
- Trial name
- NCT05405348
- Testing
- Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- melek avcı
Acute Intradialytic Hypotension
Observational Study to Assess Oxygen Saturation Predictive Power Related to Intradialytic Acute Hypotension
The aim of the present work was to analyze the short-term variability of SO2 during hemodialysis in sessions with and without hypotension to correlate the SO2 variability to hemodynamic instability.
- Trial name
- SOGLIA (NCT01759641)
- Testing
- Hypotension-prone patients
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna