Clinical trials: In-hospital Mortality
Hip Fractures, In-hospital Mortality
Mortality and Predictors of In-hospital Mortality Among Geriatric Patients With Hip Fracture
To assess the incidence of in-hospital mortality among geriatric patients with hip fractures and to identify its potential predictors
- Trial name
- NCT07873918
- Volunteers
- 141 people
- Sponsor
- Assiut University
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Aged, Home Care, Hospital-Based
Home-based Acute Care for Older Persons Initiated by the Emergency Medical and Ambulance Services - a Retrospective Observation of Effects on Healthcare Utilisation and Mortality
This observational study aims to examine outcomes of home-based acute care delivered by a mobile healthcare team in persons aged 75 years and older following an episode of acute illness.
- Conditions
- Aged, Home Care, Hospital-Based, Home Care Services, Emergency Medical Dispatch Centre
- Trial name
- NCT07472335
- Testing
- Type of care pathway
- Where
- Sweden
- Volunteers
- 5,000 people
- Sponsor
- Vastra Gotaland Region
Burn Injury, In-Hospital Mortality
Burn Mortality Prediction Scores
This retrospective observational cohort study evaluates hospitalized burn admissions treated at the Burn Center of Gaziantep City Hospital between October 2023 and February 2026.
- Trial name
- BURN-PRED (NCT07689890)
- Testing
- Retrospective Prognostic Score Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 1,082 people
- Sponsor
- Gaziantep City Hospital
Acute Pancreatitis (AP), News-2
Predictive Performance of NEWS-2 and NEWS-Calcium Scores for In-Hospital Mortality in Older Patients With Acute Pancreatitis
Acute pancreatitis is an important gastrointestinal emergency that may lead to mortality, particularly in older patients. This retrospective, single-center observational prognostic validation study aims to compare the predictive…
- Conditions
- Acute Pancreatitis (AP), News-2, Prediction of In-Hospital Mortality in Older Patients With Acute Pancreatitis
- Trial name
- NEWS (NCT07640971)
- Testing
- Retrospective Calculation of NEWS-2 Score
- Where
- Turkey (Türkiye)
- Volunteers
- 350 people
- Sponsor
- Antalya Health Sciences University
Surgery--Complications, Perioperative/Postoperative Complications
Telemedicine Notifications With Machine Learning for Postoperative Care
The ODIN-Report study will be a randomized controlled trial of the effect of providing machine learning risk forecasts to providers caring for patients immediately after surgery on serious complications.
- Conditions
- Surgery--Complications, Perioperative/Postoperative Complications, Acute Kidney Injury, Hospital Mortality
- Trial name
- ODIN-Report (NCT03974828)
- Testing
- Anesthesia Control Tower Notification
- Sponsor
- Washington University School of Medicine
Intensive Care (ICU), Age Over 80 Years
Pre-ICU Hospital Length of Stay and 30-day Mortality in the Very Old: a National Cohort of 315 042 ICU Admissions
How does waiting in hospital before intensive care affect older patients?Patients who become seriously ill are sometimes admitted to a regular hospital ward first, and only transferred to the intensive care unit (ICU) when their…
- Conditions
- Intensive Care (ICU), Age Over 80 Years, Hospital Length of Stay, Mortality
- Trial name
- NCT07571213
- Testing
- Time in hospital before ICU admission.
- Where
- Sweden
- Volunteers
- 315,042 people
- Sponsor
- Uppsala University
Home Care Services, Hospital-Based, Frailty
Rockwood Frailty Index and Survival in Hospital-at-Home Patients
Frailty is a key determinant of prognosis in older adults with complex chronic conditions and in palliative care settings. The Rockwood Frailty Index (RFI), based on the accumulation of health deficits, has demonstrated…
- Conditions
- Home Care Services, Hospital-Based, Frailty, Mortality, Palliative Care
- Trial name
- DOMMOR (NCT07529470)
- Testing
- Patients identified and followed in this cohort received scheduled supportive telephone calls every two weeks if classified in the oncologic palliative care group, and once monthly in the case of comp
- Where
- Spain
- Volunteers
- 2,610 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
AKI, Renal Replacement Therapy
Hyperoxia vs Normoxia During Cardiopulmonary Bypass
This single-center randomized controlled pilot trial evaluates the effects of intraoperative hyperoxia compared with normoxia during cardiopulmonary bypass (CPB) in adult patients undergoing elective cardiac surgery.
- Conditions
- AKI, Renal Replacement Therapy, NGAL, Arrythmia
- Trial name
- IPEROXIA (NCT07510672)
- Testing
- Hyperoxia group, Normoxia group (control)
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- University of Padova
Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection
Impact of Nurses' Behavior Change and Evidence-Based Practice Implementation on Quality Indicators in Intensive Care Units in Low- and Middle-Income Countries
Study title: Impact of nurses' behavior change and implementing evidence-based practice to improve quality indicators in intensive care units in low-and middle-income countries Background and Rationale: Quality care is crucial…
- Conditions
- Ventilator-Associated Pneumonia (VAP), Central Line-Associated Bloodstream Infection, Pressure Ulcers (Hospital-acquired Pressure Injuries), Prolonged Intensive Care Unit Length of Stay
- Trial name
- NCT07397364
- Testing
- Evidence based practices bundles of care
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Pre-surgical Anxiety, Blood Glucose Concentration
Vis Pre Surgery Medical Food Validation Study
A pre-market, confirmatory, prospective, interventional, clinical investigation to confirm the clinical safety and performance profile of Vis Pre-surgeryTM that the medical food will reduce pre and post-surgical complications…
- Conditions
- Pre-surgical Anxiety, Blood Glucose Concentration, Blood Cortisol Levels, Electrolyte Levels
- Trial name
- NCT07359222
- Testing
- Pre-surgical medical food
- Where
- India
- Volunteers
- 67 people
- Sponsor
- TM Nutrition LLC
Measles Vaccine, Hospital Admission
Measles Vaccination at Health System Contacts
In addition to protecting against measles infection, measles vaccine (MV) strengthens the individual's ability to combat infections in general - MV has beneficial non-specific effects (NSE) lowering the risk of death and…
- Conditions
- Measles Vaccine, Hospital Admission, Mortality, Non-specific (Heterologous) Effects of Vaccines
- Trial name
- NCT04220671
- Testing
- measles vaccine, Saline
- Where
- Guinea-Bissau
- Volunteers
- 5,400 people
- Sponsor
- Bandim Health Project
In-hospital Mortality, Non-COVID Deaths
Pre- vs Post-Pandemic Risk-adjusted Survival Rates in the US Hospitals
This study aims to perform a retrospective cohort study of administrative health data to understand how care delivery performance varies across US hospitals post-COVID-19 pandemic compared to the pre-pandemic performance.
- Conditions
- In-hospital Mortality, Non-COVID Deaths, Surge
- Trial name
- NCT06651645
- Testing
- COVID-19 Surge
- Where
- United States
- Volunteers
- 30,000,000 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Delirium - Postoperative, Cardiac Surgery
Lemborexant to Prevent Post-operative Delirium in Cardiac Surgery Patients
Post-operative delirium is a common complication following cardiac surgery and is associated with increased 1 year mortality. Currently there are no drug therapies to prevent delirium.
- Conditions
- Delirium - Postoperative, Cardiac Surgery, Cardiac Surgery Subjects, Orexin Antagonist
- Trial name
- PROTEX (NCT06648681)
- Testing
- Lemborexant 5 mg
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Paediatric Surgery, Perioperative/Postoperative Complications
An African, Multi-centre Evaluation of Patient Care and Clinical Outcomes for Paediatric Patients Undergoing Surgery
Access to safe surgery is a basic human right. This is highlighted by the work of the Lancet Commission on Global Surgery. There is a large burden of surgical disease in the paediatric surgical population with a large unmet need.
- Conditions
- Paediatric Surgery, Perioperative/Postoperative Complications, Perioperative Outcomes, Hospital Mortality
- Trial name
- ASOS-Paeds (NCT05061407)
- Where
- 2 sites in South Africa, Sudan
- Volunteers
- 8,625 people
- Sponsor
- University of KwaZulu
Hospital Mortality, Cancer
Death Certificate Analysis at Colombian Orinoquia: A Retrospective Observational Trial.
By hospital mortality, the health of a population is identified. Death certificates are a valuable tool in establishing causes of death.
- Conditions
- Hospital Mortality, Cancer, Chronic Disease, Non Communicable Chronic Diseases
- Trial name
- NCT05739305
- Testing
- Risk factor
- Where
- Colombia
- Volunteers
- 10,000 people
- Sponsor
- Hospital Departamental de Villavicencio
Life Quality, Hospital Mortality
Effect of Nutritional Support and Early Rehabilitation on Sepsis
Sepsis is a syndrome of life-threatening organ dysfunction caused by a dysregulated host response to infection.Acute catabolic response in critically ill patients struck by sepsis, manifested by massive protein breakdown in a…
- Trial name
- NUSPOTER (NCT05781971)
- Testing
- high protein, rehabilitation, standard protein
- Volunteers
- 1,600 people
- Sponsor
- Jinling Hospital, China
In-hospital Mortality
Association Between Administration of Dexmedetomidine and Postoperative Mortality in Hospitals
The present multicentre retrospective cohort study aimed to investigate the association between intraoperative administration of dexmedetomidine and postoperative mortality in hospitals.
- Trial name
- NCT06248346
- Testing
- Dexmedetomidine
- Volunteers
- 518,043 people
- Sponsor
- Xijing Hospital
Primary Outcome : Compare Percent CRP Reduction, Secondary Outcome : 30-day Mortality, Renal Recovery, Length of Hospital Stay
Efficacy of Convection-based HDF Compare With Diffusion-based HD in Sepsis-associated AKI
Acute kidney injury (AKI) is a common complication among patient admitted in the hospital worldwide, with estimates of prevalence ranging from less than 1% to 66%.1, 2 In critically ill patients approximately 49% were acute…
- Trial name
- NCT06227104
- Testing
- Convection-based Hemodiafiltration
- Where
- Thailand
- Volunteers
- 28 people
- Sponsor
- Ramathibodi Hospital
in Hospital Mortality, Geriatric
Prognosis of Geriatric Patients With Non-bedded Night in the Emergency Department: a Multicenter Cohort Study
Retrospective, multicenter, French cohort study. Data from patients over 75 years of age who visited the emergency department on 12 and 13 December 2022 could be collected until their discharge from hospital and for a maximum of…
- Trial name
- NoBedNight (NCT05821491)
- Where
- France
- Volunteers
- 1,598 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris