Clinical trials: Glaucoma Suspect
Glaucoma, Glaucoma, Open-Angle
Prevalence of Glaucoma and Normative Data of Ocular Biometry in Elderly Population in Bangkok
The BANMOP eye study is an ophthalmic subproject of the Bangkoknoi Model Project (BANMOP), a community-based initiative integrating electronic health databases with population surveys to sup-port context-specific health promotion…
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Glaucoma, Suspect, Glaucoma, Angle-Closure
- Trial name
- BANMOP (NCT07763288)
- Where
- Thailand
- Volunteers
- 1,470 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Primary Glaucoma, Glaucoma Suspect
Development of the Glaucoma Visual Functioning Questionnaire-40 and Its Psychometric Properties
The objective of this study is to develop and test the psychometric properties of a self-report questionaire, the Glaucoma Visual Functioning Questionnaire-40 (GVFQ-40), which was designed to measure the difficulty of daily…
- Trial name
- NCT04722861
- Testing
- GVFQ-40
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Primary Angle Glaucoma Closure Suspect
Danish Angle Closure Prevention Trial
To determine whether primary angle closure suspects (PACS) in a Caucasian population benefit from prophylactic laser iridotomy.
- Trial name
- DAP (NCT06077253)
- Testing
- Iridotomy
- Where
- 5 sites in Denmark
- Volunteers
- 242 people
- Sponsor
- University of Aarhus
Glaucoma, Ocular Hypertension
A Phase I Clinical Trial of DARC
Glaucoma is a major cause of irreversible blindness worldwide, caused by retinal nerve cell (RGC) death. This is currently identified only after significant vision loss has already occurred with an early event in, and a potential…
- Conditions
- Glaucoma, Ocular Hypertension, Glaucoma, Suspect
- Trial name
- NCT02394613
- Testing
- ANX776
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University College, London
Anesthesia, Intraocular Pressure
Establishment of an Anaesthetic Protocol for Examinations for Children With Glaucoma or Suspected Glaucoma
Correct measurement of the intraocular pressure of children with glaucoma or suspected glaucoma is essential for diagnosis and therapy.
- Conditions
- Anesthesia, Intraocular Pressure, Glaucoma, Suspect, Pediatric Glaucoma
- Trial name
- eyeBIS (NCT03972852)
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Normal Tension Glaucoma, Primary Open-angle Glaucoma
Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag Isopropyl
This study is for patients have been using prostaglandin analogue eye drops with a preservative for 3 months or more and have been diagnosed with prostaglandin-associated peri-orbital disease.
- Conditions
- Normal Tension Glaucoma, Primary Open-angle Glaucoma, Glaucoma, Suspect, Ocular Hypertension
- Trial name
- NOPAPS (NCT05279716)
- Testing
- Eybelis ophthalmic solution 0.002%
- Where
- 8 sites in South Korea
- Volunteers
- 150 people
- Sponsor
- Santen Pharmaceutical Asia Pte. Ltd.
Ocular Hypertension, Glaucoma
Effects of a Single OMT on Intraocular Pressure (IOP) in Ocular Hypertenive or Glaucoma Suspect Subjects
The hypothesis is that osteopathic manipulative treatment (OMT)will significantly reduce intraocular pressure (IOP) in individuals with ocular hypertension (OHT) and glaucoma suspect patients.
- Trial name
- OMT4OHT (NCT01864642)
- Testing
- osteopathic manipulative treatment (OMT)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Wisconsin, Madison
Glaucoma, Macular Degeneration
BCI and Evaluation of Visual and Task Performance in Subjects With Eye Diseases
The purpose of this research study is to better understand the impact of visual impairment caused by different eye diseases on the ability to perform daily activities and compare it to that in patients without eye diseases.
- Conditions
- Glaucoma, Macular Degeneration, Glaucoma Suspect, Optic Neuropathy
- Trial name
- NCT03318549
- Testing
- Visual Performance tests, Brain-computer interface
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Miami
Glaucoma
Stop Retinal Ganglion Cell Dysfunction Study
Glaucoma is a progressive disease resulting in blindness. Determining the onset of the disease, predicting its severity and the benefit of pressure lowering eye drops is key to clinical management aimed at maintaining useful…
- Trial name
- STOP-RGCD (NCT02390284)
- Testing
- Latanoprost, Bimatoprost, Travoprost
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Miami
Glaucoma
Glaucoma Laser Assessment of Stability and Sustainability
The GLASS Study is designed to help researchers learn whether repeating a non-invasive laser treatment called DSLT (Direct Selective Laser Trabeculoplasty) can better control eye pressure in patients with early-stage glaucoma or…
- Trial name
- GLASS (NCT06963684)
- Testing
- Dual-Treatment Direct Selective Laser Trabeculoplasty (DSLT)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Twin Cities Eye Consultants
Glaucoma, Open Angle, Low Risk
Effect of Negative Pressure on Pattern Electroretinography Readings
Glaucoma is a leading cause of blindness worldwide. Intraocular pressure (IOP) remains the only modifiable risk factor for glaucoma.
- Conditions
- Glaucoma, Open Angle, Low Risk, Ocular Hypertension, Glaucoma Suspect
- Trial name
- NCT04433702
- Testing
- Mercury™ Multi-Pressure Dial (MPD) Experimental Goggle
- Where
- United States
- Sponsor
- Vance Thompson Vision
Primary Open-Angle Glaucoma, Mild Stage, Glaucoma, Suspect
Effects of Prostaglandin Analogue Washout Following Long-term Therapy in Adults With Primary Open Angle Glaucoma
A target for glaucoma treatment is the intra-ocular pressure (IOP) which is lowered with medications, laser, or surgical intervention.
- Conditions
- Primary Open-Angle Glaucoma, Mild Stage, Glaucoma, Suspect, Ocular Hypertension
- Trial name
- NCT03534882
- Testing
- Discontinuation of topical prostaglandin analogue therapy
- Where
- Canada
- Volunteers
- 87 people
- Sponsor
- Cindy Hutnik
Glaucoma, Intraocular Pressure
Accuracy of Handheld and Non-contact Tonometry
Monitoring the intraocular pressure (IOP) is one of the most important tests used in follow-up among glaucoma suspects and confirmed glaucomatous patients.
- Conditions
- Glaucoma, Intraocular Pressure, Glaucoma, Suspect
- Trial name
- NCT05352906
- Testing
- Intraocular pressure
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Benha University
Glaucoma, Glaucoma, Suspect
Automated Applanation Tonometry
Goldmann Applanation Tonometry (GAT) is considered the clinical gold standard for eye pressure measurements and yet it is known to be a subjective measurement with limited repeatability and limited portability.
- Trial name
- NCT05235321
- Testing
- Standard GAT, Fixed force GAT, Upright applanating prototype
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Duke University
Glaucoma, Glaucoma, Suspect
Automated Applanation Tonometry - Updated
Goldmann Applanation Tonometry (GAT) is considered the clinical gold standard for eye pressure measurements and yet it is known to be a subjective measurement with limited repeatability and limited portability.
- Trial name
- NCT07298356
- Testing
- Standard GAT, Fixed force GAT, Upright applanating prototype
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Glaucoma, Suspect, Diabetic Retinopathy
Eye Health Intervention Study in Upper Manhattan
Individuals living in Upper Manhattan have limited access to eye care, high vision impairment rates, and poor ocular health outcomes.
- Conditions
- Glaucoma, Suspect, Diabetic Retinopathy, Cataract, Refractive Errors
- Trial name
- EYES-UM (NCT06112431)
- Testing
- Intervention, Usual Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Chronic Angle Closure Glaucoma, Primary Angle Closure
Sequential Laser Iridotomy Using Argon and Q-Switched 532 nm Frequency Doubled Neodymium Yag Laser: A Pilot Study
Sequential Laser Iridotomy uses argon and Nd:yag laser in the first and second steps, respectively. Using q-switched 532 nm laser in the second step is hypothesized to be as good and effective as the conventional Nd:yag laser…
- Conditions
- Chronic Angle Closure Glaucoma, Primary Angle Closure, Primary Angle Closure Suspect, Fellow Eyes of Acute Angle Closure Glaucoma
- Trial name
- NCT00452998
- Testing
- Q-switched fd Nd:yag in Laser Iridotomy
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Glaucoma, Glaucoma, Suspect
Reliability and Reproducibility of the Eye Check Tonometer
To investigate whether the new applanation tonometer (EyeCheck monitor) can provide intraocular pressure (IOP) measurements comparable to those of traditional tonometers such as the Goldmann applanation tonometer and the Tonopen.
- Trial name
- EyeCheck (NCT04639947)
- Testing
- EyeCheck, Traditional Tonometer (Goldmann and Tonopen)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Duke University
Glaucoma
Progression of Disease in Patients Newly Diagnosed With Glaucoma and Glaucoma Suspects Participating in the GATE Study
The purpose of this study is to measure how many patients develop worsening glaucoma in the early years (2-4 years) of routine monitoring in hospital eye services.
- Trial name
- PEG (NCT03394521)
- Testing
- Routine clinical practice
- Volunteers
- 326 people
- Sponsor
- University of Aberdeen
Diabetic Retinopathy, Retinal Vein Occlusion
Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph
Blindness can be caused by many ocular diseases, such as diabetic retinopathy, retinal vein occlusion, age-related macular degeneration, pathologic myopia and glaucoma.
- Conditions
- Diabetic Retinopathy, Retinal Vein Occlusion, Retinal Artery Occlusion, Central Serous Chorioretinopathy
- Trial name
- NCT04723160
- Testing
- Software assisted imaging diagnosis
- Where
- 5 sites in China
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Visionary Intelligence Ltd.