Clinical trials: Fractures, Bone
Hand Fractures
Repair of Extra-articular Fractures of the Metacarpals and First Phalanges of the Long Fingers
The goal of this randomized controlled trial is to compare the effectiveness, complications, and cost-effectiveness of three surgical techniques (intramedullary screw fixation, locked plating, and percutaneous pinning) for…
- Trial name
- FinXger (NCT07186829)
- Testing
- Percutaneous pinning, Locked plate, Intramedullary screw
- Where
- France
- Volunteers
- 111 people
- Sponsor
- University Hospital, Montpellier
Wrist Fracture
Wrist Reduction Intervention: Supracondylar Technique for Radial Nerve Block vs. Hematoma Block (WRIST Block Study)
The purpose of this study is to compare different types of local anesthesia-a supracondylar radial nerve block, a hematoma block, or a combination of the two-for reducing pain in people with a broken wrist (distal radius…
- Trial name
- NCT07268547
- Testing
- Supracondylar radial nerve block, Hematoma block, Combination of blocks
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Sarasota Memorial Health Care System
Non-inflammatory Degenerative Joint Disease, Rhematoid Arthritis
Tornier Perform™ Reversed Monopost Study
This study is a Multi-center, Prospective Follow-up, Non-significant risk, Post-Market Clinical Follow-Up (PMCF) study to Evaluate the Safety and Effectiveness of the Tornier Perform™ Reversed MonoPost System.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Rhematoid Arthritis, Correction of Functional Deformity, Fracture of the Humeral Head
- Trial name
- Monarch (NCT07764614)
- Testing
- Tornier Perform™ Reversed MonoPost
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Stryker Trauma and Extremities
Pain, Appendicitis
PAINED: Project Addressing INequities in the Emergency Department
Racial and ethnic inequities in health care quality have been described across a broad range of clinical settings, patient populations, and outcomes.
- Conditions
- Pain, Appendicitis, Bias, Racial, Fractures, Bone
- Trial name
- PAINED (NCT05488080)
- Testing
- Department-level audit and feedback and electronic health record-embedded clinical decision support
- Where
- United States
- Volunteers
- 22,032 people
- Sponsor
- Children's National Research Institute
Naso-Orbito-Ethmoidal, Fractures
REDUCTION ACCURACY IN NASO-ORBITO-ETHMOIDAL FRACTURES AFTER VIRTUAL REDUCTION AND FIXATION USING PRE-ADAPTED MINIPLATES
This study aims to assess the reduction accuracy of Naso-orbito-ethmoidal (NOE) fractures using pre-adapted titanium miniplates based on a virtually reduced 3D model.
- Trial name
- NCT07791095
- Testing
- pre-adapted titanium miniplates based on a virtually reduced 3D model
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Alexandria University
Postoperative Pain, Rebound Pain
Nerve Block Resolution Time Display and Pain Complaints
This randomized prospective study will evaluate whether displaying the expected nerve block resolution time on a patient's splint reduces postoperative pain-related complaints after orthopedic surgery.
- Conditions
- Postoperative Pain, Rebound Pain, Fracture
- Trial name
- NCT07887516
- Testing
- Physical display
- Volunteers
- 128 people
- Sponsor
- Medical University of South Carolina
Abdominal Pain, Isolated Extremity Fracture
Morphine or Ketamine for Analgesia
Pain is common in children presenting to the emergency department but is frequently undertreated, leading to both short- and long-term consequences.
- Conditions
- Abdominal Pain, Isolated Extremity Fracture, Pain, Pediatrics
- Trial name
- MoKA (NCT06835504)
- Testing
- Ketamine hydrochloride, Morphine sulphate
- Where
- 8 sites in United States
- Volunteers
- 1,010 people
- Sponsor
- Columbia University
Endosseous Dental Implant Failure, Accident Caused by Broken Ceramic
Full-Contour Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation Behavior
In patients who received a full-mouth implant-supported rehabilitation restored with CAD/CAM full-contour monolithic zirconia (FCMZ, without buccal ceramic veneer; veneering, if present, limited to the gingival area), what is the…
- Trial name
- FCMZ (NCT07876466)
- Testing
- Dental Implant, Monolithic Zirconia (FCMZ)
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Proximal Humerus Fracture
Study on Outcomes of Proximal Humerus Fractures
Patients undergoing either operative or non-operative treatment of proximal humerus fractures will be studied with the goal of understanding which treatment modality provides optimal post-injury outcomes.
- Trial name
- NCT07060664
- Testing
- open reduction internal fixation, intramedullary nail, reverse total shoulder arthroplasty
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Massachusetts, Worcester
Connective Tissue Disorders, Osteogenesis Imperfecta
Evaluation and Treatment of Patients With Connective Tissue Disease
This study offers evaluation and treatment of patients with a suspected connective tissue disorder. The protocol is not designed to test new treatments; rather, patients receive standard care.
- Conditions
- Connective Tissue Disorders, Osteogenesis Imperfecta, Bone Diseases, Metabolic, Melorheostosis
- Trial name
- NCT00076830
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Endosseous Dental Implant Failure, Accident Caused by Broken Ceramic
Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation Behavior
In patients rehabilitated with a full-arch (maxillary and/or mandibular) implant-supported fixed prosthesis, do three CAD/CAM zirconia framework designs - porcelain-veneered zirconia (PVZ), monolithic zirconia with buccal veneer…
- Trial name
- NCT01974362
- Testing
- Dental Implant, Monolithic Zirconia (MZ), Zirconia-Feldspathic (PVZ)
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Fracture Arm, Fracture Leg
Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms
The Accuro XV is a cart-based, bedside ultrasound instrument that incorporates new signal processing-based technologies for enhanced bone and soft-tissue imaging.
- Conditions
- Fracture Arm, Fracture Leg, Wrist Injury, Ankle Injury
- Trial name
- NCT07853768
- Testing
- Accuro XV Ultrasound Imaging System
- Where
- 10 sites in United States
- Volunteers
- 25,000 people
- Sponsor
- Rivanna Medical, Inc.
Osteoporosis Diagnosis, Bone Health
REMS vs DXA for Osteoporosis Diagnosis and Fracture Risk Prediction
This prospective, observational, comparative diagnostic study will evaluate the performance of Radiofrequency Echographic Multi Spectrometry (REMS) for the diagnosis of osteoporosis and prediction of fragility fracture risk in a…
- Conditions
- Osteoporosis Diagnosis, Bone Health, Fracture
- Trial name
- NCT07876882
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- BoneVue Diagnostics
Fall Injury, Hip Fractures
Fall, Fracture and Frailty
This project aims to improve the global outcome for an aging individual after a traumatic fall, through identifying conditions contributing to a fall and promoting recovery and rehabilitation.
- Conditions
- Fall Injury, Hip Fractures, Risk Reduction, Osteoporosis, Osteopenia
- Trial name
- FFF (NCT05712252)
- Where
- Sweden
- Volunteers
- 1,200 people
- Sponsor
- Region Skane
Atypical Femur Fracture
Quebec Registry for Atypical Femur Fractures
Bisphosphonates are recommended as first-line agents to reduce fracture risk in patients with osteoporosis and have in general an excellent safety profile.
- Trial name
- NCT02150850
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- McGill University
Nasal Bone Fracture, Ultrasound
Ultrasound-assisted Nasal Bone Fracture Reduction
Clinical Trial Abstract Nasal bone fracture is the most common traumatic disease in otorhinolaryngology, which adversely affects nasal appearance and physiological function.
- Trial name
- NCT07869563
- Testing
- Ultrasound-guided nasal bone fracture reduction, No ultrasound-guided nasal bone fracture reduction
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Primary Osteoarthritis, Secondary Osteoarthritis
Prospective Study for the Evaluation of the Cementless Anatomic Femoral Stem Minimax -Launay
This is a post-marketing surveillance on MiniMAX Stem
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Traumatic Arthritis, Rheumatoid Arthritis
- Trial name
- NCT06012656
- Testing
- MiniMAX
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Medacta International SA
Orthopaedic Fractures, Orthopaedic Trauma Fractures and Non-unions
Mindfulness in Fracture Recovery and Reduction of Opioid Reliance: Evaluating the Feasibility of Implementing a Brief, Mindfulness-based Intervention to Manage Pain and Anxiety Before and After Fracture Surgery
Breaking a bone is not only physically painful but also emotionally overwhelming. Patients often experience intense pain, anxiety, and uncertainty as they are rushed to hospital, undergo emergency treatment, and prepare for…
- Conditions
- Orthopaedic Fractures, Orthopaedic Trauma Fractures and Non-unions, Orthopaedic Trauma, Orthopaedic Surgery
- Trial name
- MIRROR (NCT07486505)
- Testing
- Mindfulness Based Intervention, Educational Recording
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Fracture, Scoliosis Idiopathic Adolescent
Opioid Analgesia Impacts on Neurological Development
Background: Pain in childhood - whether from injuries like fractures or long-term conditions like scoliosis - is often treated with opioid medicines. These drugs are effective for pain relief.
- Conditions
- Fracture, Scoliosis Idiopathic Adolescent, Traumatic Injury, Adolescent
- Trial name
- OPAL (NCT07855952)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Nottingham
Fracture
Effectiveness and Cost-effectiveness of Surgical Treatment of Humeral Shaft Fractures. Randomized Controlled Trial
Humeral shaft fractures represent 1-3% of all fractures and 20% of the humeral fractures. These fractures have historically been treated mainly conservatively with good results.
- Trial name
- NCT01719887
- Testing
- Conservative treatment, Operative treatment, Physiotherapy
- Where
- 2 sites in Finland
- Volunteers
- 82 people
- Sponsor
- Töölö Hospital