Clinical trials: Exercise Induced Muscle Damage, active
Exercise Induced Muscle Damage, Physical Activity
Walk It Off! the Influence of Physical Activity Level on the Recovery from Damaging Resistance Exercise
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS).
- Conditions
- Exercise Induced Muscle Damage, Physical Activity, Inflammation, Exercise Recovery
- Trial name
- WIO (NCT06810271)
- Testing
- Eccentric resistance exercise
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Athletic Performance, Soccer
The Effect of a Training Programme in the Variation of Fitness Parameters, Physiological, Hematological and Biochemical Indicators of Soccer Players During the Preseason Period
The goal of this study is to investigate the effects of varying friendly match-play exposure during the late pre-season on physiological, biochemical, and performance adaptations in soccer players.
- Conditions
- Athletic Performance, Soccer, Muscle Damage, Inflammation
- Trial name
- NCT07170930
- Testing
- Friendly Match-Play Exposure: extended vs. limited
- Where
- Greece
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Emmanouil D. Zacharakis
Exercise-induced Muscle Damage
Effects of Inter-Set Rest Intervals on Muscle Damage After Flywheel Exercise in Untrained Men (RCT)
This randomized parallel-group clinical trial will compare the acute effects of three different inter-set rest intervals during a single lower-limb flywheel resistance exercise session in untrained men.
- Trial name
- NCT07679971
- Testing
- Flywheel resistance exercise with 1-minute inter-set rest, Flywheel resistance exercise with 2-minute inter-set rest, Flywheel resistance exercise with 3-minute inter-set rest
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Vicosa
Insomnia, Healthy Adult
The Effect of Different rTMS Interventions on Acute Experimental Muscular Pain in Individuals Comorbid With Insomnia
Insomnia exacerbates pain sensitivity and impairs physiological recovery from acute musculoskeletal pain. Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising non-invasive neuromodulation intervention to…
- Conditions
- Insomnia, Healthy Adult, Exercise Induced Muscle Damage, Pain Sensitivity
- Trial name
- NCT07827677
- Testing
- Repetitive transcranial magnetic stimulation (rTMS) on L M1, Repetitive transcranial magnetic stimulation (rTMS) on R DLPFC
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Exercise-induced Muscle Damage
Effects of Nattokinase Supplementation on Strength Recovery and Muscle Damage Biomarkers Following Exercise-Induced Muscle Injury: A Pilot Study
This pilot study aims to investigate whether 4 weeks of nattokinase supplementation (2,000 FU/day) affects recovery following exercise-induced muscle damage in healthy adult men.
- Trial name
- NCT07836634
- Testing
- Nattokinase
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Exercise Induced Muscle Damage, Cryotherapy
Acute Cryotherapy on Musculoskeletal Function and Biomarkers
In 2020, Dubois and Esculier proposed a paradigm shift in the acute management of musculoskeletal injuries, advocating for the transition from the traditional PRICE protocol- Protect, Rest, Ice, Compression, Elevation-to the more…
- Trial name
- NCT07211412
- Testing
- Cryotherapy, Eccentric exercise-induced muscle damage
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Eccentric Hypertrophy, Muscle Damage
Comparing Two Eccentric Protocols on Muscle Damage
The purpose of this study will be to test whether a new way of weight training is more effective than typical weight training. The investigators expect that this new way will cause more exercise-induced muscle damage, which helps…
- Trial name
- NCT06992271
- Testing
- Fast Eccentric, Slow Eccentric
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Aseptic Muscle Injury
Effects of Protein and NAC Co-ingestion on Skeletal Muscle Recovery
Previous evidence suggests that though N-acetylcysteine (NAC) supplementation following eccentric exercise-induced muscle damage disrupts the skeletal muscle's repair and remodelling process at 8 days of recovery, it attenuates…
- Trial name
- PRoNAC (NCT06367413)
- Testing
- NAC, NAC + Whey Protein
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Exercise Induced Muscle Damage
Indirect Biomarkers and Exercise Induced Muscle Damage
The purpose of this study is to investigate the magnitude of changes in biomarkers of exercise-induced muscle damage following an acute bout of eccentric exercise of the knee extensors performed on an isokinetic dynamometer.
- Trial name
- NCT07503860
- Testing
- Eccentric Exercise
- Where
- Greece
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vassilis Paschalis
Exercise-induced Myocardial Damage, Right Ventricular Diastolic Dysfunction
Effects of Exogenous Ketones on Acute Changes and Recovery of the Heart Muscle After Intense Exercise.
It is well known that scar tissue on the heart muscle can cause (life-threatening) arrhythmias. However, the exact cause of this scar tissue is not entirely clear.
- Trial name
- NCT06715748
- Testing
- Ketone Monoester (KE)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Focus on Omega 3 Index on Recovery
Long-Term Omega-3 and Omega-3 Index >8%: Effects on Physiological Recovery
The Omega-3 Index measures how much of the Omega-3 fats EPA and DHA are built into red blood cell membranes. These fats are essential for health, but the body cannot make enough of them, so they must come from foods like oily…
- Trial name
- IMPROVE-8 (NCT07439601)
- Testing
- Oil Supplementation
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Delayed Onset Muscle Soreness, Exercise-Induced Muscle Damage
Mineral-Infused Clothing for Recovery From Muscle Soreness and Muscle Damage After Exercise
The goal of this clinical trial is to learn whether wearing mineral-infused clothing helps muscles recover after a hard bout of unaccustomed exercise in healthy adults aged 18 to 45 who have not done lower-body resistance or jump…
- Trial name
- PERFICT (NCT07873866)
- Testing
- Mineral-infused garment, Non-infused control garment, Muscle-damaging eccentric exercise (drop jumps)
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- StudySetGo
Exercise Induced Muscle Damage, Delayed Onset Muscle Soreness (DOMS)
Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness
The purpose of this study is to evaluate how probiotic supplementation (PS) influences post-exercise recovery in healthy, physically active young adults.
- Trial name
- NCT07219498
- Testing
- Lactobacillus casei
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Young Athletes
Effects of Manual Lymphatic Drainage and Pressotherapy on Muscle Recovery After Eccentric Exercise in Physically Active Young Adults
This randomized controlled trial aims to compare the effects of manual lymphatic drainage (MLD), intermittent pneumatic compression (IPC), and passive rest on recovery following exercise-induced muscle damage (EIMD) induced by a…
- Trial name
- LYMPH-REC (NCT07892105)
- Testing
- Manual Lymphatic Drainage, Intermittent Pheumatic Compression
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Camilo Jose Cela University