Clinical trials: Executive Functions (EF)
Executive Functions in Cerebral Palsy
Personalized Innovative Intervention Pathways to Promote EF in Children With CP
Cerebral palsy (CP) is an umbrella term, covering a group of disorders of movement and posture. It is now accepted that CP represents much more than a disorder of movements considering the frequent association with a broad range…
- Trial name
- NCT06288971
- Testing
- Self-adaption web-based software for the rehabilitation of EF and visuo-spatial abilities, Tele-rehabilitation of EF and specific cognitive processes underlying academic skills, Game-based tools for the rehabilitation of EF and motor planning
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Child Development, Executive Functions (EF)
Sharing Tales That Teach: Shared Picturebook Reading for Early Childhood Emotional and Cognitive Development
Sharing Tales That Teach is a randomised study of a shared picturebook reading programme for 4- to 5-year-old children and their primary caregivers.
- Conditions
- Child Development, Executive Functions (EF), Emotion Regulation
- Trial name
- STTT (NCT07666802)
- Testing
- Emotion-Focused Shared Picturebook Reading, Standard Dialogic Picturebook Reading
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Greenwich
ADHD, Child, Only
A Randomized Controlled Study of Family Based EF Training for Schoolage Children With ADHD
The goal of this study is to provide a new treatment approach for schoolage children with ADHD, which could facilitate the EF developing well to achieve better outcome.
- Trial name
- NCT05025501
- Testing
- Family based Executive Function Training
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Executive Functions (EF), Cognitive Development
Development of Executive Functions in Children and Adolescents: Establishment of a Reference Norm for the Assessment of Executive Functions in Ecological Settings (eEFEe Tool)
The aim of this interventional study is to develop a normative reference for the ecological assessment of executive functions in children and adolescents using the eEFEe tool.
- Conditions
- Executive Functions (EF), Cognitive Development, Normative Data
- Trial name
- DFEE (NCT07654920)
- Testing
- eEFEe Ecological Assessment and Standardized Testing
- Where
- France
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape
Attention Deficit Hyperactivity Disorder
Brain Training in Children With/At-risk for Attention-Deficit/Hyperactivity Disorder and Executive Function Impairment
The purpose of this study is to determine if different forms of child-friendly, computer-based puzzles and games ("brain training") targeting executive function (EF) skills (i.e., thinking, problem-solving) result in improvements…
- Trial name
- NCT02588365
- Testing
- Brain Training (Active), Brain Training (Passive), Brain Training (Active or Passive)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obstructive Sleep Apnea (OSA)
The Effects of Hypoxic Burden on Executive Function (EF) in Preschool Children With Obstructive Sleep Apnea
The goal of this observational study is to study the effect of hypoxic burden on executive function in preschool children aged 2-6 years who have OSA.
- Trial name
- NCT07023458
- Testing
- Brief-P
- Where
- Thailand
- Volunteers
- 72 people
- Sponsor
- Mahidol University
Cognitive Intervention to Promote Healthy Development of Executive Function (EF) Skills in Young Children
Parent-Child EF Intervention
Koronis Biomedical Technologies Corporation (KBT) is developing a cognitive intervention to promote healthy development of Executive Function (EF) skills in young children by leveraging a smartphone-based training regime designed…
- Trial name
- NCT06924307
- Testing
- Executive Function Intervention
- Where
- 2 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Koronis Biomedical Technologies
Neurofibromatosis 1 (NF1), Executive Function (Cognition)
Cognitive Intervention for Children and Adolescents With NF1
Psychological interventions have been shown to be effective for managing cognitive and mental health challenges in different patient populations.
- Conditions
- Neurofibromatosis 1 (NF1), Executive Function (Cognition), Cognitive Intervention
- Trial name
- NCT07869914
- Testing
- Unstuck and On Target!
- Volunteers
- 60 people
- Sponsor
- The Hospital for Sick Children
Executive Functions (EF), Decision Making
Effects of Cognitive Training on Executive Functions and Decision-Making in Adolescent Female Volleyball Players
This randomized controlled trial aims to evaluate the effects of a four-week tablet-based cognitive training program on executive functions and on-court decision-making performance in adolescent female volleyball players.
- Conditions
- Executive Functions (EF), Decision Making, Volleyball
- Trial name
- NCT07692698
- Testing
- Tablet-Based Cognitive Training, Routine Volleyball Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Firat University
Acquired Brain Injury
Exploring the Use of the CO-OP With Children With EF Functions Deficits Following ABI
Purpose: Acquired brain injury (ABI) in childhood are the cause of disabling motor, cognitive and behavioural disorders, with severe consequences on the later development of autonomy and learning, with long-term repercussions on…
- Trial name
- NCT04718688
- Testing
- CO-OP rehabilitation
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Hopitaux de Saint-Maurice
Autism Spectrum Disorder
Hybrid Computerized EF Training Using Virtual Human Stimuli for Autism
The goal of this pilot clinical trial is to learn the preliminary feasibility and efficacy of a home-based hybrid computerized executive function (EF) training program using social stimuli for autistic individuals.
- Trial name
- NCT07308210
- Testing
- Hybrid computerized executive function training
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- Education University of Hong Kong
Attention, Cognitive Training
Xbox-Based Exergames Versus Structured Home-Based Cognitive Training for Attention and Executive Functions in Healthy Adults
Background: Exergames are increasingly used to support cognition in older adults; however, evidence comparing exergames with non-computerized cognitive training in healthy adults remains limited.
- Conditions
- Attention, Cognitive Training, Executive Functions (EF), Xbox-based Exergames
- Trial name
- NCT07809412
- Testing
- Xbox-based exergames intervention, Structured home-based cognitive training
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medipol University
Executive Functions (EF), Microbiome
Smoothie Program for Achieving and Resilient Kids
The proposed study will examine whether eating yogurt every day can improve brain and gut health in children. Prior research suggests that yogurt may support cognitive functions like self-control, but more studies are needed to…
- Conditions
- Executive Functions (EF), Microbiome, Dietary Quality
- Trial name
- SPARK (NCT07195474)
- Testing
- Yogurt Smoothie (1 per day), Yogurt Smoothie (2 per day), Fruit Juice Control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Penn State University
ADHD
RCT of EF Family Training for P ADHD
To explore the effect of executive function family training for preschool children with ADHD, providing early social psychological intervention for aiming the core impairments of ADHD.
- Trial name
- NCT04454008
- Testing
- executive function family training, treat as usual
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Heart Defects, Congenital, Executive Dysfunction
EF Intervention in Children With Severe Congenital Heart Disease
Survival rates of children with severe congenital heart disease (CHD) have increased with ongoing medical progress over the past decades.
- Trial name
- E-FIT (NCT05198583)
- Testing
- E-Fit
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- University Children's Hospital, Zurich
Traumatic Brain Injury
VR-based EF Rehabilitation for Pediatric TBI
Childhood traumatic brain injury (TBI) poses significant impairment in children's executive functions (EFs) for moderate to severe injuries, yet interventions specifically designed for children's EF rehabilitation post-TBI and…
- Trial name
- NCT03611062
- Testing
- VR Executive Functions Training
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Massachusetts, Lowell
Congenital Heart Disease, Executive Dysfunction
Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With Critical CHD
Advances in prenatal and neonatal care have improved outcomes in children with critical congenital heart disease (CCHD). With the increase in survival, neurocognitive problems such as executive functioning (EF) impairments have…
- Conditions
- Congenital Heart Disease, Executive Dysfunction, Attention Disorder
- Trial name
- LbH (NCT06267430)
- Testing
- Kleuter Extra training program
- Where
- 3 sites in Netherlands
- Volunteers
- 103 people
- Sponsor
- Erasmus Medical Center
Executive Functions (EF), Working Memory
Beyond Aerobic Fitness: Effects of Coordination and Aerobic Exercise on Executive Functions in School-Aged Children
This randomized controlled trial aims to compare the effects of aerobic exercise and coordination-based exercise on executive functions in school-aged children aged 10 to 12 years.
- Conditions
- Executive Functions (EF), Working Memory, Selective Attention
- Trial name
- NCT07658404
- Testing
- Aerobic Exercise Program, Coordination Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Executive Functions (EF)
Boosting Executive Function With Real-class Exercise
The goal of this study is to examine the effects of acute pre-class physical exercise on executive function in real classroom settings.
- Trial name
- NCT07231536
- Testing
- Mentally active sitting, 5-minute physical exercise, 10-minute physical exercise
- Where
- China
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Shenzhen University