Obstructive Sleep Apnea (OSA)NCT07023458
The Effects of Hypoxic Burden on Executive Function (EF) in Preschool Children With Obstructive Sleep Apnea
An observational study of Obstructive Sleep Apnea (OSA), run by Mahidol University at 1 site in Thailand.
Trial summary
The goal of this observational study is to study the effect of hypoxic burden on executive function in preschool children aged 2-6 years who have OSA. The main question it aims to answer is Effect of hypoxic burden from OSA to executive function measured by BRIEF-P in preschool children.. Read more about this study
- Who is it for?
- Ages 2 to 6 years
- Conditions the study is for
- Obstructive Sleep Apnea (OSA)
- What is being tested?
- Brief-P
- How many people
- 72 participants
- Where
- 1 siteThailand
- Study dates
- 1 Mar 2025to 1 Feb 2026
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 2 to 6 years
- All sexes
- No healthy volunteers
- Child
Study population: Siriraj Hospital
Who may be able to join
- Children aged 2-6 years old with OSA
Who cannot join
- Underlying diseases : hypoventilation, neuromuscular diseases, etc.
Trial locations and contacts
1 site in 1 country.
About this study
The goal of this observational study is to study the effect of hypoxic burden on executive function in preschool children aged 2-6 years who have OSA.
The main question it aims to answer is Effect of hypoxic burden from OSA to executive function measured by BRIEF-P in preschool children..
Read the detailed description
There is no comparison group in this study Participants will performed full night polysomnography, Denver and BRIEF-P test within 3 months.
- Conditions
- Obstructive Sleep Apnea (OSA)
- Being tested
- Brief-P
- Medical subject headings
- Sleep Apnea, Obstructive
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Brief-PDiagnostic test
Executive function test in preschool children with OSA
| Study group | Role | What they receive |
|---|---|---|
| 1 | All participants in the group will undergo polysomnography, Denver test and BRIEF-P test for executive function Receives: Diagnostic Test: Brief-P |
What is being measured
The primary outcome is the main question the study is designed to answer.
Executive function from BRIEF-P test
T-scores at or below 59 are considered to be within the typical range
Measured: 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jun 2025
- Study start1 Mar 2025
- Primary completion1 Feb 2026
- Study completion1 Feb 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Obstructive Sleep Apnea (OSA)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 72 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mahidol University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sarisa Thawongit, Mahidol University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07023458
- Sponsor's protocol ID
- COA119/2025
- Status last verified
- Oct 2026
- First submitted
- 7 Jun 2025
- Last updated
- 16 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No