Clinical trials: Driving
Attention Deficit Hyperactivity Disorder
Enhancing ADHD Driving Performance With Stimulant Medication
Among children, attention-deficit/hyperactivity disorder (ADHD) is associated with an increased risk for accidents, especially bicycle and pedestrian (Leibson 2001; Jensen 1988; DiScala 1998).
- Trial name
- NCT00572026
- Testing
- Methylphenidate Transdermal System
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Virginia
ARDS, Human, Respiratory Failure
Driving Pressure and Mortality: in the Pediatric Intensive Care Unit (PICU)
Respiratory failure is one of the most common causes of both hospitalization and mortality in patients in the pediatric intensive care unit (PICU).
- Trial name
- NCT04419376
- Testing
- driving pressure
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Brain Injuries, Traumatic, Concussion, Brain
Longitudinal Assessment of Post-concussion Driving in Young Adults
Upwards of 3.8 million concussions occur annually in the United States. Driving is a highly complicated activity that requires visual, motor, and cognitive skills, which are commonly impaired after concussion.
- Conditions
- Brain Injuries, Traumatic, Concussion, Brain, Brain Injury Traumatic Mild
- Trial name
- LAPDYA (NCT05942638)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Georgia
Injuries
Reducing Youthful Dangerous Driving
To examine the effectiveness of four motivational counseling groups and a directed observational experience in the emergency room in comparison to education and community volunteering only, in reducing high risk driving behaviors
- Trial name
- RYDD (NCT00852085)
- Testing
- Enhanced community service, Group MI
- Volunteers
- 482 people
- Sponsor
- Rhode Island Hospital
Drug-impaired Driving
Oral Fluid Screening Devices
This research includes the evaluation of a checklist and on-site screening devices to pre-select drivers suspected of being drug-impaired.
- Trial name
- NCT00571207
- Testing
- On-site oral fluid screening devices, Checklist: drug recognition expert
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Driving Impaired, Cognitive Impairment
Dose-response of Cannabis and Driving
Epidemiological studies have established a link between collisions while driving and cannabis use. With the changing legal landscape around cannabis, there is much interest in determining per se limits of cannabis while driving.
- Conditions
- Driving Impaired, Cognitive Impairment, Abuse Cannabis
- Trial name
- NCT03656029
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Acute Respiratory Distress Syndrome
Association Between Driving Transpulmonary Pressure and Extravascular Lung Water in Patients with ARDS
Intubated patients with the acute respiratory distress syndrome (ARDS) are usually treated with protective ventilation limiting plateau pressure below 30 centimeter of water (cmH2O) and, if possible, a driving pressure under 15…
- Trial name
- NCT05474196
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Bicetre Hospital
Neurologic Disorder, Brain Injuries
Comparison of Power Wheelchair Driving Performance Under Immersive and Non-immersive Conditions With Drivers With Neurological Disorders
This study aims to assess the impact of the choice of visual feedback solution (immersive via CAVE and VR headset; non-immersive via screen only) on driving performance and quality of experience on a physical driving simulator…
- Conditions
- Neurologic Disorder, Brain Injuries, Neurodegeneration
- Trial name
- SIMADAPT2 (NCT04894981)
- Testing
- Immersive condition (CAVE), Immersive condition (HMD), Non Immersive condition (Screen alone)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Pôle Saint Hélier
Lung Collapse
Individualized PEEP and Driving Pressure Ventilation on Postoperative Lung Complications in Robot Prostatectomy Surgery
In the case of robotic prostate cancer surgery under general anesthesia, the surgical posture is extreme Trendelenburg. Therefore, airway pressure is very high during mechanical ventilation, and there is a possibility of…
- Trial name
- NCT06909630
- Testing
- Driving pressure group
- Where
- South Korea
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Anxiety, Anxiety Depression
Calming Minds Study
The goal of this study is to understand why certain treatments help people reduce repetitive negative thinking (RNT), which is common in many mental health problems. We want to: 1.
- Conditions
- Anxiety, Anxiety Depression, Worry, Depression
- Trial name
- NCT07577401
- Testing
- Be Specific, Be Kind, Be Present
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of California, Los Angeles
Healthy
Next-Day Residual Effects of Gabapentin, Diphenhydramine and Triazolam on Simulated Driving Performance in Normal Volunteers
This study will examine the next-day residual effects of a nighttime dose of gabapentin 250 mg, diphenhydramine citrate 76 mg and triazolam 0.5 mg compared to placebo and each other on simulated driving performance in normal…
- Trial name
- NCT01888497
- Testing
- Gabapentin, Diphenhydramine citrate, Triazolam
- Where
- 4 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
ADHD
Amphetamine Extended Release Tablets and Driving Performance in Subjects With Attention Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to assess the effect on driving performance of a single dose of amphetamine extended-release tablets (20 mg/tablet) compared with placebo at 45 minutes and 10 hours post-dose in young adults with ADHD.
- Trial name
- NCT04027361
- Testing
- Amphetamine Extended Release (ER) Tablet 20 mg
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Tris Pharma, Inc.
Healthy
Investigate the Effect of Neramexane Mesylate IR Tablet on Driving Fitness and Capability to Operate Machines in Healthy Volunteers
Determination of the ability to drive and operate machines after single and multiple oral dose of Neramexane as compared to placebo
- Trial name
- NCT00712283
- Testing
- Neramexane mesylate
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Merz Pharmaceuticals GmbH
Teamwork
Teamwork for Resilient Staff and Safe Care in ICU
The goal of this ethnographic study is to observe how healthcare professionals work together in an intensive care unit (ICU). The main questions it aims to answer are How do healthcare staff work together in everyday ICU…
- Trial name
- FEARLESS_ICU (NCT06389773)
- Where
- 3 sites in United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King's College London
Drinking and Driving
Alcohol Impaired Driving: From the Laboratory to the Natural Environment
This project combined laboratory and ambulatory assessment (AA) methods to test decision making associated with alcohol impaired driving (AID).
- Trial name
- NCT03846050
- Testing
- BAC feedback/warning, No BAC feedback/warning
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Cannabis
Age Differences in the Effects of Cannabis on Simulated Driving
Epidemiological studies suggest that the use of cannabis is associated with an increase in the risk of motor vehicle collisions. It is also known that younger users may be at increased risk for motor vehicle collisions.
- Trial name
- ADCUF (NCT04325958)
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Driving Impaired, Alcohol Intoxication
Effects of Cannabis/Alcohol on Driving Performance and Field Sobriety Tests
The overarching aim of this study is to examine the impact of acute cannabis and alcohol administration on driving performance, as well as identify methods for detecting driving under the influence of these substances.
- Conditions
- Driving Impaired, Alcohol Intoxication, Driving Under the Influence, Cannabis Intoxication
- Trial name
- NCT05273658
- Testing
- Cannabis, Alcohol
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Solid Tumor (Excluding CNS)
Effect of a Driving Pressure Adjustment Procedure for High-Frequency Jet Ventilation in Patients Undergoing Tumor Thermal Ablation in Interventional Radiology
Tumor thermal ablation under Jet Ventilation is a procedure performed under general anesthesia that enables tumor ablation under radiological imaging guidance.
- Trial name
- Pulmojet 3 (NCT07408375)
- Testing
- High-Frequency Jet Ventilation (HFJV)
- Where
- 7 sites in France
- Volunteers
- 560 people
- Sponsor
- Nantes University Hospital
Transpulmonary Pressure, Pressure.Rate Product
Measuring Lung Pressures in Critically Ill Children Who Are on Mechanical Ventilation
Typically doctors adjust the settings on the ventilator to ensure that children receive enough help to decrease the work they perform to breathe, receive enough oxygen through the machine to pass into the blood and to the organs…
- Conditions
- Transpulmonary Pressure, Pressure.Rate Product, Guide to Mechanical Ventilator Management, Extubation Readiness
- Trial name
- NCT02354365
- Testing
- Transpulmonary Pressure measurement
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Children's Hospital Los Angeles
Insomnia
Effects of Insomnia on Simulated Driving (MK-0000-183-00)
This is a double-blind, parallel design study in elderly primary insomnia patients and demographically matched controls. The objectives if this study are primarily: 1.
- Trial name
- NCT01209728
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC