AnxietyNCT07577401
Calming Minds Study
A study testing Be Specific, Be Kind and Be Present in people with Anxiety and Anxiety Depression, run by University of California, Los Angeles at 1 site in United States.
Trial summary
The goal of this study is to understand why certain treatments help people reduce repetitive negative thinking (RNT), which is common in many mental health problems. We want to: 1. Figure out what actually causes repetitive negative thinking to decrease when people use cognitive-behavioral therapy (CBT). 2. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Anxiety, Anxiety Depression, Worry
- What is being tested?
- Be Specific, Be Kind and Be Present
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 500 participants
- Where
- 1 siteUnited States
- Study dates
- 8 Jun 2026to 14 Jun 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Aged 18+ years
- Able to provide a valid Imperial Valley College email address
- Access to a suitable smartphone/device (iPhone 8+ running iOS 16.4 or higher, or Android version 8 or higher)
- Access to internet
- Elevated repetitive negative thought (RNT) based on scores from Ruminative Response Scale Brood subscale (RSS-brood) and Penn State Worry Questionnaire (PSWQ)
Who cannot join
- Concurrent psychotherapy
- Self-reported current or past diagnosis or treatment for Psychosis
- Self-reported current or past diagnosis or treatment for Bipolar disorder
- Self-reported current or past diagnosis or currently receiving, or waiting to receive, treatment for substance abuse/dependence
- Self-reported current diagnosis or currently receiving, or waiting to receive, treatment for alcohol abuse/dependence
- Antidepressant/anxiolytic medication that has changed in dose or nature in last 6 weeks
- Current severe PTSD defined as measured by the adapted International Trauma Questionnaire
- Active suicidal thoughts or self-harm
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
Imperial Valley College
Imperial, California, 92251
Research Coordinator, (310) 825-8403, calmingminds@mednet.ucla.edu
About this study
Official title: Understanding the Mechanisms Driving the Reduction of Repetitive Negative Thought
The goal of this study is to understand why certain treatments help people reduce repetitive negative thinking (RNT), which is common in many mental health problems. We want to:
- Figure out what actually causes repetitive negative thinking to decrease when people use cognitive-behavioral therapy (CBT).
- Find out which parts of RNT-focused CBT are the most important - the parts that truly make a difference in reducing RNT.
The main result we will look at is how much a person's repetitive negative thought patterns change from the start of the study to the end of treatment (16 weeks). We will measure this using the Perseverative Thinking Questionnaire at baseline and week 16.
Read the detailed description
Participants in this study will be randomly assigned to one of 16 different treatment groups. Each group will get a different mix of 1-5 tools or strategies taken from Rumination-Focused Cognitive Behavioral Therapy (RF-CBT).
All participants, regardless of their treatment assignment, will get a basic set of lessons about repetitive negative thinking (RNT) and how CBT can help. This means every participant gets therapeutic support.
Participants will use a digital therapy program through the MyDataHelps app. The CBT lessons are available in English or Spanish, according to the participant's preference. Each participant will also be offered 3-6 meetings with a coach from our team, to review the lessons and tools in the digital therapy program. It is expected that the digital therapy program and coaching sessions will be completed within 4 months on study. Once 4 months have passed since their start on study, participants are asked to complete online questionnaires that will measure their recent symptom experiences. Participants are then asked to complete these questionnaires again 1 year after starting on study. These questionnaires are used to measure changes in symptom experiences from baseline (before starting the digital therapy program).
In addition to the primary goals listed in the brief summary, this study also aims to look at the following:
- How anxiety and depression symptoms change during their use of the digital therapy program.
- Whether people's mental health symptoms change over time after using the digital therapy program.
- Who benefits most from which components, so therapy can be more personalized in the future.
- Conditions
- Anxiety, Anxiety Depression, Worry, Depression, Rumination - Thoughts
- Being tested
- Be Specific, Be Kind, Be Present, Break Habit, Psychoeducation
- Keywords
- Imperial Valley College, Community College, Depression, Worry, Anxiety, Mental Health, STAND, Calming Minds
- Medical subject headings
- Anxiety Disorders, Depression, Psychological Well-Being
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Be SpecificBehavioural
Digital therapy lessons and coaching that emphasize skills in shifting from unhelpful abstract to helpful concrete processing style. Helping participants make changes to processing style to improve problem-solving and reduce emotional reactivity. Training concrete thinking to reduce RNT by increasing specific contextualized detail in description of events and plans.
Be KindBehavioural
Digital therapy lessons and coaching that emphasize skills for replacing self-criticism with self-compassion. Helping participants shift toward a kinder, more validating way of relating to themselves to reduce the emotional patterns that sustain RNT. Training self-compassion skills to counter harsh self-evaluation and support emotional regulation.
Be PresentBehavioural
Digital therapy lessons and coaching that emphasize skills for improving attention to present-moment experience. Helping participants redirect attention away from unhelpful mental ruminations by strengthening mindfulness and task absorption. Training present-moment awareness to interrupt the cognitive processes that maintain RNT by cultivating absorption in direct sensory experience.
Break HabitBehavioural
Digital therapy lessons and coaching that emphasize skills for disrupting repetitive negative thinking as a habitual mental behavior. Helping participants identify early warning signs, use stimulus-control strategies, form implementation intentions, and practice alternative responses to build more adaptive habits. Training new behavioral and cognitive routines to replace automatic RNT patterns.
PsychoeducationBehavioural
Digital therapy lessons and coaching that provide foundational information about repetitive negative thinking and why it occurs. Helping participants understand explanations for their symptoms and difficulties, which reduces the search for understanding, insight and certainty shown to drive RNT, and normalizes their experiences. This corresponds with the RF-CBT components of individualized rationale, psychoeducation, empathy and understanding.
| Study group | Role | What they receive |
|---|---|---|
| Psychoeducation Only | Active comparator | Participants receive only core psychoeducation without any additional RF-CBT components. Receives: Behavioral: Psychoeducation |
| Be Specific | Experimental | Participants receive training in increasing specificity and concreteness ("Be Specific") in addition to standard psychoeducation. Receives: Behavioral: Be Specific; Behavioral: Psychoeducation |
| Be Kind | Experimental | Participants receive training in self-compassion ("Be Kind") in addition to standard psychoeducation. Receives: Behavioral: Be Kind; Behavioral: Psychoeducation |
| Break Habit | Experimental | Participants receive training in breaking the habit of repetitive negative thinking ("Break Habit") in addition to standard psychoeducation. Receives: Behavioral: Break Habit; Behavioral: Psychoeducation |
| Be Present | Experimental | Participants receive training in absorption in direct experience ("Be Present") in addition to standard psychoeducation. Receives: Behavioral: Be Present; Behavioral: Psychoeducation |
| Be Specific + Be Kind | Experimental | Participants receive training in both specificity/concreteness and self-compassion in addition to standard psychoeducation. Receives: Behavioral: Be Specific; Behavioral: Be Kind; Behavioral: Psychoeducation |
| Be Specific + Be Present | Experimental | Participants receive training in both specificity/concreteness and absorption in direct experience in addition to standard psychoeducation. Receives: Behavioral: Be Specific; Behavioral: Be Present; Behavioral: Psychoeducation |
| Be Kind + Be Present | Experimental | Participants receive training in both self-compassion and absorption in direct experience in addition to standard psychoeducation. Receives: Behavioral: Be Kind; Behavioral: Be Present; Behavioral: Psychoeducation |
| Be Specific + Be Kind + Be Present | Experimental | Participants receive training in specificity/concreteness, self-compassion, and absorption in direct experience in addition to standard psychoeducation. Receives: Behavioral: Be Specific; Behavioral: Be Kind; Behavioral: Be Present; Behavioral: Psychoeducation |
| Break Habit + Be Specific | Experimental | Participants receive training in both breaking the habit of RNT and increasing specificity/concreteness in addition to standard psychoeducation. Receives: Behavioral: Be Specific; Behavioral: Break Habit; Behavioral: Psychoeducation |
| Break Habit + Be Kind | Experimental | Participants receive training in both breaking the habit of RNT and self-compassion in addition to standard psychoeducation. Receives: Behavioral: Be Kind; Behavioral: Break Habit; Behavioral: Psychoeducation |
| Break Habit + Be Specific + Be Kind | Experimental | Participants receive training in breaking the habit of RNT, specificity/concreteness, and self-compassion in addition to standard psychoeducation. Receives: Behavioral: Be Specific; Behavioral: Be Kind; Behavioral: Break Habit; Behavioral: Psychoeducation |
| Break Habit + Be Present | Experimental | Participants receive training in both breaking the habit of RNT and absorption in direct experience in addition to standard psychoeducation. Receives: Behavioral: Be Present; Behavioral: Break Habit; Behavioral: Psychoeducation |
| Break Habit + Be Specific+ Be Present | Experimental | Participants receive training in breaking the habit of RNT, specificity/concreteness, and absorption in direct experience in addition to standard psychoeducation. Receives: Behavioral: Be Specific; Behavioral: Be Present; Behavioral: Break Habit; Behavioral: Psychoeducation |
| Break Habit + Be Kind + Be Present | Experimental | Participants receive training in breaking the habit of RNT, self-compassion, and absorption in direct experience in addition to standard psychoeducation. Receives: Behavioral: Be Kind; Behavioral: Be Present; Behavioral: Break Habit; Behavioral: Psychoeducation |
| ALL | Experimental | Participants receive training in all four RF-CBT components: breaking the habit of RNT, specificity/concreteness, self-compassion, and absorption in direct experience; in addition to standard psychoeducation. Receives: Behavioral: Be Specific; Behavioral: Be Kind; Behavioral: Be Present; Behavioral: Break Habit; Behavioral: Psychoeducation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Perseverative Thinking Questionnaire score from baseline to post-intervention
Change in repetitive negative thought as indexed by the Perseverative Thinking questionnaire
Measured: Baseline, 16 weeks
Secondary outcomes (7)
Change in GAD-7 score from baseline to post-intervention
Change in anxiety measured with GAD-7
Measured: Baseline, 16 weeks & 52 weeks
Change in PHQ-9 score from baseline to post-intervention
Change in depression measured with PHQ-9
Measured: Baseline, 16 weeks & 52 weeks
Change in WEMWBS from baseline to post-intervention
Change in mental wellbeing measured with WEMWBS (Warwick-Edinburgh Mental Wellbeing Scale short-form)
Measured: Baseline, 16 weeks & 52 weeks
Change in RRS-Brooding subscale from baseline to post-intervention
Change in levels of rumination measured with RRS-Brooding subscale
Measured: Baseline, 16 weeks & 52 weeks
Change in PSWQ score from baseline to post-intervention
Change in levels of worry measured with PSWQ (Penn State Worry Questionnaire short-form)
Measured: Baseline, 16 weeks & 52 weeks
Change in WSAS score from baseline to post-intervention
Change in social functioning measured with WSAS (Work and Social Adjustment Scale)
Measured: Baseline, 16 weeks & 52 weeks
Change in EMA from baseline to post-intervention
Change in repetitive negative thought (RNT) in everyday life measured with ecological momentary assessment (EMA) (aggregrate person-level ratings of RNT across 10 day period; variability of RNT; relationship of RNT to mood state \& contextual events; automaticity of RNT, based on EMA items). This provides an ecologically valid measure, in the real-world, of extent of RNT and how it changes pre-to-post intervention.
Measured: Baseline, 16 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 May 2026
- Study start8 Jun 2026 (estimated)
- Primary completion14 Jun 2028 (estimated)
- Study completion14 Jun 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AnxietyStudies of the same condition, open and under way.
- More trials run by University of California, Los AngelesThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Factorial
- Model description
- Participants will be randomized in a factorial design to one of 16 conditions for treatment, each consisting of 1-5 treatment components from Rumination-Focused CBT (RF-CBT). All participants will be exposed to a default core common content (e.g. psychoeducation about RNT and CBT approaches to coping) such that all participants receive a minimal-level intervention.
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 500 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of California, Los Angeles
- Sponsor type
- University, hospital or other
- Collaborators
- University of Exeter
- Responsible party
- Principal investigator, Michelle Craske, University of California, Los Angeles
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07577401
- Sponsor's protocol ID
- IRB-25-1994
- Status last verified
- May 2026
- First submitted
- 3 May 2026
- Last updated
- 11 May 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 11 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Understanding the Mechanisms Driving the Reduction of Repetitive Negative Thought
- ClinicalTrials.gov ID
- NCT07577401
- Acronym / sponsor ID
- IRB-25-1994
- Conditions
- Anxiety, Anxiety Depression, Worry, Depression, Rumination - Thoughts
- Keywords
- Imperial Valley College, Community College, Depression, Worry, Anxiety, Mental Health, STAND, Calming Minds
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 500 participants (estimated)
- Lead sponsor
- University of California, Los AngelesUniversity, hospital or other
- Collaborators
- University of Exeter
- Study start
- 8 Jun 2026 (estimated)
- Primary completion
- 14 Jun 2028 (estimated)
- Study completion
- 14 Jun 2028 (estimated)
- First posted
- 11 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to understand why certain treatments help people reduce repetitive negative thinking (RNT), which is common in many mental health problems. We want to:
- Figure out what actually causes repetitive negative thinking to decrease when people use cognitive-behavioral therapy (CBT).
- Find out which parts of RNT-focused CBT are the most important - the parts that truly make a difference in reducing RNT.
The main result we will look at is how much a person's repetitive negative thought patterns change from the start of the study to the end of treatment (16 weeks). We will measure this using the Perseverative Thinking Questionnaire at baseline and week 16.
Detailed description
Participants in this study will be randomly assigned to one of 16 different treatment groups. Each group will get a different mix of 1-5 tools or strategies taken from Rumination-Focused Cognitive Behavioral Therapy (RF-CBT).
All participants, regardless of their treatment assignment, will get a basic set of lessons about repetitive negative thinking (RNT) and how CBT can help. This means every participant gets therapeutic support.
Participants will use a digital therapy program through the MyDataHelps app. The CBT lessons are available in English or Spanish, according to the participant's preference. Each participant will also be offered 3-6 meetings with a coach from our team, to review the lessons and tools in the digital therapy program. It is expected that the digital therapy program and coaching sessions will be completed within 4 months on study. Once 4 months have passed since their start on study, participants are asked to complete online questionnaires that will measure their recent symptom experiences. Participants are then asked to complete these questionnaires again 1 year after starting on study. These questionnaires are used to measure changes in symptom experiences from baseline (before starting the digital therapy program).
In addition to the primary goals listed in the brief summary, this study also aims to look at the following:
- How anxiety and depression symptoms change during their use of the digital therapy program.
- Whether people's mental health symptoms change over time after using the digital therapy program.
- Who benefits most from which components, so therapy can be more personalized in the future.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 16
- Model description
- Participants will be randomized in a factorial design to one of 16 conditions for treatment, each consisting of 1-5 treatment components from Rumination-Focused CBT (RF-CBT). All participants will be exposed to a default core common content (e.g. psychoeducation about RNT and CBT approaches to coping) such that all participants receive a minimal-level intervention.
| Arm | Type | Receives |
|---|---|---|
| Psychoeducation Only | Active comparator | Behavioral: PsychoeducationParticipants receive only core psychoeducation without any additional RF-CBT components. |
| Be Specific | Experimental | Behavioral: Be Specific, Behavioral: PsychoeducationParticipants receive training in increasing specificity and concreteness ("Be Specific") in addition to standard psychoeducation. |
| Be Kind | Experimental | Behavioral: Be Kind, Behavioral: PsychoeducationParticipants receive training in self-compassion ("Be Kind") in addition to standard psychoeducation. |
| Break Habit | Experimental | Behavioral: Break Habit, Behavioral: PsychoeducationParticipants receive training in breaking the habit of repetitive negative thinking ("Break Habit") in addition to standard psychoeducation. |
| Be Present | Experimental | Behavioral: Be Present, Behavioral: PsychoeducationParticipants receive training in absorption in direct experience ("Be Present") in addition to standard psychoeducation. |
| Be Specific + Be Kind | Experimental | Behavioral: Be Specific, Behavioral: Be Kind, Behavioral: PsychoeducationParticipants receive training in both specificity/concreteness and self-compassion in addition to standard psychoeducation. |
| Be Specific + Be Present | Experimental | Behavioral: Be Specific, Behavioral: Be Present, Behavioral: PsychoeducationParticipants receive training in both specificity/concreteness and absorption in direct experience in addition to standard psychoeducation. |
| Be Kind + Be Present | Experimental | Behavioral: Be Kind, Behavioral: Be Present, Behavioral: PsychoeducationParticipants receive training in both self-compassion and absorption in direct experience in addition to standard psychoeducation. |
| Be Specific + Be Kind + Be Present | Experimental | Behavioral: Be Specific, Behavioral: Be Kind, Behavioral: Be Present, Behavioral: PsychoeducationParticipants receive training in specificity/concreteness, self-compassion, and absorption in direct experience in addition to standard psychoeducation. |
| Break Habit + Be Specific | Experimental | Behavioral: Be Specific, Behavioral: Break Habit, Behavioral: PsychoeducationParticipants receive training in both breaking the habit of RNT and increasing specificity/concreteness in addition to standard psychoeducation. |
| Break Habit + Be Kind | Experimental | Behavioral: Be Kind, Behavioral: Break Habit, Behavioral: PsychoeducationParticipants receive training in both breaking the habit of RNT and self-compassion in addition to standard psychoeducation. |
| Break Habit + Be Specific + Be Kind | Experimental | Behavioral: Be Specific, Behavioral: Be Kind, Behavioral: Break Habit, Behavioral: PsychoeducationParticipants receive training in breaking the habit of RNT, specificity/concreteness, and self-compassion in addition to standard psychoeducation. |
| Break Habit + Be Present | Experimental | Behavioral: Be Present, Behavioral: Break Habit, Behavioral: PsychoeducationParticipants receive training in both breaking the habit of RNT and absorption in direct experience in addition to standard psychoeducation. |
| Break Habit + Be Specific+ Be Present | Experimental | Behavioral: Be Specific, Behavioral: Be Present, Behavioral: Break Habit, Behavioral: PsychoeducationParticipants receive training in breaking the habit of RNT, specificity/concreteness, and absorption in direct experience in addition to standard psychoeducation. |
| Break Habit + Be Kind + Be Present | Experimental | Behavioral: Be Kind, Behavioral: Be Present, Behavioral: Break Habit, Behavioral: PsychoeducationParticipants receive training in breaking the habit of RNT, self-compassion, and absorption in direct experience in addition to standard psychoeducation. |
| ALL | Experimental | Behavioral: Be Specific, Behavioral: Be Kind, Behavioral: Be Present, Behavioral: Break Habit, Behavioral: PsychoeducationParticipants receive training in all four RF-CBT components: breaking the habit of RNT, specificity/concreteness, self-compassion, and absorption in direct experience; in addition to standard psychoeducation. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Aged 18+ years
- Able to provide a valid Imperial Valley College email address
- Access to a suitable smartphone/device (iPhone 8+ running iOS 16.4 or higher, or Android version 8 or higher)
- Access to internet
- Elevated repetitive negative thought (RNT) based on scores from Ruminative Response Scale Brood subscale (RSS-brood) and Penn State Worry Questionnaire (PSWQ)
Key exclusion criteria (8 listed)
- Concurrent psychotherapy
- Self-reported current or past diagnosis or treatment for Psychosis
- Self-reported current or past diagnosis or treatment for Bipolar disorder
- Self-reported current or past diagnosis or currently receiving, or waiting to receive, treatment for substance abuse/dependence
- Self-reported current diagnosis or currently receiving, or waiting to receive, treatment for alcohol abuse/dependence
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Be SpecificDigital therapy lessons and coaching that emphasize skills in shifting from unhelpful abstract to helpful concrete processing style. Helping participants make changes to processing style to improve problem-solving and reduce emotional reactivity. Training concrete thinking to reduce RNT by increasing specific contextualized detail in description of events and plans. | Behavioural | ALL, Be Specific, Be Specific + Be Kind, Be Specific + Be Kind + Be Present, Be Specific + Be Present, Break Habit + Be Specific, Break Habit + Be Specific + Be Kind, Break Habit + Be Specific+ Be Present |
| Be KindDigital therapy lessons and coaching that emphasize skills for replacing self-criticism with self-compassion. Helping participants shift toward a kinder, more validating way of relating to themselves to reduce the emotional patterns that sustain RNT. Training self-compassion skills to counter harsh self-evaluation and support emotional regulation. | Behavioural | ALL, Be Kind, Be Kind + Be Present, Be Specific + Be Kind, Be Specific + Be Kind + Be Present, Break Habit + Be Kind, Break Habit + Be Kind + Be Present, Break Habit + Be Specific + Be Kind |
| Be PresentDigital therapy lessons and coaching that emphasize skills for improving attention to present-moment experience. Helping participants redirect attention away from unhelpful mental ruminations by strengthening mindfulness and task absorption. Training present-moment awareness to interrupt the cognitive processes that maintain RNT by cultivating absorption in direct sensory experience. | Behavioural | ALL, Be Kind + Be Present, Be Present, Be Specific + Be Kind + Be Present, Be Specific + Be Present, Break Habit + Be Kind + Be Present, Break Habit + Be Present, Break Habit + Be Specific+ Be Present |
| Break HabitDigital therapy lessons and coaching that emphasize skills for disrupting repetitive negative thinking as a habitual mental behavior. Helping participants identify early warning signs, use stimulus-control strategies, form implementation intentions, and practice alternative responses to build more adaptive habits. Training new behavioral and cognitive routines to replace automatic RNT patterns. | Behavioural | ALL, Break Habit, Break Habit + Be Kind, Break Habit + Be Kind + Be Present, Break Habit + Be Present, Break Habit + Be Specific, Break Habit + Be Specific + Be Kind, Break Habit + Be Specific+ Be Present |
| PsychoeducationDigital therapy lessons and coaching that provide foundational information about repetitive negative thinking and why it occurs. Helping participants understand explanations for their symptoms and difficulties, which reduces the search for understanding, insight and certainty shown to drive RNT, and normalizes their experiences. This corresponds with the RF-CBT components of individualized rationale, psychoeducation, empathy and understanding. | Behavioural | ALL, Be Kind, Be Kind + Be Present, Be Present, Be Specific, Be Specific + Be Kind, Be Specific + Be Kind + Be Present, Be Specific + Be Present, Break Habit, Break Habit + Be Kind, Break Habit + Be Kind + Be Present, Break Habit + Be Present, Break Habit + Be Specific, Break Habit + Be Specific + Be Kind, Break Habit + Be Specific+ Be Present, Psychoeducation Only |
Primary outcome
Change in Perseverative Thinking Questionnaire score from baseline to post-intervention
Time frame: Baseline, 16 weeks
Change in repetitive negative thought as indexed by the Perseverative Thinking questionnaire
7 secondary outcomes
Change in GAD-7 score from baseline to post-intervention
Time frame: Baseline, 16 weeks & 52 weeks
Change in PHQ-9 score from baseline to post-intervention
Time frame: Baseline, 16 weeks & 52 weeks
Change in WEMWBS from baseline to post-intervention
Time frame: Baseline, 16 weeks & 52 weeks
Change in RRS-Brooding subscale from baseline to post-intervention
Time frame: Baseline, 16 weeks & 52 weeks
Change in PSWQ score from baseline to post-intervention
Time frame: Baseline, 16 weeks & 52 weeks
Change in WSAS score from baseline to post-intervention
Time frame: Baseline, 16 weeks & 52 weeks
Change in EMA from baseline to post-intervention
Time frame: Baseline, 16 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 May 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Be Specific, Be Kind and Be Present in people with Anxiety and Anxiety Depression, run by University of California, Los Angeles at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 11 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Perseverative Thinking Questionnaire score from baseline to post-intervention (time frame: Baseline, 16 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 May 2026.