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Condition

Anxiety Clinical Trials

Studies of anxiety, matched by condition name and medical subject headings. Start with those open to enrolment.

8,510 registered studies

In numbers

Open to volunteers
1,678
Active
1,947
All registered
8,510

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 1,678
  • Generalized Anxiety Disorder (GAD), Depressive and Anxiety Disorders

    Miles for Mental Health

    • Not yet recruiting
    • Age: 18 years and older
    • Lifestyle or therapy programme

    Common mental health disorders, like anxiety and depression, are widespread among the American population. The prevalence of mental health disorders among adults continues has consistently increased from previous decades and is…

    Trial name
    NCT07541443
    Testing
    Exercise
    Volunteers
    20 people
    Sponsor
    Emporia State University
    Can I take part? NCT07541443
  • Preoperative Anxiety, Orthopedic Surgery

    Preoperative Anxiety and One-year Patient-reported Outcomes in Orthopedic Surgery Patients Receiving Enhanced Recovery After Surgery or Conventional Care

    • Recruiting
    • Age: 20 to 100 years
    • Observational study
    • Pill or oral medicine

    This study investigates whether an Enhanced Recovery After Surgery (ERAS) program can help orthopedic surgery patients feel less anxious before their operation and recover better one year after surgery, compared to conventional…

    Conditions
    Preoperative Anxiety, Orthopedic Surgery, Patient Reported Outcome (PRO)
    Trial name
    ERAS-APO (NCT07706244)
    Testing
    Enhanced Recovery After Surgery (ERAS) pathway, Conventional care group
    Where
    Taiwan
    Volunteers
    220 people
    Sponsor
    Buddhist Tzu Chi General Hospital
    Can I take part? ERAS-APO
  • Major Depression, Generalized Anxiety

    Neural Mechanisms of Real-world Emotions and Internalizing

    • Recruiting
    • Age: 18 to 35 years
    • Lifestyle or therapy programme

    This study utilizes mobile health methods, including smartphone technology, subjective self-reports measures of emotion, behavioral tasks, functional Magnetic Resonance Imaging (fMRI), physiological measures of attention and…

    Conditions
    Major Depression, Generalized Anxiety, Emotions
    Trial name
    NCT07891624
    Testing
    Academic Performance Feedback
    Where
    United States
    Volunteers
    144 people, healthy volunteers welcome
    Sponsor
    University of Miami
    Can I take part? NCT07891624
  • Depression and/or Anxiety Symptoms, Problematic Phone Use Behavior

    The Mindful Smartphone Use Study

    • Recruiting
    • Age: 13 to 19 years
    • Lifestyle or therapy programme

    The goal of this clinical trial is to understand the feasibility and acceptability on a mindfulness-based intervention to address co-existing smartphone addiction and psychological distress among adolescents ages 13-19…

    Trial name
    NCT07892807
    Testing
    Mindwire
    Where
    United States
    Volunteers
    40 people
    Sponsor
    Brown University
    Can I take part? NCT07892807
  • Panic Disorder, Agoraphobia

    A Clinical Trial to Evaluate the Efficacy and Safety of Meltz, a Digital Therapeutic Device, for Improving Panic Symptoms in Patients With Panic Disorder

    • Not yet recruiting
    • Age: 19 to 64 years
    • Medical device

    i. This randomized clinical trial will evaluate the efficacy and safety of Meltz, a digital therapeutic device that provides cognitive behavioral therapy (CBT) for adults with panic disorder. ii.

    Trial name
    Meltz (NCT07892885)
    Testing
    Meltz
    Volunteers
    120 people
    Sponsor
    AIMNEXT
    Can I take part? Meltz
  • Depression, Anxiety

    Evaluation of the PACE/PACENET BHL Clinical Program

    • Recruiting
    • Age: 65 years and older
    • Observational study
    • Lifestyle or therapy programme

    The SUpporting Seniors Receiving Treatment And INtervention (SUSTAIN) program is a telephone-based clinical service designed to help identify and manage behavioral health issues among PACE/PACENET enrollees.

    Conditions
    Depression, Anxiety, Pain, Chronic
    Trial name
    SUSTAINIV (NCT02463266)
    Testing
    SUSTAIN Monitoring and Care Management
    Where
    United States
    Volunteers
    4,000 people
    Sponsor
    University of Pennsylvania
    Can I take part? SUSTAINIV
  • Parenting Stress, Mental Health

    Development & Validation of a Life Balance Program for Parents of Preschoolers: A Pilot Study

    • Recruiting
    • Age: 18 to 65 years
    • Lifestyle or therapy programme

    This study aims to examine the relationships among life balance, parenting stress, and mental health in parents of preschool children, and to develop an individualized life balance promotion program for this population.

    Conditions
    Parenting Stress, Mental Health, Occupational Balance
    Trial name
    NCT07669896
    Testing
    Occupational Balance Promotion Program
    Where
    Taiwan
    Volunteers
    30 people, healthy volunteers welcome
    Sponsor
    Chung Shan Medical University
    Can I take part? NCT07669896
  • Postoperative Pain After Endodontic Treatment, Dental Anxiety

    Effect of Intracanal Cryotherapy on Pain, Anxiety, and Salivary Irisin After Root Canal Treatment

    • Not yet recruiting
    • Age: 18 to 65 years
    • Surgery or procedure

    Some people feel pain after a root canal treatment. This study will test whether intracanal cryotherapy, a final rinse of the tooth with cold sterile saline, can reduce this pain compared with a room-temperature rinse.

    Conditions
    Postoperative Pain After Endodontic Treatment, Dental Anxiety, Root Canal Treatment
    Trial name
    CRYO-IRIS (NCT07889050)
    Testing
    Intracanal Cryotherapy, Standard Room-Temperature Irrigation
    Where
    Turkey (Türkiye)
    Volunteers
    130 people, healthy volunteers welcome
    Sponsor
    Alanya Alaaddin Keykubat University
    Can I take part? CRYO-IRIS
  • Podcast, Nursing Students

    Podcast-supported Education on Climate Change Awareness, Anxiety, and Health Literacy Levels in Nursing Students

    • Not yet recruiting
    • Age: 18 years and older
    • Lifestyle or therapy programme

    The study was designed with a parallel-group randomized controlled experimental design to determine the effects of podcast-based education on climate change awareness and climate change health literacy levels of nursing students.

    Conditions
    Podcast, Nursing Students, Climate Change Awareness, Climate Change Anxiety
    Trial name
    NCT07889713
    Testing
    Podcast-Based Educational Intervention
    Volunteers
    100 people, healthy volunteers welcome
    Sponsor
    Gazi University
    Can I take part? NCT07889713
  • Empathy, Anxiety

    Psychosocial Effects of Empathy-Based Midwifery Education on Midwifery Students and Pregnant Women

    • Not yet recruiting
    • Age: 18 years and older
    • Lifestyle or therapy programme

    This two-stage quasi-experimental study will evaluate the effects of empathy-based midwifery education on midwifery students' empathy and anxiety, and on women's satisfaction with childbirth and perceptions of traumatic birth.

    Conditions
    Empathy, Anxiety, Childbirth
    Trial name
    PEEBMEMSPW (NCT07889986)
    Testing
    Empathy-Based Midwifery Education, Empathy-Based Midwifery Support During Labor
    Volunteers
    224 people, healthy volunteers welcome
    Sponsor
    Kahramanmaras Sutcu Imam University
    Can I take part? PEEBMEMSPW

Completed, with results posted

All –
  • Cancer, Quality of Life

    The PRISM Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults With Advanced Cancer

    • Completed
    • Age: 12 to 24 years
    • Lifestyle or therapy programme
    • Results posted

    Multi-Site Randomized Controlled Trial testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults with Advanced Cancer

    Conditions
    Cancer, Quality of Life, Anxiety, Depression
    Trial name
    PRISM-AC (NCT03668223)
    Testing
    Promoting Resilience in Stress Management (PRISM)
    Where
    5 sites in United States
    Volunteers
    269 people
    Sponsor
    Dana-Farber Cancer Institute
    Can I take part? PRISM-AC
  • Anxiety, Depression

    Factorial Optimization Trial to Test Effects of Coping Intervention Components

    • Completed
    • Age: 9 to 12 years
    • Lifestyle or therapy programme
    • Results posted

    This study will identify components for inclusion in a coping intervention package to reduce mental health problems among children exposed to high interparental conflict after parental separation/divorce.

    Conditions
    Anxiety, Depression, Coping Skills, Emotional Problem
    Trial name
    NCT05822687
    Testing
    Education, Reappraisal Coping, Distraction Coping
    Where
    United States
    Volunteers
    148 people
    Sponsor
    Arizona State University
    Can I take part? NCT05822687
  • Depression, Anxiety

    HIV Engagement and Adolescent Depression Support (HEADS-UP)

    • Completed
    • Age: 13 to 18 years
    • Lifestyle or therapy programme
    • Results posted

    This pilot study will individually randomize 105 adolescents living with HIV 1:1:1 to standard of care, adapted intervention, or enhanced intervention.

    Conditions
    Depression, Anxiety, Adolescent Behavior, HIV Infections
    Trial name
    HEADS-UP (NCT06173544)
    Testing
    Standard of Care (SOC), Adapted Friendship Bench (AFB), Enhanced Friendship Bench (EFB)
    Where
    5 sites in Malawi
    Volunteers
    106 people
    Sponsor
    University of North Carolina, Chapel Hill
    Can I take part? HEADS-UP
  • Anxiety, Insomnia

    Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults

    • Completed
    • Age: 65 years and older
    • Results posted

    The main purpose of this 12-week study is to see if a new combination of treatments can help older adults reduce benzodiazepine or related medication use.

    Conditions
    Anxiety, Insomnia, Benzodiazepine, Deprescription
    Trial name
    NCT06197243
    Testing
    Acupuncture, Yoga, Deprescribing
    Where
    United States
    Volunteers
    23 people, healthy volunteers welcome
    Sponsor
    Vanderbilt University Medical Center
    Can I take part? NCT06197243
  • Social Anxiety Disorder of Childhood

    Targeting Attention Orienting to Social Threat to Reduce Social Anxiety in Youth

    • Completed
    • Age: 10 to 14 years
    • Lifestyle or therapy programme
    • Results posted

    This two-site study is a test of Attention Bias Modification Treatment (ABMT) among 260 youths ages 10 to 14 years with social anxiety disorder.

    Trial name
    NCT03932032
    Testing
    Attention Bias Modification Treatment, Neutral Control Task
    Where
    2 sites in United States
    Volunteers
    206 people
    Sponsor
    Florida International University
    Can I take part? NCT03932032

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