Clinical trials: D-dimer
Covid-19
Clinical Trial on the Efficacy and Safety of Bemiparin in Patients Hospitalized Because of COVID-19
The 2019 coronavirus disease (Covid-19) is a new disease caused by the SARS-CoV2 virus of which many things are not yet known. Among others, there is a need to define the best therapeutic strategy to treat Covid-19, improving…
- Trial name
- NCT04420299
- Testing
- Bemiparin
- Where
- 2 sites in Spain
- Volunteers
- 81 people
- Sponsor
- Fundación de investigación HM
Acute Pulmonary Embolism
Clinical Scores, Biomarkers, and CT Findings in Acute Pulmonary Embolism
This study aims to compare clinical scoring systems, laboratory biomarkers, and computed tomography (CT) findings in patients diagnosed with acute pulmonary embolism in different hospital departments.
- Trial name
- PEST (NCT07566858)
- Testing
- No Intervention (Observational Study Data Collection)
- Volunteers
- 50 people
- Sponsor
- Sohag University
COVID-19
Serum Level of Ferritin and D-dimer and the Severity of (COVID 19) Infection
Many laboratory biomarkers were used for diagnosis of COVID-19 infection; however, their accuracy to assess the severity and prognosis are still to be evaluated.
- Trial name
- NCT05672810
- Testing
- serum level of Ferritin and D-dimer
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Cardiovascular Diseases, COVID-19
Safety and Efficacy of Therapeutic Anticoagulation on Clinical Outcomes in Hospitalized Patients With COVID-19
The coronavirus disease 2019 (COVID-19) global pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused considerable morbidity and mortality in over 170 countries.
- Trial name
- NCT04377997
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Massachusetts General Hospital
Deep Vein Thrombosis
Systematic Machine Learning Algorithm for Rapid Thrombosis Detection
The goal of this clinical trial is to compare the use of a machine learning-based algorithm and point-of-care D-dimer to laboratory D-dimer and compression ultrasound to exclude deep vein thrombosis in the under extremities in…
- Trial name
- DVT-SMART (NCT06842446)
- Testing
- POC D-dimer, POC ultrasound, Machine learning model
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Ostfold Hospital Trust
Aortic Dissection
Aortic Dissection Detection Risk Score Plus D-dimer in Suspected Acute Aortic Dissection
Acute aortic dissection (AD) is a deadly, difficult to diagnose disease presenting with an array of common and unspecific symptoms.
- Trial name
- ADvISED (NCT02086136)
- Where
- 6 sites in Brazil, Germany and 2 more
- Volunteers
- 1,900 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Coronary Artery Disease, Percutaneous Coronary Intervention
NOAC Therapy Guided by PARIS Risk Score and D-dimer in Patients With ACS After PCI
The goal of this clinical trial is to compare short-term Triple Antithrombotic Therapy (DAPT + Rivaroxaban) followed by DAPT with standard DAPT in selected ACS patients with high ischemic risk.
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Coronary Syndrome
- Trial name
- NCT05638867
- Testing
- Aspirin + Clopidogrel + Rivaroxaban, Aspirin + Clopidogrel
- Where
- China
- Volunteers
- 3,944 people
- Sponsor
- China National Center for Cardiovascular Diseases
End Stage Renal Disease on Dialysis
Assessment of D-dimer and CRP for Cardiovascular Risk Prediction in Hemodialysis Patients
This study aims to assess whether two blood markers - C-reactive protein (CRP) and D-dimer - can help predict cardiovascular complications in patients undergoing regular hemodialysis.
- Trial name
- BIOCARD-HD (NCT07130721)
- Testing
- C-Reactive Protein (CRP) Test, D-dimer Test, Electrocardiogram (ECG)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Infection, Acute Coronary Syndrome
Association Between Levels of D-Dimer, Fibrinogen and PAI-1 in Elderly Patients With Infection and Occurrence of Cardio- and Cerebro-vascular Disease After Discharge
The association between the levels of d-dimer, fibrinogen and PAI-1 in plasma of elderly patients admitted to internal medicine departments because of infection and the occurrence of cardio- and cerebro-vascular disease after…
- Conditions
- Infection, Acute Coronary Syndrome, Cerebrovascular Disease
- Trial name
- NCT00512603
- Volunteers
- 52 people
- Sponsor
- Wolfson Medical Center
Pulmonary Thromboembolism
Thromboembolic Events in Severe COVID-19 Patients
The main objective of this study is to describe the incidence of thromboembolic events in a population of patients hospitalized in intensive care units in France for severe COVID-19.
- Trial name
- COVICLOT (NCT04405869)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Adnexal Torsion
Role of Preoperative D-dimer Levels in the Diagnosis of Adnexal Torsion
Adnexal torsion is the fifth most common gynecologic emergency. Thirty percent of all cases of adnexal torsion occur in females younger than 20 years.
- Trial name
- NCT06324565
- Testing
- D-Dimer test
- Where
- 9 sites in Austria, Italy and 1 more
- Volunteers
- 130 people
- Sponsor
- IRCCS Burlo Garofolo
Chronic Urticaria
Antiplatelet Therapy in Chronic Urticaria
This study compares the combination of antiplatelets and antihistamine versus antihistamine alone for the treatment of chronic spontaneous urticaria
- Trial name
- NCT06268470
- Testing
- Desloratadine plus cilostazol and dipyridamole, Desloratadine
- Where
- Thailand
- Volunteers
- 12 people
- Sponsor
- Chulalongkorn University
Pulmonary Embolism
Thrombus Localization and Accompaying Disorders and Risk Factors
ABSTRACT Pulmonary embolism shows a wide spectrum ranging from clinically asymptomatic thrombus to massive thrombus, leading to cardiogenic shock.
- Trial name
- NCT02388841
- Testing
- Pulmonary embolism
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Aysel Sünnetçioğlu
Pulmonary Embolism (PE)
Soluble Fibrin for Diagnosing Pulmonary Embolism
The purpose of the study is to evaluate the performances of Soluble Fibrin for diagnosing Pulmonary Embolism. Secondary objective is to compare the diagnostic performances of the Soluble Fibrin Assay and the D-Dimer test.
- Trial name
- SOFIE (NCT02438462)
- Testing
- Soluble Fibrin
- Where
- France
- Volunteers
- 480 people
- Sponsor
- Diagnostica Stago R&D
Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate (TURP)
Spinal Versus General Anesthesia on Coagulation and Fibrinolysis During Transurethral Resection of the Prostate
This prospective randomized clinical trial aims to compare the effects of spinal and general anesthesia on perioperative coagulation and fibrinolysis in patients undergoing elective transurethral resection of the prostate (TURP).
- Trial name
- NCT07734233
- Testing
- Spinal Anesthesia (bupivacaine), General Anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Haseki Training and Research Hospital
Anticoagulant Reversal, Reversal of Edoxaban Induced Anticoagulation
Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban
PER977 monotherapy and co-administration following 60 mg edoxaban will have an acceptable safety and tolerability profile with no impact on pro-coagulant biomarkers.
- Trial name
- PER977-P1 (NCT01826266)
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc.
COVID-19 Infection, Parathyroid Gland
The Status of Parathyroid Hormone Secretion in Covid-19 Patients
COVID-19 infection causes a hypersensitive immune reaction and widespread inflammation in various organs of the body, especially through cytokines in the lungs.
- Conditions
- COVID-19 Infection, Parathyroid Gland, Parathyroid Hormone, Calcium
- Trial name
- NCT04662437
- Testing
- Venous blood was collected for biochemistry testing
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Suspected Deep Vein Thrombosis
The Designer D-dimer Deep Vein Thrombosis Diagnosis (4D) Study
This is a cohort study that will assess a new diagnostic management strategy for suspected Deep Vein Thrombosis in outpatients.The new diagnostic strategy is designed to reduce the use of ultrasound testing on the day of…
- Trial name
- 4D (NCT02038530)
- Where
- 10 sites in Canada
- Volunteers
- 1,513 people
- Sponsor
- McMaster University
Extracorporeal Membrane Oxygenation Complication, Thrombosis
D-dimer to Improve Anticoagulation Outcome During ECMO loNg-term supporteD
This was a prospective, cohort study.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Thrombosis, Hemorrhage, Heparin Overdose
- Trial name
- DIAMOND (NCT03261284)
- Testing
- D-dimer-guided adjustment stratege, Thepeautic-heparin therapy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Wuhan Asia Heart Hospital
Deep Vein Thrombosis of the Lower Extremities
The ERASMUS Study: Limited vs Extended US for DVT Diagnosis
Currently, patients with suspected deep vein thrombosis (DVT) of the lower extremities receive the ultrasound investigation of their deep vein system, either by limited ultrasonography (ultrasonography confined to the proximal…
- Trial name
- NCT00353093
- Testing
- Ultrasonography of the deep vein system of the legs
- Volunteers
- 2,000 people
- Sponsor
- University of Padova