Clinical trials: Coronary Bifurcation Lesion
Coronary Artery Disease
A Study of the Cypher Sirolimus-Eluting Stent to Treat Bifurcation Lesions.
The objective of this study is to assess the feasibility and safety of the sirolimus-coated Bx VELOCITY Balloon-Expandable Stent in treating patients with true bifurcation lesions.
- Trial name
- BIFURCATION (NCT00234455)
- Testing
- drug eluting-stent, drug-eluting stent
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- Cordis US Corp.
Bifurcation Coronary Disease
AngioSculpt Scoring Balloon Catheter For Bifurcation Coronary Lesions (ABC Study)
Assess the impact of lesion preparation using the AngioSculpt balloon in the treatment of bifurcation lesions in native coronary arteries.
- Trial name
- ABC (NCT00914979)
- Testing
- AngioSculpt
- Where
- 4 sites in Israel
- Volunteers
- 7 people
- Sponsor
- HaEmek Medical Center, Israel
Coronary Artery Disease
Multislice CT Angiography of Coronary Bifurcations and Outcomes After Intervention
This is prospective, observational study, that will be conducted in two high-volume university interventional cardiology centers.
- Trial name
- NCT01943643
- Testing
- multislice CT angiography
- Where
- Serbia
- Volunteers
- 70 people
- Sponsor
- Clinical Hospital Center Zemun
Coronary Artery Disease
Treatment of Bifurcated Coronary Lesions With Cypher™-Stent
This study is a prospective, randomized, single-center evaluation of the Cypher™ Sirolimus eluting coronary stent system in the treatment of de novo bifurcated coronary lesions comparing provisional modified T stenting with…
- Trial name
- NCT00288535
- Testing
- PCI of bifurcated coronary lesions using sirolimus coated stents in modified T-Stenting -Technique
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Heart Center Freiburg - Bad Krozingen
Coronary Artery Disease
Smart Angioplasty Research Team-Optimal Strategy for Side Branch Stenting in Coronary Bifurcation Lesion With Drug-Coated Balloon
A prospective, multi-center, open-label, randomized controlled, superiority trial. The aim of the study is to compare clinical outcomes between upfront 2-stenting strategy versus upfront drug-coated balloon (DCB)-based hybrid…
- Trial name
- SMART-DCB (NCT07019350)
- Testing
- Upfront DCB-based hybrid strategy, Upfront 2-stenting strategy
- Where
- 3 sites in South Korea
- Volunteers
- 520 people
- Sponsor
- Samsung Medical Center
Ischemia; Heart, Stents
Immediate and Short Term Outcomes for Using Drug Coated Balloons in Treating Coronary Bifurcation Lesions
● the investigators aims to study the impact of using drug coated balloon in coronary artery bifurcation lesions on the procedural success rate \& short-term MACE.
- Trial name
- DCB (NCT05872074)
- Testing
- Coronary angiography plus percutenous coronary intervention
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Bifurcation Lesions, Drug Eluting Balloon
Bingo Drug-eluting Balloon in Bifurcation
The purpose is to observe and evaluate the safety and efficacy of Bingo drug-eluting balloon in the treatment of patients with bifurcation lesions of coronary artery.
- Trial name
- NCT02325817
- Testing
- Drug-eluting balloon, Uncoated ballloon
- Where
- China
- Volunteers
- 222 people
- Sponsor
- Yinyi(Liaoning) Biotech Co., Ltd.
Coronary Artery Disease
Baseline V-RESOLVE Score Guided Versus Angiography Guided Stent Implantation in Coronary Bifurcation Lesions (CIT-RESOLVE II)
The purpose of this study is to investigate whether baseline V-RESOLVE score guided intervention is associated with significant reduction of side branch occlusion rates compared to angiography guided intervention in patients with…
- Trial name
- NCT05503407
- Testing
- Baseline V-RESOLVE score-guided PCI, Angiography-guided PCI
- Where
- China
- Volunteers
- 1,104 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Disease
Choice Of Optimal Strategy For Bifurcation Lesions With Normal Side Branch
Few data are available about the late patency of side branches in association with the currently used stent types and implantation techniques.
- Trial name
- CROSS (NCT00694005)
- Testing
- kissing balloon, without kissing balloon angioplasty "leave alone"
- Where
- 11 sites in South Korea
- Volunteers
- 504 people
- Sponsor
- Seung-Jung Park
Coronary Bifurcation Lesions
Treatment Of Coronary Bifurcation Lesions: Stentcovering Of The Side Branch With And Without PCI Of The Side Branch: A Retrospective Analysis Of All Consecutive Patients
This retrospective observational study included patients (pts) with percutaneous coronary intervention (PCI) of a de novo coronary bifurcation lesion in one German center between January 2008 - August 2011.
- Trial name
- NCT01538186
- Where
- Germany
- Volunteers
- 98 people
- Sponsor
- Krankenhaus Hetzelstift
Coronary Artery Disease, Ischemic Heart Disease
Comparing T-stenting And Minimal Protrusion With External Minicrush for Treatment of Complex Coronary Bifurcation
Nowadays, no studies compare the T-stenting And Minimal Protrusion (TAP) and External Minicrush techniques in treating complex coronary bifurcation, so eventually, procedural, clinical and safety differences remain unknown.
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Chronic Coronary Syndrome, Acute Coronary Syndrome
- Trial name
- NCT06484647
- Testing
- Percutaneous Coronary Intervention
- Where
- Italy
- Volunteers
- 382 people
- Sponsor
- San Luigi Gonzaga Hospital
Angioplasty, Percutaneous Coronary Intervention
Palpitate-Eluting Balloon Angioplasty in the Treatment of Coronary Bifurcation Lesion Evaluated by OCT
The aim of the study is to use optical coherence tomography (OCT) to investigate the efficacy of Paclitaxel-eluting PTCA-balloon dilation (SeQuent Please) in SB and drug eluting stent (EXCEL stent) deployment in the main branch…
- Trial name
- PEBCBLO (NCT02276846)
- Testing
- Paclitaxel-Eluting Balloon
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Hospital of Jilin University
Stable Angina
Outcome of Coronary High Angulated Bifurcation Lesions Treated With Kissing Ballooning or Sequential Ballooning Techniques
Coronary artery bifurcation lesions prone to occur with the worsening of atherosclerosis. Their structural properties make angioplasty technique to increase the difficulty of implementation, but also increased the risks of the…
- Trial name
- MV:main branch (NCT02137486)
- Where
- Taiwan
- Volunteers
- 214 people
- Sponsor
- Taipei City Hospital
Coronary Artery Disease
A Study of Drug Coated Balloon For Treating the Side Branch in Complex Bifurcation Lesions
Hypothesis: In patients undergoing coronary stenting for the true bifurcation lesions, main branch stenting followed by side branch dilatation with drug coated balloon is superior to the provisional-stenting strategy in terms of…
- Trial name
- STENT-FREE (NCT05222061)
- Testing
- Drug coated balloon for the side brunch, Conventional balloon for the side brunch
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Safety Issues, Efficacy, Self
Lower Silesia Culotte Bifurcation Registry (LSCBR).
The study aimed to evaluate the outcomes of bifurcation PCI using two techniques (Culotte vs. DK-Culotte) using data from a retrospective analysis.
- Trial name
- LSCBR (NCT06284057)
- Testing
- Bifurcation PCI with two stent technique Culotte Technique or Double Kiss (DK) Culotte
- Where
- 2 sites in Poland
- Volunteers
- 400 people
- Sponsor
- Miedziowe Centrum Zdrowia SA
Coronary Artery Disease (CAD), Coronary Bifurcation Lesion
Stenting Versus Drug Eluting Balloons Only in Treatment of Coronary Bifurcation Lesion (ROBUST Study)
The goal of this clinical trial is to learn immediate and follow up results of percutaneous treatment of coronary bifurcation lesion using drug eluting balloons (DEB) only in patients with chronic coronary syndrome (CCS).
- Conditions
- Coronary Artery Disease (CAD), Coronary Bifurcation Lesion, Coronary Stenting, Drug Eluting Balloon
- Trial name
- ROBUST (NCT07552194)
- Testing
- Balloon Angioplasty with or without drug administration
- Volunteers
- 272 people
- Sponsor
- Avtandil M. Babunashvili
Coronary Angiography
Predilation of Side Branch During Percutaneous Treatment of Bifurcation Lesions With Provisional T Stenting
Percutaneous treatment of bifurcation lesion is a complex procedure. After main vessel stent implantation, the side branch became jailed and the carina can be displaced resulting in complete occlusion of this vessel.
- Trial name
- NCT01090856
- Testing
- Pre-dilation side branch
- Where
- Spain
- Volunteers
- 420 people
- Sponsor
- Fundación Pública Andaluza Progreso y Salud
Coronary Bifurcation Lesions
Optical Coherence Tomography (OCT) Findings and Coronary Bifurcation Lesions
To determine the clinical prevalence of vulnerable plaque using OCT in patients with coronary bifurcation lesion.
- Trial name
- NCT03172845
- Testing
- percutaneous coronary intervention
- Where
- China
- Volunteers
- 304 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Bifurcation Lesion, Coronary Artery Disease
INSPIRON Sirolimus Eluting Stent Performance in Bifurcation Coronary Arteries Treated Using Provisional Technique
Evaluate the efficacy of the Inspiron Sirolimus Eluting Stent on bifurcation coronary artery lesions, in order to preserve and not compromize the side branch using the provisional stent technique.
- Trial name
- insProvisional (NCT03780192)
- Testing
- Inspiron Sirolimus Eluting Stent
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Scitech Produtos Medicos SA
Coronary Artery Disease, Myocardial Ischemia
AngioSculpt® Coronary Bifurcation Study
The purpose of this study is to evaluate a new angioplasty catheter, AngioSculpt® for the treatment of bifurcation lesions (blockages occurring at branch points) in coronary arteries.
- Trial name
- AGILITY (NCT00686647)
- Testing
- AngioSculpt® Scoring Balloon Catheter, AngioSculpt Scoring Balloon Catheter
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- AngioScore, Inc.